| functional annotation |
| Function |
succinate dehydrogenase complex iron sulfur subunit B |
|
| GO BP |
|
GO:0006105 [list] [network] succinate metabolic process
|
(6 genes)
|
IEA
|
 |
|
GO:0006099 [list] [network] tricarboxylic acid cycle
|
(34 genes)
|
IEA
TAS
|
|
|
GO:0022904 [list] [network] respiratory electron transport chain
|
(113 genes)
|
IBA
|
|
|
GO:0009060 [list] [network] aerobic respiration
|
(162 genes)
|
IBA
|
|
|
| GO CC |
|
GO:0005749 [list] [network] mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)
|
(4 genes)
|
ISS
|
|
|
GO:0005743 [list] [network] mitochondrial inner membrane
|
(494 genes)
|
ISS
TAS
|
|
|
GO:0031966 [list] [network] mitochondrial membrane
|
(730 genes)
|
IBA
|
|
|
GO:0005739 [list] [network] mitochondrion
|
(1648 genes)
|
IDA
|
|
|
GO:0005654 [list] [network] nucleoplasm
|
(4086 genes)
|
IDA
|
|
|
GO:0005886 [list] [network] plasma membrane
|
(5772 genes)
|
IDA
|
|
|
| GO MF |
|
GO:0008177 [list] [network] succinate dehydrogenase (ubiquinone) activity
|
(2 genes)
|
IEA
|
|
|
GO:0051538 [list] [network] 3 iron, 4 sulfur cluster binding
|
(3 genes)
|
ISS
|
|
|
GO:0048039 [list] [network] ubiquinone binding
|
(7 genes)
|
ISS
|
|
|
GO:0051537 [list] [network] 2 iron, 2 sulfur cluster binding
|
(22 genes)
|
ISS
|
|
|
GO:0051539 [list] [network] 4 iron, 4 sulfur cluster binding
|
(42 genes)
|
ISS
|
|
|
GO:0009055 [list] [network] electron transfer activity
|
(123 genes)
|
IEA
|
|
|
GO:0046872 [list] [network] metal ion binding
|
(4237 genes)
|
IEA
|
|
|
GO:0005515 [list] [network] protein binding
|
(13898 genes)
|
IPI
|
|
|
| KEGG |
hsa00020 [list] [network] Citrate cycle (TCA cycle) (30 genes) |
 |
| hsa00190 [list] [network] Oxidative phosphorylation (134 genes) |
|
| hsa01200 [list] [network] Carbon metabolism (115 genes) |
|
| hsa04714 [list] [network] Thermogenesis (232 genes) |
|
| hsa04932 [list] [network] Non-alcoholic fatty liver disease (155 genes) |
|
| hsa05010 [list] [network] Alzheimer disease (384 genes) |
|
| hsa05012 [list] [network] Parkinson disease (266 genes) |
|
| hsa05014 [list] [network] Amyotrophic lateral sclerosis (364 genes) |
|
| hsa05016 [list] [network] Huntington disease (306 genes) |
|
| hsa05020 [list] [network] Prion disease (273 genes) |
|
| hsa05022 [list] [network] Pathways of neurodegeneration - multiple diseases (476 genes) |
|
| hsa05208 [list] [network] Chemical carcinogenesis - reactive oxygen species (223 genes) |
|
| hsa05415 [list] [network] Diabetic cardiomyopathy (203 genes) |
|
| Protein |
NP_002991.2
|
| BLAST |
NP_002991.2
|
| Orthologous |
[Ortholog page]
SdhB (dme)
Sdhb (mmu)
sdhb-1 (cel)
Sdhb (rno)
SDHB (cfa)
sdhb (dre)
SDHB (mcc)
SDHB (fca)
SDH2 (sce)
SPCC622.11 (spo)
SDHB (gga)
|
Subcellular
localization
wolf |
|
mito 8,
cyto 1,
extr 1,
nucl 1
|
(predict for NP_002991.2)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| hsa05012 |
Parkinson disease |
12 |
 |
| hsa05022 |
Pathways of neurodegeneration - multiple diseases |
12 |
 |
| hsa00190 |
Oxidative phosphorylation |
11 |
 |
| hsa04714 |
Thermogenesis |
11 |
 |
| hsa05010 |
Alzheimer disease |
11 |
 |
Genes directly connected with SDHB on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
CoexPub |
Entrez Gene ID* |
| 11.2 |
ATP5PB |
ATP synthase peripheral stalk-membrane subunit b |
[detail] |
6 |
515 |
| 10.2 |
UQCRFS1 |
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 |
[detail] |
15 |
7386 |
| 10.1 |
SUCLG1 |
succinate-CoA ligase GDP/ADP-forming subunit alpha |
[detail] |
10 |
8802 |
| 9.6 |
MRPS15 |
mitochondrial ribosomal protein S15 |
[detail] |
0 |
64960 |
| 7.9 |
MFN2 |
mitofusin 2 |
[detail] |
3 |
9927 |
| 7.1 |
MRPL37 |
mitochondrial ribosomal protein L37 |
[detail] |
0 |
51253 |
| 6.8 |
MRPL16 |
mitochondrial ribosomal protein L16 |
[detail] |
0 |
54948 |
| 6.7 |
ATG3 |
autophagy related 3 |
[detail] |
0 |
64422 |
|
Coexpressed
gene list |
[Coexpressed gene list for SDHB]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
SDHB Gene
