functional annotation |
Function |
histocompatibility 2, K1, K region |
|
GO BP |
GO:0002485 [list] [network] antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
|
(3 genes)
|
IDA
|
|
GO:0042590 [list] [network] antigen processing and presentation of exogenous peptide antigen via MHC class I
|
(8 genes)
|
IDA
|
|
GO:0002486 [list] [network] antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
|
(33 genes)
|
IBA
|
|
GO:0002476 [list] [network] antigen processing and presentation of endogenous peptide antigen via MHC class Ib
|
(34 genes)
|
IBA
|
|
GO:0002474 [list] [network] antigen processing and presentation of peptide antigen via MHC class I
|
(49 genes)
|
IEA
|
|
GO:0001916 [list] [network] positive regulation of T cell mediated cytotoxicity
|
(51 genes)
|
IBA
IDA
|
|
GO:0019882 [list] [network] antigen processing and presentation
|
(107 genes)
|
IEA
|
|
GO:0010977 [list] [network] negative regulation of neuron projection development
|
(162 genes)
|
IDA
IMP
|
|
GO:0048839 [list] [network] inner ear development
|
(216 genes)
|
IDA
|
|
GO:0042742 [list] [network] defense response to bacterium
|
(458 genes)
|
IDA
|
|
GO:0006955 [list] [network] immune response
|
(1640 genes)
|
IBA
|
|
GO:0002376 [list] [network] immune system process
|
(2502 genes)
|
IEA
|
|
|
GO CC |
GO:0042824 [list] [network] MHC class I peptide loading complex
|
(11 genes)
|
ISO
|
|
GO:0071556 [list] [network] integral component of lumenal side of endoplasmic reticulum membrane
|
(16 genes)
|
TAS
|
|
GO:0005797 [list] [network] Golgi medial cisterna
|
(20 genes)
|
ISO
|
|
GO:0032398 [list] [network] MHC class Ib protein complex
|
(24 genes)
|
ISO
|
|
GO:0042612 [list] [network] MHC class I protein complex
|
(26 genes)
|
ISO
|
|
GO:0030670 [list] [network] phagocytic vesicle membrane
|
(27 genes)
|
TAS
|
|
GO:0070971 [list] [network] endoplasmic reticulum exit site
|
(28 genes)
|
ISO
|
|
GO:0033106 [list] [network] cis-Golgi network membrane
|
(29 genes)
|
ISO
|
|
GO:0031901 [list] [network] early endosome membrane
|
(97 genes)
|
ISO
|
|
GO:0005765 [list] [network] lysosomal membrane
|
(172 genes)
|
ISO
|
|
GO:0000139 [list] [network] Golgi membrane
|
(268 genes)
|
ISO
|
|
GO:0005769 [list] [network] early endosome
|
(322 genes)
|
ISO
|
|
GO:0009897 [list] [network] external side of plasma membrane
|
(621 genes)
|
IBA
IDA
|
|
GO:0009986 [list] [network] cell surface
|
(1142 genes)
|
ISO
|
|
GO:0005794 [list] [network] Golgi apparatus
|
(1525 genes)
|
ISO
|
|
GO:0005783 [list] [network] endoplasmic reticulum
|
(1825 genes)
|
ISO
|
|
GO:0005615 [list] [network] extracellular space
|
(2015 genes)
|
IBA
|
|
GO:0005886 [list] [network] plasma membrane
|
(5442 genes)
|
ISO
|
|
GO:0016021 [list] [network] integral component of membrane
|
(5954 genes)
|
IEA
|
|
GO:0016020 [list] [network] membrane
|
(9571 genes)
|
IEA
|
|
|
GO MF |
GO:0062061 [list] [network] TAP complex binding
|
(5 genes)
|
ISO
|
|
GO:0042610 [list] [network] CD8 receptor binding
|
(25 genes)
|
ISO
|
|
GO:0030881 [list] [network] beta-2-microglobulin binding
|
(26 genes)
|
ISO
|
|
GO:0046979 [list] [network] TAP2 binding
|
(26 genes)
|
ISO
|
|
GO:0046978 [list] [network] TAP1 binding
