Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4   VARS1   valyl-tRNA synthetase 1 
 hsa-r.6   VARS1   valyl-tRNA synthetase 1 
 hsa-m.7   VARS1   valyl-tRNA synthetase 1 
 hsa-m2.4   VARS1   valyl-tRNA synthetase 1 
 hsa-u.4   VARS2   valyl-tRNA synthetase 2, mitochondrial 
 mcc-u.3   VARS2   valyl-tRNA synthetase 2, mitochondrial 
 mcc-u.3   VARS1   valyl-tRNA synthetase 1 
 mmu-u.4   Vars2   valyl-tRNA synthetase 2, mitochondrial 
 mmu-u.4   Vars   valyl-tRNA synthetase 
 rno-u.3   Vars2   valyl-tRNA synthetase 2, mitochondrial 
 rno-u.3   Vars1   valyl-tRNA synthetase 1 
 cfa-u.3   VARS2   valyl-tRNA synthetase 2, mitochondrial 
 cfa-u.3   VARS1   valyl-tRNA synthetase 1 
 gga-u.3   107049913   valine--tRNA ligase, mitochondrial-like 
 gga-u.3   107050659   valine--tRNA ligase-like 
 dre-u.3   vars2   valyl-tRNA synthetase 2, mitochondrial 
 dre-u.3   vars1   valyl-tRNA synthetase 1 
 dme-u.3   ValRS-m   Valyl-tRNA synthetase, mitochondrial 
 dme-u.3   ValRS   Valyl-tRNA synthetase 
 cel-u.3   glp-4   Valine--tRNA ligase 
 cel-u.3   vars-1   Valyl-tRNA synthetase 
 sce-u.3   VAS1   valine--tRNA ligase 
 spo-u.3   clp1   Cdc14 family protein phosphatase Clp1 

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Top 50 coexpressed genes to VARS1 (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa970   Aminoacyl-tRNA biosynthesis  4 43 5.09
 hsa3008   Ribosome biogenesis in eukaryotes  3 74 2.85
 hsa230   Purine metabolism  3 108 2.38
 hsa670   One carbon pool by folate  2 16 2.99
 hsa270   Cysteine and methionine metabolism  2 43 2.13

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hsa:VARS1 (valyl-tRNA synthetase 1) External Links;


Show/Hide Columns:          
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-u.4
for
VARS1
hsa-r.6
for
VARS1
hsa-m.7
for
VARS1
hsa-m2.4
for
VARS1
hsa-u.4
for
VARS2
mcc-u.3
for
VARS2
mcc-u.3
for
VARS1
mmu-u.4
for
Vars2
mmu-u.4
for
Vars
rno-u.3
for
Vars2
rno-u.3
for
Vars1
cfa-u.3
for
VARS2
cfa-u.3
for
VARS1
gga-u.3
for
107049913
gga-u.3
for
107050659
dre-u.3
for
vars2
dre-u.3
for
vars1
dme-u.3
for
ValRS-m
dme-u.3
for
ValRS
cel-u.3
for
glp-4
cel-u.3
for
vars-1
sce-u.3
for
VAS1
spo-u.3
for
clp1
1 IPO4 importin 4 79711 0 10.3 9.0
 3.3
 9.0
 2.8
 3.4
 5.7
 2.0
 6.4
 1.2
 8.0
 4.0
 6.2
 8.7
 7.4
 0.7
 5.6
 2.7
1.2
 4.3
1.3

5.9
2 WDR46 WD repeat domain 46 9277 0 10.1 10.1
 5.0
 7.6
 4.1
 1.0
 5.9
 2.5
 5.8
 2.2
 5.1
 3.4
 7.5

1.5
 3.4
 0.6
 2.0
 1.8
 4.7
 -0.2
 0.3
3 MYBBP1A MYB binding protein 1a 10514 0 9.5 9.5
 3.1
 7.3
 2.6
 3.2
 5.8
 2.0
 7.3
 2.3
 6.9
 3.2
 8.1
 -0.1
 1.4
 1.2
 5.0
 0.7
 3.1

