KEGG 00270 Cysteine and methionine metabolism
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) gga(Chicken) dre(Zebrafish) dme(Fly) cel(Nematoda) mcc(Monkey) cfa(Dog) sce(Budding yeast) spo(Fission yeast) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa00270 Cysteine and methionine metabolism 20
hsa01230 Biosynthesis of amino acids 11
hsa01200 Carbon metabolism 10
hsa00260 Glycine, serine and threonine metabolism 9
hsa00220 Arginine biosynthesis 4
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu00270 Cysteine and methionine metabolism 25
mmu01230 Biosynthesis of amino acids 14
mmu01200 Carbon metabolism 10
mmu01240 Biosynthesis of cofactors 9
mmu00260 Glycine, serine and threonine metabolism 9
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno00270 Cysteine and methionine metabolism 23
rno01230 Biosynthesis of amino acids 11
rno00260 Glycine, serine and threonine metabolism 10
rno01200 Carbon metabolism 9
rno00250 Alanine, aspartate and glutamate metabolism 5
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga00270 Cysteine and methionine metabolism 11
gga01230 Biosynthesis of amino acids 10
gga01200 Carbon metabolism 8
gga00260 Glycine, serine and threonine metabolism 5
gga00330 Arginine and proline metabolism 4
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dre00270 Cysteine and methionine metabolism 23
dre01230 Biosynthesis of amino acids 14
dre01200 Carbon metabolism 9
dre00260 Glycine, serine and threonine metabolism 7
dre01240 Biosynthesis of cofactors 6
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dme00270 Cysteine and methionine metabolism 14
dme01200 Carbon metabolism 7
dme01230 Biosynthesis of amino acids 7
dme00260 Glycine, serine and threonine metabolism 6
dme00250 Alanine, aspartate and glutamate metabolism 5
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cel00270 Cysteine and methionine metabolism 27
cel01230 Biosynthesis of amino acids 17
cel01200 Carbon metabolism 13
cel01240 Biosynthesis of cofactors 9
cel00260 Glycine, serine and threonine metabolism 6
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc00270 Cysteine and methionine metabolism 17
mcc01230 Biosynthesis of amino acids 7
mcc01200 Carbon metabolism 6
mcc00260 Glycine, serine and threonine metabolism 6
mcc00620 Pyruvate metabolism 5
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa00270 Cysteine and methionine metabolism 14
cfa05208 Chemical carcinogenesis - reactive oxygen species 4
cfa01240 Biosynthesis of cofactors 4
cfa00190 Oxidative phosphorylation 3
cfa04714 Thermogenesis 3
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
sce00270 Cysteine and methionine metabolism 21
sce01230 Biosynthesis of amino acids 14
sce01240 Biosynthesis of cofactors 5
sce00920 Sulfur metabolism 5
sce01200 Carbon metabolism 5
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
spo00270 Cysteine and methionine metabolism 18
spo01230 Biosynthesis of amino acids 17
spo01210 2-Oxocarboxylic acid metabolism 8
spo01240 Biosynthesis of cofactors 7
spo01200 Carbon metabolism 6
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca00270 Cysteine and methionine metabolism 16
fca01200 Carbon metabolism 9
fca01230 Biosynthesis of amino acids 8
fca00260 Glycine, serine and threonine metabolism 5
fca00020 Citrate cycle (TCA cycle) 4
Gene list in the network
Symbol Function*
AFM afamin
ARG2 arginase 2
ATP5F1A ATP synthase F1 subunit alpha
ATP5F1B ATP synthase F1 subunit beta
BCAT1 branched chain amino acid transaminase 1
