Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4   PTPN21   protein tyrosine phosphatase non-receptor type 21 
 hsa-r.6   PTPN21   protein tyrosine phosphatase non-receptor type 21 
 hsa-m.7   PTPN21   protein tyrosine phosphatase non-receptor type 21 
 hsa-m2.4   PTPN21   protein tyrosine phosphatase non-receptor type 21 
 hsa-u.4   PTPN14   protein tyrosine phosphatase non-receptor type 14 
 mcc-u.3   PTPN14   protein tyrosine phosphatase non-receptor type 14 
 mcc-u.3   PTPN21   protein tyrosine phosphatase non-receptor type 21 
 mmu-u.4   Ptpn21   protein tyrosine phosphatase, non-receptor type 21 
 mmu-u.4   Ptpn14   protein tyrosine phosphatase, non-receptor type 14 
 rno-u.3   Ptpn21   protein tyrosine phosphatase, non-receptor type 21 
 rno-u.3   Ptpn14   protein tyrosine phosphatase, non-receptor type 14 
 cfa-u.3   PTPN21   protein tyrosine phosphatase non-receptor type 21 
 cfa-u.3   PTPN14   protein tyrosine phosphatase non-receptor type 14 
 gga-u.3   PTPN14   protein tyrosine phosphatase non-receptor type 14 
 gga-u.3   PTPN21   protein tyrosine phosphatase non-receptor type 21 
 dre-u.3   ptpn21   protein tyrosine phosphatase non-receptor type 21 
 dme-u.3   Pez   Pez 
 spo-u.3   SPBC8D2.16c   hypothetical protein 

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Top 50 coexpressed genes to PTPN21 (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa4390   Hippo signaling pathway  6 135 5.52
 hsa4510   Focal adhesion  6 185 4.74
 hsa4392   Hippo signaling pathway - multiple species  5 21 6.38
 hsa4014   Ras signaling pathway  5 200 3.49
 hsa4151   PI3K-Akt signaling pathway  5 300 2.70

