| functional annotation |
| Function |
serine peptidase inhibitor, Kunitz type 1 |
|
| GO BP |
|
GO:0060670 [list] [network] branching involved in labyrinthine layer morphogenesis
|
(12 genes)
|
IEA
|
 |
|
GO:2000178 [list] [network] negative regulation of neural precursor cell proliferation
|
(21 genes)
|
IEA
|
|
|
GO:0060674 [list] [network] placenta blood vessel development
|
(29 genes)
|
IEA
|
|
|
GO:0045687 [list] [network] positive regulation of glial cell differentiation
|
(42 genes)
|
IEA
|
|
|
GO:0001843 [list] [network] neural tube closure
|
(88 genes)
|
IEA
|
|
|
GO:0071773 [list] [network] cellular response to BMP stimulus
|
(94 genes)
|
IEA
|
|
|
GO:0010951 [list] [network] negative regulation of endopeptidase activity
|
(255 genes)
|
IEA
|
|
|
GO:0030198 [list] [network] extracellular matrix organization
|
(379 genes)
|
IEA
|
|
|
| GO CC |
|
| GO MF |
|
GO:0004867 [list] [network] serine-type endopeptidase inhibitor activity
|
(98 genes)
|
IEA
|
|
|
| KEGG |
hsa05202 [list] [network] Transcriptional misregulation in cancer (192 genes) |
 |
| hsa05215 [list] [network] Prostate cancer (97 genes) |
|
| Protein |
NP_001027539.1
NP_001373802.1
NP_001373803.1
NP_001373804.1
NP_003701.1
NP_857593.1
|
| BLAST |
NP_001027539.1
NP_001373802.1
NP_001373803.1
NP_001373804.1
NP_003701.1
NP_857593.1
|
| Orthologous |
[Ortholog page]
Spint1 (mmu)
Spint1 (rno)
spint1a (dre)
SPINT1 (gga)
SPINT1 (cfa)
SPINT1 (mcc)
spint1b (dre)
SPINT1 (fca)
|
Subcellular
localization
wolf |
|
plas 7,
pero 1,
extr 1
|
(predict for NP_001027539.1)
|
|
plas 7,
pero 1,
extr 1
|
(predict for NP_001373802.1)
|
|
plas 7,
pero 1,
extr 1,
E.R. 1,
mito_pero 1,
cyto_pero 1
|
(predict for NP_001373803.1)
|
|
plas 7,
pero 1,
extr 1,
E.R. 1,
mito_pero 1,
cyto_pero 1
|
(predict for NP_001373804.1)
|
|
plas 7,
pero 1,
extr 1
|
(predict for NP_003701.1)
|
|
plas 7,
pero 1,
extr 1
|
(predict for NP_857593.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| hsa04670 |
Leukocyte transendothelial migration |
4 |
 |
| hsa04514 |
Cell adhesion molecules |
3 |
 |
| hsa04530 |
Tight junction |
3 |
 |
| hsa05130 |
Pathogenic Escherichia coli infection |
3 |
 |
| hsa05202 |
Transcriptional misregulation in cancer |
2 |
 |
Genes directly connected with SPINT1 on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
CoexPub |
Entrez Gene ID* |
| 11.0 |
ST14 |
ST14 transmembrane serine protease matriptase |
[detail] |
12 |
6768 |
| 9.3 |
CLDN7 |
claudin 7 |
[detail] |
4 |
1366 |
| 8.1 |
PRSS8 |
serine protease 8 |
[detail] |
22 |
5652 |
| 7.3 |
SPINT2 |
serine peptidase inhibitor, Kunitz type 2 |
[detail] |
40 |
10653 |
| 6.0 |
F11R |
F11 receptor |
[detail] |
2 |
50848 |
| 5.1 |
JUP |
junction plakoglobin |
[detail] |
0 |
3728 |
| 4.9 |
RAB11FIP1 |
RAB11 family interacting protein 1 |
[detail] |
0 |
80223 |
| 4.9 |
MAPK13 |
mitogen-activated protein kinase 13 |
[detail] |
0 |
5603 |
| 4.6 |
CYP2S1 |
cytochrome P450 family 2 subfamily S member 1 |
[detail] |
0 |
29785 |
| 4.5 |
MAP7 |
microtubule associated protein 7 |
[detail] |
0 |
9053 |
| 4.5 |
GALNT6 |
polypeptide N-acetylgalactosaminyltransferase 6 |
[detail] |
0 |
11226 |
|
Coexpressed
gene list |
[Coexpressed gene list for SPINT1]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
SPINT1 Gene
