[][] hsa  PRSS3 Gene
functional annotation
Function   serine protease 3
GO BP
GO:0009235 [list] [network] cobalamin metabolic process  (21 genes)  TAS  
GO:0031638 [list] [network] zymogen activation  (49 genes)  IDA  
GO:0043542 [list] [network] endothelial cell migration  (67 genes)  IMP  
GO:0007586 [list] [network] digestion  (114 genes)  TAS  
GO:0019730 [list] [network] antimicrobial humoral response  (131 genes)  TAS  
GO:0043312 [list] [network] neutrophil degranulation  (484 genes)  TAS  
GO:0006508 [list] [network] proteolysis  (1289 genes)  IBA IDA NAS  
GO CC
GO:1904724 [list] [network] tertiary granule lumen  (55 genes)  TAS  
GO:0005615 [list] [network] extracellular space  (3622 genes)  IBA IDA  
GO:0005576 [list] [network] extracellular region  (4632 genes)  TAS  
GO MF
GO:0004252 [list] [network] serine-type endopeptidase activity  (168 genes)  IBA IDA  
GO:0005509 [list] [network] calcium ion binding  (713 genes)  IDA  
GO:0005515 [list] [network] protein binding  (13898 genes)  IPI  
KEGG hsa04080 [list] [network] Neuroactive ligand-receptor interaction (353 genes)
hsa04972 [list] [network] Pancreatic secretion (102 genes)
hsa04974 [list] [network] Protein digestion and absorption (103 genes)
hsa05164 [list] [network] Influenza A (171 genes)
Protein NP_001184026.3  NP_001184027.1  NP_002762.3  NP_031369.3  XP_011516267.1 
BLAST NP_001184026.3  NP_001184027.1  NP_002762.3  NP_031369.3  XP_011516267.1 
Orthologous [Ortholog page] PRSS1 (hsa)PRSS2 (hsa)KLK7 (hsa)KLK6 (hsa)KLK8 (hsa)Klk6 (mmu)Prss2 (mmu)Prss3 (mmu)Try4 (mmu)Klk7 (mmu)Prss1 (rno)Prss2 (rno)KLK13 (hsa)Klk6 (rno)CG6041 (dme)CG31954 (dme)CG3355 (dme)Try29F (dme)CG8299 (dme)CG16998 (dme)CG32374 (dme)CG12951 (dme)CG16749 (dme)KLK14 (hsa)KLK15 (hsa)CG18735 (dme)prss1 (dre)2210010C04Rik (mmu)1810009J06Rik (mmu)Try5 (mmu)Prss1 (mmu)Klk8 (mmu)Prss3b (rno)LOC286960 (rno)Klk13 (rno)Klk7 (rno)Klk14 (rno)LOC312273 (rno)Klk15 (mmu)Klk14 (mmu)CG32376 (dme)CG32755 (dme)CG32808 (dme)prss59.1 (dre)Prss3 (rno)PRSS2 (gga)PRSS3 (gga)Try10 (rno)Try10 (mmu)Gm5771 (mmu)zgc:92590 (dre)LOC475521 (cfa)KLK6 (cfa)LOC480822 (cfa)KLK14 (cfa)KLK8 (cfa)LOC560023 (dre)zmp:0000001088 (dre)si:dkey-33m11.8 (dre)KLK7 (cfa)Klk13 (mmu)LOC683849 (rno)PRSS2 (mcc)PRSS1 (mcc)LOC698859 (mcc)LOC699109 (mcc)LOC716882 (mcc)KLK15 (mcc)KLK8 (mcc)KLK6 (mcc)KLK7 (mcc)KLK14 (mcc)LOC768817 (gga)KLK7 (gga)yps1 (spo)sxa1 (spo)Gm2663 (mmu)Gm10334 (mmu)zgc:171509 (dre)prss59.2 (dre)PRSS2 (cfa)KLK13 (cfa)LOC101085453 (fca)LOC101085707 (fca)KLK6 (fca)KLK7 (fca)KLK8 (fca)KLK14 (fca)LOC101750376 (gga)Klk15 (rno)LOC102554637 (rno)KLK13 (fca)Try5 (rno)LOC103908930 (dre)KLK15 (fca)KLK13 (mcc)LOC106996172 (mcc)LOC107049069 (gga)LOC107054567 (gga)LOC114677048 (mcc)LOC119870314 (cfa)LOC121106429 (gga)LOC121107389 (gga)LOC121107405 (gga)LOC121109011 (gga)LOC121109012 (gga)LOC121109423 (gga)LOC121109427 (gga)LOC121112850 (gga)
Subcellular
localization
wolf
cyto 5,  cyto_nucl 3,  cyto_pero 3,  mito 3,  nucl 1,  E.R._mito 1  (predict for NP_001184026.3)
extr 4,  cyto 3,  mito 1,  lyso 1,  mito_nucl 1  (predict for NP_001184027.1)
extr 10  (predict for NP_002762.3)
extr 5,  mito 4  (predict for NP_031369.3)
cyto_nucl 5,  cyto 4,  nucl 4,  extr 2  (predict for XP_011516267.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04080 Neuroactive ligand-receptor interaction 3
hsa04972 Pancreatic secretion 3
hsa04974 Protein digestion and absorption 3
hsa05164 Influenza A 3
hsa00564 Glycerophospholipid metabolism 2
Genes directly connected with PRSS3 on the network
coex z* Locus Function* Coexpression
detail
CoexPub Entrez Gene ID*
13.5 PRSS2 serine protease 2 [detail] 13 5645
8.1 PRSS1 serine protease 1 [detail] 0 5644
5.1 LCE3D late cornified envelope 3D [detail] 0 84648
5.0 PLEK2 pleckstrin 2 [detail] 0 26499
4.8 MALL mal, T cell differentiation protein like [detail] 0 7851
Coexpressed
gene list
[Coexpressed gene list for PRSS3]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 5646    
Refseq ID (protein) NP_001184026.3 
NP_001184027.1 
NP_002762.3 
NP_031369.3 
XP_011516267.1 


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