[←][→] hsa  RUNX1T1 Gene
functional annotation
Function   RUNX1 partner transcriptional co-repressor 1  
GO BP
GO:0045599 [list] [network] negative regulation of fat cell differentiation  (55 genes)  ISS  
GO:0006351 [list] [network] transcription, DNA-templated  (521 genes)  IEA  
GO:0045892 [list] [network] negative regulation of transcription, DNA-templated  (1341 genes)  IBA IDA  
GO CC
GO:0016363 [list] [network] nuclear matrix  (110 genes)  IDA  
GO:0005654 [list] [network] nucleoplasm  (4086 genes)  IDA  
GO:0005634 [list] [network] nucleus  (8115 genes)  IBA  
GO MF
GO:0003714 [list] [network] transcription corepressor activity  (186 genes)  IBA IDA TAS  
GO:0140297 [list] [network] DNA-binding transcription factor binding  (372 genes)  IPI  
GO:0003677 [list] [network] DNA binding  (2502 genes)  IEA  
GO:0046872 [list] [network] metal ion binding  (4237 genes)  IEA  
GO:0005515 [list] [network] protein binding  (13898 genes)  IPI  
KEGG hsa05200 [list] [network] Pathways in cancer (531 genes)
hsa05202 [list] [network] Transcriptional misregulation in cancer (192 genes)
hsa05221 [list] [network] Acute myeloid leukemia (67 genes)
Protein NP_001185554.1  NP_001185555.1  NP_001185556.1  NP_001185557.1  NP_001185558.1  NP_001185559.1  NP_001185560.1  NP_001185561.1  NP_001185562.1  NP_001185563.1  NP_001185608.1  NP_004340.1  NP_783552.1  NP_783553.1  NP_783554.1  XP_006716739.1  XP_011515653.1  XP_011515654.1  XP_011515655.1  XP_016869419.1  XP_016869421.1  XP_016869422.1  XP_016869423.1  XP_016869424.1  XP_016869425.1  XP_016869426.1  XP_016869427.1  XP_016869428.1  XP_016869429.1  XP_016869430.1  XP_024303085.1  XP_024303086.1 
BLAST NP_001185554.1  NP_001185555.1  NP_001185556.1  NP_001185557.1  NP_001185558.1  NP_001185559.1  NP_001185560.1  NP_001185561.1  NP_001185562.1  NP_001185563.1  NP_001185608.1  NP_004340.1  NP_783552.1  NP_783553.1  NP_783554.1  XP_006716739.1  XP_011515653.1  XP_011515654.1  XP_011515655.1  XP_016869419.1  XP_016869421.1  XP_016869422.1  XP_016869423.1  XP_016869424.1  XP_016869425.1  XP_016869426.1  XP_016869427.1  XP_016869428.1  XP_016869429.1  XP_016869430.1  XP_024303085.1  XP_024303086.1 
Orthologous [Ortholog page] CBFA2T3 (hsa)  CBFA2T2 (hsa)  Runx1t1 (mmu)  Cbfa2t2 (mmu)  Cbfa2t3 (mmu)  nvy (dme)  Cbfa2t2 (rno)  Cbfa2t3 (rno)  Runx1t1 (rno)  RUNX1T1 (gga)  CBFA2T3 (gga)  CBFA2T2 (gga)  CBFA2T2 (cfa)  RUNX1T1 (cfa)  CBFA2T3 (cfa)  cbfa2t3 (dre)  RUNX1T1 (mcc)  CBFA2T3 (mcc)  CBFA2T2 (mcc)  cbfa2t2 (dre)  runx1t1 (dre)  RUNX1T1 (fca)  CBFA2T2 (fca)  CBFA2T3 (fca) 
Subcellular
localization
wolf
nucl 6,  cyto 3,  golg 1  (predict for NP_001185554.1)
mito 8,  nucl 2,  cyto 0,  cyto_pero 0  (predict for NP_001185555.1)
mito 8,  nucl 2,  cyto 0,  cyto_pero 0  (predict for NP_001185556.1)
mito 8,  nucl 2,  cyto 0,  cyto_pero 0  (predict for NP_001185557.1)
mito 8,  nucl 2,  cyto 0,  cyto_pero 0  (predict for NP_001185558.1)
mito 8,  nucl 2,  cyto 0,  cyto_pero 0  (predict for NP_001185559.1)
