KEGG 01523 Antifolate resistance

30  hsa genes in this database.
29  mmu genes in this database.
29  rno genes in this database.
32  mcc genes in this database.
28  cfa genes in this database.
29  fca genes in this database.

List of genes in hsa


Shaded genes do not have coexpression data.
For search Locus* Target* Alias Function*
239 , M ALOX12 arachidonate 12-lipoxygenase, 12S type
471 , Y ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
1147 , Y CHUK component of inhibitor of nuclear factor kappa B kinase complex
1244 , P ABCC2 ATP binding cassette subfamily C member 2
1719 , Y DHFR dihydrofolate reductase
2348 , S FOLR1 folate receptor alpha
2350 , S FOLR2 folate receptor beta
2352 , S FOLR3 folate receptor gamma
2356 , Y FPGS folylpolyglutamate synthase
2618 , Y GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
3551 , Y_N IKBKB inhibitor of nuclear factor kappa B kinase subunit beta
3553 , N IL1B interleukin 1 beta
3569 , S IL6 interleukin 6
4363 , P ABCC1 ATP binding cassette subfamily C member 1
4524 , M MTHFR methylenetetrahydrofolate reductase
4790 , Y NFKB1 nuclear factor kappa B subunit 1
5970 , N RELA RELA proto-oncogene, NF-kB subunit
6470 , Y SHMT1 serine hydroxymethyltransferase 1
6472 , M SHMT2 serine hydroxymethyltransferase 2
6573 , P SLC19A1 solute carrier family 19 member 1
7124 , P TNF tumor necrosis factor
7298 , Y TYMS thymidylate synthetase
8517 , Y IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
8714 , P ABCC3 ATP binding cassette subfamily C member 3
8836 , S GGH gamma-glutamyl hydrolase
9429 , P ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group)
10057 , P ABCC5 ATP binding cassette subfamily C member 5
10257 , P ABCC4 ATP binding cassette subfamily C member 4
113235 , P SLC46A1 solute carrier family 46 member 1
200895 , M DHFR2 dihydrofolate reductase 2


List of genes in mmu


Shaded genes do not have coexpression data.
For search Locus* Target* Alias Function*
11684 , Y Alox12 arachidonate 12-lipoxygenase
11685 , Y Alox12e arachidonate lipoxygenase, epidermal
12675 , Y Chuk conserved helix-loop-helix ubiquitous kinase
12780 , P Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
13361 , Y Dhfr dihydrofolate reductase
14275 , S Folr1 folate receptor 1 (adult)
14276 , S Folr2 folate receptor 2 (fetal)
14287 , M Fpgs folylpolyglutamyl synthetase
14450 , Y Gart phosphoribosylglycinamide formyltransferase
14590 , S Ggh gamma-glutamyl hydrolase
16150 , Y Ikbkb inhibitor of kappaB kinase beta
16151 , Y Ikbkg inhibitor of kappaB kinase gamma
16176 , N Il1b interleukin 1 beta
16193 , S Il6 interleukin 6
17250 , P Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
17769 , N Mthfr methylenetetrahydrofolate reductase
18033 , Y Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
19697 , M Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian)
20425 , Y Shmt1 serine hydroxymethyltransferase 1 (soluble)
20509 , P Slc19a1 solute carrier family 19 (folate transporter), member 1
21926 , P Tnf tumor necrosis factor
22171 , Y Tyms thymidylate synthase
26357 , P Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group)
27416 , P Abcc5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
52466 , P Slc46a1 solute carrier family 46, member 1
76408 , P Abcc3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
108037 , M Shmt2 serine hydroxymethyltransferase 2 (mitochondrial)
108147 , Y Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
239273 , P Abcc4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4


List of genes in rno


Shaded genes do not have coexpression data.
For search Locus* Target* Alias Function*
24312 , Y Dhfr dihydrofolate reductase
24494 , N Il1b interleukin 1 beta
24498 , S Il6 interleukin 6
24565 , P Abcc1 ATP binding cassette subfamily C member 1
24835 , P Tnf tumor necrosis factor
25303 , P Abcc2 ATP binding cassette subfamily C member 2
25455 , S Ggh gamma-glutamyl hydrolase
29261 , Y Tyms thymidylate synthetase
29723 , P Slc19a1 solute carrier family 19 member 1
81643 , Y Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
81736 , Y Nfkb1 nuclear factor kappa B subunit 1
84351 , Y Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta
116721 , P Abcc5 ATP binding cassette subfamily C member 5
140668 , P Abcc3 ATP binding cassette subfamily C member 3
170924 , P Abcc4 ATP binding cassette subfamily C member 4
171049 , S Folr1 folate receptor alpha
287379 , K Shmt1 serine hydroxymethyltransferase 1
287454 , M Alox12 arachidonate 12-lipoxygenase, 12S type
288259 , Y Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
293154 , S Folr2 folate receptor beta
299857 , M Shmt2 serine hydroxymethyltransferase 2
303252 , Y Alox12e arachidonate 12-lipoxygenase, epidermal
303333 , P Slc46a1 solute carrier family 46 member 1
309165 , N Rela RELA proto-oncogene, NF-kB subunit
309295 , Y Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
309361 , Y Chuk component of inhibitor of nuclear factor kappa B kinase complex
312382 , P Abcg2 ATP binding cassette subfamily G member 2
362657 , N Mthfr methylenetetrahydrofolate reductase
687266 , M Fpgs folylpolyglutamate synthase


