[←][→] hsa  CCN4 Gene
functional annotation
Function   cellular communication network factor 4  
GO BP
GO:0032331 [list] [network] negative regulation of chondrocyte differentiation  (24 genes)  IEA  
GO:0030316 [list] [network] osteoclast differentiation  (39 genes)  IEA  
GO:0014911 [list] [network] positive regulation of smooth muscle cell migration  (46 genes)  ISS  
GO:0045599 [list] [network] negative regulation of fat cell differentiation  (55 genes)  IEA  
GO:0090303 [list] [network] positive regulation of wound healing  (59 genes)  IEA  
GO:0045669 [list] [network] positive regulation of osteoblast differentiation  (69 genes)  IMP  
GO:0048661 [list] [network] positive regulation of smooth muscle cell proliferation  (102 genes)  ISS  
GO:0001649 [list] [network] osteoblast differentiation  (126 genes)  IEA  
GO:0050729 [list] [network] positive regulation of inflammatory response  (141 genes)  IDA  
GO:0060348 [list] [network] bone development  (184 genes)  IEA  
GO:0030177 [list] [network] positive regulation of Wnt signaling pathway  (185 genes)  IEA  
GO:0042593 [list] [network] glucose homeostasis  (202 genes)  IEA  
GO:0016055 [list] [network] Wnt signaling pathway  (344 genes)  IEA  
GO:0001817 [list] [network] regulation of cytokine production  (831 genes)  IDA  
GO:0007155 [list] [network] cell adhesion  (942 genes)  IBA  
GO:0060548 [list] [network] negative regulation of cell death  (1024 genes)  IBA  
GO:0007267 [list] [network] cell-cell signaling  (1120 genes)  TAS  
GO:0007165 [list] [network] signal transduction  (5169 genes)  IBA  
GO CC
GO:0031012 [list] [network] extracellular matrix  (570 genes)  IBA  
GO:0005615 [list] [network] extracellular space  (3622 genes)  IDA NAS  
GO:0005829 [list] [network] cytosol  (5345 genes)  IDA  
GO MF
GO:0005520 [list] [network] insulin-like growth factor binding  (29 genes)  IEA  
GO:0005178 [list] [network] integrin binding  (144 genes)  IBA  
GO:0008201 [list] [network] heparin binding  (166 genes)  IBA  
GO:0005515 [list] [network] protein binding  (13898 genes)  IPI  
KEGG hsa04310 [list] [network] Wnt signaling pathway (167 genes)
Protein NP_001191798.1  NP_001191799.1  NP_003873.1  NP_543028.1  XP_024303087.1  XP_024303088.1  XP_024303089.1 
BLAST NP_001191798.1  NP_001191799.1  NP_003873.1  NP_543028.1  XP_024303087.1  XP_024303088.1  XP_024303089.1 
Orthologous [Ortholog page] CCN2 (hsa)  CCN1 (hsa)  CCN3 (hsa)  CCN6 (hsa)  CCN5 (hsa)  Ccn2 (mmu)  Ccn1 (mmu)  Ccn3 (mmu)  Ccn4 (mmu)  Ccn5 (mmu)  Ccn5 (rno)  Ccn (dme)  Ccn2 (rno)  Ccn4 (rno)  Ccn3 (rno)  Ccn1 (rno)  ccn2a (dre)  Ccn6 (mmu)  NOV (gga)  CCN3 (gga)  ccn1 (dre)  WISP2 (gga)  WISP1 (gga)  CYR61 (gga)  CCN3 (cfa)  CCN2 (cfa)  CCN1 (cfa)  CCN4 (cfa)  si:ch211-106h11.3 (dre)  Ccn6 (rno)  ccn1l1 (dre)  ccn1l2 (dre)  ccn4a (dre)  CCN5 (cfa)  CCN6 (mcc)  CCN4 (mcc)  CCN3 (mcc)  CCN2 (mcc)  CCN1 (mcc)  CCN5 (mcc)  CTGFL (gga)  ccn4b (dre)  ccn6 (dre)  ccn5 (dre)  ccn2b (dre)  CCN6 (cfa)  CCN6 (fca)  CCN5 (fca)  CCN4 (fca)  CCN2 (fca)  CCN3 (fca)  CCN1 (fca)  WISP3 (gga) 
Subcellular
localization
wolf
extr 10  (predict for NP_001191798.1)
extr 7,  mito 2,  nucl 0,  cyto 0,  cyto_nucl 0,  lyso 0,  golg 0,  cyto_golg 0  (predict for NP_001191799.1)
plas 7,  E.R. 1,  extr 1  (predict for NP_003873.1)
extr 9  (predict for NP_543028.1)
mito 5,  extr 2,  cyto_nucl 1,  nucl 1,  cyto 1  (predict for XP_024303087.1)
extr 5,  mito 3,  lyso 1,  nucl 0,  cyto_nucl 0  (predict for XP_024303088.1)
extr 7,  cyto 2,  cyto_nucl 1,  cyto_pero 1  (predict for XP_024303089.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04974 Protein digestion and absorption 6
hsa04151 PI3K-Akt signaling pathway 4
hsa04510 Focal adhesion 4
hsa04512 ECM-receptor interaction 4
hsa05165 Human papillomavirus infection 4
Genes directly connected with CCN4 on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
6.8 COL3A1 collagen type III alpha 1 chain [detail] 1 1281
6.7 ITGA11 integrin subunit alpha 11 [detail] 1 22801
6.6 FIBIN fin bud initiation factor homolog [detail] 1 387758
5.7 CTHRC1 collagen triple helix repeat containing 1 [detail] 0 115908
5.2 KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 [detail] 0 23704
5.2 TG thyroglobulin [detail] 0 7038
4.4 GREM1 gremlin 1, DAN family BMP antagonist [detail] 0 26585
Coexpressed
gene list		 [Coexpressed gene list for CCN4]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 8840      
Refseq ID (protein) NP_001191798.1 
NP_001191799.1 
NP_003873.1 
NP_543028.1 
XP_024303087.1 
XP_024303088.1 
XP_024303089.1 


The preparation time of this page was 0.2 [sec].