Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4  CPA1  carboxypeptidase A1 
 hsa-r.6  CPA1  carboxypeptidase A1 
 hsa-m.7  CPA1  carboxypeptidase A1 
 hsa-m2.4  CPA1  carboxypeptidase A1 
 mcc-u.3  CPB2  carboxypeptidase B2 
 mmu-u.4  Cpa4  carboxypeptidase A4 
 gga-u.3  CPA5  carboxypeptidase A5 
 gga-u.3  CPA6  carboxypeptidase A6 
 gga-u.3  CPO  carboxypeptidase O 
 dre-u.3  cpo  carboxypeptidase O 
 dre-u.3  cpb2  carboxypeptidase B2 (plasma) 
 dme-u.3  CG2915  uncharacterized protein 
 dme-u.3  CG4017  uncharacterized protein 
 cel-u.3  Y59C2A.1  Peptidase_M14 domain-containing protein 
 cel-u.3  W01A8.6  Peptidase_M14 domain-containing protein 
 cel-u.3  T06A4.3  Peptidase_M14 domain-containing protein;ShKT domain-containing protein 
 sce-u.3  ECM14  putative metallocarboxypeptidase 

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Top 50 coexpressed genes to CPA1 (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa4972   Pancreatic secretion  7 86 6.68
 hsa4974   Protein digestion and absorption  6 86 6.68
 hsa4022   cGMP-PKG signaling pathway  5 144 4.16
 hsa4261   Adrenergic signaling in cardiomyocytes  4 127 3.25
 hsa4260   Cardiac muscle contraction  3 67 2.97

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hsa:CPA1 (carboxypeptidase A1) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID
Other ID CoexPub LINK Target Reference

hsa-u.4
for
CPA1


hsa-r.6
for
CPA1


hsa-m.7
for
CPA1


hsa-m2.4
for
CPA1


mcc-u.3
for
CPB2


mmu-u.4
for
Cpa4


gga-u.3
for
CPA5


gga-u.3
for
CPA6


gga-u.3
for
CPO


dre-u.3
for
cpo


dre-u.3
for
cpb2


dme-u.3
for
CG2915


dme-u.3
for
CG4017


cel-u.3
for
Y59C2A.1


cel-u.3
for
W01A8.6


cel-u.3
for
T06A4.3


sce-u.3
for
ECM14

1 CPA2 carboxypeptidase A2 1358 27 7.5 10.3
2.4
2.9
1.1
3.4
1.0
10.4
7.5
0.2
-0.1
2.4
2.3
2.2
2.2
2.0
1.1
1.3
0.6
1.8
1.1
4.9
1.4
4.9
3.7
5.2
5.0

2 CTRB2 chymotrypsinogen B2 440387 7 6.0 7.3
1.9
3.2
-0.8
0.3
0.1
2.2
-1.5
0.0
3.5
2.9
0.7
0.7






3 INS insulin 3630 0 5.1 5.1
1.8


1.6
0.8



0.6
1.0






4 SYCN syncollin 342898 0 5.0 5.5
1.0
3.4

-0.9
1.3
-0.6
-0.1
1.4
0.7






5 CELA3A chymotrypsin like elastase 3A 10136 4 5.0 6.7
2.7
2.1

-0.6
-0.7
4.4
3.9
0.0
-0.1
0.5
0.5
2.8
2.5
2.1
1.2


0.7
0.8
-0.7

6 SLC22A8 solute carrier family 22 member 8 9376 0 4.8 4.7
1.5
3.7
2.4
1.9
1.7
1.3
1.3
0.8
0.6
0.6
2.8
2.0
3.7
2.8
3.4
2.6
2.7
2.1
2.4
2.0
1.6
1.6
2.7
2.2
2.9
1.6

7 CLPS colipase 1208 0 4.6 5.6
1.3
2.4

-0.9
3.4
-1.6
0.5








8 CELA3B chymotrypsin like elastase 3B 23436 0 4.5 5.2
3.3
2.7

-0.6
-0.7
4.4
3.9
0.0
-0.1
0.5
0.5
2.8
2.5
2.1
1.2


0.7
0.8
-0.7

9 MYL3 myosin light chain 3 4634 0 4.4 3.3
0.8
4.4
1.1
0.6
1.5
0.8
0.5
-0.4
-0.0
-0.1
0.8
0.5
1.6
1.6
2.0
0.5
2.9
-0.6
-0.1
-0.5
2.4
-0.1
0.9
-0.1
0.8
0.4
0.7
10 COPG2IT1 COPG2 imprinted transcript 1 53844 0 4.4 4.4
0.7