BHMT betaine--homocysteine S-methyltransferase
CTH cystathionine gamma-lyase
ECHS1 enoyl-CoA hydratase, short chain 1
GCLC glutamate-cysteine ligase catalytic subunit
GCLM glutamate-cysteine ligase modifier subunit
GOT1 glutamic-oxaloacetic transaminase 1
GOT2 glutamic-oxaloacetic transaminase 2
HADHB hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
LDHB lactate dehydrogenase B
MDH1 malate dehydrogenase 1
MPST mercaptopyruvate sulfurtransferase
PSPH phosphoserine phosphatase
TST thiosulfate sulfurtransferase
AHCYL1 adenosylhomocysteinase like 1
SDS serine dehydratase
BHMT2 betaine--homocysteine S-methyltransferase 2
PHGDH phosphoglycerate dehydrogenase
DMGDH dimethylglycine dehydrogenase
PSAT1 phosphoserine aminotransferase 1
ADI1 acireductone dioxygenase 1
AGXT2 alanine--glyoxylate aminotransferase 2
MRI1 methylthioribose-1-phosphate isomerase 1
GPT2 glutamic--pyruvic transaminase 2
SDSL serine dehydratase like
OVCA2 OVCA2 serine hydrolase domain containing
SRXN1 sulfiredoxin 1
LOC105378936 uncharacterized LOC105378936
Symbol Function*
Amd1 S-adenosylmethionine decarboxylase 1
Mat1a methionine adenosyltransferase I, alpha
Slc25a4 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
Bcat1 branched chain aminotransferase 1, cytosolic
Bcat2 branched chain aminotransferase 2, mitochondrial
Bhmt betaine-homocysteine methyltransferase
Cbs cystathionine beta-synthase
Dbt dihydrolipoamide branched chain transacylase E2
Gclc glutamate-cysteine ligase, catalytic subunit
Gclm glutamate-cysteine ligase, modifier subunit
Got1 glutamic-oxaloacetic transaminase 1, soluble
Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial
Gss glutathione synthetase
Ldhb lactate dehydrogenase B
Mdh2 malate dehydrogenase 2, NAD (mitochondrial)
Mdh1 malate dehydrogenase 1, NAD (soluble)
Nqo1 NAD(P)H dehydrogenase, quinone 1
Tst thiosulfate sulfurtransferase, mitochondrial
Txnrd1 thioredoxin reductase 1
Bhmt2 betaine-homocysteine methyltransferase 2
Oxct1 3-oxoacid CoA transferase 1
Dmgdh dimethylglycine dehydrogenase precursor
Srxn1 sulfiredoxin 1 homolog (S. cerevisiae)
Slc25a12 solute carrier family 25 (mitochondrial carrier, Aralar), member 12
Psph phosphoserine phosphatase
Sec14l4 SEC14-like lipid binding 4
Psat1 phosphoserine aminotransferase 1
Cth cystathionase (cystathionine gamma-lyase)
Gpt2 glutamic pyruvate transaminase (alanine aminotransferase) 2
Etnk2 ethanolamine kinase 2
Gls2 glutaminase 2 (liver, mitochondrial)
Kyat3 kynurenine aminotransferase 3
Sds serine dehydratase
Mat2a methionine adenosyltransferase II, alpha
Tat tyrosine aminotransferase
Phgdh 3-phosphoglycerate dehydrogenase
Mpst mercaptopyruvate sulfurtransferase
Sdsl serine dehydratase-like
Symbol Function*
Agt angiotensinogen
Cbs cystathionine beta synthase
Got1 glutamic-oxaloacetic transaminase 1
Mdh1 malate dehydrogenase 1
Tat tyrosine aminotransferase
Cth cystathionine gamma-lyase
Sds serine dehydratase
Tst thiosulfate sulfurtransferase
Gclc glutamate-cysteine ligase, catalytic subunit
Mat1a methionine adenosyltransferase 1A
Asns asparagine synthetase (glutamine-hydrolyzing)
Atp1b1 ATPase Na+/K+ transporting subunit beta 1
Got2 glutamic-oxaloacetic transaminase 2
Gclm glutamate cysteine ligase, modifier subunit
Phgdh phosphoglycerate dehydrogenase
Atp5f1a ATP synthase F1 subunit alpha
Bhmt betaine-homocysteine S-methyltransferase
Cdo1 cysteine dioxygenase type 1
Mdh2 malate dehydrogenase 2
Agxt2 alanine-glyoxylate aminotransferase 2
Akr7a2 aldo-keto reductase family 7, member A2