3.4
4 CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 790 0 9.1 8.3
 3.9
 7.7
 6.0
1.3
 5.9
-0.4
 6.5
-0.1
 5.6
-0.3
 7.1
-0.2
 3.6
0.8
 6.9
0.4
 4.0
0.2
 8.2
0.3
 3.1
-0.4
 5.3
1.1
 1.1
0.4
 4.6
0.6
 0.7
 2.7
 2.7
 -0.1
 2.6
2.4
 -1.0
5 NOC2L NOC2 like nucleolar associated transcriptional repressor 26155 0 9.1 9.2
 1.1
 6.8
 1.7
 2.9
 3.7
 2.9
 4.3
 2.8
 3.6
 2.6
 4.9
 0.5
 0.4
 0.3
 2.9
 -0.3
 2.4
 2.9
 4.2
 0.9
 -0.6
6 BOP1 BOP1 ribosomal biogenesis factor 23246 0 9.0 9.2
 6.1
 6.6
 3.2
 2.9
 7.7
 1.7
 5.6
 0.8
 4.6
 1.2
 4.5
 3.0
 3.3
 1.0
 5.8
 -1.2
 3.8
 2.7
 2.5
 1.3
 -1.3
7 PFAS phosphoribosylformylglycinamidine synthase 5198 0 8.9 8.9
 2.2
 6.7
 4.2
 2.6
 5.8
 1.9
 3.5
 2.0
 4.1
 2.7
 3.8
 3.5
 2.6
 1.1
 1.9
 0.7
 1.4
 -0.4
 1.2
 4.7
 0.3
8 NOL6 nucleolar protein 6 65083 0 8.7 7.8
 3.8
 7.5
 2.4
 2.4
 5.4
 2.8
 4.1
 2.7
 4.2
 1.9
 3.0
 -0.1
 3.1
 2.3
 4.2
 0.6
 3.3
 3.4
 4.1
 2.8
 -0.4
9 TBL3 transducin beta like 3 10607 0 8.4 7.0
 3.3
 7.9
 3.1
 3.2
 5.6
 2.8
 5.4
 2.3
 4.7
 3.2
 5.7
 0.2
 1.8
 1.6
 4.4
 0.2
 4.2
 3.0
 6.0
 0.5
 2.2
10 BYSL bystin like 705 0 8.3 8.4
 3.1
 6.3
 3.9
 0.6
 5.0
 1.3
 2.8
 -1.1
 5.5
 2.7
 5.7
 1.7
 2.1
 -0.1
 3.4
 -0.1
 2.7
 2.4
 0.7
 -0.8
 -0.5
11 XPO5 exportin 5 57510 0 8.1 7.6
 4.4
 6.6
 3.9
 2.4
 3.6
 2.1
 6.7
 2.6
 4.2
 3.6
 4.9
 1.2
 1.4
 2.0
 3.2
 0.5
 5.3

0.9
12 GCN1 GCN1 activator of EIF2AK4 10985 0 8.0 6.8
 3.2
 7.3
 4.2
 4.9
 4.3
 4.8
 3.2
 3.4
 3.9
 3.9
 4.7
 1.0
 0.5
 1.4
 5.6
 0.0
 0.4
 4.3
 1.5
 6.5
 1.0
13 RRP12 ribosomal RNA processing 12 homolog 23223 0 7.9 7.9
 2.1
 5.9
 1.5
 1.0
 5.2
 1.5
 5.7
 1.0
 6.0
 1.7
 5.3
 3.3
 2.0
 0.9
 5.8
 -0.0
 3.9
 3.0
 3.8
 2.6
 -0.6
14 SRM spermidine synthase 6723 0 7.5 8.3
 3.1
 5.0
 1.1
 -0.1
 3.2
 -0.1
 4.6
 1.9
 4.7
 1.1
 7.7
 -0.2
 0.5
 1.3
 3.7
 1.2
 0.7
 1.4
 0.1
 2.9
0.2
 1.2
15 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 471 0 7.0 7.2
 2.3
 5.2
 1.1
 1.8
 3.8
 2.1
 3.7
 1.5
 3.2
 1.0
 3.0
 -0.2
 2.7
 1.6
 3.1
 0.5
 1.8
 -0.7
 -0.2
 0.9
-0.0
16 EIF3B eukaryotic translation initiation factor 3 subunit B 8662 0 7.0 7.6
 2.1
 4.7
 0.9
 1.3
 6.4
 0.9
 8.2
 -0.5
 5.4
 3.4
 7.7
 0.7
 5.5
 0.1
 2.3
 -1.5
 3.1
 3.2
 1.9
 4.8
 -0.4
17 INTS1 integrator complex subunit 1 26173 0 7.0 6.3
 3.8
 6.0
 3.0
 4.1
 4.7
 6.1
 5.5
 5.2
 3.4
 4.5
 5.9
 1.7
 0.5
 1.7
 1.1
 2.1
 3.4
 1.3
 1.3

