[][] hsa  MSN Gene
functional annotation
Function   moesin
GO BP
GO:0070489 [list] [network] T cell aggregation  (2 genes)  IDA  
GO:0022614 [list] [network] membrane to membrane docking  (5 genes)  IEP  
GO:0071394 [list] [network] cellular response to testosterone stimulus  (8 genes)  IDA  
GO:1902966 [list] [network] positive regulation of protein localization to early endosome  (8 genes)  IGI  
GO:2000643 [list] [network] positive regulation of early endosome to late endosome transport  (8 genes)  IGI  
GO:0071803 [list] [network] positive regulation of podosome assembly  (11 genes)  IEA  
GO:0001771 [list] [network] immunological synapse formation  (13 genes)  IDA  
GO:0045198 [list] [network] establishment of epithelial cell apical/basal polarity  (19 genes)  IMP  
GO:0072678 [list] [network] T cell migration  (29 genes)  IDA  
GO:0061028 [list] [network] establishment of endothelial barrier  (34 genes)  IGI  
GO:0042098 [list] [network] T cell proliferation  (36 genes)  IDA  
GO:0035722 [list] [network] interleukin-12-mediated signaling pathway  (47 genes)  TAS  
GO:0007159 [list] [network] leukocyte cell-cell adhesion  (54 genes)  IEP  
GO:2000401 [list] [network] regulation of lymphocyte migration  (61 genes)  IMP  
GO:0022612 [list] [network] gland morphogenesis  (99 genes)  IMP  
GO:0008360 [list] [network] regulation of cell shape  (154 genes)  IMP  
GO:1903364 [list] [network] positive regulation of cellular protein catabolic process  (156 genes)  IGI  
GO:0008361 [list] [network] regulation of cell size  (182 genes)  IMP  
GO:1902115 [list] [network] regulation of organelle assembly  (211 genes)  IGI  
GO:0050900 [list] [network] leukocyte migration  (375 genes)  IEP  
GO:0010628 [list] [network] positive regulation of gene expression  (1188 genes)  IGI  
GO:0007010 [list] [network] cytoskeleton organization  (1224 genes)  IEA  
GO CC
GO:0001931 [list] [network] uropod  (13 genes)  IEA  
GO:0031143 [list] [network] pseudopodium  (18 genes)  IDA  
GO:0031528 [list] [network] microvillus membrane  (27 genes)  IEA  
GO:0005902 [list] [network] microvillus  (91 genes)  IDA  
GO:0030175 [list] [network] filopodium  (107 genes)  IDA  
GO:0072562 [list] [network] blood microparticle  (146 genes)  HDA  
GO:0016323 [list] [network] basolateral plasma membrane  (228 genes)  IEA  
GO:0016324 [list] [network] apical plasma membrane  (364 genes)  IDA  
GO:0005925 [list] [network] focal adhesion  (421 genes)  HDA IDA  
GO:0045177 [list] [network] apical part of cell  (432 genes)  IDA  
GO:0048471 [list] [network] perinuclear region of cytoplasm  (733 genes)  IDA  
GO:0009986 [list] [network] cell surface  (898 genes)  IDA  
GO:0070062 [list] [network] extracellular exosome  (2212 genes)  HDA  
GO:0005856 [list] [network] cytoskeleton  (2326 genes)  TAS  
GO:0005615 [list] [network] extracellular space  (3622 genes)  HDA  
GO:0031982 [list] [network] vesicle  (4099 genes)  HDA  
GO:0005829 [list] [network] cytosol  (5345 genes)  TAS  
GO:0005886 [list] [network] plasma membrane  (5772 genes)  IDA  
GO:0071944 [list] [network] cell periphery  (6269 genes)  IDA  
GO:0005634 [list] [network] nucleus  (8115 genes)  HDA  
GO:0005737 [list] [network] cytoplasm  (11897 genes)  HDA  
GO MF
GO:0003725 [list] [network] double-stranded RNA binding  (79 genes)  IDA  
GO:0005200 [list] [network] structural constituent of cytoskeleton  (103 genes)  TAS  
GO:0003779 [list] [network] actin binding  (442 genes)  IEA  
GO:0050839 [list] [network] cell adhesion molecule binding  (544 genes)  IPI  
GO:0019901 [list] [network] protein kinase binding  (677 genes)  IPI  
GO:0005102 [list] [network] signaling receptor binding  (1550 genes)  IPI  
GO:0019899 [list] [network] enzyme binding  (2058 genes)  IPI  
GO:0005515 [list] [network] protein binding  (13898 genes)  IPI  
KEGG hsa04530 [list] [network] Tight junction (169 genes)
hsa04670 [list] [network] Leukocyte transendothelial migration (114 genes)
hsa04810 [list] [network] Regulation of actin cytoskeleton (218 genes)
hsa05162 [list] [network] Measles (139 genes)
hsa05205 [list] [network] Proteoglycans in cancer (205 genes)
Protein NP_002435.1  XP_005262326.1  XP_011529261.1  XP_016885034.1  XP_016885035.1 
BLAST NP_002435.1  XP_005262326.1  XP_011529261.1  XP_016885034.1  XP_016885035.1 
Orthologous [Ortholog page] NF2 (hsa)RDX (hsa)EZR (hsa)Msn (mmu)Nf2 (mmu)Rdx (mmu)Ezr (mmu)Nf2 (rno)Moe (dme)Mer (dme)Ezr (rno)Msn (rno)erm-1 (cel)msna (dre)Rdx (rno)NF2 (gga)RDX (gga)EZR (gga)ezra (dre)nf2b (dre)NF2L (gga)MSN (gga)NF2 (cfa)RDX (cfa)EZR (cfa)MSN (cfa)msnb (dre)nf2a (dre)ezrb (dre)EZR (mcc)RDX (mcc)MSN (mcc)NF2 (mcc)MSN (fca)NF2 (fca)RDX (fca)EZR (fca)
Subcellular
localization
wolf
cyto 6,  nucl 3,  cyto_mito 3,  cyto_plas 3,  cyto_golg 3  (predict for NP_002435.1)
cyto_nucl 4,  nucl 4,  cyto 4,  cysk 1  (predict for XP_005262326.1)
cyto 7,  cyto_nucl 4,  nucl 1,  cysk 1  (predict for XP_011529261.1)
nucl 5,  cyto_nucl 4,  cyto 3,  cysk 1  (predict for XP_016885034.1)
nucl 5,  cyto_nucl 4,  cyto 3,  cysk 1  (predict for XP_016885035.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04810 Regulation of actin cytoskeleton 11
hsa05131 Shigellosis 9
hsa04530 Tight junction 8
hsa04144 Endocytosis 7
hsa04510 Focal adhesion 7
Genes directly connected with MSN on the network
coex z* Locus Function* Coexpression
detail
CoexPub Entrez Gene ID*
8.1 FLNA filamin A [detail] 18 2316
7.5 CAP1 cyclase associated actin cytoskeleton regulatory protein 1 [detail] 5 10487
7.3 MYH9 myosin heavy chain 9 [detail] 8 4627
6.8 GNAI2 G protein subunit alpha i2 [detail] 0 2771
5.7 ITGA5 integrin subunit alpha 5 [detail] 0 3678
5.2 ETS1 ETS proto-oncogene 1, transcription factor [detail] 0 2113
4.6 SH3KBP1 SH3 domain containing kinase binding protein 1 [detail] 0 30011
Coexpressed
gene list
[Coexpressed gene list for MSN]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 4478    
Refseq ID (protein) NP_002435.1 
XP_005262326.1 
XP_011529261.1 
XP_016885034.1 
XP_016885035.1 


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