[][] mmu  H2-K1 Gene
functional annotation
Function   histocompatibility 2, K1, K region
GO BP
GO:0002485 [list] [network] antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent  (3 genes)  IDA  
GO:0042590 [list] [network] antigen processing and presentation of exogenous peptide antigen via MHC class I  (8 genes)  IDA  
GO:0002486 [list] [network] antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent  (33 genes)  IBA  
GO:0002476 [list] [network] antigen processing and presentation of endogenous peptide antigen via MHC class Ib  (34 genes)  IBA  
GO:0002474 [list] [network] antigen processing and presentation of peptide antigen via MHC class I  (49 genes)  IEA  
GO:0001916 [list] [network] positive regulation of T cell mediated cytotoxicity  (51 genes)  IBA IDA  
GO:0019882 [list] [network] antigen processing and presentation  (107 genes)  IEA  
GO:0010977 [list] [network] negative regulation of neuron projection development  (162 genes)  IDA IMP  
GO:0048839 [list] [network] inner ear development  (216 genes)  IDA  
GO:0042742 [list] [network] defense response to bacterium  (458 genes)  IDA  
GO:0006955 [list] [network] immune response  (1640 genes)  IBA  
GO:0002376 [list] [network] immune system process  (2502 genes)  IEA  
GO CC
GO:0042824 [list] [network] MHC class I peptide loading complex  (11 genes)  ISO  
GO:0071556 [list] [network] integral component of lumenal side of endoplasmic reticulum membrane  (16 genes)  TAS  
GO:0005797 [list] [network] Golgi medial cisterna  (20 genes)  ISO  
GO:0032398 [list] [network] MHC class Ib protein complex  (24 genes)  ISO  
GO:0042612 [list] [network] MHC class I protein complex  (26 genes)  ISO  
GO:0030670 [list] [network] phagocytic vesicle membrane  (27 genes)  TAS  
GO:0070971 [list] [network] endoplasmic reticulum exit site  (28 genes)  ISO  
GO:0033106 [list] [network] cis-Golgi network membrane  (29 genes)  ISO  
GO:0031901 [list] [network] early endosome membrane  (97 genes)  ISO  
GO:0005765 [list] [network] lysosomal membrane  (172 genes)  ISO  
GO:0000139 [list] [network] Golgi membrane  (268 genes)  ISO  
GO:0005769 [list] [network] early endosome  (322 genes)  ISO  
GO:0009897 [list] [network] external side of plasma membrane  (621 genes)  IBA IDA  
GO:0009986 [list] [network] cell surface  (1142 genes)  ISO  
GO:0005794 [list] [network] Golgi apparatus  (1525 genes)  ISO  
GO:0005783 [list] [network] endoplasmic reticulum  (1825 genes)  ISO  
GO:0005615 [list] [network] extracellular space  (2015 genes)  IBA  
GO:0005886 [list] [network] plasma membrane  (5442 genes)  ISO  
GO:0016021 [list] [network] integral component of membrane  (5954 genes)  IEA  
GO:0016020 [list] [network] membrane  (9571 genes)  IEA  
GO MF
GO:0062061 [list] [network] TAP complex binding  (5 genes)  ISO  
GO:0042610 [list] [network] CD8 receptor binding  (25 genes)  ISO  
GO:0030881 [list] [network] beta-2-microglobulin binding  (26 genes)  ISO  
GO:0046979 [list] [network] TAP2 binding  (26 genes)  ISO  
GO:0046978 [list] [network] TAP1 binding  (27 genes)  ISO  