|
(27 genes)
|
ISO
|
|
GO:0042608 [list] [network] T cell receptor binding
|
(33 genes)
|
ISO
|
|
GO:0046703 [list] [network] natural killer cell lectin-like receptor binding
|
(41 genes)
|
ISO
|
|
GO:0042288 [list] [network] MHC class I protein binding
|
(43 genes)
|
IPI
ISO
|
|
GO:0071889 [list] [network] 14-3-3 protein binding
|
(55 genes)
|
ISO
|
|
GO:0042605 [list] [network] peptide antigen binding
|
(67 genes)
|
IBA
IDA
ISO
|
|
GO:0051087 [list] [network] chaperone binding
|
(107 genes)
|
ISO
|
|
GO:0042803 [list] [network] protein homodimerization activity
|
(780 genes)
|
ISO
|
|
GO:0005102 [list] [network] signaling receptor binding
|
(1742 genes)
|
IBA
ISO
|
|
GO:0042802 [list] [network] identical protein binding
|
(2357 genes)
|
ISO
|
|
GO:0005515 [list] [network] protein binding
|
(9507 genes)
|
IPI
|
|
|
KEGG |
mmu04144 [list] [network] Endocytosis (272 genes) |
|
mmu04145 [list] [network] Phagosome (182 genes) |
|
mmu04218 [list] [network] Cellular senescence (184 genes) |
|
mmu04514 [list] [network] Cell adhesion molecules (174 genes) |
|
mmu04612 [list] [network] Antigen processing and presentation (90 genes) |
|
mmu04650 [list] [network] Natural killer cell mediated cytotoxicity (121 genes) |
|
mmu04940 [list] [network] Type I diabetes mellitus (70 genes) |
|
mmu05163 [list] [network] Human cytomegalovirus infection (256 genes) |
|
mmu05165 [list] [network] Human papillomavirus infection (362 genes) |
|
mmu05166 [list] [network] Human T-cell leukemia virus 1 infection (250 genes) |
|
mmu05167 [list] [network] Kaposi sarcoma-associated herpesvirus infection (224 genes) |
|
mmu05168 [list] [network] Herpes simplex virus 1 infection (459 genes) |
|
mmu05169 [list] [network] Epstein-Barr virus infection (231 genes) |
|
mmu05170 [list] [network] Human immunodeficiency virus 1 infection (240 genes) |
|
mmu05203 [list] [network] Viral carcinogenesis (229 genes) |
|
mmu05320 [list] [network] Autoimmune thyroid disease (79 genes) |
|
mmu05330 [list] [network] Allograft rejection (63 genes) |
|
mmu05332 [list] [network] Graft-versus-host disease (63 genes) |
|
mmu05416 [list] [network] Viral myocarditis (88 genes) |
|
Protein |
NP_001001892.2
NP_001334275.1
XP_006523736.1
XP_006523737.1
XP_006523739.1
XP_006523740.1
XP_006523741.1
XP_017172747.1
XP_017172748.1
XP_030105365.1
XP_030105366.1
|
BLAST |
NP_001001892.2
NP_001334275.1
XP_006523736.1
XP_006523737.1
XP_006523739.1
XP_006523740.1
XP_006523741.1
XP_017172747.1
XP_017172748.1
XP_030105365.1
XP_030105366.1
|
Orthologous |
[Ortholog page]
HLA-A (hsa)
HLA-B (hsa)
HLA-C (hsa)
HLA-E (hsa)
HLA-F (hsa)
HLA-G (hsa)
H2-Bl (mmu)
H2-D1 (mmu)
H2-L (mmu)
H2-M2 (mmu)
H2-M3 (mmu)
H2-Q1 (mmu)
H2-Q10 (mmu)
H2-Q2 (mmu)
H2-Q4 (mmu)
H2-Q7 (mmu)
H2-Q8 (mmu)
H2-T23 (mmu)
H2-T3 (mmu)
RT1-EC2 (rno)
RT1-M3-1 (rno)
RT1-N1 (rno)
RT1-N3 (rno)
RT1-A1 (rno)
RT1-A2 (rno)
RT1-Cl (rno)
RT1-M2 (rno)
LOC68395 (mmu)
Gm10499 (mmu)
H2-Q6 (mmu)
H2-Q9 (mmu)
H2-M5 (mmu)
RT1-S3 (rno)
RT1-M4 (rno)
RT1-CE12 (rno)
RT1-CE1 (rno)
RT1-CE5 (rno)
RT1-A3 (rno)
RT1-N2 (rno)
RT1-CE7 (rno)
RT1-T18 (rno)
RT1-CE14 (rno)
RT1-CE2 (rno)
RT1-CE4 (rno)
RT1-CE15 (rno)
RT1-CE13 (rno)
RT1-CE11 (rno)
RT1-CE10 (rno)
