[←][→] mmu  Htr2b Gene
functional annotation
Function   5-hydroxytryptamine (serotonin) receptor 2B  
GO BP
GO:0071418 [list] [network] cellular response to amine stimulus  (1 genes)  ISO  
GO:1904015 [list] [network] cellular response to serotonin  (2 genes)  ISO  
GO:0007208 [list] [network] phospholipase C-activating serotonin receptor signaling pathway  (3 genes)  ISO TAS  
GO:0010513 [list] [network] positive regulation of phosphatidylinositol biosynthetic process  (3 genes)  ISO  
GO:0014827 [list] [network] intestine smooth muscle contraction  (4 genes)  ISO  
GO:0071502 [list] [network] cellular response to temperature stimulus  (4 genes)  IDA  
GO:0098664 [list] [network] G protein-coupled serotonin receptor signaling pathway  (12 genes)  ISO  
GO:0002031 [list] [network] G protein-coupled receptor internalization  (15 genes)  IDA  
GO:0070528 [list] [network] protein kinase C signaling  (17 genes)  ISO  
GO:0051000 [list] [network] positive regulation of nitric-oxide synthase activity  (20 genes)  ISO  
GO:0019934 [list] [network] cGMP-mediated signaling  (24 genes)  ISO  
GO:0007202 [list] [network] activation of phospholipase C activity  (25 genes)  ISO  
GO:0007205 [list] [network] protein kinase C-activating G protein-coupled receptor signaling pathway  (26 genes)  IMP  
GO:0070371 [list] [network] ERK1 and ERK2 cascade  (34 genes)  IMP ISO  
GO:0003300 [list] [network] cardiac muscle hypertrophy  (36 genes)  IMP  
GO:0014065 [list] [network] phosphatidylinositol 3-kinase signaling  (36 genes)  ISO  
GO:0042310 [list] [network] vasoconstriction  (38 genes)  ISO  
GO:0051209 [list] [network] release of sequestered calcium ion into cytosol  (42 genes)  IBA ISO  
GO:0007187 [list] [network] G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  (50 genes)  IBA  
GO:0006939 [list] [network] smooth muscle contraction  (55 genes)  IEA  
GO:0001755 [list] [network] neural crest cell migration  (58 genes)  IMP  
GO:0010507 [list] [network] negative regulation of autophagy  (72 genes)  ISO  
GO:0014033 [list] [network] neural crest cell differentiation  (94 genes)  IMP  
GO:0007200 [list] [network] phospholipase C-activating G protein-coupled receptor signaling pathway  (96 genes)  IBA  
GO:0051781 [list] [network] positive regulation of cell division  (97 genes)  IMP  
GO:0001938 [list] [network] positive regulation of endothelial cell proliferation  (98 genes)  IMP ISO  
GO:0050795 [list] [network] regulation of behavior  (98 genes)  IMP ISO  
GO:0043406 [list] [network] positive regulation of MAP kinase activity  (109 genes)  ISO  
GO:0019722 [list] [network] calcium-mediated signaling  (123 genes)  ISO  
GO:0070374 [list] [network] positive regulation of ERK1 and ERK2 cascade  (228 genes)  ISO  
GO:0042493 [list] [network] response to drug  (253 genes)  IBA ISO  
GO:0003007 [list] [network] heart morphogenesis  (278 genes)  IMP  
GO:0007268 [list] [network] chemical synaptic transmission  (354 genes)  IBA  
GO:0006874 [list] [network] cellular calcium ion homeostasis  (466 genes)  ISO  
GO:0001819 [list] [network] positive regulation of cytokine production  (501 genes)  IMP ISO  
GO:0007507 [list] [network] heart development  (585 genes)  IMP  
GO:0034220 [list] [network] ion transmembrane transport  (619 genes)  ISO  