GO:0042608 [list] [network] T cell receptor binding  (33 genes)  ISO  
GO:0046703 [list] [network] natural killer cell lectin-like receptor binding  (41 genes)  ISO  
GO:0042288 [list] [network] MHC class I protein binding  (43 genes)  IPI ISO  
GO:0071889 [list] [network] 14-3-3 protein binding  (55 genes)  ISO  
GO:0042605 [list] [network] peptide antigen binding  (67 genes)  IBA IDA ISO  
GO:0051087 [list] [network] chaperone binding  (107 genes)  ISO  
GO:0042803 [list] [network] protein homodimerization activity  (780 genes)  ISO  
GO:0005102 [list] [network] signaling receptor binding  (1742 genes)  IBA ISO  
GO:0042802 [list] [network] identical protein binding  (2357 genes)  ISO  
GO:0005515 [list] [network] protein binding  (9507 genes)  IPI  
KEGG mmu04144 [list] [network] Endocytosis (272 genes)
mmu04145 [list] [network] Phagosome (182 genes)
mmu04218 [list] [network] Cellular senescence (184 genes)
mmu04514 [list] [network] Cell adhesion molecules (174 genes)
mmu04612 [list] [network] Antigen processing and presentation (90 genes)
mmu04650 [list] [network] Natural killer cell mediated cytotoxicity (121 genes)
mmu04940 [list] [network] Type I diabetes mellitus (70 genes)
mmu05163 [list] [network] Human cytomegalovirus infection (256 genes)
mmu05165 [list] [network] Human papillomavirus infection (362 genes)
mmu05166 [list] [network] Human T-cell leukemia virus 1 infection (250 genes)
mmu05167 [list] [network] Kaposi sarcoma-associated herpesvirus infection (224 genes)
mmu05168 [list] [network] Herpes simplex virus 1 infection (459 genes)
mmu05169 [list] [network] Epstein-Barr virus infection (231 genes)
mmu05170 [list] [network] Human immunodeficiency virus 1 infection (240 genes)
mmu05203 [list] [network] Viral carcinogenesis (229 genes)
mmu05320 [list] [network] Autoimmune thyroid disease (79 genes)
mmu05330 [list] [network] Allograft rejection (63 genes)
mmu05332 [list] [network] Graft-versus-host disease (63 genes)
mmu05416 [list] [network] Viral myocarditis (88 genes)
Protein NP_001001892.2  NP_001334275.1  XP_006523736.1  XP_006523737.1  XP_006523739.1  XP_006523740.1  XP_006523741.1  XP_017172747.1  XP_017172748.1  XP_030105365.1  XP_030105366.1 
BLAST NP_001001892.2  NP_001334275.1  XP_006523736.1  XP_006523737.1  XP_006523739.1  XP_006523740.1  XP_006523741.1  XP_017172747.1  XP_017172748.1  XP_030105365.1  XP_030105366.1 
Orthologous [Ortholog page] HLA-A (hsa)HLA-B (hsa)HLA-C (hsa)HLA-E (hsa)HLA-F (hsa)HLA-G (hsa)H2-Bl (mmu)H2-D1 (mmu)H2-L (mmu)H2-M2 (mmu)H2-M3 (mmu)H2-Q1 (mmu)H2-Q10 (mmu)H2-Q2 (mmu)H2-Q4 (mmu)H2-Q7 (mmu)H2-Q8 (mmu)H2-T23 (mmu)H2-T3 (mmu)RT1-EC2 (rno)RT1-M3-1 (rno)RT1-N1 (rno)RT1-N3 (rno)RT1-A1 (rno)RT1-A2 (rno)RT1-Cl (rno)RT1-M2 (rno)LOC68395 (mmu)Gm10499 (mmu)H2-Q6 (mmu)H2-Q9 (mmu)H2-M5 (mmu)RT1-S3 (rno)RT1-M4 (rno)RT1-CE12 (rno)RT1-CE1 (rno)RT1-CE5 (rno)RT1-A3 (rno)RT1-N2 (rno)RT1-CE7 (rno)RT1-T18 (rno)RT1-CE14 (rno)RT1-CE2 (rno)RT1-CE4 (rno)RT1-CE15 (rno)RT1-CE13 (rno)RT1-CE11 (rno)RT1-CE10 (rno)RT1-CE3 (rno)RT1-CE16 (rno)DLA88 (cfa)DLA-64 (cfa)DLA-79 (cfa)RT1-M5 (rno)DLA-12 (cfa)LOC547349 (mmu)Gm7030 (mmu)H2-T-ps (mmu)Gm8909 (mmu)LOC694372 (mcc)MAMU-A3 (mcc)MAMU-B (mcc)MAMU-F (mcc)MAMU-E (mcc)MAMU-A (mcc)LOC714964 (mcc)LOC715737 (mcc)LOC719250 (mcc)LOC719702 (mcc)LOC720132 (mcc)LOC720309 (mcc)LOC720351 (mcc)MAMU-I (mcc)LOC721575 (mcc)LOC722711 (mcc)LOC723473 (mcc)FLA-I (fca)MAMU-B18 (mcc)MAMU-AG (mcc)RT1-A (rno)LOC100424348 (mcc)LOC100426197 (mcc)Gm11127 (mmu)LOC100685196 (cfa)LOC101080285 (fca)LOC101080790 (fca)LOC101081297 (fca)LOC101094232 (fca)FLAI-K (fca)LOC101099296 (fca)LOC105260551 (fca)LOC106995452 (mcc)LOC106996081 (mcc)LOC106996627 (mcc)LOC106996676 (mcc)LOC106997893 (mcc)LOC111556177 (fca)LOC114676051 (mcc)LOC114677644 (mcc)LOC119876868 (cfa)LOC120093125 (rno)LOC120893167 (rno)
Subcellular
localization
wolf
plas 3,  extr 3,  extr_plas 3,  E.R. 2,  golg 2,  E.R._golg 2  (predict for NP_001001892.2)
extr 3,  plas 3,  E.R. 2,  golg 1,  pero 1,  lyso 1,  cyto_golg 1  (predict for NP_001334275.1)
extr 3,  extr_plas 3,  plas 2,  lyso 2,  golg 2,  E.R. 1,  cyto_golg 1  (predict for XP_006523736.1)
E.R. 2,  golg 2,  E.R._golg 2,  extr 2,  lyso 2  (predict for XP_006523737.1)
E.R. 2,  golg 2,  E.R._golg 2,  extr 2,  lyso 2  (predict for XP_006523739.1)
E.R. 2,  golg 2,  E.R._golg 2,  extr 2,  plas 2,  lyso 2  (predict for XP_006523740.1)
E.R. 2,  golg 2,  E.R._golg 2,  extr 2,  plas 2,  lyso 2  (predict for XP_006523741.1)
E.R. 2,  golg 2,  E.R._golg 2,  extr 2,  lyso 2  (predict for XP_017172747.1)
extr 3,  plas 3,  E.R. 2,  golg 2,  E.R._golg 2  (predict for XP_017172748.1)
plas 2,  extr_plas 2,  extr 2,  lyso 2,  golg 2,  E.R. 1,  pero 1,  cyto_golg 1  (predict for XP_030105365.1)
extr 3,  plas 3,  E.R. 2,  golg 2,  E.R._golg 2  (predict for XP_030105366.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04612 Antigen processing and presentation 14
mmu05166 Human T-cell leukemia virus 1 infection 14
mmu05168 Herpes simplex virus 1 infection 14
mmu05169 Epstein-Barr virus infection 14
mmu04145 Phagosome 13
Genes directly connected with H2-K1 on the network
coex z* Locus Function* Coexpression
detail
CoexPub Entrez Gene ID*
26.9 H2-D1 histocompatibility 2, D region locus 1 [detail] 5 14964
14.4 H2-Q4 histocompatibility 2, Q region locus 4 [detail] 1 15015
14.2 B2m beta-2 microglobulin [detail] 28 12010
14.1 H2-L histocompatibility 2, D region locus L [detail] 6 14980
14.1 H2-T23 histocompatibility 2, T region locus 23 [detail] 3 15040
13.7 H2-Q6 histocompatibility 2, Q region locus 6 [detail] 0 110557
11.3 H2-M3 histocompatibility 2, M region locus 3 [detail] 3 14991
11.0 H2-Q5 histocompatibility 2, Q region locus 5 [detail] 0 15016
10.7 H2-T22 histocompatibility 2, T region locus 22 [detail] 1 15039
Coexpressed
gene list
[Coexpressed gene list for H2-K1]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 14972    
Refseq ID (protein) NP_001001892.2 
NP_001334275.1 
XP_006523736.1 
XP_006523737.1 
XP_006523739.1 
XP_006523740.1 
XP_006523741.1 
XP_017172747.1 
XP_017172748.1 
XP_030105365.1 
XP_030105366.1 


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