| functional annotation |
| Function |
glutamate--cysteine ligase |
|
| GO BP |
|
| GO CC |
|
| GO MF |
|
GO:0004357 [list] [network] glutamate-cysteine ligase activity
|
(1 genes)
|
IBA
IDA
IEA
IMP
|
 |
|
GO:0016874 [list] [network] ligase activity
|
(123 genes)
|
IEA
|
|
|
GO:0005524 [list] [network] ATP binding
|
(672 genes)
|
IEA
|
|
|
GO:0000166 [list] [network] nucleotide binding
|
(894 genes)
|
IEA
|
|
|
GO:0003824 [list] [network] catalytic activity
|
(2321 genes)
|
IEA
|
|
|
| KEGG |
sce00270 [list] [network] Cysteine and methionine metabolism (43 genes) |
 |
| sce00480 [list] [network] Glutathione metabolism (23 genes) |
|
| sce01240 [list] [network] Biosynthesis of cofactors (131 genes) |
|
| Protein |
NP_012434.1
|
| BLAST |
NP_012434.1
|
| Orthologous |
[Ortholog page]
GCLC (hsa)
Gclc (mmu)
Gclc (rno)
Gclc (dme)
gcs-1 (cel)
gclc (dre)
GCLC (gga)
GCLC (cfa)
GCLC (mcc)
cut4 (spo)
GCLC (fca)
|
Subcellular
localization
wolf |
|
cyto_nucl 2,
nucl 2,
cyto 2,
E.R. 2,
mito 1,
extr 1,
pero 1,
golg 1
|
(predict for NP_012434.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| sce00270 |
Cysteine and methionine metabolism |
6 |
 |
| sce00920 |
Sulfur metabolism |
5 |
 |
| sce01230 |
Biosynthesis of amino acids |
5 |
 |
| sce01240 |
Biosynthesis of cofactors |
3 |
 |
| sce00450 |
Selenocompound metabolism |
3 |
 |
Genes directly connected with GSH1 on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
Entrez Gene ID* |
| 6.0 |
MET2 |
homoserine O-acetyltransferase |
[detail] |
855444 |
| 6.0 |
MUP3 |
Mup3p |
[detail] |
856349 |
| 5.8 |
CYS4 |
cystathionine beta-synthase CYS4 |
[detail] |
853059 |
|
Coexpressed
gene list |
[Coexpressed gene list for GSH1]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
GSH1 Gene