GO:0048598 [list] [network] embryonic morphogenesis  (636 genes)  IMP  
GO:0007610 [list] [network] behavior  (712 genes)  IEA  
GO:0016310 [list] [network] phosphorylation  (836 genes)  ISO  
GO:0043066 [list] [network] negative regulation of apoptotic process  (968 genes)  IMP  
GO:0008284 [list] [network] positive regulation of cell population proliferation  (1011 genes)  ISO  
GO:0060548 [list] [network] negative regulation of cell death  (1116 genes)  ISO  
GO:0007186 [list] [network] G protein-coupled receptor signaling pathway  (1829 genes)  ISO  
GO:0007165 [list] [network] signal transduction  (4968 genes)  IEA  
GO CC
GO:0098666 [list] [network] G protein-coupled serotonin receptor complex  (4 genes)  IDA ISO  
GO:0043025 [list] [network] neuronal cell body  (722 genes)  ISO  
GO:0030425 [list] [network] dendrite  (740 genes)  IBA ISO  
GO:0043005 [list] [network] neuron projection  (1541 genes)  IEA  
GO:0005887 [list] [network] integral component of plasma membrane  (1555 genes)  IBA  
GO:0030054 [list] [network] cell junction  (2071 genes)  IEA  
GO:0005654 [list] [network] nucleoplasm  (3580 genes)  ISO  
GO:0005886 [list] [network] plasma membrane  (5442 genes)  IDA ISO  
GO:0016021 [list] [network] integral component of membrane  (5954 genes)  IEA  
GO:0016020 [list] [network] membrane  (9571 genes)  ISO  
GO:0005737 [list] [network] cytoplasm  (11434 genes)  IDA ISO  
GO MF
GO:0001587 [list] [network] Gq/11-coupled serotonin receptor activity  (3 genes)  ISO  
GO:0051378 [list] [network] serotonin binding  (14 genes)  IDA ISO  
GO:0001965 [list] [network] G-protein alpha-subunit binding  (40 genes)  ISO  
GO:0004993 [list] [network] G protein-coupled serotonin receptor activity  (40 genes)  IBA IDA ISO TAS  
GO:0030594 [list] [network] neurotransmitter receptor activity  (110 genes)  IBA  
GO:0005096 [list] [network] GTPase activator activity  (406 genes)  IMP  
GO:0004930 [list] [network] G protein-coupled receptor activity  (759 genes)  IEA  
KEGG mmu04020 [list] [network] Calcium signaling pathway (240 genes)
mmu04080 [list] [network] Neuroactive ligand-receptor interaction (376 genes)
mmu04540 [list] [network] Gap junction (86 genes)
mmu04726 [list] [network] Serotonergic synapse (131 genes)
mmu04750 [list] [network] Inflammatory mediator regulation of TRP channels (127 genes)
Protein NP_032337.2  XP_006529209.1  XP_030105897.1 
BLAST NP_032337.2  XP_006529209.1  XP_030105897.1 
Orthologous [Ortholog page] HTR2A (hsa)  HTR2B (hsa)  HTR2C (hsa)  Htr2a (mmu)  Htr2c (mmu)  Htr2c (rno)  Htr2b (rno)  Htr2a (rno)  5-HT2A (dme)  5-HT2B (dme)  ser-1 (cel)  HTR2B (gga)  HTR2B (cfa)  HTR2A (cfa)  HTR2A (gga)  HTR2C (gga)  HTR2C (cfa)  htr2ab (dre)  htr2aa (dre)  HTR2A (mcc)  HTR2C (mcc)  HTR2B (mcc)  htr2b (dre)  htr2cl2 (dre)  dic1 (spo)  htr2cl1 (dre)  HTR2A (fca)  HTR2B (fca)  HTR2C (fca) 
Subcellular
localization
wolf
plas 10  (predict for NP_032337.2)
plas 10  (predict for XP_006529209.1)
plas 8,  pero 1  (predict for XP_030105897.1)
Gene coexpression
Network*for
coexpressed
genes
Coexpressed
gene list		 [Coexpressed gene list for Htr2b]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 15559      
Refseq ID (protein) NP_032337.2 
XP_006529209.1 
XP_030105897.1 


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