11 CELA2A chymotrypsin like elastase 2A 63036 0 4.3 5.1
2.6
2.5

-0.6
-0.7
4.4
3.9
0.0
-0.1
0.5
0.5
2.8
2.5
2.1
1.2


0.7
0.8
-0.7

12 MYL7 myosin light chain 7 58498 0 4.3 3.3
-0.1
4.2
0.4
0.3
0.7
0.6
0.5
0.0
0.1
-0.1
1.6
1.0
2.5
1.3
2.6
0.5
1.7
-0.2
0.5
2.0
1.2
0.3
0.1
0.4
-0.3

13 CTRB1 chymotrypsinogen B1 1504 4 4.1 6.5

0.8
-0.8
0.3
0.1
2.2
-1.5
0.0
3.5
2.9
0.7
0.7






14 CPA4 carboxypeptidase A4 51200 0 4.1 5.8
0.6
1.5
1.1
3.4
1.0
10.4
7.5
0.2
-0.1
2.4
2.3
2.2
2.2
2.0
1.1
1.3
0.6
1.8
1.1
4.9
1.4
4.9
3.7
5.2
5.0

15 TNP1 transition protein 1 7141 0 4.1 3.6
1.0
3.6
0.6
-0.4











16 MYH6 myosin heavy chain 6 4624 0 4.0 3.6
3.6
3.3
1.2
0.9
2.9
1.8
1.4
1.3
1.0
0.2
1.4
1.0
2.3
1.5
1.5
1.5
1.8
0.2
0.4
-0.2
1.7
1.6
1.9
1.0
0.9
0.7
-1.3
-1.6
17 IGFN1 immunoglobulin like and fibronectin type III domain containing 1 91156 0 3.9 3.1
2.1
3.8


0.6
-0.8
0.3
-0.1
-0.2
0.1
-0.8






18 MEST mesoderm specific transcript 4232 0 3.9 5.4
0.9
1.4
-0.5
2.9
1.3
-0.1
0.8
-0.5
0.3






19 CRB2 crumbs cell polarity complex component 2 286204 0 3.8 2.5
0.5
4.2
-0.4
1.4











20 UMOD uromodulin 7369 0 3.8 4.3
0.3
2.4
-0.0
-0.1
-0.1
1.9
-0.9
-0.2
1.3
0.6
1.6
0.9






21 MYOG myogenin 4656 0 3.8 4.1
-0.7
2.6
0.1
4.4
3.5
2.2
0.8
0.1
-0.5
0.7
-0.3
0.4
-1.0
0.4
-0.1
-0.9
0.8
1.0
0.8
0.6

22 LRRC10 leucine rich repeat containing 10 376132 0 3.7 3.5

3.1

0.0
1.5
-0.4
1.0
-0.2
3.1






23 DPEP1 dipeptidase 1 1800 0 3.7 2.2
1.5
4.3
-1.0
-0.4
1.0
0.7
1.0
4.5
-0.1
0.7
-0.4
0.9
0.5




24 LEP leptin 3952 0 3.7 2.5
0.4
4.0
0.4
0.8











25 CACNA1S calcium voltage-gated channel subunit alpha1 S 779 0 3.6 3.1
0.9
3.3
1.1
0.5
1.5
0.5
1.4
1.2
0.9
0.8
1.5
0.7
0.8
0.5
0.6
0.4
-0.9
-1.4
0.4
-0.4
0.6
-0.4
-0.2
-1.3
0.5
-0.0

26 SLC22A11 solute carrier family 22 member 11 55867 0 3.6 3.2
1.2
3.2
2.4
1.9
1.7
1.3
1.3
0.8
0.6
0.6
2.8
2.0
3.7
2.8
3.4
2.6
2.7
2.1
2.4
2.0
1.6
1.6
2.7
2.2
2.9
1.6

27 H1-8 H1.8 linker histone 132243 0 3.6 2.8
1.2
3.6
0.6
-0.5
1.5
-0.7
0.5
-1.4
-0.5






28 DBH dopamine beta-hydroxylase 1621 0 3.6 2.4
1.4
4.0
1.1
2.4
0.6
-0.8
-0.2
0.4
0.1
-0.7
-0.7
1.2
-1.2
-0.1

29 LRRN4 leucine rich repeat neuronal 4 164312 0 3.6 3.1
2.3
3.2
1.2
-1.2
0.5
-0.1
0.4
0.1
0.2






30 KRT71 keratin 71 112802 0 3.6 4.7
-0.5
1.5
1.8
0.6
8.9
6.8
1.9
1.6
1.1
0.7
1.4
1.3
3.5
0.7
0.5
0.4






31 GP2 glycoprotein 2 2813 0 3.5 3.6
1.9
2.6
-0.0
-0.1
-0.1
1.9
-0.9
-0.2
1.3
0.6
1.6
0.9






32 TNNI1 troponin I1, slow skeletal type 7135 0 3.5 2.0
2.3
4.2
-0.4
-0.6
1.2
0.7
-0.4
-0.7
-0.5
-0.8
-0.7
-1.5
2.0
1.5
1.1
0.6
-0.9
-0.2
3.2
1.4
0.8
0.7
0.7
0.5

