Publication for CPA1 and CPA2

Species	Symbol	Function*	Entrez Gene ID*	Other ID	Gene coexpression	CoexViewer
hsa	CPA1	carboxypeptidase A1	1357			[link]
hsa	CPA2	carboxypeptidase A2	1358

Pubmed ID	Priority	Text
24449006	0.97	CPA1 and CPA2 phases.
	0.93	CPA1, and CPA2) are shown for the ESL (erector spinae longus), ST (semitendinosis), and GASM (medial gastrocnemius) muscles for young and older adults.
	0.90	CPA1 epoch and was then inhibited during the CPA2 epoch.
	0.60	CPA1 epoch in older adults was also significantly larger in magnitude than the CPA2 epoch in young adults (p = 0.02).
21778109	0.97	CPA 1 and CPA 2 epochs in both of these muscles (p<0.01).
	0.95	CPA1 and CPA2 intervals as compared to the no vision condition.
	0.66	CPA1 and CPA2) with its standard error bars.
28993202	0.97	CPA1, CPA2, CPB1, PNLIP, SYCN, CELA3A and AMY2A) proteins, directly from our global plasma proteomics data in spite of the high complexity of plasma proteome.
31644800	0.97	Complementary Package of Activities (CPA) 1 and CPA 2 hospitals but lower than the US$41.53 they reported for CPA 3 hospitals.
15998457	0.96	Cpa2 is dispensable for these functions in the presence of Cpa1.
	0.79	CPA1 and CPA2 genes leads to a conditional synthetic phenotype, resulting in a defect in growth and virulence.
	0.53	Cpa1 and Cpa2 is hypothesized to be independent of calcineurin function, suggesting a novel role for cyclophilin A homologs in the growth and virulence of this pathogen.
21631589	0.96	CPA1, CPA2 and CPB1 are secreted by the pancreas as inactive proenzymes containing a 94-96 amino-acid long propeptide.
	0.91	CPA1 or CPA2 genes should be also risk factors for chronic pancreatitis.
	0.89	CPA1 and CPA2.
27654405	0.96	CPA1 subfamily which includes the medically important mammalian NHE exchangers, and the CPA2 subfamily, which includes many bacterial antiporters (and only two human exchangers: NHA1-2).
	0.96	CPA1 members that were tested seem to be electroneutral, suggesting a 1:1 substrate ratio, whereas CPA2 members are electrogenic, with a measured ratio of 2:1 for some members.
	0.95	CPA1 and CPA2 members are strikingly similar.
23028731	0.96	CPA2, TSGA13, CPA1, C7orf45 and NYD-SP18 consistently showed high levels of methylation but low gene expression in each of the SMZL with 7 q deletion (Figure S4).
27152640	0.95	CPA1 and CPA2) the postural disturbances.
	0.94	CPA1 and CPA2) time intervals for the GM, EO and PE right and left lateral muscles for each group (average across 13 subjects).
	0.93	CPA1, i.e., just after the impact, was significantly higher than the time intervals for APA1, APA2 and CPA2 in all muscles for both groups (Fig 3).
	0.92	CPA1 and CPA2 (all post-hoc p values were below 0.001).
31470614	0.95	hCPA1 and hCPA4, the very low Ki values are in the picomolar range; for most of the subfamily members with a different enzymatic activity, i.e., CPB-type enzymes, they are in the order of 1 x 10-10 M; and a particular case stands for rCPA3 and for hCPA2 for which NvCI displays a Ki almost two or four orders of magnitude weaker than for hCPA1, respectively.
	0.80	CPA1 and CPA2 forms does not arise from their preference for the amino acid type but for their volume, as CPA2 prefers bulkier hydrophobic amino acids while CPA1 prefers smaller ones.
29290589	0.95	Cpa2 and Cpa1, carboxypeptidase A) or ER luminal chaperones and oxidoreductases (Hspa5, BiP; Pdia6 and P4hb, protein disulfide isomerases; Calr, Calreticulin).
29631213	0.94	CPA1, CPA2, CPB1, and CTRC expression in tumor and peritumoral tissues.
