| functional annotation |
| Function |
Sp8 transcription factor |
|
| GO BP |
|
GO:0009954 [list] [network] proximal/distal pattern formation
|
(32 genes)
|
IEA
|
 |
|
GO:0009953 [list] [network] dorsal/ventral pattern formation
|
(76 genes)
|
IEA
|
|
|
GO:0030326 [list] [network] embryonic limb morphogenesis
|
(117 genes)
|
IEA
|
|
|
GO:0006357 [list] [network] regulation of transcription by RNA polymerase II
|
(2601 genes)
|
IBA
|
|
|
| GO CC |
|
| GO MF |
|
GO:0000978 [list] [network] RNA polymerase II cis-regulatory region sequence-specific DNA binding
|
(1208 genes)
|
IBA
|
|
|
GO:0000981 [list] [network] DNA-binding transcription factor activity, RNA polymerase II-specific
|
(1383 genes)
|
IBA
ISA
|
|
|
GO:1990837 [list] [network] sequence-specific double-stranded DNA binding
|
(1577 genes)
|
IDA
|
|
|
GO:0046872 [list] [network] metal ion binding
|
(4237 genes)
|
IEA
|
|
|
| KEGG |
|
|
| Protein |
NP_874359.2
NP_945194.1
|
| BLAST |
NP_874359.2
NP_945194.1
|
| Orthologous |
[Ortholog page]
Sp1 (dme)
sptf-1 (cel)
Sp8 (rno)
Sp8 (mmu)
sp8a (dre)
sp8b (dre)
Sp9 (rno)
Sp9 (mmu)
sp9 (dre)
SP9 (cfa)
SP8 (cfa)
SP9 (mcc)
SP8 (mcc)
SP8 (gga)
SP9 (hsa)
SP9 (gga)
SP8 (fca)
SP9 (fca)
|
Subcellular
localization
wolf |
|
nucl 9
|
(predict for NP_874359.2)
|
|
nucl 8,
mito 1
|
(predict for NP_945194.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| hsa04550 |
Signaling pathways regulating pluripotency of stem cells |
3 |
 |
| hsa05200 |
Pathways in cancer |
2 |
 |
| hsa05224 |
Breast cancer |
2 |
 |
Genes directly connected with SP8 on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
CoexPub |
Entrez Gene ID* |
| 7.3 |
SOX21 |
SRY-box transcription factor 21 |
[detail] |
0 |
11166 |
| 6.1 |
NKX1-2 |
NK1 homeobox 2 |
[detail] |
0 |
390010 |
| 6.1 |
FOXG1 |
forkhead box G1 |
[detail] |
0 |
2290 |
| 6.0 |
OTX1 |
orthodenticle homeobox 1 |
[detail] |
0 |
5013 |
| 5.7 |
NR2E1 |
nuclear receptor subfamily 2 group E member 1 |
[detail] |
0 |
7101 |
| 5.0 |
ISL1 |
ISL LIM homeobox 1 |
[detail] |
0 |
3670 |
|
Coexpressed
gene list |
[Coexpressed gene list for SP8]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
SP8 Gene