33 TMEM132C transmembrane protein 132C 92293 0 3.5 2.7
-0.0
3.4
0.2
0.1
0.8
0.8
-0.0
-0.9
2.1
0.4
0.2
0.0
0.9
0.8
0.1
0.0
-0.8
-0.9
1.4
1.1
0.9

34 REG3G regenerating family member 3 gamma 130120 0 3.4 5.9
2.6
0.1

0.5
0.3
1.3
-0.5
0.3


0.4
-0.5
0.3
-1.9
-0.4

35 KLHL30 kelch like family member 30 377007 0 3.4 2.2

3.8

1.4
0.3
-0.3
0.1
-0.3
0.3






36 SERPINA4 serpin family A member 4 5267 0 3.4 2.8
1.0
3.2
1.2












37 C10orf71 chromosome 10 open reading frame 71 118461 0 3.4 4.2
2.0
1.8
0.7
0.7
-0.2
-1.3
-0.5
0.0
-0.4
0.6
0.6






38 BNIP5 BCL2 interacting protein 5 389384 0 3.4 1.3

4.6
-1.4
-1.0











39 PTPRQ protein tyrosine phosphatase receptor type Q 374462 0 3.4 3.4



1.4
-0.7
1.1
-0.1
0.6
-0.5






40 DLK1 delta like non-canonical Notch ligand 1 8788 0 3.4 3.4
1.0
2.5
0.8
2.6
0.2
0.4
-0.7
0.5
-0.1






41 GATA5 GATA binding protein 5 140628 0 3.4 2.3
2.3
3.6
1.7
1.7
0.3
-0.1
1.4
0.9
1.2
0.6
1.1
1.0
1.3
1.2
2.0
1.4
0.7
0.3
-0.1
-0.5
2.3
1.3
1.3
1.2
0.7
0.4
-0.1
-1.0
42 TNNT3 troponin T3, fast skeletal type 7140 0 3.3 3.0
1.0
2.8
-0.1
-0.7
1.2
-0.3
0.9
0.2
-0.2
-0.4
0.4
-0.2
-0.1
-0.5
0.3
0.2






43 HNF1A HNF1 homeobox A 6927 0 3.3 1.8
2.0
3.9
1.3
-1.2
0.7
-1.1
0.9
0.8
1.5






44 CALML3 calmodulin like 3 810 0 3.3 2.2
1.9
3.6
1.4
0.1
3.7
-0.6
-0.2
-0.2
0.6
0.5
0.2
-0.2
0.9
0.8
-0.1
-0.3
0.8
-0.5
1.2
-0.7
1.5

45 SLC22A6 solute carrier family 22 member 6 9356 0 3.3 3.8
2.1
2.0
2.4
1.9
1.7
1.3
1.3
0.8
0.6
0.6
2.8
2.0
3.7
2.8
3.4
2.6
2.7
2.1
2.4
2.0
1.6
1.6
2.7
2.2
2.9
1.6

46 RTL1 retrotransposon Gag like 1 388015 0 3.3 2.6

3.1

2.8
0.3
-0.5
0.4
-0.2
0.8
-0.4
0.9
0.3
0.8
0.6


-0.3
-0.2
-0.1
-0.2
-0.5
47 PNLIPRP1 pancreatic lipase related protein 1 5407 0 3.3 3.4
-0.1
2.3

1.2
0.4
4.2
1.5
-0.6
-1.0
0.8
0.3


-1.6
0.7




48 GATA4 GATA binding protein 4 2626 0 3.2 2.6
2.1
3.1
1.7
1.7
0.3
-0.1
1.4
0.9
1.2
0.6
1.1
1.0
1.3
1.2
2.0
1.4
0.7
0.3
-0.1
-0.5
2.3
1.3
1.3
1.2
0.7
0.4
-0.1
-1.0
49 INMT indolethylamine N-methyltransferase 11185 0 3.2 2.7
0.9
3.0
1.4
0.3
0.0
-0.7
0.3
-1.3
-0.6
0.4
1.0


2.4
0.3
1.3
0.9
0.6
0.2

50 ABCA4 ATP binding cassette subfamily A member 4 24 0 3.2 2.4
1.0
3.3
0.4
0.0
-0.5
-1.0
0.4
0.1
0.1
-0.5
-0.0
-0.0
2.3
0.7
0.6
-0.0


1.2
-1.6
0.5

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