| Representative coexpressed gene network |

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| hsa01200 |
Carbon metabolism |
22 |
 |
| hsa00020 |
Citrate cycle (TCA cycle) |
21 |
 |
| hsa05415 |
Diabetic cardiomyopathy |
12 |
 |
| hsa00190 |
Oxidative phosphorylation |
10 |
 |
| hsa04714 |
Thermogenesis |
10 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| mmu00020 |
Citrate cycle (TCA cycle) |
24 |
 |
| mmu01200 |
Carbon metabolism |
24 |
 |
| mmu05415 |
Diabetic cardiomyopathy |
12 |
 |
| mmu00190 |
Oxidative phosphorylation |
10 |
 |
| mmu04714 |
Thermogenesis |
10 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| rno01200 |
Carbon metabolism |
24 |
 |
| rno00020 |
Citrate cycle (TCA cycle) |
23 |
 |
| rno05415 |
Diabetic cardiomyopathy |
15 |
 |
| rno05012 |
Parkinson disease |
14 |
 |
| rno05022 |
Pathways of neurodegeneration - multiple diseases |
14 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| gga01200 |
Carbon metabolism |
23 |
 |
| gga00020 |
Citrate cycle (TCA cycle) |
22 |
 |
| gga00190 |
Oxidative phosphorylation |
14 |
 |
| gga01210 |
2-Oxocarboxylic acid metabolism |
8 |
 |
| gga01230 |
Biosynthesis of amino acids |
8 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| dre00020 |
Citrate cycle (TCA cycle) |
27 |
 |
| dre01200 |
Carbon metabolism |
27 |
 |
| dre00190 |
Oxidative phosphorylation |
12 |
 |
| dre00620 |
Pyruvate metabolism |
11 |
 |
| dre01230 |
Biosynthesis of amino acids |
10 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| dme00020 |
Citrate cycle (TCA cycle) |
31 |
 |
| dme01200 |
Carbon metabolism |
31 |
 |
| dme00620 |
Pyruvate metabolism |
12 |
 |
| dme01230 |
Biosynthesis of amino acids |
11 |
 |
| dme01210 |
2-Oxocarboxylic acid metabolism |
10 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| cel01200 |
Carbon metabolism |
30 |
 |
| cel00020 |
Citrate cycle (TCA cycle) |
28 |
 |
| cel01230 |
Biosynthesis of amino acids |
13 |
 |
| cel00620 |
Pyruvate metabolism |
11 |
 |
| cel00010 |
Glycolysis / Gluconeogenesis |
9 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| mcc00020 |
Citrate cycle (TCA cycle) |
19 |
 |
| mcc01200 |
Carbon metabolism |
19 |
 |
| mcc05415 |
Diabetic cardiomyopathy |
11 |
 |
| mcc00190 |
Oxidative phosphorylation |
9 |
 |
| mcc04714 |
Thermogenesis |
9 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| cfa01200 |
Carbon metabolism |
20 |
 |
| cfa00020 |
Citrate cycle (TCA cycle) |
19 |
 |
| cfa00620 |
Pyruvate metabolism |
9 |
 |
| cfa05415 |
Diabetic cardiomyopathy |
7 |
 |
| cfa00630 |
Glyoxylate and dicarboxylate metabolism |
7 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| sce01200 |
Carbon metabolism |
29 |
 |
| sce00020 |
Citrate cycle (TCA cycle) |
26 |
 |
| sce00620 |
Pyruvate metabolism |
10 |
 |
| sce01230 |
Biosynthesis of amino acids |
9 |
 |
| sce00630 |
Glyoxylate and dicarboxylate metabolism |
8 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| spo00020 |
Citrate cycle (TCA cycle) |
22 |
 |
| spo01200 |
Carbon metabolism |
21 |
 |
| spo00620 |
Pyruvate metabolism |
8 |
 |
| spo01230 |
Biosynthesis of amino acids |
7 |
 |
| spo01210 |
2-Oxocarboxylic acid metabolism |
6 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| fca01200 |
Carbon metabolism |
23 |
 |
| fca00020 |