18 URB1 URB1 ribosome biogenesis homolog 9875 0 6.7 5.9
 1.7
 6.0
 3.3
 2.7
 3.1
 1.8
 3.0
 1.1
 2.7
 2.7
 4.9
 0.6
 1.0
 2.9
 4.6
 -0.0
 4.8
 1.2
 4.1
 2.1
 1.8
19 SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 6597 0 6.6 5.2
 2.5
 6.4
 2.8
-0.5
 3.1
0.9
 4.1
0.1
 1.9
0.5
 5.2
-0.6
 1.5
-1.0
 3.6
-1.1
 1.4
-0.7
 4.0
-1.1
 4.5
0.6
 4.3
-0.5
 1.0
0.3
 2.3
0.3
 0.1
 0.5
 -0.5
-1.1
 0.2
-0.2
 1.5
-0.8
20 ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit 2068 0 6.5 6.8
 2.4
 4.6
 2.6
 3.3
 3.7
 4.4
 2.2
 4.0
 3.2
 1.2
 3.2
 4.9
 5.3
 0.6
 -0.1
 2.2
 1.2
 0.2
 0.4
 0.8
 1.5
21 CLUH clustered mitochondria homolog 23277 0 6.4 5.3
 1.5
 6.0
 3.9
 2.7
 4.1
 3.9
 3.4
 5.4
 4.6
 3.8
 5.2
 1.4
 0.9
 1.8
-0.1
 1.9
0.8
 2.1
 3.4
 6.2
 6.9
 4.5
 0.6
22 ATP13A1 ATPase 13A1 57130 0 6.4 5.5
 3.6
 5.7
 4.0
 2.5
 2.3
 2.7
 5.4
 3.0
 2.5
 4.7
 3.5
 2.7
 0.9
 0.9
 4.5
 3.4
 3.5
 1.6
 2.8
 1.8
 -0.1
23 SKIV2L Ski2 like RNA helicase 6499 0 6.3 8.8
 3.5
 2.3
 4.5
0.6
 3.1
0.3
 2.0
1.1
 4.2
-0.0
 5.4
0.7
 3.1
-0.4
 3.8
1.0
 4.2
0.7
 4.4
0.7
 6.7
-0.2
 5.7
1.3
 3.6
2.8
 7.0
4.8
 1.6
1.4
 3.1
3.1
 3.3
2.5
 5.3
5.1
 3.1
0.7
24 DAZAP1 DAZ associated protein 1 26528 0 6.3 5.6
 1.4
 5.5
 1.3
 0.5
 4.1
 2.0
 3.9
 2.9
 3.5
 2.5
 4.0
 1.4
 0.6
 -0.7
 0.1
 -1.5
 1.7



25 ELAC2 elaC ribonuclease Z 2 60528 0 6.3 5.5
 2.0
 5.5
 2.8
 3.8
 3.1
 4.7
 3.6
 3.0
 4.2
 3.0
 5.0
 0.7
 1.4
 3.0
 3.7
 1.4
 6.2
 5.2
 2.0
 1.0
 2.7
26 APEH acylaminoacyl-peptide hydrolase 327 0 6.3 5.4
 2.6
 5.6
 2.4
 2.0
 1.6
 2.1
 1.6
 2.6
 0.7
 2.4
 2.0
 5.0
4.1
 2.9
0.7
 4.0
0.1
 2.3
1.4