RT1-CE3 (rno)
RT1-CE16 (rno)
DLA88 (cfa)
DLA-64 (cfa)
DLA-79 (cfa)
RT1-M5 (rno)
DLA-12 (cfa)
LOC547349 (mmu)
Gm7030 (mmu)
H2-T-ps (mmu)
Gm8909 (mmu)
LOC694372 (mcc)
MAMU-A3 (mcc)
MAMU-B (mcc)
MAMU-F (mcc)
MAMU-E (mcc)
MAMU-A (mcc)
LOC714964 (mcc)
LOC715737 (mcc)
LOC719250 (mcc)
LOC719702 (mcc)
LOC720132 (mcc)
LOC720309 (mcc)
LOC720351 (mcc)
MAMU-I (mcc)
LOC721575 (mcc)
LOC722711 (mcc)
LOC723473 (mcc)
FLA-I (fca)
MAMU-B18 (mcc)
MAMU-AG (mcc)
RT1-A (rno)
LOC100424348 (mcc)
LOC100426197 (mcc)
Gm11127 (mmu)
LOC100685196 (cfa)
LOC101080285 (fca)
LOC101080790 (fca)
LOC101081297 (fca)
LOC101094232 (fca)
FLAI-K (fca)
LOC101099296 (fca)
LOC105260551 (fca)
LOC106995452 (mcc)
LOC106996081 (mcc)
LOC106996627 (mcc)
LOC106996676 (mcc)
LOC106997893 (mcc)
LOC111556177 (fca)
LOC114676051 (mcc)
LOC114677644 (mcc)
LOC119876868 (cfa)
LOC120093125 (rno)
LOC120893167 (rno)
|
Subcellular localization wolf |
plas 3,
extr 3,
extr_plas 3,
E.R. 2,
golg 2,
E.R._golg 2
|
(predict for NP_001001892.2)
|
extr 3,
plas 3,
E.R. 2,
golg 1,
pero 1,
lyso 1,
cyto_golg 1
|
(predict for NP_001334275.1)
|
extr 3,
extr_plas 3,
plas 2,
lyso 2,
golg 2,
E.R. 1,
cyto_golg 1
|
(predict for XP_006523736.1)
|
E.R. 2,
golg 2,
E.R._golg 2,
extr 2,
lyso 2
|
(predict for XP_006523737.1)
|
E.R. 2,
golg 2,
E.R._golg 2,
extr 2,
lyso 2
|
(predict for XP_006523739.1)
|
E.R. 2,
golg 2,
E.R._golg 2,
extr 2,
plas 2,
lyso 2
|
(predict for XP_006523740.1)
|
E.R. 2,
golg 2,
E.R._golg 2,
extr 2,
plas 2,
lyso 2
|
(predict for XP_006523741.1)
|
E.R. 2,
golg 2,
E.R._golg 2,
extr 2,
lyso 2
|
(predict for XP_017172747.1)
|
extr 3,
plas 3,
E.R. 2,
golg 2,
E.R._golg 2
|
(predict for XP_017172748.1)
|
plas 2,
extr_plas 2,
extr 2,
lyso 2,
golg 2,
E.R. 1,
pero 1,
cyto_golg 1
|
(predict for XP_030105365.1)
|
extr 3,
plas 3,
E.R. 2,
golg 2,
E.R._golg 2
|
(predict for XP_030105366.1)
|
|
Gene coexpression |
Network*for coexpressed genes |
KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
mmu04612 |
Antigen processing and presentation |
14 |
|
mmu05166 |
Human T-cell leukemia virus 1 infection |
14 |
|
mmu05168 |
Herpes simplex virus 1 infection |
14 |
|
mmu05169 |
Epstein-Barr virus infection |
14 |
|
mmu04145 |
Phagosome |
13 |
|
Genes directly connected with H2-K1 on the network
coex z* |
Locus |
Function* |
Coexpression detail |
CoexPub |
Entrez Gene ID* |
26.9 |
H2-D1 |
histocompatibility 2, D region locus 1 |
[detail] |
5 |
14964 |
14.4 |
H2-Q4 |
histocompatibility 2, Q region locus 4 |
[detail] |
1 |
15015 |
14.2 |
B2m |
beta-2 microglobulin |
[detail] |
28 |
12010 |
14.1 |
H2-L |
histocompatibility 2, D region locus L |
[detail] |
6 |
14980 |
14.1 |
H2-T23 |
histocompatibility 2, T region locus 23 |
[detail] |
3 |
15040 |
13.7 |
H2-Q6 |
histocompatibility 2, Q region locus 6 |
[detail] |
0 |
110557 |
11.3 |
H2-M3 |
histocompatibility 2, M region locus 3 |
[detail] |
3 |
14991 |
11.0 |
H2-Q5 |
histocompatibility 2, Q region locus 5 |
[detail] |
0 |
15016 |
10.7 |
H2-T22 |
histocompatibility 2, T region locus 22 |
[detail] |
1 |
15039 |
|
Coexpressed gene list |
[Coexpressed gene list for H2-K1]
|
Gene expression |
All samples |
[Expression pattern for all samples]
|
Tissue specificity* |
|