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hsa:PTPN21 (protein tyrosine phosphatase non-receptor type 21) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-u.4
for
PTPN21
hsa-r.6
for
PTPN21
hsa-m.7
for
PTPN21
hsa-m2.4
for
PTPN21
hsa-u.4
for
PTPN14
mcc-u.3
for
PTPN14
mcc-u.3
for
PTPN21
mmu-u.4
for
Ptpn21
mmu-u.4
for
Ptpn14
rno-u.3
for
Ptpn21
rno-u.3
for
Ptpn14
cfa-u.3
for
PTPN21
cfa-u.3
for
PTPN14
gga-u.3
for
PTPN14
gga-u.3
for
PTPN21
dre-u.3
for
ptpn21
dme-u.3
for
Pez
spo-u.3
for
SPBC8D2.16c
1 TEAD1 TEA domain transcription factor 1 7003 0 7.4 7.6
 2.7
 5.5
 6.2
3.6
 4.0
1.7
 3.8
2.9
 4.4
3.5
 4.8
4.0
 2.3
1.8
 3.7
3.0
 2.8
1.3
 3.5
2.6
 3.5
3.2
 2.9
2.8
 4.6
3.9
 0.4
 0.3
2 PARVA parvin alpha 55742 0 7.1 5.3
 2.7
 7.2
 4.4
0.8
 3.3
-0.1
 2.8
-0.5
 1.6
0.3
 3.2
1.3
 1.1
-0.6
 2.1
1.4
 1.6
0.4
 3.0
-0.1
 2.8
0.3
 1.5
0.8
 3.0
-0.3
 2.4
3 TJP1 tight junction protein 1 7082 0 6.8 7.1
 3.1
 4.9
 3.9
 0.8
 3.1
 2.1
 3.6
 2.1
 1.7
 2.2
 2.4
 3.5
 2.4
 2.3
1.1
 1.3
4 SAMD4A sterile alpha motif domain containing 4A 23034 0 6.2 5.7
 3.4
 5.2
 2.8
0.9
 0.2
-0.5
 0.2
-1.0
 5.1
1.9
 3.3
1.0
 3.2
-0.1
 1.2
0.8
 2.2
1.0
 3.7
0.7
 0.6
-0.8
 2.3
-1.4
 4.4
1.4
 4.7
 -0.9
5 AMOTL2 angiomotin like 2 51421 0 5.5 5.4
 2.0
 4.3
 4.8
4.4
 2.3
1.8
 2.8
1.5
 4.2
3.0
 5.3
3.8
 2.7
0.5
 3.0
2.9
 2.4
0.6
 3.6
3.2
 3.6
2.2
 2.5
2.0
 4.5
1.6
0.4
6 WTIP WT1 interacting protein 126374 0 5.2 4.2
 1.7
 4.9
 2.7
0.6
 1.5
0.5
 1.3
-0.4
 2.8
2.0
 2.1
1.1
 2.4
1.3
 2.3
1.7
 2.3
1.6
 3.1
1.6
 3.3
0.6
 0.5
0.3
 3.6
3.6
 0.9
7 FERMT2 FERM domain containing kindlin 2 10979 0 5.1 4.8
 2.4
 4.2
 2.4
 1.1
 3.7
 2.3
 1.7
 1.9
 1.3
 1.6
 2.7
 1.1
 2.1
 4.6
 3.0
1.4
8 CAP2 cyclase associated actin cytoskeleton regulatory protein 2 10486 0 5.1 4.4
 2.0
 4.6
 3.1
0.7
 0.8
-1.1
 0.4
-0.2
 0.5
-0.6
 0.7
-0.7
 0.0
-1.4
 0.4
-2.4
 1.0
0.0
 0.5
-1.0
 -0.4
-1.6
 2.1
-0.9
 0.1
-1.0
 1.4
 -0.6
9 SH3D19 SH3 domain containing 19 152503 0 5.1 4.4
 3.0
 4.6
 2.8
 1.4
 1.2
 3.0
 2.0
 2.4
 0.3
 2.7
 1.2
 1.4
 1.7
 0.7
 4.6
10 SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2 6655 0 5.0 3.8
 1.7
 5.0
 0.6
0.5
 0.1
-0.3
 0.7
-0.8
 3.0
0.4
 0.1
-0.1
 1.8
0.9
 1.3
0.1
 1.5
0.6
 0.7
0.1
 1.1
1.0
 -0.7
-0.9
 0.8
0.5
 2.3
11 PTPN14 protein tyrosine phosphatase non-receptor type 14 5784 0 5.0 4.4
 2.0
 4.4
 5.0
 1.5
 1.5
 3.6
 3.6
 3.0
 3.0
 2.1
 2.1
 3.0
 3.0


12 PPP2R3A protein phosphatase 2 regulatory subunit B''alpha 5523 0 4.9 4.6
 2.3
 4.1
 3.1
-0.1
 0.9
 1.8
 1.7
-0.0
 -0.9
-1.1
 0.5
-0.6
 0.6
-0.8
 1.1
0.2
 0.9
0.1
 1.3
0.8
 3.0
-0.5
 0.2
-0.3
 1.1
13 SYDE1 synapse defective Rho GTPase homolog 1 85360 0 4.7 4.1
 1.9
 4.3
 3.8
2.8
 3.2
2.3
 2.4
1.5
 4.4
0.7
 4.5
1.4
 2.8
2.7
 3.4
1.7
 1.5
0.9
 1.4
1.3
 1.9
0.2
 1.3
0.9
 4.2
1.5
 -1.3
14 GNG12 G protein subunit gamma 12 55970 0 4.6 4.8
 2.0
 3.3
 3.4
1.5
 1.1
0.5
 1.6
0.5
 1.5
0.7
 0.4
0.2
 0.7
0.4
 0.4
0.4
 0.3
0.0
 2.0
0.5
 3.9
1.1
 0.8
0.6
 2.2
1.0
 -0.1
-2.2
15 RASAL2 RAS protein activator like 2 9462 0 4.6 4.5
 2.0
 3.7
 6.0
1.8
 1.3
0.7
 1.3
0.1
 3.2
3.2
 2.2
1.8
 1.7
1.3
 1.4
1.0
 2.3
1.8
 4.2
2.2
 1.1
-0.2
 1.1
0.1
 2.4
1.5
 1.7
 -0.2
-0.8
16 YAP1 Yes1 associated transcriptional regulator 10413 3 4.6 4.8
 2.3
 3.3
 6.4
4.6
 2.2
1.2
 2.4
1.1
 3.4
3.3
 5.4
3.7
 5.0
2.0
 3.9
1.9
 2.3
0.4
 4.0
0.4
 3.8
2.4
 2.1
0.3
 3.6
3.5
 1.5
17 POMT2 protein O-mannosyltransferase 2 29954 0 4.5 3.4
 1.6
 4.5
 0.0
 0.0
 2.2
 1.5
 0.9
 0.0
 0.4
 0.5
 -0.1
 1.8
 -0.5
 0.5
 -0.4
 0.1
18 WWC2 WW and C2 domain containing 2 80014 0 4.5 4.1
 1.8
 3.8
 4.3
1.8
 2.1
1.1
 1.7
-0.5
 4.9
2.9
 3.9
1.7
 3.4
0.7
 2.1
0.9
 3.6
-0.2
 3.7
2.5
 3.5
0.4
 1.8
1.7
 8.8
 1.7
19 THSD4 thrombospondin type 1 domain containing 4 79875 0 4.5 4.6
 1.4
 3.3
 2.1
 1.2
 0.3
 1.0
 2.7
 0.8
 1.1