2.4
2.2
 4.6
0.3

27 PRRC2A proline rich coiled-coil 2A 7916 0 6.2 6.3
 3.9
 4.6
 4.0
 0.9
 3.1
 2.0
 2.7
 3.0
 2.4
 4.9
 5.0



-0.9
 1.8



28 ARMC6 armadillo repeat containing 6 93436 0 6.2 5.2
 1.5
 5.6
 3.0
 1.9
 3.1
 1.1
 1.6
 -1.3
 3.1
 2.6
 3.5
 -0.8
 -2.1
 1.2
 1.7
 0.7
 1.1



29 PDCD11 programmed cell death 11 22984 0 6.2 6.6
 2.9
 4.2
 2.8
 2.1
 4.9
 2.4
 3.6
 0.7
 2.4
 3.0
 4.6
 1.2
 1.5
 1.1
 5.3
 0.5
 3.2
 4.4
 6.8
 3.6
 1.8
30 SCFD2 sec1 family domain containing 2 152579 0 6.2 6.7
 2.0
 4.2
 1.0
 1.2
 1.4
 3.2
 1.3
 1.5
 0.6
 1.3
 2.5
 -0.2
 0.9
 1.7
 2.7





31 SYMPK symplekin 8189 0 6.2 5.5
 1.1
 5.3
 3.5
 2.6
 3.8
 5.7
 3.8
 2.0
 5.4
 3.1
 5.4
 7.0
 5.2
 1.1
 3.5
 1.5
 2.6
 1.5
 4.1
 -0.4
 -1.1
32 HNRNPL heterogeneous nuclear ribonucleoprotein L 3191 0 6.1 6.2
 0.7
 4.6
 0.5
-0.8
 1.1
0.9
 2.3
-0.4
 2.5
-0.6
 1.9
0.1
 2.2
0.0
 0.3
0.1
 0.0
-0.8
 1.4
-1.2
 5.5
-2.4
 2.9
0.8
 0.8
 0.7
 0.2
 -0.1
 1.7
 0.9

33 EIF4G1 eukaryotic translation initiation factor 4 gamma 1 1981 0 6.1 5.7
 2.7
 5.1
 1.6
 0.9
-1.4
 4.7
1.0
 1.9
 3.8
 0.7
0.6
 4.9
1.9
 2.7
-1.4
 5.5
-0.2
 2.2
0.1
 2.3
1.1
 1.1
0.5
 6.8
1.9
 3.7
-0.2
 3.7
-0.5
 3.9
 1.3
 5.7
34 POLR1A RNA polymerase I subunit A 25885 0 6.1 5.4
 2.8
 5.3
 2.6
 3.6
 5.0
 1.6
 3.6
 3.4
 5.0
 3.4
 5.9
 2.4
 2.5
 2.6
 4.0
 1.4
 4.5
 2.5
 2.8
 4.7
 -0.4
35 SSRP1 structure specific recognition protein 1 6749 0 6.1 7.9
 2.0
 2.8
 3.2
 2.1
 3.5
 2.0
 4.3
 0.9
 3.2
 0.3
 4.7
 1.1
 1.3
 1.2
0.4
 3.3
0.2
 1.0
 2.4
 0.6
-1.4
 2.6
1.6
 0.2
 -0.2
36 EFTUD2 elongation factor Tu GTP binding domain containing 2 9343 1 6.1 6.0
 2.1
 4.7
 2.2
 2.0
 2.1
 1.6
 6.2
 1.7
 3.7
 2.6
 2.6
 2.5
 3.4
 0.4
 4.4
 0.7
 2.6
 3.3
 1.0

37 NCLN nicalin 56926 0 6.0 4.8
 1.9
 5.8
 2.6
 2.9
 5.1
 2.7
 6.3
 3.1
 4.0
 1.2
 2.9
 -1.7
 -0.5
 1.7
1.3
 4.7
0.5
 1.6
 2.4
 2.7
 1.8

