Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4   GBX2   gastrulation brain homeobox 2 
 hsa-r.6   GBX2   gastrulation brain homeobox 2 
 hsa-m.7   GBX2   gastrulation brain homeobox 2 
 hsa-m2.4   GBX2   gastrulation brain homeobox 2 
 mmu-u.4   Gbx2   gastrulation brain homeobox 2 
 gga-u.3   GBX1   gastrulation brain homeobox 1 
 dre-u.3   gbx1   gastrulation brain homeobox 1 
 dre-u.3   gbx2   gastrulation brain homeobox 2 
 dme-u.3   unpg   unplugged 

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Top 50 coexpressed genes to GBX2 (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa4950   Maturity onset diabetes of the young  2 20 2.79
 hsa4550   Signaling pathways regulating pluripotency of stem cells  2 143 -
 hsa5224   Breast cancer  2 147 -
 hsa5165   Human papillomavirus infection  2 331 -
 hsa5200   Pathways in cancer  2 531 -

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hsa:GBX2 (gastrulation brain homeobox 2) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-u.4
for
GBX2
hsa-r.6
for
GBX2
hsa-m.7
for
GBX2
hsa-m2.4
for
GBX2
mmu-u.4
for
Gbx2
gga-u.3
for
GBX1
dre-u.3
for
gbx1
dre-u.3
for
gbx2
dme-u.3
for
unpg
1 FOXL2 forkhead box L2 668 0 8.1 5.0
 0.5
 9.3
 3.1
1.3
 2.2
1.9
 6.5
5.3
 3.3
3.3
 2.8
2.2
2 UNCX UNC homeobox 340260 0 8.0 4.4
9.6
 2.5
 0.7
 5.6
4.1
 3.1
2.5
 2.3
3 FOXC2 forkhead box C2 2303 0 7.5 3.2
 0.4
 10.0
 1.1
 2.2
 2.1
 2.2
4 NKX6-1 NK6 homeobox 1 4825 1 6.9 5.1
 4.2
 7.1
 3.5
 1.7
0.6
 4.9
4.1
 3.8
2.5
 2.0
5 SOX3 SRY-box transcription factor 3 6658 0 6.9 4.9
 2.3
 7.2
 3.5
3.5
 2.0
2.0
 5.5
3.5
 3.9
3.7
 2.2
2.0
6 ZIC5 Zic family member 5 85416 0 6.8 6.7
 3.2
 5.3
 6.6
3.9
 2.0
1.5
 3.6
3.4
 2.3
2.2
 0.3
7 VSTM2B V-set and transmembrane domain containing 2B 342865 0 6.7 2.1
9.7
 1.9
 1.6
 1.0
 0.6
8 UTF1 undifferentiated embryonic cell transcription factor 1 8433 0 6.7 2.1
 0.6
 9.6
 2.1



9 BARX1 BARX homeobox 1 56033 0 6.4 3.2
 2.1
 8.1
-0.5
 1.4
 -0.0
10 EFNA2 ephrin A2 1943 0 6.4 3.7
 3.1
 7.5
 0.6
 3.0
 1.1
-0.7
 1.1
-0.2
11 PHLDA2 pleckstrin homology like domain family A member 2 7262 0 6.1 3.0
 1.1
 7.7
 1.5
 2.2
 -0.9
 -0.4
12 FOXB1 forkhead box B1 27023 0 5.8 4.2
 2.6
 6.0
 3.1
1.3
 2.2
1.9
 6.5
5.3
 3.3
3.3
 2.8
2.2
13 TFAP2E transcription factor AP-2 epsilon 339488 0 5.8 0.8
 -0.7
 9.3
 1.2
1.1
 3.3
2.2
 1.6
1.5
 5.7
4.0
 0.2
14 DMRTA2 DMRT like family A2 63950 0 5.7 2.7
 1.4
 7.3
 1.3
 1.7
 1.3
 1.6
 1.6
15 EN2 engrailed homeobox 2 2020 0 5.6 6.3
 0.7
 3.6
 4.3
 1.5
 2.6
2.6
 4.5
2.5
 2.0
16 FAM181B family with sequence similarity 181 member B 220382 0 5.6 2.2
 2.1
 7.7
 1.8
 1.9
 3.6
 -0.0
17 RAX retina and anterior neural fold homeobox 30062 0 5.6 3.6
 1.5
 6.2
1.5
 2.4
-0.8
 5.7
2.3
 1.5
18 IER5L immediate early response 5 like 389792 0 5.5 1.3
 0.3
 8.5
 2.2
 1.2
 0.7
 0.6
19 MAFA MAF bZIP transcription factor A 389692 0 5.5 3.3
6.4
 2.7
 2.3
 -0.1
 2.2
20 CAMK2N2 calcium/calmodulin dependent protein kinase II inhibitor 2 94032 0 5.4 1.4
 0.3
 8.1
 0.3
 1.0
 1.3
 1.8
21 ZIC2 Zic family member 2 7546 0 5.4 5.9
 1.1
 3.6
 6.6
3.9
 2.0
1.5
 3.6
3.4
 2.3
2.2
 0.3
22 IRX1 iroquois homeobox 1 79192 0 5.4 2.4
 1.3
 7.0
 1.5
 2.0
 3.5
 3.4
23 LRRC26 leucine rich repeat containing 26 389816 0 5.3 1.3
8.1
 -1.7
 -0.7