3.1
 1.3
 -0.1
-1.3
 0.9
20 BEND7 BEN domain containing 7 222389 0 4.4 3.5
 1.8
 4.3
 1.5
 -0.3
 1.9
 2.1
 -1.1
 1.3
 0.1
 0.2
 2.1
 -1.2
 -0.4


21 EML1 EMAP like 1 2009 0 4.4 4.4
 1.8
 3.4
 1.1
0.1
 1.1
0.3
 1.9
0.7
 1.4
0.4
 1.0
0.4
 0.8
0.0
 1.2
-0.9
 1.8
1.5
 1.3
1.2
 1.4
1.2
 2.6
0.7
 1.3
0.8
 1.1
 -0.0
-0.1
22 EGFR epidermal growth factor receptor 1956 0 4.4 3.5
 2.4
 4.1
 5.3
1.3
 2.6
1.0
 1.9
1.8
 1.9
0.2
 3.5
1.2
 1.9
0.3
 3.9
1.9
 1.7
1.0
 3.0
2.9
 3.1
0.8
 1.3
1.1
 4.2
3.8
 0.7
23 PXDC1 PX domain containing 1 221749 0 4.3 3.7
 1.6
 3.8
 1.1
 0.4
 0.6
 1.4
 2.6
 1.1
 0.5
 1.3
 1.3
 -1.1
 0.6
 -1.0

24 PARD3B par-3 family cell polarity regulator beta 117583 0 4.3 3.9
 1.6
 3.6
 4.1
3.0
 2.1
2.0
 2.4
0.3
 3.7
3.4
 1.7
1.3
 3.8
2.2
 2.0
1.4
 2.0
1.2
 2.0
1.4
 3.7
2.0
 2.3
0.8
 3.9
2.8
 3.3
 -1.6
25 MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 9223 0 4.2 4.3
 2.6
 3.1
 5.4
 0.5
 0.3
 2.9
 1.0
 1.8
 0.6
 0.4
 1.5
 0.2
 0.3
 -1.4
-2.0
 4.6
26 PLCE1 phospholipase C epsilon 1 51196 0 4.2 3.9
 2.3
 3.5
 1.6
 0.5
 1.3
 2.0
 1.5
 2.5
 1.2
 0.6
 0.6
 2.6
 2.2
 1.0