38 AHCY adenosylhomocysteinase 191 0 6.0 5.7
 2.4
 4.8
 1.8
 0.4
 3.8
 0.2
-0.6
 2.9
0.6
 0.3
 0.8
 1.2
 1.2
 -0.8
 2.3
 -1.1
 1.0
 -0.2
 2.6
 3.5
 0.7
 3.2
 -0.2
39 GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 2618 0 6.0 5.6
 2.6
 4.9
 1.7
 2.5
 4.1
 3.6
 3.0
 0.4
 3.4
 2.6
 3.7
 -1.0
 1.1
 0.9
 3.8
 -0.0
 0.8
 0.3
 0.1
 2.8
40 VARS2 valyl-tRNA synthetase 2, mitochondrial 57176 10 6.0 6.4
 2.4
 4.1
 6.0
 3.5
 3.5
 3.7
 3.7
 2.2
 2.2
 5.0
 5.0
 4.1
 4.1
 2.9
 2.9
 1.4
 1.4
 2.9
 2.9

41 TUFM Tu translation elongation factor, mitochondrial 7284 0 6.0 5.1
 1.8
 5.4
 2.3
 3.3
 2.8
 4.2
 2.1
 2.6
 2.3
 2.4
 4.5

1.7
 2.5
 2.8
1.9
 4.1
1.0
 4.3
1.1
 5.7
5.4
 0.1
 -0.5
42 RPAP1 RNA polymerase II associated protein 1 26015 0 6.0 5.7
 1.9
 4.7
 4.3
 4.0
 3.7
 4.9
 3.9
 3.9
 2.9
 3.0
 2.2
 0.9
 0.0
 4.6
 3.9
 1.4
 1.8

-0.3
43 TRAP1 TNF receptor associated protein 1 10131 0 5.9 5.6
 2.4
 4.8
 2.6
 2.7
 4.1
 3.4
 2.5
 2.7
 2.6
 2.2
 3.0
 -0.2
 1.6
 3.4
 2.2
 5.8
 2.9
 3.2
 6.6

44 PRMT5 protein arginine methyltransferase 5 10419 1 5.9 6.5
 1.7
 3.9
 1.3
 1.0
 5.2
 0.3
 3.4
 1.1
 4.4
 3.1
 4.3
 5.9
 4.2
 1.5
 3.2
 -0.6
 0.8
 3.1
 2.9
 0.5
 -0.4
45 FARSB phenylalanyl-tRNA synthetase subunit beta 10056 0 5.9 5.7
 1.1
 4.7
 -0.4
 1.6
 4.8
 0.6
 3.3
 -0.3
 3.7

0.9
 0.9
 0.4
 6.0
 2.0
 5.9
 5.6
 3.0
 3.5
 -0.6
46 FARSA phenylalanyl-tRNA synthetase subunit alpha 2193 3 5.9 5.5
 2.1
 4.9
 1.9
 0.6
 4.4
 1.0
 3.6
 1.5
 1.9
 2.1
 4.5
 2.9
 3.3
 0.5
 4.7
 1.2
 6.0
 5.3
 2.5
 3.0
 0.7
47 TCOF1 treacle ribosome biogenesis factor 1 6949 0 5.8 6.6
 1.3
 3.6
 2.3
 3.2
 2.8
 2.4
 5.6
 1.2
 5.2
 3.3
 2.7
 0.8
 0.1







48 AARS2 alanyl-tRNA synthetase 2, mitochondrial 57505 2 5.8 6.3
 1.8
 3.9
 6.4
1.5
 2.5
1.4
 4.8
1.2
 5.5
0.3
 5.1
3.2
 5.9
-1.1
 5.8
3.5
 2.4
0.3
 3.3
2.0
 0.9
0.3
 2.9
1.5
 6.0
0.5
 5.8
1.9
 0.8
 10.4
 7.0
1.6
 9.0
2.7
 7.9
49 GTF2H4 general transcription factor IIH subunit 4 2968 0 5.8 5.9
 1.9
 4.2
 12.1
 4.0
 1.9
 5.4
 3.6
 2.7
 0.6

3.2
 3.5
 3.8
 0.7
 1.4
 0.5
 2.3
 2.7
 -1.0
 0.8
50 PPRC1 PPARG related coactivator 1 23082 0 5.7 5.9
 2.0
 4.2
 1.1
 2.3
 2.0
 1.2
 3.9
 0.7
 4.7
 2.6
 3.7
 3.0
 3.0
 1.2
 1.2





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