| functional annotation |
| Function |
moesin |
|
| GO BP |
|
GO:0070489 [list] [network] T cell aggregation
|
(2 genes)
|
IDA
|
 |
|
GO:0022614 [list] [network] membrane to membrane docking
|
(5 genes)
|
IEP
|
 |
|
GO:0071394 [list] [network] cellular response to testosterone stimulus
|
(8 genes)
|
IDA
|
 |
|
GO:1902966 [list] [network] positive regulation of protein localization to early endosome
|
(8 genes)
|
IGI
|
 |
|
GO:2000643 [list] [network] positive regulation of early endosome to late endosome transport
|
(8 genes)
|
IGI
|
 |
|
GO:0071803 [list] [network] positive regulation of podosome assembly
|
(11 genes)
|
IEA
|
 |
|
GO:0001771 [list] [network] immunological synapse formation
|
(13 genes)
|
IDA
|
 |
|
GO:0045198 [list] [network] establishment of epithelial cell apical/basal polarity
|
(19 genes)
|
IMP
|
 |
|
GO:0072678 [list] [network] T cell migration
|
(29 genes)
|
IDA
|
 |
|
GO:0061028 [list] [network] establishment of endothelial barrier
|
(34 genes)
|
IGI
|
 |
|
GO:0042098 [list] [network] T cell proliferation
|
(36 genes)
|
IDA
|
 |
|
GO:0035722 [list] [network] interleukin-12-mediated signaling pathway
|
(47 genes)
|
TAS
|
 |
|
GO:0007159 [list] [network] leukocyte cell-cell adhesion
|
(54 genes)
|
IEP
|
 |
|
GO:2000401 [list] [network] regulation of lymphocyte migration
|
(61 genes)
|
IMP
|
 |
|
GO:0022612 [list] [network] gland morphogenesis
|
(99 genes)
|
IMP
|
 |
|
GO:0008360 [list] [network] regulation of cell shape
|
(154 genes)
|
IMP
|
 |
|
GO:1903364 [list] [network] positive regulation of cellular protein catabolic process
|
(156 genes)
|
IGI
|
 |
|
GO:0008361 [list] [network] regulation of cell size
|
(182 genes)
|
IMP
|
 |
|
GO:1902115 [list] [network] regulation of organelle assembly
|
(211 genes)
|
IGI
|
 |
|
GO:0050900 [list] [network] leukocyte migration
|
(375 genes)
|
IEP
|
 |
|
GO:0010628 [list] [network] positive regulation of gene expression
|
(1188 genes)
|
IGI
|
 |
|
GO:0007010 [list] [network] cytoskeleton organization
|
(1224 genes)
|
IEA
|
 |
|
| GO CC |
|
| GO MF |
|
GO:0003725 [list] [network] double-stranded RNA binding
|
(79 genes)
|
IDA
|
 |
|
GO:0005200 [list] [network] structural constituent of cytoskeleton
|
(103 genes)
|
TAS
|
 |
|
GO:0003779 [list] [network] actin binding
|
(442 genes)
|
IEA
|
 |
|
GO:0050839 [list] [network] cell adhesion molecule binding
|
(544 genes)
|
IPI
|
 |
|
GO:0019901 [list] [network] protein kinase binding
|
(677 genes)
|
IPI
|
 |
|
GO:0005102 [list] [network] signaling receptor binding
|
(1550 genes)
|
IPI
|
 |
|
GO:0019899 [list] [network] enzyme binding
|
(2058 genes)
|
IPI
|
 |
|
GO:0005515 [list] [network] protein binding
|
(13898 genes)
|
IPI
|
 |
|
| KEGG |
hsa04530 [list] [network] Tight junction (169 genes) |
 |
| hsa04670 [list] [network] Leukocyte transendothelial migration (114 genes) |
 |
| hsa04810 [list] [network] Regulation of actin cytoskeleton (218 genes) |
 |
| hsa05162 [list] [network] Measles (139 genes) |
 |
| hsa05205 [list] [network] Proteoglycans in cancer (205 genes) |
 |
| Protein |
NP_002435.1
XP_005262326.1
XP_011529261.1
XP_016885034.1
XP_016885035.1
|
| BLAST |
NP_002435.1
XP_005262326.1
XP_011529261.1
XP_016885034.1
XP_016885035.1
|
| Orthologous |
[Ortholog page]
NF2 (hsa)
RDX (hsa)
EZR (hsa)
Msn (mmu)
Nf2 (mmu)
Rdx (mmu)
Ezr (mmu)
Nf2 (rno)
Moe (dme)
Mer (dme)
Ezr (rno)
Msn (rno)
erm-1 (cel)
msna (dre)
Rdx (rno)
NF2 (gga)
RDX (gga)
EZR (gga)
ezra (dre)
nf2b (dre)
NF2L (gga)
MSN (gga)
NF2 (cfa)
RDX (cfa)
EZR (cfa)
MSN (cfa)
msnb (dre)
nf2a (dre)
ezrb (dre)
EZR (mcc)
RDX (mcc)
MSN (mcc)
NF2 (mcc)
MSN (fca)
NF2 (fca)
RDX (fca)
EZR (fca)
|
Subcellular localization wolf |
|
cyto 6,
nucl 3,
cyto_mito 3,
cyto_plas 3,
cyto_golg 3
|
(predict for NP_002435.1)
|
|
cyto_nucl 4,
nucl 4,
cyto 4,
cysk 1
|
(predict for XP_005262326.1)
|
|
cyto 7,
cyto_nucl 4,
nucl 1,
cysk 1
|
(predict for XP_011529261.1)
|
|
nucl 5,
cyto_nucl 4,
cyto 3,
cysk 1
|
(predict for XP_016885034.1)
|
|
nucl 5,
cyto_nucl 4,
cyto 3,
cysk 1
|
(predict for XP_016885035.1)
|
|
| Gene coexpression |
Network*for coexpressed genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| hsa04810 |
Regulation of actin cytoskeleton |
11 |
|
| hsa05131 |
Shigellosis |
9 |
|
| hsa04530 |
Tight junction |
8 |
|
| hsa04144 |
Endocytosis |
7 |
|
| hsa04510 |
Focal adhesion |
7 |
|
Genes directly connected with MSN on the network
| coex z* |
Locus |
Function* |
Coexpression detail |
CoexPub |
Entrez Gene ID* |
| 8.1 |
FLNA |
filamin A |
[detail] |
18 |
2316 |
| 7.5 |
CAP1 |
cyclase associated actin cytoskeleton regulatory protein 1 |
[detail] |
5 |
10487 |
| 7.3 |
MYH9 |
myosin heavy chain 9 |
[detail] |
8 |
4627 |
| 6.8 |
GNAI2 |
G protein subunit alpha i2 |
[detail] |
0 |
2771 |
| 5.7 |
ITGA5 |
integrin subunit alpha 5 |
[detail] |
0 |
3678 |
| 5.2 |
ETS1 |
ETS proto-oncogene 1, transcription factor |
[detail] |
0 |
2113 |
| 4.6 |
SH3KBP1 |
SH3 domain containing kinase binding protein 1 |
[detail] |
0 |
30011 |
|
Coexpressed gene list |
[Coexpressed gene list for MSN]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|