Publication for CPA1 and CTRB1

Species Symbol Function* Entrez Gene ID* Other ID Gene
coexpression
CoexViewer
hsa CPA1 carboxypeptidase A1 1357 [link]
hsa CTRB1 chymotrypsinogen B1 1504

Pubmed ID Priority Text
29302047 0.98 CPA1 promoter-reporter construct and CTRB1 promoter-reporter construct.
0.95 CPA1 and CTRB1 promoter activity was observed when co-transfected with PTF1A alone (ESM Fig. 2), presumably due to endogenous expression of RBPJ in HEK293 cells.
0.91 CPA1 or CTRB1 promoter (ESM Fig. 2).
0.83 CPA1 and CTRB1 promoter activity, respectively, was observed when both RBPJL and PTF1A expression vectors were co-transfected with the promoter-reporter constructs compared to PTF1A alone (ESM Fig. 2).
0.74 CPA1 or CTRB1 promoter-reporter vector and either (1) RBPJL expression vector alone, (2) PTF1A expression vector alone, or (3) both RBPJL and PTF1A expression vectors.
0.69 CTRB1 and CPA1 promoters) to identify the difference in transactivation potential between RBPJL Thr280 and Met280 was done in HEK293 cells.
0.56 CPA1 and CTRB1 was assessed in Human Embryonic Kidney cells-293 (HEK-293).
0.54 CPA1 and CTRB1 promoters by normal (Thr280) RBPJL alone or in combination with PTF1A.
30420730 0.97 CPA1 variants in Chinese ICP patients, and the lack of any contribution of the CTRB1-CTRB2 risk allele to CP risk variation in the Chinese population due to allele near-fixation.
30789418 0.97 carboxypeptidase A1 (CPA1), and chymotrypsinogen B1 and B2 (CTRB1-CTRB2) have been found to predispose to or protect from CP.
30755276 0.95 CPA1 variants were not enriched in Chinese chronic pancreatitis patients; and the common CTRB1-CTRB2 inversion allele did not contribute to disease risk in the Chinese population due to near allele fixation.



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