	0.89	CPA1, but not CPA2 and CPB1, are associated with CP.
	0.87	CPA1, CPA2, CPB1, and CTRC between tumor and peritumor tissues.
	0.81	carboxypeptidase A1 (CPA1), carboxypeptidase A2 (CPA2), carboxypeptidase B1 (CPB1), and chymotrypsin C (CTRC).
	0.59	CPA1, CPA2, CPB1, and CTRC in tumor and peritumoral tissues.
	0.55	CPA1: carboxypeptidase A1; CPA2: carboxypeptidase A2; CPB1: carboxypeptidase B1; CTRC: chymotrypsin C; RPS11: 40S ribosomal protein S11; RPL12: ribosomal protein L12; RPS18: 40S ribosomal protein S18; RPL35: ribosomal protein L35; RPL38: ribosomal protein L38; RPL8: ribosomal protein L8; PLEC: plectin 1; PARK7: Protein deglycase DJ-1; POSTN: periostin; THBS2: thrombospondin2; LUM: lumican; PRELP: proline/arginine-rich end leucine-rich repeat protein; NIN: ninein; ENO2: enolase2; and HSPA9: heat shock 70-kDa protein 9.
30950253	0.94	CPA1 is compared against aLL1 and aLL2, while Fig. 3A and B are quite different by 0.214, where CPA1 and CPA2 are compared against aLL1.
	0.67	CPA1 and aLL1, 0.564 (P < 0.01) between CPA1 and aLL2, 0.808 (P < 0.01) between CPA2 and aLL1, and 0.757 (P < 0.01) between CPA2 and aLL2 (Fig. 3).
27620696	0.93	CPA1, CPA2, and PNLIP (Figure 6) in acinar tissue compared to islets is in agreement with data from HPA and with previous studies on protein and gene expression levels.
25701605	0.92	CPA1, CPA2 and NaT-DC (Na+-transporting carboxylic acid decarboxylase) ( and).
25875328	0.92	CPA1, CPA2, CPA4, CPB1 and CPB2.
31448319	0.91	CPA #1 and CPA #2 or in the alginate hydrogel slice without any CPA during cooling and warming.
23955596	0.90	CPA1 and CPA2) act on aromatic and aliphatic amino acid residues exposed by the action of chymotrypsins and elastases, whereas the B-type carboxypeptidase (CPB1) hydrolyzes C-terminal Lys and Arg residues generated by tryptic cleavages.
21355996	0.89	cpa1 resulted in a reduction in virulence and an inability to grow at 39 C, whereas cpa2 was dispensable for both virulence and growth at 39 C. CYP1 (MgCYP1) of the rice blast fungus Magnaporthe grisea is required for the fungus to penetrate the leaf cuticle and to produce normal asexual spores.
	0.84	cpa1 and cpa2 confer CsA sensitivity in an independent manner.
	0.60	cpa1 cpa2 cyclophilin A double mutant and calcineurin mutants, including loss of virulence, and studies that indicate cyclophilin-mediated regulation of calcineurin in Saccharomyces cerevisiae.
24268589	0.89	CPA1 was significantly larger than CPA2 for all the muscles (p<0.01).
	0.70	CPA1 and CPA2 epochs with its standard error bars.
22198575	0.88	CPA1 and CPA2) with its standard error bars.
20156693	0.87	CPA1, CPA2) (Fig. 1).
	0.75	CPA1, and CPA2).
20616913	0.86	CPA 2% vs CPB 11%), increased bilirubin (18% vs 40%), and worsening ascites (CPA 11% vs CPB 18%) when treated with sorafenib.
20182389	0.85	carboxypeptidase A1, carboxypeptidase A2, chymotrypsinogen B1, chymotrypsinogen B2, chymotrypsin C, elastase, lipase, and trypsin.
31091671	0.84	CPA1, CPA2, and NaT-DC (Na-transporting carboxylic acid decarboxylase).
31397502	0.83	CPA1 and CPA2, respectively.20 MCP has been reported to be linked to tumorigenesis.
24473071	0.70	CPA1 transporters are electroneutral and most likely exchange protons and Na+ ions with a 1:1 stoichiometry, whereas CPA2 transporters, which mostly exchange two protons per Na+, are electrogenic.