[←][→] mmu  Htr2c Gene
functional annotation
Function   5-hydroxytryptamine (serotonin) receptor 2C  
GO BP
GO:0031583 [list] [network] phospholipase D-activating G protein-coupled receptor signaling pathway  (2 genes)  ISO  
GO:0007208 [list] [network] phospholipase C-activating serotonin receptor signaling pathway  (3 genes)  IMP ISO  
GO:0010513 [list] [network] positive regulation of phosphatidylinositol biosynthetic process  (3 genes)  ISO  
GO:0014057 [list] [network] positive regulation of acetylcholine secretion, neurotransmission  (3 genes)  ISO  
GO:0045963 [list] [network] negative regulation of dopamine metabolic process  (4 genes)  ISO  
GO:0043397 [list] [network] regulation of corticotropin-releasing hormone secretion  (5 genes)  IMP  
GO:0014054 [list] [network] positive regulation of gamma-aminobutyric acid secretion  (7 genes)  ISO  
GO:0035095 [list] [network] behavioral response to nicotine  (10 genes)  ISO  
GO:0098664 [list] [network] G protein-coupled serotonin receptor signaling pathway  (12 genes)  ISO  
GO:0048016 [list] [network] inositol phosphate-mediated signaling  (19 genes)  ISO  
GO:0019934 [list] [network] cGMP-mediated signaling  (24 genes)  ISO  
GO:0032098 [list] [network] regulation of appetite  (24 genes)  IMP  
GO:0051482 [list] [network] positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway  (38 genes)  IMP  
GO:0051209 [list] [network] release of sequestered calcium ion into cytosol  (42 genes)  IBA ISO  
GO:0001662 [list] [network] behavioral fear response  (44 genes)  IMP  
GO:0007187 [list] [network] G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  (50 genes)  IBA  
GO:0045907 [list] [network] positive regulation of vasoconstriction  (53 genes)  ISO  
GO:0051930 [list] [network] regulation of sensory perception of pain  (57 genes)  ISO  
GO:0045600 [list] [network] positive regulation of fat cell differentiation  (70 genes)  IMP  
GO:0007200 [list] [network] phospholipase C-activating G protein-coupled receptor signaling pathway  (96 genes)  IBA  
GO:0007631 [list] [network] feeding behavior  (103 genes)  IMP ISO  
GO:0031644 [list] [network] regulation of nervous system process  (189 genes)  IMP  
GO:0070374 [list] [network] positive regulation of ERK1 and ERK2 cascade  (228 genes)  ISO  
GO:0042493 [list] [network] response to drug  (253 genes)  IBA ISO  
GO:0007626 [list] [network] locomotory behavior  (258 genes)  IEA  
GO:0040013 [list] [network] negative regulation of locomotion  (338 genes)  ISO  
GO:0007268 [list] [network] chemical synaptic transmission  (354 genes)  IBA  
GO:0006874 [list] [network] cellular calcium ion homeostasis  (466 genes)  ISO  
GO:0007610 [list] [network] behavior  (712 genes)  IEA  
GO:0007186 [list] [network] G protein-coupled receptor signaling pathway  (1829 genes)  IEA  
GO:0007165 [list] [network] signal transduction  (4968 genes)  IEA  
GO CC
GO:0098666 [list] [network] G protein-coupled serotonin receptor complex  (4 genes)  ISO  
GO:0009897 [list] [network] external side of plasma membrane  (621 genes)  ISO  
GO:0030425 [list] [network] dendrite  (740 genes)  IBA  
GO:0009986 [list] [network] cell surface  (1142 genes)  ISO  
GO:0005887 [list] [network] integral component of plasma membrane  (1555 genes)  IBA ISO  
GO:0005886 [list] [network] plasma membrane  (5442 genes)  ISO  
GO:0016021 [list] [network] integral component of membrane  (5954 genes)  IEA  
GO:0016020 [list] [network] membrane  (9571 genes)  IEA  
GO MF
GO:0071886 [list] [network] 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding  (2 genes)  ISO  
GO:0001587 [list] [network] Gq/11-coupled serotonin receptor activity  (3 genes)  ISO  
GO:0051378 [list] [network] serotonin binding  (14 genes)  ISO  
GO:0004993 [list] [network] G protein-coupled serotonin receptor activity  (40 genes)  IBA IMP ISO  
GO:0030594 [list] [network] neurotransmitter receptor activity  (110 genes)  IBA  
GO:0004930 [list] [network] G protein-coupled receptor activity  (759 genes)  IEA  
GO:0042802 [list] [network] identical protein binding  (2357 genes)  ISO  
KEGG mmu04020 [list] [network] Calcium signaling pathway (240 genes)
mmu04080 [list] [network] Neuroactive ligand-receptor interaction (376 genes)
mmu04540 [list] [network] Gap junction (86 genes)
mmu04726 [list] [network] Serotonergic synapse (131 genes)
mmu04750 [list] [network] Inflammatory mediator regulation of TRP channels (127 genes)
Protein NP_032338.3  XP_030107088.1 
BLAST NP_032338.3  XP_030107088.1 
Orthologous [Ortholog page] HTR2A (hsa)  HTR2B (hsa)  HTR2C (hsa)  Htr2a (mmu)  Htr2b (mmu)  Htr2c (rno)  Htr2b (rno)  Htr2a (rno)  5-HT2A (dme)  5-HT2B (dme)  ser-1 (cel)  HTR2B (gga)  HTR2B (cfa)  HTR2A (cfa)  HTR2A (gga)  HTR2C (gga)  HTR2C (cfa)  htr2ab (dre)  htr2aa (dre)  HTR2A (mcc)  HTR2C (mcc)  HTR2B (mcc)  htr2b (dre)  htr2cl2 (dre)  dic1 (spo)  htr2cl1 (dre)  HTR2A (fca)  HTR2B (fca)  HTR2C (fca) 
Subcellular
localization
wolf
plas 10  (predict for NP_032338.3)
plas 8,  pero 1  (predict for XP_030107088.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04080 Neuroactive ligand-receptor interaction 4
mmu04020 Calcium signaling pathway 2
Genes directly connected with Htr2c on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
11.8 Gpr101 G protein-coupled receptor 101 [detail] 0 245424
9.5 Glra2 glycine receptor, alpha 2 subunit [detail] 1 237213
9.4 Gm4988 predicted gene 4988 [detail] 0 245440
7.1 Tacr3 tachykinin receptor 3 [detail] 0 21338
7.0 Slc39a12 solute carrier family 39 (zinc transporter), member 12 [detail] 0 277468
6.5 Mrap2 melanocortin 2 receptor accessory protein 2 [detail] 0 244958
Coexpressed
gene list		 [Coexpressed gene list for Htr2c]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 15560      
Refseq ID (protein) NP_032338.3 
XP_030107088.1 


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