Mpst mercaptopyruvate sulfurtransferase
Dmgdh dimethylglycine dehydrogenase
Mri1 methylthioribose-1-phosphate isomerase 1
Psat1 phosphoserine aminotransferase 1
Nnmt nicotinamide N-methyltransferase
Psph phosphoserine phosphatase
Kyat1 kynurenine aminotransferase 1
Sdsl serine dehydratase-like
Bhmt2 betaine-homocysteine S-methyltransferase 2
Kyat3 kynurenine aminotransferase 3
Aldh4a1 aldehyde dehydrogenase 4 family, member A1
Etnppl ethanolamine-phosphate phospho-lyase
Symbol Function*
GOT1 glutamic-oxaloacetic transaminase 1
GOT2 glutamic-oxaloacetic transaminase 2
GPT2 glutamic--pyruvic transaminase 2
UQCRC1 ubiquinol-cytochrome c reductase core protein 1
MDH2 malate dehydrogenase 2
PSPH phosphoserine phosphatase
MPST mercaptopyruvate sulfurtransferase
TST thiosulfate sulfurtransferase
CBSL cystathionine-beta-synthase like
MDH1 malate dehydrogenase 1
MAT1A methionine adenosyltransferase 1A
ALDH18A1 aldehyde dehydrogenase 18 family member A1
PHGDH phosphoglycerate dehydrogenase
CTH cystathionine gamma-lyase
OAT ornithine aminotransferase
PSAT1 phosphoserine aminotransferase 1
MGARP mitochondria localized glutamic acid rich protein
Symbol Function*
ldhba lactate dehydrogenase Ba
hgd homogentisate 1,2-dioxygenase
cbsb cystathionine beta-synthase b
phgdh phosphoglycerate dehydrogenase
cth cystathionase (cystathionine gamma-lyase)
bhmt betaine-homocysteine methyltransferase
arg2 arginase 2
gclc glutamate-cysteine ligase, catalytic subunit
immt inner membrane protein, mitochondrial (mitofilin)
psat1 phosphoserine aminotransferase 1
gclm glutamate-cysteine ligase, modifier subunit
mat1a methionine adenosyltransferase I, alpha
mdh1ab malate dehydrogenase 1Ab, NAD (soluble)
got2b glutamic-oxaloacetic transaminase 2b, mitochondrial
bcat1 branched chain amino-acid transaminase 1, cytosolic
slc1a4 solute carrier family 1 member 4
mtr 5-methyltetrahydrofolate-homocysteine methyltransferase
pah phenylalanine hydroxylase
cdo1 cysteine dioxygenase, type I
ahcyl2b adenosylhomocysteinase like 2b
mdh1aa malate dehydrogenase 1Aa, NAD (soluble)
got1 glutamic-oxaloacetic transaminase 1, soluble
mdh2 malate dehydrogenase 2, NAD (mitochondrial)
got2a glutamic-oxaloacetic transaminase 2a, mitochondrial
me2 malic enzyme 2, NAD(+)-dependent, mitochondrial
cbsa cystathionine beta-synthase a
atp5fa1 ATP synthase F1 subunit alpha
tat tyrosine aminotransferase
agxt2 alanine--glyoxylate aminotransferase 2
mat2ab methionine adenosyltransferase II, alpha b
Symbol Function*
Shmt Serine hydroxymethyl transferase
CG11134 uncharacterized protein
Ahcy Adenosylhomocysteinase
Cbs Cystathionine beta-synthase
Got2 Glutamate oxaloacetate transaminase 2
Mdh1 Malate dehydrogenase 1
CG6287 uncharacterized protein
Glo1 Glyoxalase 1
Echs1 Enoyl-CoA hydratase, short chain 1
Got1 Glutamate oxaloacetate transaminase 1
Mtap Methylthioadenosine phosphorylase
Eip55E Ecdysone-induced protein 55E
CG11241 uncharacterized protein
CG8132 uncharacterized protein
Kyat Kynurenine aminotransferase
AdSL Adenylosuccinate Lyase
CG11334 uncharacterized protein
Pgm1 Phosphoglucose mutase 1
CG11899 uncharacterized protein
Adi1 Acireductone dioxygenase 1
Symbol Function*
E01A2.1 GCS light chain
T09B4.8 Uncharacterized protein
ahcy-1 Adenosylhomocysteinase
F26H9.5 putative phosphoserine aminotransferase
atp-1 ATP synthase subunit alpha, mitochondrial
B0228.7 S-methyl-5'-thioadenosine phosphorylase
mthf-1 putative methylenetetrahydrofolate reductase
enol-1 Enolase
gcs-1 Glutamate--cysteine ligase
