| functional annotation |
| Function |
fibrillin 2 |
|
| GO BP |
|
GO:0035583 [list] [network] sequestering of TGFbeta in extracellular matrix
|
(4 genes)
|
ISO
|
 |
|
GO:0060346 [list] [network] bone trabecula formation
|
(9 genes)
|
ISO
|
|
|
GO:0048048 [list] [network] embryonic eye morphogenesis
|
(39 genes)
|
ISO
|
|
|
GO:0030501 [list] [network] positive regulation of bone mineralization
|
(45 genes)
|
ISO
|
|
|
GO:0045669 [list] [network] positive regulation of osteoblast differentiation
|
(73 genes)
|
ISO
|
|
|
GO:0030326 [list] [network] embryonic limb morphogenesis
|
(145 genes)
|
ISO
|
|
|
GO:0035108 [list] [network] limb morphogenesis
|
(175 genes)
|
ISO
|
|
|
GO:0043010 [list] [network] camera-type eye development
|
(398 genes)
|
ISO
|
|
|
GO:0009653 [list] [network] anatomical structure morphogenesis
|
(2302 genes)
|
IBA
|
|
|
| GO CC |
|
GO:0001527 [list] [network] microfibril
|
(12 genes)
|
ISO
|
|
|
GO:0062023 [list] [network] collagen-containing extracellular matrix
|
(244 genes)
|
IEA
|
|
|
GO:0031012 [list] [network] extracellular matrix
|
(402 genes)
|
IBA
|
|
|
GO:0005576 [list] [network] extracellular region
|
(2120 genes)
|
ISO
|
|
|
| GO MF |
|
GO:0005201 [list] [network] extracellular matrix structural constituent
|
(71 genes)
|
IBA
|
|
|
GO:0005509 [list] [network] calcium ion binding
|
(674 genes)
|
IEA
|
|
|
| KEGG |
|
|
| Protein |
NP_114014.2
XP_038953058.1
|
| BLAST |
NP_114014.2
XP_038953058.1
|
| Orthologous |
[Ortholog page]
FBN2 (hsa)
Fbn2 (mmu)
FBN3 (hsa)
FBN2 (gga)
FBN3 (gga)
FBN2 (cfa)
FBN3 (cfa)
fbn2b (dre)
FBN2 (mcc)
FBN3 (mcc)
FBN2 (fca)
FBN3 (fca)
|
Subcellular
localization
wolf |
|
extr 6,
mito 2,
cyto_mito 1,
E.R. 1
|
(predict for NP_114014.2)
|
|
cyto_nucl 4,
cyto 4,
nucl 3,
extr 1,
mito 1,
pero 1,
mito_pero 1
|
(predict for XP_038953058.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| rno04151 |
PI3K-Akt signaling pathway |
7 |
 |
| rno04510 |
Focal adhesion |
7 |
 |
| rno04512 |
ECM-receptor interaction |
7 |
 |
| rno05165 |
Human papillomavirus infection |
7 |
 |
| rno04974 |
Protein digestion and absorption |
6 |
 |
Genes directly connected with Fbn2 on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
Entrez Gene ID* |
| 4.3 |
Col2a1 |
collagen type II alpha 1 chain |
[detail] |
25412 |
| 4.2 |
Nrk |
Nik related kinase |
[detail] |
315907 |
| 4.2 |
Lama4 |
laminin subunit alpha 4 |
[detail] |
309816 |
| 3.9 |
Asxl3 |
ASXL transcriptional regulator 3 |
[detail] |
307555 |
|
Coexpressed
gene list |
[Coexpressed gene list for Fbn2]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
Fbn2 Gene
