Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4   PTTG1   PTTG1 regulator of sister chromatid separation, securin 
 hsa-r.6   PTTG1   PTTG1 regulator of sister chromatid separation, securin 
 hsa-m.7   PTTG1   PTTG1 regulator of sister chromatid separation, securin 
 hsa-m2.4   PTTG1   PTTG1 regulator of sister chromatid separation, securin 
 mcc-u.3   PTTG1   PTTG1 regulator of sister chromatid separation, securin 
 mmu-u.4   Pttg1   pituitary tumor-transforming gene 1 
 rno-u.3   Pttg1   PTTG1 regulator of sister chromatid separation, securin 
 cfa-u.3   PTTG1   PTTG1 regulator of sister chromatid separation, securin 
 gga-u.3   PTTG2   pituitary tumor-transforming 2 
 dre-u.3   pttg1   PTTG1 regulator of sister chromatid separation, securin 
 spo-u.3   mph1   dual-specificity protein kinase Mph1 

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Top 50 coexpressed genes to PTTG1 (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa4110   Cell cycle  8 119 7.21
 hsa4914   Progesterone-mediated oocyte maturation  7 80 6.86
 hsa4114   Oocyte meiosis  7 104 6.19
 hsa5166   Human T-cell leukemia virus 1 infection  4 206 2.47
 hsa5200   Pathways in cancer  4 531 -