mtrr-1 Methionine synthase reductase
gss-1 Glutathione synthetase
ZK1307.1 Uncharacterized protein
metr-1 putative methionine synthase
ldh-1 L-lactate dehydrogenase
C31C9.2 Uncharacterized protein
cysl-2 Bifunctional L-3-cyanoalanine synthase/cysteine synthase
mdh-2 putative malate dehydrogenase, mitochondrial
hpd-1 4-hydroxyphenylpyruvate dioxygenase
aldo-1 Fructose-bisphosphate aldolase 1
sams-4 putative S-adenosylmethionine synthase 4
sams-3 putative S-adenosylmethionine synthase 3
adk-1 Adenosine kinase
gspd-1 Glucose-6-phosphate 1-dehydrogenase
Y62E10A.13 O-phosphoserine phosphohydrolase
sqrd-1 Pyr_redox_2 domain-containing protein
mdh-1 Malate dehydrogenase
C01G10.9 Methylthioribose-1-phosphate isomerase
cdo-1 Cysteine dioxygenase 1
dpyd-1 Dihydropyrimidine dehydrogenase [NADP(+)]
cysl-1 Cysteine synthase 1
cbs-1 PALP domain-containing protein
sams-1 putative S-adenosylmethionine synthase 1
bcat-1 Branched-chain-amino-acid aminotransferase, cytosolic
tatn-1 Tyrosine aminotransferase
got-1.2 Aspartate aminotransferase, cytoplasmic
F30F8.5 Uncharacterized protein
cbs-2 Cystathionine Beta-Synthase
cysl-4 Cysteine synthase
T13G4.4 Hcy-binding domain-containing protein
best-25 Bestrophin homolog 25
nit-1 CN hydrolase domain-containing protein
cysl-3 Cysteine synthase 3
Symbol Function*
LDHC lactate dehydrogenase C
KYAT3 kynurenine aminotransferase 3
LDHA lactate dehydrogenase A
MDH1 malate dehydrogenase 1
CDO1 cysteine dioxygenase type 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
AHCYL1 adenosylhomocysteinase like 1
HSD17B13 hydroxysteroid 17-beta dehydrogenase 13
ATP5F1A ATP synthase F1 subunit alpha
PSAT1 phosphoserine aminotransferase 1
WASHC5 WASH complex subunit 5
GOT1 glutamic-oxaloacetic transaminase 1
DMGDH dimethylglycine dehydrogenase
GCLC glutamate-cysteine ligase catalytic subunit
PHGDH phosphoglycerate dehydrogenase
BHMT2 betaine--homocysteine S-methyltransferase 2
BHMT betaine--homocysteine S-methyltransferase
SHMT2 serine hydroxymethyltransferase 2
PYCR1 pyrroline-5-carboxylate reductase 1
PDCL3 phosducin like 3
APIP APAF1 interacting protein
GLO1 glyoxalase I
MDH2 malate dehydrogenase 2
ADI1 acireductone dioxygenase 1
CBS cystathionine beta-synthase
ENOPH1 enolase-phosphatase 1
Symbol Function*
ATP5F1B ATP synthase F1 subunit beta
CYP2E1 cytochrome P450 family 2 subfamily E member 1
MPST mercaptopyruvate sulfurtransferase
MDH1 malate dehydrogenase 1
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
ATP5F1C ATP synthase F1 subunit gamma
GOT2 glutamic-oxaloacetic transaminase 2
SLC27A2 solute carrier family 27 member 2
BHMT betaine--homocysteine S-methyltransferase
TAT tyrosine aminotransferase
TST thiosulfate sulfurtransferase
AMD1 adenosylmethionine decarboxylase 1
PANK1 pantothenate kinase 1
GOT1 glutamic-oxaloacetic transaminase 1
BHMT2 betaine--homocysteine S-methyltransferase 2
DMGDH dimethylglycine dehydrogenase
SERPINA4 serpin family A member 4
MAT1A methionine adenosyltransferase 1A
GCLC glutamate-cysteine ligase catalytic subunit
GCLM glutamate-cysteine ligase modifier subunit
AGXT2 alanine--glyoxylate aminotransferase 2
ADI1 acireductone dioxygenase 1
NAA50 N-alpha-acetyltransferase 50, NatE catalytic subunit
Symbol Function*
MHT1 S-adenosylmethionine-homocysteine S-methyltransferase MHT1
YLR179C uncharacterized protein
SAM1 methionine adenosyltransferase SAM1
MET17 bifunctional cysteine synthase/O-acetylhomoserine aminocarboxypropyltransferase MET17
CYS3 cystathionine gamma-lyase CYS3