24 SOX8 SRY-box transcription factor 8 30812 0 5.3 2.5
 0.9
 6.7
 1.4
0.9
 2.8
0.7
 1.5
0.4
 4.1
1.1
25 INSM1 INSM transcriptional repressor 1 3642 0 5.2 1.6
 0.4
 7.6
 3.0
 0.5
 2.0
2.0
 2.0
1.0
 1.2
0.6
26 C1QL4 complement C1q like 4 338761 0 5.2 5.4
3.7

2.3
 1.4
27 ALX4 ALX homeobox 4 60529 0 5.1 2.1
 2.0
 6.9
 0.3
 -0.2
 -1.6
 0.6
28 ZXDA zinc finger X-linked duplicated A 7789 0 5.1 -0.2
 -0.6
 9.2
 -1.2
-1.5
 0.5
 0.8
 0.4
29 SP8 Sp8 transcription factor 221833 0 5.1 4.0
 0.4
 4.9
 4.2
3.2
 0.7
 5.9
3.8
 2.5
1.6
 4.2
30 SP5 Sp5 transcription factor 389058 0 5.0 3.3
 1.3
 5.5
 1.7
 1.4
 5.4
2.5
 3.8
2.4
 3.2
1.1
31 NKX1-2 NK1 homeobox 2 390010 0 5.0 4.5
4.3
1.3
 5.8
 5.0
 3.7
0.7
32 CDK5R2 cyclin dependent kinase 5 regulatory subunit 2 8941 0 4.9 2.8
 2.4
 5.9
 2.4
 2.1


33 HOXA13 homeobox A13 3209 0 4.9 2.2
 -0.0
 6.5
0.5
 0.7
-0.7
 1.5
-0.2
34 SOX1 SRY-box transcription factor 1 6656 0 4.9 5.1
 3.9
 3.5
 3.5
3.5
 2.0
2.0
 5.5
3.5
 3.9
3.7
 2.2
2.0
35 HES5 hes family bHLH transcription factor 5 388585 0 4.9 1.9
 0.8
 6.6
 2.4
 1.3
0.5
 2.1
2.0
 1.3
0.9
36 SALL3 spalt like transcription factor 3 27164 0 4.8 3.9
 0.6
 4.6
 3.9
3.1
 2.3
0.6
 3.0
1.3
 0.7
0.7
 2.1
1.5
37 LMX1B LIM homeobox transcription factor 1 beta 4010 0 4.8 4.7
 2.6
 3.7
 0.5
 1.2
0.7
 1.5
1.1
 3.8
2.7
 2.6
2.3
38 EXOSC6 exosome component 6 118460 0 4.8 -0.1
 0.6
 8.4
1.1
 0.5
 -0.2
39 IRX5 iroquois homeobox 5 10265 0 4.6 2.7
 0.8
 5.4
 2.3
 0.7
 2.7
 4.1
40 EN1 engrailed homeobox 1 2019 0 4.6 3.9
 0.5
 4.2
 2.7
 -0.4
 4.8
 1.3
41 ZIC3 Zic family member 3 7547 0 4.6 4.6
 0.5
 3.4
 6.6
3.9
 2.0
1.5
 3.6
3.4
 2.3
2.2
 0.3
42 SLC10A4 solute carrier family 10 member 4 201780 0 4.6 3.3
 0.7
 4.8
 2.9
 1.6
 0.9
 0.6
43 FZD10 frizzled class receptor 10 11211 0 4.6 4.1
 0.5
 4.0
 3.8
 0.2
 1.9
 0.7
44 GATA5 GATA binding protein 5 140628 0 4.6 1.7
 1.6
 6.3
 1.6
1.2
 1.1
0.5
 2.6
2.2
 3.0
1.3
 1.8
1.6
45 ZNF579 zinc finger protein 579 163033 0 4.6 0.5
 0.3
 7.5
 0.0


-0.3
46 ARX aristaless related homeobox 170302 0 4.6 1.2
 1.2
 6.8
 1.5
 0.6
 3.9
1.0
 1.0
-0.1
47 PRR7 proline rich 7, synaptic 80758 0 4.5 1.5
 0.6
 6.5
 0.6
 1.4
 -0.8
 0.2
48 FAM43B family with sequence similarity 43 member B 163933 0 4.5 2.1
 2.4
 5.8
 1.0
0.7
 1.7
0.3
 0.6
0.5
 0.8
-1.1
 0.3
49 HMX3 H6 family homeobox 3 340784 0 4.5 3.2
4.7

2.9
-0.6
 4.2
3.7
 1.1
50 IRX2 iroquois homeobox 2 153572 0 4.4 3.4
 1.4
 4.3
 2.4
 2.4
 3.5
3.3
 5.3
2.9
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