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hsa:PTTG1 (PTTG1 regulator of sister chromatid separation, securin) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-u.4
for
PTTG1
hsa-r.6
for
PTTG1
hsa-m.7
for
PTTG1
hsa-m2.4
for
PTTG1
mcc-u.3
for
PTTG1
mmu-u.4
for
Pttg1
rno-u.3
for
Pttg1
cfa-u.3
for
PTTG1
gga-u.3
for
PTTG2
dre-u.3
for
pttg1
spo-u.3
for
mph1
1 CCNB1 cyclin B1 891 71 15.2 14.3
 6.5
 12.5
 8.8
8.2
 3.8
3.3
 12.7
12.6
 10.8
6.0
 13.2
11.1
 11.4
8.6
2 CCNB2 cyclin B2 9133 20 13.0 13.3
 5.5
 9.6
 8.8
8.2
 3.8
3.3
 12.7
12.6
 10.8
6.0
 13.2
11.1
 11.4
8.6
3 CDKN3 cyclin dependent kinase inhibitor 3 1033 14 11.8 13.2
 6.6
 7.5
 6.7
 3.7
 13.8
 4.5
 7.1
 2.2
4 KIF20A kinesin family member 20A 10112 8 11.4 12.3
 7.2
 7.7
 6.7
 2.4
 11.3
 6.1
 7.5
0.1
 6.8
6.1
5 TPX2 TPX2 microtubule nucleation factor 22974 19 11.2 12.5
 5.6
 7.2
 6.4
 3.0
 6.7
 7.7
 9.3
 8.7
6 CDC20 cell division cycle 20 991 62 10.5 12.0
 6.6
 6.4
 0.4
 2.7
2.6
 13.6
3.2
 8.3
1.4
 11.0
-0.2
 9.8
1.2
7 NUSAP1 nucleolar and spindle associated protein 1 51203 12 10.4 11.7
 4.8
 6.6
 5.5
 3.2
 13.0
9.6
 7.0
 1.1
8 DLGAP5 DLG associated protein 5 9787 10 10.3 10.5
 5.4
 7.6
 5.5
 2.1
 10.2
 10.4
 9.5
 7.3
9 UBE2C ubiquitin conjugating enzyme E2 C 11065 33 10.2 10.4
 5.2
 7.6
3.8
 15.2
 4.0
 11.5
 9.2
10 CENPW centromere protein W 387103 2 10.1 9.1
 4.2
 8.7
 5.3
 3.1
 12.1
 5.7
 9.8
 6.4
11 CDC25C cell division cycle 25C 995 5 10.1 10.8
 3.8
 7.0
 4.3
2.7
 3.1
2.8
 3.8
0.6
 5.1
2.2
 2.1
 6.4
 -0.5
12 BIRC5 baculoviral IAP repeat containing 5 332 24 9.9 10.9
 4.7
 6.5
 4.9
 3.3
 10.5
 9.4
 9.4
 7.9
2.7
13 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 699 18 9.8 9.8
 3.0
 7.4
 3.9
 1.0
 8.0
 6.6
 5.2
 6.6
 -1.8
14 KIF2C kinesin family member 2C 11004 2 9.7 11.2
 4.1
 5.9
 5.4
-0.2
 2.5
0.3
 11.2
-0.1
 3.3
1.4
 9.4
0.4
 1.3
-1.0
15 NEK2 NIMA related kinase 2 4751 12 9.5 9.5
 3.9
 7.3
 5.7
 2.2
 6.5
 8.4
 9.5
 7.9
16 CKS2 CDC28 protein kinase regulatory subunit 2 1164 6 9.4 11.0
 4.9
 5.6
 5.9
3.5
 3.5
1.8
 6.8
2.7
 6.1
5.9
 10.2
9.0
 5.5
4.4
17 PLK1 polo like kinase 1 5347 27 9.3 10.5
 3.3
 5.9
 4.8
1.6
 3.0
-0.0
 11.8
0.1
 7.9
0.2
 10.3
-1.4
 8.6
0.3
 1.4
18 ASPM assembly factor for spindle microtubules 259266 6 9.2 9.4
 4.0
 6.8
 5.0
6.8
 7.9
 6.4
 7.0
19 CENPF centromere protein F 1063 12 9.2 9.9
 4.2
 6.3
 6.9
 2.4
 9.7
 7.2
 7.5
 5.6
20 PRC1 protein regulator of cytokinesis 1 9055 21 9.2 9.3
 4.4
 6.8
 5.1
 2.5
 9.7
 7.4
 7.9
 7.9
6.7
 0.8
-0.1
21 RACGAP1 Rac GTPase activating protein 1 29127 9 9.0 10.0
 4.1
 5.7
 6.1
 1.7
 10.3
 8.5
 8.3
0.4
 6.7
-0.4
 2.0
1.8
22 CCNA2 cyclin A2 890 32 8.8 9.7
 4.2
 5.9
 6.2
-0.4
 1.9
 8.7
1.2
 8.0
 6.7
1.1
 11.1
1.0
 -1.5
23 HMMR hyaluronan mediated motility receptor 3161 7 8.8 10.0
 5.7
 5.5
 4.4
 2.8
 8.2
 5.7
 7.0
 6.0
24 TOP2A DNA topoisomerase II alpha 7153 23 8.8 9.0
 4.1
 6.5
 6.7
0.7
 1.2
-1.8
 10.8
-0.5
 8.5
0.5
 8.0
0.6
 6.2
0.8
 0.3
-1.0
25 NUF2 NUF2 component of NDC80 kinetochore complex 83540 4 8.8 9.5
 3.3
 6.0
 7.2
 1.9
 12.2
 8.4
 8.9
 4.8
 0.4
26 AURKA aurora kinase A 6790 33 8.7 9.5
 4.8
 5.7
 5.6
4.7
 3.8
1.6
 8.1
7.0
 8.1
4.2
 11.3
 6.9
6.0
27 CENPA centromere protein A 1058 1 8.6 9.3
 4.8
 5.9
 5.2
 4.8
 4.5
 6.5
 5.6
 4.9
28 KPNA2 karyopherin subunit alpha 2 3838 6 8.6 9.1
 3.2
 6.0
 2.6
-0.7
 2.4
0.3
 3.3
 5.0
 10.2
-0.7
 6.5
1.0
29 KIF4A kinesin family member 4A 24137 6 8.6 9.7
 4.4
 5.5
 5.1
 2.1
 7.7
 5.0
 8.5
 4.6
 2.1
30 SPAG5 sperm associated antigen 5 10615 1 8.6 9.2
 4.5
 5.9
 5.6
 3.0
 7.9
 8.0
 7.0
 7.4
31 AURKB aurora kinase B 9212 15 8.3 9.6
 2.7
 5.0
 5.6
4.7
 3.8
1.6
 8.1
7.0
 8.1
4.2
 11.3
 6.9
6.0
32 PBK PDZ binding kinase 55872 8 8.3 8.5
 4.0
 6.0
 1.7
 1.0
 9.5
 6.7
 9.9
 6.8
 0.6
33 CDCA3 cell division cycle associated 3 83461 5 8.2 9.0
 5.0
 5.4
 5.6
 3.2
 13.0
 8.3
 12.5