27 MPDZ multiple PDZ domain crumbs cell polarity complex component 8777 0 4.2 4.1
 1.4
 3.3
 2.9
 1.3
0.3
 3.8
0.1
 1.7
 2.7
 2.5
 4.6
 0.9
0.5
 1.8
1.2
 2.7
2.3
 3.3
1.3
 1.2
1.1
 0.3
-0.7
 -0.3
28 DOCK1 dedicator of cytokinesis 1 1793 0 4.1 3.1
 2.0
 4.2
 4.5
2.9
 1.8
0.3
 0.9
0.8
 1.3
1.2
 1.8
0.8
 1.1
0.6
 2.0
1.4
 1.2
0.1
 2.7
1.9
 3.8
1.4
 0.7
0.5
 2.0
1.9
 1.6
1.2
29 DLG5 discs large MAGUK scaffold protein 5 9231 0 4.1 3.2
 1.2
 4.0
 3.5
 0.8
 0.4
 3.1
 2.7
 1.1
 2.3
 1.6
 -0.5
 2.9
 2.7
 3.2
2.1
 5.3
 1.0
30 TEAD3 TEA domain transcription factor 3 7005 0 4.1 3.8
 1.6
 3.3
 6.2
3.6
 4.0
1.7
 3.8
2.9
 4.4
3.5
 4.8
4.0
 2.3
1.8
 3.7
3.0
 2.8
1.3
 3.5
2.6
 3.5
3.2
 2.9
2.8
 4.6
3.9
 0.4
 0.3
31 ILK integrin linked kinase 3611 0 4.1 3.0
 1.5
 4.1
 1.7
 0.6
 0.9
 1.1
 0.4
 0.9
 -1.4
 0.8
 0.1
 -0.2
 1.4
 1.8
 1.8
32 UNC13B unc-13 homolog B 10497 0 4.1 3.5
 1.7
 3.6
 1.1
0.8
 -0.4
-1.0
 -0.5
-0.7
 2.8
0.1
 0.5
-0.3
 0.7
0.7
 1.7
0.9
 0.9
0.2
 1.1
-0.4
 1.3
0.6
 1.4
-0.2
 1.5
0.6
 -0.7
33 BCAR1 BCAR1 scaffold protein, Cas family member 9564 0 4.0 3.3
 1.2
 3.8
 1.4
 1.1
 2.1
 2.8
 1.8
 1.5
 0.5
 2.1
 1.8
 1.5
 0.4
 -0.6
 0.2
34 NUAK1 NUAK family kinase 1 9891 0 4.0 2.8
 0.7
 4.2
 4.0
0.4
 0.3
-1.1
 -0.0
-0.1
 3.6
1.9
 2.5
0.8
 0.7
0.3
 0.9
0.8
 3.1
-0.7
 1.7
1.3
 0.7
-0.3
 2.0
-0.0
 1.0
1.0
 -0.2
 0.7
35 SH3BP4 SH3 domain binding protein 4 23677 0 4.0 3.1
 1.1
 3.9
 2.9
 1.5
 4.4
 0.9
 4.6
 0.0
 3.6
 0.9
 3.4
 1.9
 2.0
 -0.4

36 LATS2 large tumor suppressor kinase 2 26524 0 4.0 4.3
 0.8
 2.7
 4.1
1.6
 2.3
0.4
 1.1
-0.2
 3.3
1.6
 2.1
-0.2
 3.8
2.9
 2.2
1.0
 2.1
0.6
 3.2
1.8
 3.4
1.7
 3.9
0.8
 2.7
2.5
 1.7
37 NR2F2 nuclear receptor subfamily 2 group F member 2 7026 0 3.9 3.5
 0.8
 3.5
 2.2
0.5
 1.9
0.6
 1.7
0.9
 1.2
0.7
 1.1
0.6
 0.6
0.6
 2.3
1.4
 0.1
-0.1
 1.6
0.5
 0.6
0.1
 1.4
0.2
 1.6
0.8
 -0.1
-0.5
38 CCN1 cellular communication network factor 1 3491 0 3.9 3.9
 2.0
 3.0
 3.7
2.3
 3.0
1.0
 1.6
1.6
 3.7
2.2
 3.4
3.3
 2.6
2.0
 2.7
1.9
 1.1
1.0
 4.1
2.5
 1.1
0.9
 2.2
1.7
 1.4
1.3
 0.1
39 OTUD7B OTU deubiquitinase 7B 56957 0 3.8 3.4
 1.9
 3.3
 2.5
 1.6
-0.7
 1.4
0.3
 5.2
-0.0
 2.5
-0.3
 3.5
-0.9
 1.1
0.2
 2.5
 1.1
 0.9
0.9
 0.6
0.5
 5.3
-0.8

