| functional annotation |
| Function |
folate receptor alpha |
|
| GO BP |
|
GO:0003147 [list] [network] neural crest cell migration involved in heart formation
|
(1 genes)
|
ISO
|
 |
|
GO:0071231 [list] [network] cellular response to folic acid
|
(2 genes)
|
ISO
|
|
|
GO:0061713 [list] [network] anterior neural tube closure
|
(4 genes)
|
ISO
|
|
|
GO:0003253 [list] [network] cardiac neural crest cell migration involved in outflow tract morphogenesis
|
(5 genes)
|
ISO
|
|
|
GO:1904447 [list] [network] folate import across plasma membrane
|
(5 genes)
|
IEA
|
|
|
GO:0015884 [list] [network] folic acid transport
|
(8 genes)
|
ISO
|
|
|
GO:0046655 [list] [network] folic acid metabolic process
|
(8 genes)
|
ISO
|
|
|
GO:0061626 [list] [network] pharyngeal arch artery morphogenesis
|
(10 genes)
|
ISO
|
|
|
GO:0007342 [list] [network] fusion of sperm to egg plasma membrane involved in single fertilization
|
(20 genes)
|
IBA
|
|
|
GO:0031103 [list] [network] axon regeneration
|
(34 genes)
|
ISO
|
|
|
GO:0035036 [list] [network] sperm-egg recognition
|
(51 genes)
|
IBA
|
|
|
GO:0001947 [list] [network] heart looping
|
(61 genes)
|
ISO
|
|
|
GO:0048678 [list] [network] response to axon injury
|
(86 genes)
|
ISO
|
|
|
GO:0017015 [list] [network] regulation of transforming growth factor beta receptor signaling pathway
|
(123 genes)
|
ISO
|
|
|
GO:0060828 [list] [network] regulation of canonical Wnt signaling pathway
|
(242 genes)
|
ISO
|
|
|
GO:0007155 [list] [network] cell adhesion
|
(785 genes)
|
IBA
|
|
|
| GO CC |
|
GO:0031362 [list] [network] anchored component of external side of plasma membrane
|
(20 genes)
|
IBA
ISO
|
|
|
GO:0046658 [list] [network] anchored component of plasma membrane
|
(73 genes)
|
IDA
|
|
|
GO:0031526 [list] [network] brush border membrane
|
(76 genes)
|
IDA
|
|
|
GO:0005903 [list] [network] brush border
|
(138 genes)
|
IDA
|
|
|
GO:0016323 [list] [network] basolateral plasma membrane
|
(260 genes)
|
ISO
|
|
|
GO:0016324 [list] [network] apical plasma membrane
|
(397 genes)
|
ISO
|
|
|
GO:0005634 [list] [network] nucleus
|
(6599 genes)
|
ISO
|
|
|
| GO MF |
|
GO:0061714 [list] [network] folic acid receptor activity
|
(2 genes)
|
ISO
|
|
|
GO:0051870 [list] [network] methotrexate binding
|
(3 genes)
|
ISO
|
|
|
GO:0005542 [list] [network] folic acid binding
|
(14 genes)
|
IDA
ISO
|
|
|
GO:0038023 [list] [network] signaling receptor activity
|
(2470 genes)
|
IBA
|
|
|
| KEGG |
rno01523 [list] [network] Antifolate resistance (29 genes) |
 |
| rno04144 [list] [network] Endocytosis (274 genes) |
|
| Protein |
NP_598211.2
XP_006229904.1
XP_017444199.1
XP_017444200.1
XP_038941593.1
XP_038941635.1
XP_038941685.1
|
| BLAST |
NP_598211.2
XP_006229904.1
XP_017444199.1
XP_017444200.1
XP_038941593.1
XP_038941635.1
XP_038941685.1
|
| Orthologous |
[Ortholog page]
FOLR1 (hsa)
FOLR2 (hsa)
FOLR3 (hsa)
Folr1 (mmu)
Folr2 (mmu)
Izumo1r (mmu)
Folr2 (rno)
IZUMO1R (hsa)
FOLR1 (gga)
LOC476816 (cfa)
IZUMO1R (cfa)
LOC609612 (cfa)
Izumo1r (rno)
IZUMO1R (mcc)
LOC718347 (mcc)
LOC718378 (mcc)
FOLR1 (mcc)
FOLR2 (mcc)
folr (dre)
LOC100684665 (cfa)
FOLR1 (fca)
LOC101084733 (fca)
IZUMO1R (fca)
LOC101095853 (fca)
FOLR3 (gga)
|
Subcellular
localization
wolf |
|
extr 9,
lyso 1
|
(predict for NP_598211.2)
|
|
extr 9,
lyso 1
|
(predict for XP_006229904.1)
|
|
extr 9,
lyso 1
|
(predict for XP_017444199.1)
|
|
extr 9,
lyso 1
|
(predict for XP_017444200.1)
|
|
extr 9,
lyso 1
|
(predict for XP_038941593.1)
|
|
extr 9,
lyso 1
|
(predict for XP_038941635.1)
|
|
extr 9,
lyso 1
|
(predict for XP_038941685.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| rno04976 |
Bile secretion |
2 |
 |
| rno04978 |
Mineral absorption |
2 |
 |
| rno04514 |
Cell adhesion molecules |
2 |
 |
Genes directly connected with Folr1 on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
Entrez Gene ID* |
| 7.1 |
Mfrp |
membrane frizzled-related protein |
[detail] |
315597 |
| 6.5 |
Cltrn |
collectrin, amino acid transport regulator |
[detail] |
57395 |
| 6.2 |
Cldn2 |
claudin 2 |
[detail] |
300920 |
| 5.5 |
Steap1 |
STEAP family member 1 |
[detail] |
297738 |
| 5.4 |
Mdk |
midkine |
[detail] |
81517 |
| 4.1 |
Ca12 |
carbonic anhydrase 12 |
[detail] |
363085 |
| 3.8 |
Trpv4 |
transient receptor potential cation channel, subfamily V, member 4 |
[detail] |
66026 |
|
Coexpressed
gene list |
[Coexpressed gene list for Folr1]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
Folr1 Gene
