[←][→] hsa  CYP3A7 Gene
functional annotation
Function   cytochrome P450 family 3 subfamily A member 7  
GO BP
GO:0002933 [list] [network] lipid hydroxylation  (7 genes)  IDA  
GO:0070989 [list] [network] oxidative demethylation  (19 genes)  IBA  
GO:0042573 [list] [network] retinoic acid metabolic process  (32 genes)  IDA  
GO:0008210 [list] [network] estrogen metabolic process  (39 genes)  IDA  
GO:0042572 [list] [network] retinol metabolic process  (48 genes)  IEA  
GO:0006805 [list] [network] xenobiotic metabolic process  (114 genes)  TAS  
GO:0006694 [list] [network] steroid biosynthetic process  (124 genes)  IEA  
GO:0008202 [list] [network] steroid metabolic process  (259 genes)  IBA IDA  
GO CC
GO:0005789 [list] [network] endoplasmic reticulum membrane  (1133 genes)  TAS  
GO MF
GO:0062183 [list] [network] all-trans retinoic acid 18-hydroxylase activity  (2 genes)  IEA  
GO:0050649 [list] [network] testosterone 6-beta-hydroxylase activity  (4 genes)  IBA  
GO:0101021 [list] [network] estrogen 2-hydroxylase activity  (5 genes)  IDA  
GO:0101020 [list] [network] estrogen 16-alpha-hydroxylase activity  (8 genes)  IBA IDA  
GO:0008401 [list] [network] retinoic acid 4-hydroxylase activity  (9 genes)  IDA  
GO:0070330 [list] [network] aromatase activity  (25 genes)  IEA  
GO:0008395 [list] [network] steroid hydroxylase activity  (37 genes)  IBA IDA  
GO:0019825 [list] [network] oxygen binding  (39 genes)  TAS  
GO:0004497 [list] [network] monooxygenase activity  (101 genes)  ISS  
GO:0020037 [list] [network] heme binding  (139 genes)  IEA  
GO:0005506 [list] [network] iron ion binding  (151 genes)  IEA  
KEGG hsa00140 [list] [network] Steroid hormone biosynthesis (61 genes)
hsa00830 [list] [network] Retinol metabolism (68 genes)
hsa05204 [list] [network] Chemical carcinogenesis - DNA adducts (69 genes)
Protein NP_000756.3 
BLAST NP_000756.3 
Orthologous [Ortholog page] CYP3A4 (hsa)  CYP3A5 (hsa)  TBXAS1 (hsa)  Cyp3a11 (mmu)  Cyp3a13 (mmu)  Cyp3a16 (mmu)  Tbxas1 (mmu)  Tbxas1 (rno)  Cyp3a23-3a1 (rno)  Cyp6v1 (dme)  Cyp6t1 (dme)  Cyp309a2 (dme)  Cyp28d1 (dme)  Cyp310a1 (dme)  Cyp6w1 (dme)  Cyp6a2 (dme)  Cyp6u1 (dme)  Cyp9b1 (dme)  Cyp9b2 (dme)  Cyp6a14 (dme)  Cyp6a13 (dme)  Cyp6g1 (dme)  Cyp6g2 (dme)  Cyp6t3 (dme)  Cyp9h1 (dme)  Cyp6a23 (dme)  Cyp6a19 (dme)  Cyp6a9 (dme)  Cyp6a20 (dme)  Cyp6a21 (dme)  Cyp6a8 (dme)  Cyp317a1 (dme)  Cyp6d2 (dme)  Cyp9c1 (dme)  Cyp9f2 (dme)  Cyp6d5 (dme)  Cyp6d4 (dme)  Cyp6a18 (dme)  Cyp6a17 (dme)  Cyp6a22 (dme)  Cyp3a41a (mmu)  Cyp3a25 (mmu)  CYP3A43 (hsa)  Cyp3a62 (rno)  Cyp3a9 (rno)  cyp-13A10 (cel)  cyp-25A2 (cel)  cyp-43A1 (cel)  cyp-13B1 (cel)  cyp-25A1 (cel)  cyp-13A11 (cel)  cyp-13A12 (cel)  cyp-25A6 (cel)  cyp-13B2 (cel)  cyp-13A4 (cel)  cyp-13A5 (cel)  cyp-13A6 (cel)  cyp-13A8 (cel)  cyp-13A3 (cel)  cyp-13A2 (cel)  cyp-13A1 (cel)  cyp-13A7 (cel)  Cyp3a18 (rno)  Cyp3a2 (rno)  cyp3c1 (dre)  Cyp3a44 (mmu)  CYP3A5 (gga)  CYP3A26 (cfa)  CYP3A12 (cfa)  CYP3A4 (gga)  TBXAS1 (gga)  CYP3A4 (cfa)  TBXAS1 (cfa)  LOC489851 (cfa)  cyp3c3 (dre)  Cyp3a73 (rno)  cyp3a65 (dre)  cyp3c2 (dre)  cyp3c4 (dre)  Cyp3a57 (mmu)  CYP3A4 (mcc)  CYP3A5 (mcc)  Cyp3a71-ps (rno)  CYP3A43 (mcc)  TBXAS1 (mcc)  tbxas1 (dre)  ERG5 (sce)  SPBC887.12 (spo)  SPAC24B11.12c (spo)  SPAC4F10.16c (spo)  SPAC821.13c (spo)  Cyp9f3 (dme)  cyp-25A3 (cel)  Cyp6a16 (dme)  Cyp3a41b (mmu)  Cyp3a59 (mmu)  CYP3A7 (mcc)  CYP3A132 (fca)  CYP3A131 (fca)  CYP3A7-CYP3A51P (hsa)  TBXAS1 (fca)  LOC102901745 (fca)  LOC103691023 (rno)  LOC106997572 (mcc)  LOC119868939 (cfa)  LOC119869229 (cfa)  LOC119875773 (cfa)  LOC119876349 (cfa) 
Subcellular
localization
wolf
E.R. 6,  extr 2,  pero 1,  extr_plas 1  (predict for NP_000756.3)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa05204 Chemical carcinogenesis - DNA adducts 12
hsa00980 Metabolism of xenobiotics by cytochrome P450 9
hsa00982 Drug metabolism - cytochrome P450 9
hsa00830 Retinol metabolism 8
hsa00140 Steroid hormone biosynthesis 7
Genes directly connected with CYP3A7 on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
17.2 CYP3A5 cytochrome P450 family 3 subfamily A member 5 [detail] 43 1577
16.9 CYP3A4 cytochrome P450 family 3 subfamily A member 4 [detail] 54 1576
5.7 SULT2A1 sulfotransferase family 2A member 1 [detail] 0 6822
Coexpressed
gene list		 [Coexpressed gene list for CYP3A7]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 1551      
Refseq ID (protein) NP_000756.3 


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