34 CEP55 centrosomal protein 55 55165 17 8.2 8.8
 3.8
 5.7
 3.8
 1.8
 8.0
 6.4
 6.0
 7.2
35 TROAP trophinin associated protein 10024 0 8.2 10.4
 4.1
 4.0
 4.3
 2.9
 8.3

4.5
36 MKI67 marker of proliferation Ki-67 4288 7 8.0 8.6
 3.9
 5.5
 5.5
 1.4
 9.7
 4.7
 6.7
 6.5
37 PRR11 proline rich 11 55771 0 7.9 7.6
 2.8
 6.2
 3.8
 1.9
 6.3
 5.0
 7.3
 6.5
38 NDC80 NDC80 kinetochore complex component 10403 6 7.9 8.0
 3.1
 5.8
 5.1
 1.7
 7.6
 7.2
 6.2
 7.6
39 BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 701 30 7.8 8.3
 3.5
 5.4
 4.9
 3.4
 11.5
 7.3
 10.6
 5.8
4.3
40 NCAPG non-SMC condensin I complex subunit G 64151 4 7.7 7.6
 3.1
 5.9
 6.1
 1.3
 5.6
 7.3
 6.9
 9.0
41 HJURP Holliday junction recognition protein 55355 1 7.7 8.5
 3.2
 5.0
 6.6
 2.1
0.7
 3.2
 5.9
 6.3

42 GTSE1 G2 and S-phase expressed 1 51512 1 7.7 8.2
 3.3
 5.3
 5.0
 2.0
 4.9
 6.8
 7.5
 4.1
43 CENPE centromere protein E 1062 5 7.6 8.7
 4.2
 4.7
 4.0
3.3
 2.5
1.6
 10.4
9.4
 6.2
3.6
 7.2
2.7
 7.9
5.0
44 CDCA8 cell division cycle associated 8 55143 9 7.6 9.4
 4.0
 3.9
 6.1
 3.1
 9.3
 5.6
7.1
45 KIF23 kinesin family member 23 9493 6 7.6 7.7
 2.3
 5.7
 5.6
 2.5
 7.0
 7.4
 6.3
 9.2
46 DEPDC1 DEP domain containing 1 55635 4 7.5 8.5
 4.0
 4.7
 4.9
 1.7
 9.3
 6.3
 7.2
 5.4
47 KIFC1 kinesin family member C1 3833 2 7.4 8.2
 1.6
 4.8
 4.0
3.3
 2.5
1.6
 10.4
9.4
 6.2
3.6
 7.2
2.7
 7.9
5.0
48 DEPDC1B DEP domain containing 1B 55789 0 7.3 6.8
 2.9
 6.1
 3.2
 2.0
 5.7
 5.0
 6.2
 2.6
49 CKS1B CDC28 protein kinase regulatory subunit 1B 1163 3 7.3 8.4
 2.8
 4.5
 5.9
3.5
 3.5
1.8
 6.8
2.7
 6.1
5.9
 10.2
9.0
 5.5
4.4
50 PIMREG PICALM interacting mitotic regulator 54478 0 7.2 8.9
 3.5
 3.8
 2.7
 1.9
 7.6
 3.6
 2.6

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