List of genes in mcc


Shaded genes do not have coexpression data.
For search Locus* Target* Alias Function*
574169 , P ABCC2 ATP binding cassette subfamily C member 2
574307 , P ABCG2 ATP binding cassette subfamily G member 2
694819 , Y ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
695407 , P ABCC4 ATP binding cassette subfamily C member 4
697580 , Y TYMS thymidylate synthetase
699587 , M FPGS folylpolyglutamate synthase
700747 , S GGH gamma-glutamyl hydrolase
701186 , Y SHMT1 serine hydroxymethyltransferase 1
701237 , Y IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
704326 , P ABCC5 ATP binding cassette subfamily C member 5
704683 , Y IKBKB inhibitor of nuclear factor kappa B kinase subunit beta
704701 , N IL1B interleukin 1 beta
704926 , Y GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
705819 , S IL6 interleukin 6
706339 , P ABCC3 ATP binding cassette subfamily C member 3
707382 , S LOC707382 dihydrofolate reductase
708727 , P SLC46A1 solute carrier family 46 member 1
709511 , Y CHUK component of inhibitor of nuclear factor kappa B kinase complex
710324 , Y NFKB1 nuclear factor kappa B subunit 1
711268 , Y DHFR dihydrofolate reductase
713748 , M ALOX12 arachidonate 12-lipoxygenase, 12S type
714433 , Y SHMT2 serine hydroxymethyltransferase 2
714840 , N MTHFR methylenetetrahydrofolate reductase
715467 , P TNF tumor necrosis factor
715919 , N RELA RELA proto-oncogene, NF-kB subunit
717857 , P ABCC1 ATP binding cassette subfamily C member 1
718347 , S LOC718347 folate receptor gamma-like
718378 , S LOC718378 folate receptor gamma-like
718388 , S FOLR1 folate receptor alpha
718405 , S FOLR2 folate receptor beta
721917 , P SLC19A1 solute carrier family 19 member 1
106996159 , Y DHFR2 dihydrofolate reductase 2


List of genes in cfa


Shaded genes do not have coexpression data.
For search Locus* Target* Alias Function*
403453 , P ABCC1 ATP binding cassette subfamily C member 1
403632 , P ABCC2 ATP binding cassette subfamily C member 2
403922 , P TNF tumor necrosis factor
403974 , N IL1B interleukin 1 beta
403985 , S IL6 interleukin 6
442859 , Y NFKB1 nuclear factor kappa B subunit 1
476816 , S LOC476816 folate receptor beta
477796 , Y CHUK component of inhibitor of nuclear factor kappa B kinase complex
478230 , N MTHFR methylenetetrahydrofolate reductase
478472 , P ABCG2 ATP binding cassette subfamily G member 2
478648 , P ABCC5 ATP binding cassette subfamily C member 5
479165 , Y DHFR dihydrofolate reductase
479476 , M ALOX12 arachidonate 12-lipoxygenase, 12S type
482839 , Y IKBKB inhibitor of nuclear factor kappa B kinase subunit beta
483729 , M RELA RELA proto-oncogene, NF-kB subunit
485523 , P ABCC4 ATP binding cassette subfamily C member 4
488513 , Y ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
489536 , Y SHMT1 serine hydroxymethyltransferase 1
491084 , P ABCC3 ATP binding cassette subfamily C member 3
491166 , P SLC46A1 solute carrier family 46 member 1
491606 , P SLC19A1 solute carrier family 19 member 1
607417 , Y TYMS thymidylate synthetase
607458 , Y SHMT2 serine hydroxymethyltransferase 2
609048 , Y LOC609048 dihydrofolate reductase
609612 , S LOC609612 folate receptor alpha
100855785 , M FPGS folylpolyglutamate synthase
100856436 , S GGH gamma-glutamyl hydrolase
100856570 , Y LOC100856570 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase


List of genes in fca


Shaded genes do not have coexpression data.
For search Locus* Target* Alias Function*
493687 , S IL6 interleukin 6
493755 , P TNF tumor necrosis factor
768274 , Y_N IL1B interleukin 1 beta
100142682 , Y IKBKB inhibitor of nuclear factor kappa B kinase subunit beta
100142683 , Y NFKB1 nuclear factor kappa B subunit 1
101081485 , Y ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
101084221 , S FOLR1 folate receptor alpha
101084733 , S LOC101084733 folate receptor gamma-like
101085924 , P ABCC2 ATP binding cassette subfamily C member 2
101086247 , P SLC19A1 solute carrier family 19 member 1
101086266 , Y_N SHMT1 serine hydroxymethyltransferase 1
101086544 , N IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
101087772 , Y GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
101087964 , Y DHFR dihydrofolate reductase
101090542 , P ABCC5 ATP binding cassette subfamily C member 5
101091231 , Y TYMS thymidylate synthetase
101091290 , M SHMT2 serine hydroxymethyltransferase 2
101092966 , M FPGS folylpolyglutamate synthase
101094017 , P ABCG2 ATP binding cassette subfamily G member 2
101094304 , M LOC101094304 arachidonate 12-lipoxygenase, 12S-type
101095617 , Y CHUK component of inhibitor of nuclear factor kappa B kinase complex
101095853 , S LOC101095853 folate receptor beta
101096129 , P ABCC4 ATP binding cassette subfamily C member 4
101096604 , N RELA RELA proto-oncogene, NF-kB subunit
101098502 , P ABCC3 ATP binding cassette subfamily C member 3
101100096 , P SLC46A1 solute carrier family 46 member 1
101100576 , N MTHFR methylenetetrahydrofolate reductase
101100943 , S GGH gamma-glutamyl hydrolase
101101279 , P ABCC1 ATP binding cassette subfamily C member 1


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