MDH3 malate dehydrogenase MDH3
KGD2 alpha-ketoglutarate dehydrogenase KGD2
HOM2 aspartate-semialdehyde dehydrogenase
MET32 Met32p
SAM2 methionine adenosyltransferase SAM2
ARO4 3-deoxy-7-phosphoheptulonate synthase ARO4
STR3 cystathionine beta-lyase STR3
CYS4 cystathionine beta-synthase CYS4
GSH1 glutamate--cysteine ligase
BNA3 kynurenine--oxoglutarate transaminase
MET3 sulfate adenylyltransferase
MET5 sulfite reductase (NADPH) subunit beta
MDH1 malate dehydrogenase MDH1
MET22 3'(2'),5'-bisphosphate nucleotidase
GSH2 glutathione synthase
SER33 phosphoglycerate dehydrogenase SER33
MET28 Met28p
ADI1 acireductone dioxygenase (Ni2+-requiring)
ILV2 acetolactate synthase catalytic subunit
MET2 homoserine O-acetyltransferase
SAM4 S-adenosylmethionine-homocysteine S-methyltransferase SAM4
MRI1 S-methyl-5-thioribose-1-phosphate isomerase MRI1
MUP3 Mup3p
BAT1 branched-chain-amino-acid transaminase BAT1
MXR1 peptide-methionine-S-sulfoxide reductase
SAH1 adenosylhomocysteinase
HOM3 aspartate kinase
MET6 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase
Symbol Function*
arg1 acetylornithine aminotransferase
SPCC569.07 putative aromatic aminotransferase
SPCC11E10.01 putative cystathionine beta-lyase
SPCC1827.06c putative aspartate semialdehyde dehydrogenase
SPCC364.07 putative D-3 phosphoglycerate dehydrogenase
sam1 S-adenosylmethionine synthetase
SPBC19F5.04 putative aspartate kinase
SPBC18E5.01 cycloisomerase 2 family
eca39 branched chain amino acid aminotransferase Eca39
SPBC428.11 homocysteine synthase Met17
arg12 putative argininosuccinate synthase
SPBC725.01 putative aspartate aminotransferase
SPBC839.16 C1-5,6,7,8-tetrahydrofolate (THF) synthase
SPBC8D2.18c putative adenosylhomocysteinase
SPBC8E4.03 putative agmatinase 2
spe2 S-adenosylmethionine decarboxylase proenzyme Spe2
lys3 saccharopine dehydrogenase Lys3
gpd2 glycerol-3-phosphate dehydrogenase Gpd2
gcs1 glutamate-cysteine ligase Gcs1
SPAC1F12.07 putative phosphoserine aminotransferase
SPAC24C9.12c putative glycine hydroxymethyltransferase
met16 phosphoadenosine phosphosulfate reductase
gsa1 glutathione synthetase large subunit Gsa1
SPAC10F6.13c putative aspartate aminotransferase
SPAC56E4.03 putative aromatic aminotransferase
SPAC922.03 putative 1-aminocyclopropane-1-carboxylate deaminase
met26 homocysteine methyltransferase Met26
SPNCRNA.1358
Symbol Function*
MDH1 malate dehydrogenase 1
CS citrate synthase
GCLM glutamate-cysteine ligase modifier subunit
PSPH phosphoserine phosphatase
NTHL1 nth like DNA glycosylase 1
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
MDH2 malate dehydrogenase 2
BHMT2 betaine--homocysteine S-methyltransferase 2
GOT1 glutamic-oxaloacetic transaminase 1
BHMT betaine--homocysteine S-methyltransferase
AHCYL2 adenosylhomocysteinase like 2
MARCHF5 membrane associated ring-CH-type finger 5
AHCY adenosylhomocysteinase
PHGDH phosphoglycerate dehydrogenase
DMGDH dimethylglycine dehydrogenase
GOT2 glutamic-oxaloacetic transaminase 2
SLC1A5 solute carrier family 1 member 5
LDHB lactate dehydrogenase B
DNMT3B DNA methyltransferase 3 beta
LOC101095082 methylthioribose-1-phosphate isomerase
PSAT1 phosphoserine aminotransferase 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
GCLC glutamate-cysteine ligase catalytic subunit
STOX1 storkhead box 1
VDAC1 voltage dependent anion channel 1
IDH3B isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
MRI1 methylthioribose-1-phosphate isomerase 1


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