Citrate cycle (TCA cycle) |
20 |
 |
| fca05415 |
Diabetic cardiomyopathy |
13 |
 |
| fca05010 |
Alzheimer disease |
11 |
 |
| fca05012 |
Parkinson disease |
11 |
 |
|
| Gene list in the network |
|
|
Symbol |
Function* |
| |
Aco1 |
aconitase 1 |
| |
Aco2 |
aconitase 2, mitochondrial |
| |
Atp5a1 |
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 |
| |
Cs |
citrate synthase |
| |
Dld |
dihydrolipoamide dehydrogenase |
| |
Fh1 |
fumarate hydratase 1 |
| |
Hadh |
hydroxyacyl-Coenzyme A dehydrogenase |
| |
Idh1 |
isocitrate dehydrogenase 1 (NADP+), soluble |
| |
Idh3g |
isocitrate dehydrogenase 3 (NAD+), gamma |
| |
Mdh2 |
malate dehydrogenase 2, NAD (mitochondrial) |
| |
Mdh1 |
malate dehydrogenase 1, NAD (soluble) |
| |
Ndufv1 |
NADH:ubiquinone oxidoreductase core subunit V1 |
| |
Nnt |
nicotinamide nucleotide transhydrogenase |
| |
Ogdh |
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| |
Pdha1 |
pyruvate dehydrogenase E1 alpha 1 |
| |
Sucla2 |
succinate-Coenzyme A ligase, ADP-forming, beta subunit |
| |
Suclg2 |
succinate-Coenzyme A ligase, GDP-forming, beta subunit |
| |
Pdhx |
pyruvate dehydrogenase complex, component X |
| |
Suclg1 |
succinate-CoA ligase, GDP-forming, alpha subunit |
| |
Sdhc |
succinate dehydrogenase complex, subunit C, integral membrane protein |
| |
Ndufa9 |
NADH:ubiquinone oxidoreductase subunit A9 |
| |
Sdhd |
succinate dehydrogenase complex, subunit D, integral membrane protein |
| |
Sdha |
succinate dehydrogenase complex, subunit A, flavoprotein (Fp) |
| |
Uqcrc2 |
ubiquinol cytochrome c reductase core protein 2 |
| |
Sdhb |
succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| |
Idh3a |
isocitrate dehydrogenase 3 (NAD+) alpha |
| |
Mtfp1 |
mitochondrial fission process 1 |
| |
Coq9 |
coenzyme Q9 |
| |
Pdhb |
pyruvate dehydrogenase (lipoamide) beta |
| |
Dlst |
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) |
| |
Idh3b |
isocitrate dehydrogenase 3 (NAD+) beta |
| |
Ndufs2 |
NADH:ubiquinone oxidoreductase core subunit S2 |
| |
Ndufs1 |
NADH:ubiquinone oxidoreductase core subunit S1 |
| |
Dlat |
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) |
| |
Idh2 |
isocitrate dehydrogenase 2 (NADP+), mitochondrial |
|
|
|
Symbol |
Function* |
| |
ACO1 |
aconitase 1, soluble |
| |
ACO2 |
aconitase 2 |
| |
SOD2 |
superoxide dismutase 2, mitochondrial |
| |
SDHA |
succinate dehydrogenase complex flavoprotein subunit A |
| |
GOT1 |
glutamic-oxaloacetic transaminase 1 |
| |
IDH3A |
isocitrate dehydrogenase 3 (NAD(+)) alpha |
| |
UQCRFS1 |
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 |
| |
UQCRC1 |
ubiquinol-cytochrome c reductase core protein 1 |
| |
PDHB |
pyruvate dehydrogenase (lipoamide) beta |
| |
ISCU |
iron-sulfur cluster assembly enzyme |
| |
COX10 |
COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor |
| |
MDH2 |
malate dehydrogenase 2 |
| |
DLD |
dihydrolipoamide dehydrogenase |
| |
PDHA2 |
pyruvate dehydrogenase (lipoamide) alpha 2 |
| |
SUCLA2 |
succinate-CoA ligase ADP-forming beta subunit |
| |
NDUFA9 |
NADH:ubiquinone oxidoreductase subunit A9 |
| |
ATP5C1 |
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 |
| |
NFS1 |
NFS1, cysteine desulfurase |
| |
SDHD |
succinate dehydrogenase complex subunit D |
| |
DLAT |
dihydrolipoamide S-acetyltransferase |