mito 8,  nucl 2,  cyto 0,  cyto_pero 0  (predict for NP_001185560.1)
nucl 6,  cyto 3,  golg 1  (predict for NP_001185561.1)
nucl 6,  cyto_nucl 5,  cyto 3,  golg 1  (predict for NP_001185562.1)
nucl 6,  cyto_nucl 5,  cyto 3  (predict for NP_001185563.1)
nucl 6,  cyto_nucl 5,  cyto 3  (predict for NP_001185608.1)
nucl 6,  cyto 3,  golg 1  (predict for NP_004340.1)
mito 8,  nucl 2,  cyto 0,  cyto_pero 0  (predict for NP_783552.1)
nucl 7,  cyto 3  (predict for NP_783553.1)
nucl 7,  cyto 3  (predict for NP_783554.1)
nucl 7,  cyto 3  (predict for XP_006716739.1)
mito 8,  nucl 2,  cyto 0,  cyto_pero 0  (predict for XP_011515653.1)
nucl 6,  cyto 3,  golg 1  (predict for XP_011515654.1)
nucl 7,  cyto 3  (predict for XP_011515655.1)
nucl 5,  cyto 4  (predict for XP_016869419.1)
nucl 6,  cyto 3,  golg 1  (predict for XP_016869421.1)
nucl 6,  cyto 3,  golg 1  (predict for XP_016869422.1)
nucl 7,  cyto 3  (predict for XP_016869423.1)
nucl 7,  cyto 3  (predict for XP_016869424.1)
nucl 7,  cyto 3  (predict for XP_016869425.1)
nucl 7,  cyto 3  (predict for XP_016869426.1)
nucl 6,  cyto_nucl 5,  cyto 3  (predict for XP_016869427.1)
nucl 8,  cyto_nucl 5,  cyto 2  (predict for XP_016869428.1)
nucl 8,  cyto_nucl 5,  cyto 2  (predict for XP_016869429.1)
cyto 5,  cyto_nucl 4,  nucl 4  (predict for XP_016869430.1)
nucl 6,  cyto 3,  golg 1  (predict for XP_024303085.1)
nucl 7,  cyto 3  (predict for XP_024303086.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04015 Rap1 signaling pathway 2
hsa04151 PI3K-Akt signaling pathway 2
hsa05200 Pathways in cancer 2
hsa05206 MicroRNAs in cancer 2
Genes directly connected with RUNX1T1 on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
6.2 PDZRN3 PDZ domain containing ring finger 3 [detail] 0 23024
6.0 MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 [detail] 0 9863
5.5 PCDH18 protocadherin 18 [detail] 0 54510
5.4 PLPPR4 phospholipid phosphatase related 4 [detail] 0 9890
5.1 ZFPM2 zinc finger protein, FOG family member 2 [detail] 0 23414
5.1 SGIP1 SH3GL interacting endocytic adaptor 1 [detail] 0 84251
5.0 ZNF521 zinc finger protein 521 [detail] 0 25925
4.7 CNRIP1 cannabinoid receptor interacting protein 1 [detail] 0 25927
4.3 PLXNA4 plexin A4 [detail] 0 91584
Coexpressed
gene list		 [Coexpressed gene list for RUNX1T1]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 862      
Refseq ID (protein) NP_001185554.1 
NP_001185555.1 
NP_001185556.1 
NP_001185557.1 
NP_001185558.1 
NP_001185559.1 
NP_001185560.1 
NP_001185561.1 
NP_001185562.1 
NP_001185563.1 
NP_001185608.1 
NP_004340.1 
NP_783552.1 
NP_783553.1 
NP_783554.1 
XP_006716739.1 
XP_011515653.1 
XP_011515654.1 
XP_011515655.1 
XP_016869419.1 
XP_016869421.1 
XP_016869422.1 
XP_016869423.1 
XP_016869424.1 
XP_016869425.1 
XP_016869426.1 
XP_016869427.1 
XP_016869428.1 
XP_016869429.1 
XP_016869430.1 
XP_024303085.1 
XP_024303086.1 


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