[←][→] mmu  Gucy1a1 Gene
functional annotation
Function   guanylate cyclase 1, soluble, alpha 1  
GO BP
GO:0098925 [list] [network] retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission  (1 genes)  IDA IMP  
GO:0010750 [list] [network] positive regulation of nitric oxide mediated signal transduction  (3 genes)  IMP  
GO:0060087 [list] [network] relaxation of vascular associated smooth muscle  (8 genes)  IMP  
GO:0006182 [list] [network] cGMP biosynthetic process  (12 genes)  IMP ISO  
GO:0009190 [list] [network] cyclic nucleotide biosynthetic process  (24 genes)  IEA  
GO:0008217 [list] [network] regulation of blood pressure  (213 genes)  IMP  
GO:0035556 [list] [network] intracellular signal transduction  (1356 genes)  IEA  
GO CC
GO:0008074 [list] [network] guanylate cyclase complex, soluble  (2 genes)  ISO  
GO:0098982 [list] [network] GABA-ergic synapse  (109 genes)  IDA IMP  
GO:0098978 [list] [network] glutamatergic synapse  (518 genes)  IDA IMP  
GO:0032991 [list] [network] protein-containing complex  (5540 genes)  ISO  
GO:0005737 [list] [network] cytoplasm  (11434 genes)  IEA  
GO MF
GO:0047805 [list] [network] cytidylate cyclase activity  (2 genes)  ISO  
GO:0004383 [list] [network] guanylate cyclase activity  (11 genes)  ISO  
GO:0004016 [list] [network] adenylate cyclase activity  (12 genes)  ISO  
GO:0016849 [list] [network] phosphorus-oxygen lyase activity  (25 genes)  IEA  
GO:0020037 [list] [network] heme binding  (162 genes)  IEA  
GO:0016829 [list] [network] lyase activity  (196 genes)  IEA  
GO:0005525 [list] [network] GTP binding  (358 genes)  IEA  
GO:0044877 [list] [network] protein-containing complex binding  (1549 genes)  ISO  
GO:0000166 [list] [network] nucleotide binding  (2052 genes)  IEA  
GO:0043167 [list] [network] ion binding  (5288 genes)  ISO  
KEGG mmu00230 [list] [network] Purine metabolism (133 genes)
mmu04022 [list] [network] cGMP-PKG signaling pathway (173 genes)
mmu04270 [list] [network] Vascular smooth muscle contraction (144 genes)
mmu04540 [list] [network] Gap junction (86 genes)
mmu04611 [list] [network] Platelet activation (124 genes)
mmu04713 [list] [network] Circadian entrainment (98 genes)
mmu04730 [list] [network] Long-term depression (60 genes)
mmu04921 [list] [network] Oxytocin signaling pathway (153 genes)
mmu04924 [list] [network] Renin secretion (76 genes)
mmu04970 [list] [network] Salivary secretion (86 genes)
Protein NP_001343916.1  NP_001343917.1  NP_068696.2 
BLAST NP_001343916.1  NP_001343917.1  NP_068696.2 
Orthologous [Ortholog page] GUCY1A1 (hsa)  GUCY1A3 (gga)  GUCY1A1 (cfa)  Gucy1a1 (rno)  gucy1a1 (dre)  GUCY1A1 (mcc)  GUCY1A1 (fca) 
Subcellular
localization
wolf
cyto 7,  cyto_nucl 4,  mito 2,  nucl 1,  E.R._mito 1,  mito_pero 1  (predict for NP_001343916.1)
cyto 7,  cyto_nucl 4,  mito 2,  nucl 1,  E.R._mito 1,  mito_pero 1  (predict for NP_001343917.1)
cyto 7,  cyto_nucl 4,  mito 2,  nucl 1,  E.R._mito 1,  mito_pero 1  (predict for NP_068696.2)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04022 cGMP-PKG signaling pathway 7
mmu00230 Purine metabolism 5
mmu04270 Vascular smooth muscle contraction 5
mmu04924 Renin secretion 5
mmu04540 Gap junction 4
Genes directly connected with Gucy1a1 on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
27.3 Gucy1b1 guanylate cyclase 1, soluble, beta 1 [detail] 13 54195
6.7 Tcf21 transcription factor 21 [detail] 0 21412
6.6 Pde3a phosphodiesterase 3A, cGMP inhibited [detail] 0 54611
4.2 Dach1 dachshund family transcription factor 1 [detail] 0 13134
3.9 Cd200 CD200 antigen [detail] 0 17470
Coexpressed
gene list		 [Coexpressed gene list for Gucy1a1]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 60596      
Refseq ID (protein) NP_001343916.1 
NP_001343917.1 
NP_068696.2 


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