[←][→] hsa  GUCY1A1 Gene
functional annotation
Function   guanylate cyclase 1 soluble subunit alpha 1  
GO BP
GO:0098925 [list] [network] retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission  (1 genes)  IEA  
GO:0010750 [list] [network] positive regulation of nitric oxide mediated signal transduction  (5 genes)  IEA  
GO:0060087 [list] [network] relaxation of vascular associated smooth muscle  (7 genes)  IEA  
GO:0006182 [list] [network] cGMP biosynthetic process  (11 genes)  IDA  
GO:0007263 [list] [network] nitric oxide mediated signal transduction  (20 genes)  TAS  
GO:0008217 [list] [network] regulation of blood pressure  (188 genes)  IEA  
GO:0008015 [list] [network] blood circulation  (394 genes)  TAS  
GO CC
GO:0008074 [list] [network] guanylate cyclase complex, soluble  (2 genes)  IDA  
GO:0098982 [list] [network] GABA-ergic synapse  (69 genes)  IEA  
GO:0098978 [list] [network] glutamatergic synapse  (338 genes)  IEA  
GO MF
GO:0004383 [list] [network] guanylate cyclase activity  (8 genes)  IDA  
GO:0020037 [list] [network] heme binding  (139 genes)  IEA  
GO:0005525 [list] [network] GTP binding  (378 genes)  IEA  
GO:0038023 [list] [network] signaling receptor activity  (1591 genes)  TAS  
GO:0005515 [list] [network] protein binding  (13898 genes)  IPI  
KEGG hsa00230 [list] [network] Purine metabolism (126 genes)
hsa04022 [list] [network] cGMP-PKG signaling pathway (167 genes)
hsa04270 [list] [network] Vascular smooth muscle contraction (134 genes)
hsa04540 [list] [network] Gap junction (88 genes)
hsa04611 [list] [network] Platelet activation (124 genes)
hsa04713 [list] [network] Circadian entrainment (97 genes)
hsa04730 [list] [network] Long-term depression (60 genes)
hsa04921 [list] [network] Oxytocin signaling pathway (154 genes)
hsa04924 [list] [network] Renin secretion (69 genes)
hsa04970 [list] [network] Salivary secretion (93 genes)
Protein NP_000847.2  NP_001124154.1  NP_001124155.1  NP_001124156.1  NP_001124157.1  NP_001124159.1  NP_001243378.1  NP_001366595.1  NP_001366596.1  NP_001366597.1  NP_001366598.1  NP_001366599.1  NP_001366600.1  NP_001366601.1  NP_001366602.1  NP_001366603.1  NP_001366604.1  NP_001366605.1  XP_005263013.1  XP_005263014.1  XP_011530202.1 
BLAST NP_000847.2  NP_001124154.1  NP_001124155.1  NP_001124156.1  NP_001124157.1  NP_001124159.1  NP_001243378.1  NP_001366595.1  NP_001366596.1  NP_001366597.1  NP_001366598.1  NP_001366599.1  NP_001366600.1  NP_001366601.1  NP_001366602.1  NP_001366603.1  NP_001366604.1  NP_001366605.1  XP_005263013.1  XP_005263014.1  XP_011530202.1 
Orthologous [Ortholog page] Gucy1a1 (mmu)  GUCY1A3 (gga)  GUCY1A1 (cfa)  Gucy1a1 (rno)  gucy1a1 (dre)  GUCY1A1 (mcc)  GUCY1A1 (fca) 
Subcellular
localization
wolf
cyto 6,  cyto_nucl 4,  nucl 2,  mito 1  (predict for NP_000847.2)
cyto 6,  cyto_nucl 4,  nucl 2,  mito 1  (predict for NP_001124154.1)
cyto 6,  cyto_nucl 4,  nucl 2,  mito 1  (predict for NP_001124155.1)
cyto 6,  cyto_nucl 4,  nucl 2,  mito 1  (predict for NP_001124156.1)
cyto 7,  cyto_nucl 6,  nucl 2  (predict for NP_001124157.1)
cyto 6,  cyto_nucl 4,  nucl 2,  mito 1,  pero 1,  E.R._mito 1  (predict for NP_001124159.1)
cyto 6,  cyto_nucl 4,  nucl 2,  mito 1  (predict for NP_001243378.1)
cyto 6,  cyto_nucl 4,  nucl 2,  mito 1  (predict for NP_001366595.1)
cyto 6,  cyto_nucl 4,  nucl 2,  mito 1  (predict for NP_001366596.1)
cyto 6,  cyto_nucl 4,  nucl 2,  mito 1  (predict for NP_001366597.1)
cyto 6,  cyto_nucl 4,  nucl 2,  mito 1  (predict for NP_001366598.1)
cyto 6,  cyto_nucl 4,  nucl 2,  mito 1  (predict for NP_001366599.1)
cyto 6,  cyto_nucl 4,  nucl 2,  mito 1  (predict for NP_001366600.1)
cyto 6,  cyto_nucl 4,  nucl 2,  mito 1  (predict for NP_001366601.1)
cyto 6,  cyto_nucl 4,  nucl 2,  mito 1  (predict for NP_001366602.1)
cyto 6,  cyto_nucl 4,  nucl 2,  mito 1  (predict for NP_001366603.1)
cyto 6,  cyto_nucl 4,  nucl 1,  mito 1,  pero 1,  E.R._mito 1  (predict for NP_001366604.1)
cyto 5,  cyto_nucl 3,  mito 3,  nucl 2,  mito_pero 2  (predict for NP_001366605.1)
cyto 7,  cyto_nucl 6,  nucl 2  (predict for XP_005263013.1)
cyto 7,  cyto_nucl 6,  nucl 2  (predict for XP_005263014.1)
cyto 7,  cyto_nucl 6,  nucl 2  (predict for XP_011530202.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04611 Platelet activation 4
hsa00230 Purine metabolism 3
hsa04022 cGMP-PKG signaling pathway 3
hsa04924 Renin secretion 3
hsa04270 Vascular smooth muscle contraction 3
Genes directly connected with GUCY1A1 on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
26.2 GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 [detail] 25 2983
6.4 MMRN1 multimerin 1 [detail] 0 22915
5.4 ARHGAP6 Rho GTPase activating protein 6 [detail] 0 395
4.4 SMAD1 SMAD family member 1 [detail] 0 4086
4.2 CYP7B1 cytochrome P450 family 7 subfamily B member 1 [detail] 0 9420
Coexpressed
gene list		 [Coexpressed gene list for GUCY1A1]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 2982      
Refseq ID (protein) NP_000847.2 
NP_001124154.1 
NP_001124155.1 
NP_001124156.1 
NP_001124157.1 
NP_001124159.1 
NP_001243378.1 
NP_001366595.1 
NP_001366596.1 
NP_001366597.1 
NP_001366598.1 
NP_001366599.1 
NP_001366600.1 
NP_001366601.1 
NP_001366602.1 
NP_001366603.1 
NP_001366604.1 
NP_001366605.1 
XP_005263013.1 
XP_005263014.1 
XP_011530202.1 


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