40 CDC42BPB CDC42 binding protein kinase beta 9578 0 3.8 3.0
 2.2
 3.7
 4.9
1.8
 0.8
0.7
 0.9
0.5
 3.7
3.0
 2.4
2.0
 2.3
1.0
 1.7
1.6
 3.3
2.7
 3.8
1.4
 4.5
0.4
 2.2
1.3
 7.7
1.1
 1.7
41 SLC12A4 solute carrier family 12 member 4 6560 0 3.8 2.8
 1.9
 3.9
 2.8
0.4
 1.2
0.5
 0.7
0.1
 2.1
0.5
 3.6
1.2
 3.5
2.4
 2.6
1.4
 2.9
2.1
 1.6
-0.0
 1.1
0.3
 1.2
0.8
 2.9
2.1
 0.5
42 DENND2B DENN domain containing 2B 6764 0 3.7 2.9
 1.1
 3.7
 2.4
 1.2
 2.7
 2.2
 2.6
 3.2
 1.7
 0.8
 2.4
 0.4
 -0.5
 -0.6

43 PHLDB1 pleckstrin homology like domain family B member 1 23187 0 3.7 3.2
 1.0
 3.3
 2.3
 0.1
 1.4
 0.9
 2.5
 1.3
 2.3
 1.5
 2.6
 0.4
 0.6
 3.0

44 SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 57522 0 3.7 3.1
 2.3
 3.4
 2.8
2.0
 -0.1
-0.5
 1.9
-0.3
 1.5
0.6
 2.2
0.7
 0.9
0.3
 0.8
-0.1
 1.9
0.1
 2.0
1.8
 1.1
0.2
 0.6
-0.4
 3.2
2.4
0.7
-0.4
45 CEP170B centrosomal protein 170B 283638 0 3.7 3.0
 1.7
 3.5
 1.4
 1.0
 0.1
 4.9
 2.4
 2.4
 2.1
 2.1
 1.3
 2.6
 1.5
 1.7

46 CASKIN2 CASK interacting protein 2 57513 0 3.7 3.7
 1.3
 2.8
 1.4
-0.6
 0.7
-0.3
 2.6
-1.5
 2.5
-1.1
 4.0
-1.5
 1.0
-0.7
 2.9
0.2
 0.1
-0.3
 2.0
0.6
 1.6
0.4
 1.4
0.9
 2.2
1.5
 -0.2
 -2.4
47 ZNF704 zinc finger protein 704 619279 0 3.7 3.3
 1.1
 3.1
 1.3
1.0
 1.0
0.8
 1.4
0.7
 3.1
1.3
 0.7
0.6
 2.3
2.2
 2.5
0.7
 2.5
1.2
 1.6
0.5
 2.2
1.0
 1.8
1.4
 4.9
2.8

48 SH3RF1 SH3 domain containing ring finger 1 57630 0 3.7 3.1
 1.5
 3.3
 3.1
1.4
 1.2
-0.5
 0.9
-0.3
 2.2
0.3
 2.2
1.8
 0.7
 -0.2
 0.7
0.5
 2.6
1.7
 1.2
0.1
 -0.7
-0.9
 0.3
 4.6
 1.2
49 VGLL3 vestigial like family member 3 389136 0 3.7 2.8
 1.3
 3.6
 3.0
 2.2
 2.3
 2.4
 3.7
 0.8
 2.7
 2.2
 2.6
 1.9
 2.5


50 MYO1C myosin IC 4641 0 3.7 2.6
 0.9
 3.9
 3.4
1.8
 0.5
0.1
 2.1
0.3
 3.6
-0.5
 2.4
0.1
 2.1
0.1
 1.5
0.3
 0.7
0.4
 2.6
0.7
 1.5
1.3
 2.2
0.1
 1.7
0.8
 -0.4
 1.1
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