| |
CYCS |
cytochrome c, somatic |
| |
FH |
fumarate hydratase |
| |
MDH1 |
malate dehydrogenase 1 |
| |
SUCLG1 |
succinate-CoA ligase alpha subunit |
| |
DLST |
dihydrolipoamide S-succinyltransferase |
| |
NDUFS1 |
NADH:ubiquinone oxidoreductase core subunit S1 |
| |
IDH1 |
isocitrate dehydrogenase (NADP(+)) 1, cytosolic |
| |
OGDH |
oxoglutarate dehydrogenase |
| |
IDH3B |
isocitrate dehydrogenase 3 (NAD(+)) beta |
| |
ATP5B |
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide |
| |
PROSC |
proline synthetase cotranscribed homolog (bacterial) |
| |
UQCRC2 |
ubiquinol-cytochrome c reductase core protein II |
| |
IDH2 |
isocitrate dehydrogenase (NADP(+)) 2, mitochondrial |
| |
COQ10A |
coenzyme Q10A |
| |
NDUFS2 |
NADH:ubiquinone oxidoreductase core subunit S2 |
| |
CS |
citrate synthase |
| |
SDHC |
succinate dehydrogenase complex subunit C |
| |
SDHB |
succinate dehydrogenase complex iron sulfur subunit B |
| |
LOC107050579 |
NAD-dependent malic enzyme, mitochondrial-like |
|
|
Symbol |
Function* |
| |
ldhba |
lactate dehydrogenase Ba |
| |
suclg2 |
succinate-CoA ligase GDP-forming subunit beta |
| |
cs |
citrate synthase |
| |
uqcrc2b |
ubiquinol-cytochrome c reductase core protein 2b |
| |
aco2 |
aconitase 2, mitochondrial |
| |
dlat |
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) |
| |
immt |
inner membrane protein, mitochondrial (mitofilin) |
| |
vdac1 |
voltage-dependent anion channel 1 |
| |
mdh1ab |
malate dehydrogenase 1Ab, NAD (soluble) |
| |
slc25a12 |
solute carrier family 25 member 12 |
| |
dlst |
dihydrolipoamide S-succinyltransferase |
| |
glud1b |
glutamate dehydrogenase 1b |
| |
idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
| |
uqcrc1 |
ubiquinol-cytochrome c reductase core protein 1 |
| |
sdha |
succinate dehydrogenase complex, subunit A, flavoprotein (Fp) |
| |
idh3a |
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha |
| |
fh |
fumarate hydratase |
| |
dldh |
dihydrolipoamide dehydrogenase |
| |
mdh1aa |
malate dehydrogenase 1Aa, NAD (soluble) |
| |
sucla2 |
succinate-CoA ligase ADP-forming subunit beta |
| |
got1 |
glutamic-oxaloacetic transaminase 1, soluble |
| |
mdh2 |
malate dehydrogenase 2, NAD (mitochondrial) |
| |
pdhb |
pyruvate dehydrogenase E1 subunit beta |
| |
slc37a4a |
solute carrier family 37 member 4a |
| |
pck2 |
phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| |
vdac3 |
voltage-dependent anion channel 3 |
| |
nnt |
nicotinamide nucleotide transhydrogenase |
| |
msmo1 |
methylsterol monooxygenase 1 |
| |
pdha1a |
pyruvate dehydrogenase E1 subunit alpha 1a |
| |
chchd3a |
coiled-coil-helix-coiled-coil-helix domain containing 3a |
| |
slc25a11 |
solute carrier family 25 member 11 |
| |
idh3b |
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta |
| |
suclg1 |
succinate-CoA ligase GDP/ADP-forming subunit alph |
| |
aclya |
ATP citrate lyase a |
| |
dnajc15 |
DnaJ (Hsp40) homolog, subfamily C, member 15 |
| |
ndufv1 |
NADH:ubiquinone oxidoreductase core subunit V1 |
| |
sdhdb |
succinate dehydrogenase complex, subunit D, integral membrane protein b |
| |
ndufs1 |
NADH:ubiquinone oxidoreductase core subunit S1 |
| |
ndufa9a |
NADH:ubiquinone oxidoreductase subunit A9a |
| |
idh3g |
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma |
| |
pcxa |
pyruvate carboxylase a |
| |
ndufs2 |
NADH:ubiquinone oxidoreductase core subunit S2 |
| |
atp5fa1 |
ATP synthase F1 subunit alpha |
| |
atp5f1b |
ATP synthase F1 subunit beta |
| |
sdhb |
succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| |
cyc1 |
cytochrome c-1 |
| |
ogdha |
oxoglutarate dehydrogenase a |
| |
coq9 |
coenzyme Q9 homolog (S. cerevisiae) |
| |
aco1 |
aconitase 1, soluble |
| |
gusb |
glucuronidase, beta |
| |
clybl |
citrate lyase beta like |
| |
idh1 |
isocitrate dehydrogenase (NADP(+)) 1 |
|
|
|
Symbol |
Function* |
| |
W10C8.5 |
Arginine kinase |
| |
pgk-1 |
putative phosphoglycerate kinase |
| |
idhg-2 |
Isocitrate dehydrogenase [NAD] subunit, mitochondrial |
| |
pck-2 |
Phosphoenolpyruvate carboxykinase (GTP) |
| |
cyc-1 |
Cytochrome c domain-containing protein |
| |
idha-1 |
putative isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial |
| |
atp-1 |
ATP synthase subunit alpha, mitochondrial |
| |
acer-1 |
Acetyl-CoA deacylase |
| |
enol-1 |
Enolase |
| |
sdhb-1 |
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial |
| |
sdhd-1 |
Putative succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial |
| |
men-1 |
Malic enzyme |
| |
pck-1 |
Phosphoenolpyruvate carboxykinase (GTP) |
| |
idhg-1 |
Isocitrate dehydrogenase [NAD] subunit, mitochondrial |
| |
ucr-1 |
Cytochrome b-c1 complex subunit 1, mitochondrial;Peptidase_M16_C domain-containing protein |
| |
mdh-2 |
putative malate dehydrogenase, mitochondrial |
| |
fum-1 |
putative fumarate hydratase, mitochondrial |
| |
aco-2 |
putative aconitate hydratase, mitochondrial |
| |
cts-1 |
putative citrate synthase, mitochondrial |
| |
pdhb-1 |
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial |
| |
ogdh-1 |
2-oxoglutarate dehydrogenase, mitochondrial;Transket_pyr domain-containing protein |
| |
vdac-1 |
putative voltage-dependent anion-selective channel |
| |
isp-1 |
Cytochrome b-c1 complex subunit Rieske, mitochondrial |
| |
idh-1 |
Isocitrate dehydrogenase [NADP] |
| |
F01G4.6 |
Phosphate carrier protein, mitochondrial |
| |
dld-1 |
Dihydrolipoyl dehydrogenase, mitochondrial |
| |
ldp-1 |
Lipid droplet localized protein |
| |
mdh-1 |
Malate dehydrogenase |
| |
dlst-1 |
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial |
| |
pyc-1 |
Pyruvate carboxylase 1 |
| |
dlat-1 |
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial |
| |
acly-1 |
putative ATP-citrate synthase |
| |
immt-1 |
MICOS complex subunit MIC60-1 |
| |
gpd-3 |
Glyceraldehyde-3-phosphate dehydrogenase 3 |
| |
pcca-1 |
Propionyl-CoA carboxylase alpha chain, mitochondrial |
| |
sdha-1 |
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial |
| |
suca-1 |
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial |
| |
idh-2 |
Isocitrate dehydrogenase [NADP] |
| |
aco-1 |
putative cytoplasmic aconitate hydratase |
| |
idhb-1 |
putative isocitrate dehydrogenase [NAD] subunit beta, mitochondrial |
| |
sucl-1 |
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial |
| |
ucr-2.2 |
Peptidase_M16 domain-containing protein |
| |
mev-1 |
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial |
| |
pdha-1 |
Pyruvate dehydrogenase E1 component subunit alpha;putative pyruvate dehydrogenase E1 component subunit alpha, mitochondrial |
|
|
|
|
|
|