KEGG 01523 Antifolate resistance
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa00230 Purine metabolism 2
hsa00670 One carbon pool by folate 2
hsa01523 Antifolate resistance 2
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu01523 Antifolate resistance 12
mmu00670 One carbon pool by folate 6
mmu04064 NF-kappa B signaling pathway 6
mmu05134 Legionellosis 6
mmu01240 Biosynthesis of cofactors 5
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno04010 MAPK signaling pathway 9
rno01523 Antifolate resistance 9
rno04064 NF-kappa B signaling pathway 9
rno04625 C-type lectin receptor signaling pathway 9
rno04380 Osteoclast differentiation 8
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc01523 Antifolate resistance 8
mcc00670 One carbon pool by folate 4
mcc00230 Purine metabolism 2
mcc04060 Cytokine-cytokine receptor interaction 2
mcc04620 Toll-like receptor signaling pathway 2
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa01523 Antifolate resistance 4
cfa04060 Cytokine-cytokine receptor interaction 3
cfa04620 Toll-like receptor signaling pathway 3
cfa04621 NOD-like receptor signaling pathway 3
cfa04657 IL-17 signaling pathway 3
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca01523 Antifolate resistance 3
fca04144 Endocytosis 3
Gene list in the network
Symbol Function*
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
RUVBL1 RuvB like AAA ATPase 1
Symbol Function*
Dhfr dihydrofolate reductase
Fpgs folylpolyglutamyl synthetase
Gart phosphoribosylglycinamide formyltransferase
Il1b interleukin 1 beta
Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
Mybbp1a MYB binding protein (P160) 1a
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian)
Cxcl2 chemokine (C-X-C motif) ligand 2
Shmt1 serine hydroxymethyltransferase 1 (soluble)
Tnf tumor necrosis factor
Tyms thymidylate synthase
Umps uridine monophosphate synthetase
Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Mthfd1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
Pecr peroxisomal trans-2-enoyl-CoA reductase
Abcc4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
Symbol Function*
Il1a interleukin 1 alpha
Il1b interleukin 1 beta
Il6 interleukin 6
Tnf tumor necrosis factor
Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
Nfkb1 nuclear factor kappa B subunit 1
Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta
Cxcl2 C-X-C motif chemokine ligand 2
Ccl4 C-C motif chemokine ligand 4
Shmt1 serine hydroxymethyltransferase 1
Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
Mapkapk2 MAPK activated protein kinase 2
Rela RELA proto-oncogene, NF-kB subunit
Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
Nfkb2 nuclear factor kappa B subunit 2
Symbol Function*
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
ACOD1 aconitate decarboxylase 1
TYMS thymidylate synthetase
IL1B interleukin 1 beta
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
IL6 interleukin 6
DHFR dihydrofolate reductase
NOLC1 nucleolar and coiled-body phosphoprotein 1
LOC718347 folate receptor gamma-like
FOLR1 folate receptor alpha
Symbol Function*
CXCL8 C-X-C motif chemokine ligand 8
IL1B interleukin 1 beta
IL6 interleukin 6
DHFR dihydrofolate reductase
LOC609048 dihydrofolate reductase
Symbol Function*
FOLR1 folate receptor alpha
LOC101084733 folate receptor gamma-like
AIF1 allograft inflammatory factor 1
LOC101095853 folate receptor beta
PILRA paired immunoglobin like type 2 receptor alpha


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