[←][→] hsa  TFPI Gene
functional annotation
Function   tissue factor pathway inhibitor  
GO BP
GO:2000264 [list] [network] negative regulation of blood coagulation, extrinsic pathway  (4 genes)  TAS  
GO:0030195 [list] [network] negative regulation of blood coagulation  (52 genes)  IDA  
GO:0032355 [list] [network] response to estradiol  (141 genes)  IEA  
GO:0071383 [list] [network] cellular response to steroid hormone stimulus  (141 genes)  IEP  
GO:0071347 [list] [network] cellular response to interleukin-1  (178 genes)  IEA  
GO:0071222 [list] [network] cellular response to lipopolysaccharide  (191 genes)  IEA  
GO:0010951 [list] [network] negative regulation of endopeptidase activity  (255 genes)  IEA  
GO:0007596 [list] [network] blood coagulation  (308 genes)  IEA  
GO CC
GO:0005901 [list] [network] caveola  (83 genes)  IDA  
GO:0031225 [list] [network] anchored component of membrane  (170 genes)  IEA  
GO:0009986 [list] [network] cell surface  (898 genes)  HDA IDA  
GO:0005783 [list] [network] endoplasmic reticulum  (1986 genes)  IEA  
GO:0005615 [list] [network] extracellular space  (3622 genes)  IBA IDA  
GO:0005576 [list] [network] extracellular region  (4632 genes)  TAS  
GO:0005886 [list] [network] plasma membrane  (5772 genes)  TAS  
GO MF
GO:0004867 [list] [network] serine-type endopeptidase inhibitor activity  (98 genes)  IBA  
GO:0004866 [list] [network] endopeptidase inhibitor activity  (180 genes)  TAS  
KEGG hsa04610 [list] [network] Complement and coagulation cascades (85 genes)
Protein NP_001027452.1  NP_001305870.1  NP_001316168.1  NP_001316169.1  NP_001316170.1  NP_006278.1  XP_006712783.1  XP_011510011.1  XP_024308826.1  XP_024308827.1  XP_024308828.1  XP_024308829.1  XP_024308830.1 
BLAST NP_001027452.1  NP_001305870.1  NP_001316168.1  NP_001316169.1  NP_001316170.1  NP_006278.1  XP_006712783.1  XP_011510011.1  XP_024308826.1  XP_024308827.1  XP_024308828.1  XP_024308829.1  XP_024308830.1 
Orthologous [Ortholog page] TFPI2 (hsa)  Tfpi (mmu)  Tfpi2 (mmu)  Tfpi (rno)  CG15418 (dme)  F22E12.1 (cel)  mec-1 (cel)  Tfpi2 (rno)  tfpia (dre)  TFPI (cfa)  TFPI2 (gga)  TFPI (gga)  TFPI2 (cfa)  tfpi2 (dre)  TFPI (mcc)  TFPI2 (mcc)  lvs1 (spo)  T21D12.7 (cel)  TFPI2 (fca)  TFPI (fca) 
Subcellular
localization
wolf
pero 5,  extr 4  (predict for NP_001027452.1)
pero 5,  extr 4  (predict for NP_001305870.1)
extr 8,  cyto_mito 1,  mito 1  (predict for NP_001316168.1)
extr 8,  cyto_mito 1,  mito 1  (predict for NP_001316169.1)
extr 8,  cyto_mito 1,  mito 1  (predict for NP_001316170.1)
extr 8,  cyto_mito 1,  mito 1  (predict for NP_006278.1)
extr 8,  cyto_mito 1,  mito 1  (predict for XP_006712783.1)
extr 8,  cyto_mito 1,  mito 1  (predict for XP_011510011.1)
extr 8,  cyto_mito 1,  mito 1  (predict for XP_024308826.1)
pero 5,  extr 4  (predict for XP_024308827.1)
pero 5,  extr 4  (predict for XP_024308828.1)
pero 5,  extr 4  (predict for XP_024308829.1)
pero 5,  extr 4  (predict for XP_024308830.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04060 Cytokine-cytokine receptor interaction 4
hsa04062 Chemokine signaling pathway 4
hsa04151 PI3K-Akt signaling pathway 3
hsa04061 Viral protein interaction with cytokine and cytokine receptor 3
hsa04014 Ras signaling pathway 2
Genes directly connected with TFPI on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
5.7 PROS1 protein S [detail] 0 5627
5.1 GNG11 G protein subunit gamma 11 [detail] 0 2791
5.1 LEPR leptin receptor [detail] 0 3953
Coexpressed
gene list		 [Coexpressed gene list for TFPI]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 7035      
Refseq ID (protein) NP_001027452.1 
NP_001305870.1 
NP_001316168.1 
NP_001316169.1 
NP_001316170.1 
NP_006278.1 
XP_006712783.1 
XP_011510011.1 
XP_024308826.1 
XP_024308827.1 
XP_024308828.1 
XP_024308829.1 
XP_024308830.1 


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