[←][→] rno  Htr2c Gene
functional annotation
Function   5-hydroxytryptamine receptor 2C  
GO BP
GO:0031583 [list] [network] phospholipase D-activating G protein-coupled receptor signaling pathway  (2 genes)  IMP  
GO:0007208 [list] [network] phospholipase C-activating serotonin receptor signaling pathway  (3 genes)  IDA ISO  
GO:0010513 [list] [network] positive regulation of phosphatidylinositol biosynthetic process  (3 genes)  ISO  
GO:0014057 [list] [network] positive regulation of acetylcholine secretion, neurotransmission  (3 genes)  IMP  
GO:0043397 [list] [network] regulation of corticotropin-releasing hormone secretion  (4 genes)  ISO ISS  
GO:0045963 [list] [network] negative regulation of dopamine metabolic process  (4 genes)  IMP  
GO:0014054 [list] [network] positive regulation of gamma-aminobutyric acid secretion  (7 genes)  IMP  
GO:0035095 [list] [network] behavioral response to nicotine  (10 genes)  IMP  
GO:0032098 [list] [network] regulation of appetite  (24 genes)  ISO ISS  
GO:0019934 [list] [network] cGMP-mediated signaling  (25 genes)  ISO  
GO:0051482 [list] [network] positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway  (39 genes)  ISO ISS  
GO:0098664 [list] [network] G protein-coupled serotonin receptor signaling pathway  (41 genes)  IEA ISO  
GO:0001662 [list] [network] behavioral fear response  (45 genes)  ISO ISS  
GO:0007187 [list] [network] G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  (48 genes)  IBA TAS  
GO:0051209 [list] [network] release of sequestered calcium ion into cytosol  (48 genes)  IBA ISO  
GO:0045907 [list] [network] positive regulation of vasoconstriction  (55 genes)  IMP  
GO:0051930 [list] [network] regulation of sensory perception of pain  (59 genes)  IMP  
GO:0045600 [list] [network] positive regulation of fat cell differentiation  (73 genes)  ISO  
GO:0007200 [list] [network] phospholipase C-activating G protein-coupled receptor signaling pathway  (95 genes)  IBA  
GO:0007631 [list] [network] feeding behavior  (108 genes)  IEA IMP ISO  
GO:0031100 [list] [network] animal organ regeneration  (161 genes)  IEP  
GO:0031644 [list] [network] regulation of nervous system process  (192 genes)  ISO ISS  
GO:0070374 [list] [network] positive regulation of ERK1 and ERK2 cascade  (232 genes)  ISO  
GO:0007626 [list] [network] locomotory behavior  (250 genes)  IEA  
GO:0040013 [list] [network] negative regulation of locomotion  (346 genes)  IMP  
GO:0007268 [list] [network] chemical synaptic transmission  (369 genes)  IBA  
GO:0006874 [list] [network] cellular calcium ion homeostasis  (481 genes)  ISO  
GO:0042493 [list] [network] response to drug  (643 genes)  IBA IMP  
GO CC
GO:0098666 [list] [network] G protein-coupled serotonin receptor complex  (4 genes)  ISO  
GO:0030425 [list] [network] dendrite  (800 genes)  IBA  
GO:0009986 [list] [network] cell surface  (937 genes)  IDA  
GO:0005887 [list] [network] integral component of plasma membrane  (1281 genes)  IBA IEA ISO ISS  
GO:0045202 [list] [network] synapse  (1547 genes)  IEA  
GO:0005886 [list] [network] plasma membrane  (5814 genes)  ISO  
GO MF
GO:0071886 [list] [network] 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding  (2 genes)  ISO  
GO:0001587 [list] [network] Gq/11-coupled serotonin receptor activity  (3 genes)  ISO ISS  
GO:0051378 [list] [network] serotonin binding  (13 genes)  ISO  
GO:0004993 [list] [network] G protein-coupled serotonin receptor activity  (40 genes)  IBA IEA IMP ISO  
GO:0030594 [list] [network] neurotransmitter receptor activity  (110 genes)  IBA  
GO:0042802 [list] [network] identical protein binding  (2232 genes)  ISO  
GO:0005515 [list] [network] protein binding  (7349 genes)  IPI  
KEGG rno04020 [list] [network] Calcium signaling pathway (238 genes)
rno04080 [list] [network] Neuroactive ligand-receptor interaction (375 genes)
rno04540 [list] [network] Gap junction (87 genes)
rno04726 [list] [network] Serotonergic synapse (123 genes)
rno04750 [list] [network] Inflammatory mediator regulation of TRP channels (115 genes)
Protein NP_036897.2  XP_038955425.1 
BLAST NP_036897.2  XP_038955425.1 
Orthologous [Ortholog page] HTR2A (hsa)  HTR2B (hsa)  HTR2C (hsa)  Htr2a (mmu)  Htr2b (mmu)  Htr2c (mmu)  Htr2b (rno)  Htr2a (rno)  5-HT2A (dme)  5-HT2B (dme)  ser-1 (cel)  HTR2B (gga)  HTR2B (cfa)  HTR2A (cfa)  HTR2A (gga)  HTR2C (gga)  HTR2C (cfa)  htr2ab (dre)  htr2aa (dre)  HTR2A (mcc)  HTR2C (mcc)  HTR2B (mcc)  htr2b (dre)  htr2cl2 (dre)  dic1 (spo)  htr2cl1 (dre)  HTR2A (fca)  HTR2B (fca)  HTR2C (fca) 
Subcellular
localization
wolf
plas 10  (predict for NP_036897.2)
plas 8,  pero 1  (predict for XP_038955425.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno04080 Neuroactive ligand-receptor interaction 10
rno04727 GABAergic synapse 4
rno04723 Retrograde endocannabinoid signaling 3
rno04020 Calcium signaling pathway 3
rno04540 Gap junction 3
Genes directly connected with Htr2c on the network
coex z* Locus Function* Coexpression
detail		 Entrez Gene ID*
7.6 Trhr thyrotropin releasing hormone receptor [detail] 25570
7.1 Glra2 glycine receptor, alpha 2 [detail] 24397
6.4 Gad2 glutamate decarboxylase 2 [detail] 24380
6.2 Tac1 tachykinin, precursor 1 [detail] 24806
5.0 Slc24a4 solute carrier family 24 member 4 [detail] 314396
4.6 Igfbpl1 insulin-like growth factor binding protein-like 1 [detail] 366366
Coexpressed
gene list		 [Coexpressed gene list for Htr2c]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 25187      
Refseq ID (protein) NP_036897.2 
XP_038955425.1 


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