| functional annotation |
| Function |
RUNX family transcription factor 2b |
|
| GO BP |
|
GO:0002062 [list] [network] chondrocyte differentiation
|
(21 genes)
|
IBA
IMP
|
 |
|
GO:0001503 [list] [network] ossification
|
(71 genes)
|
IBA
|
|
|
GO:0051216 [list] [network] cartilage development
|
(139 genes)
|
IMP
|
|
|
GO:0009953 [list] [network] dorsal/ventral pattern formation
|
(148 genes)
|
IGI
|
|
|
GO:0045595 [list] [network] regulation of cell differentiation
|
(410 genes)
|
IBA
|
|
|
GO:0030097 [list] [network] hemopoiesis
|
(455 genes)
|
IBA
|
|
|
GO:0045893 [list] [network] positive regulation of transcription, DNA-templated
|
(483 genes)
|
IDA
|
|
|
GO:0030182 [list] [network] neuron differentiation
|
(855 genes)
|
IBA
|
|
|
GO:0006357 [list] [network] regulation of transcription by RNA polymerase II
|
(1731 genes)
|
IBA
|
|
|
GO:0006355 [list] [network] regulation of transcription, DNA-templated
|
(2255 genes)
|
IEA
|
|
|
| GO CC |
|
| GO MF |
|
GO:0042809 [list] [network] vitamin D receptor binding
|
(3 genes)
|
IPI
|
|
|
GO:0000978 [list] [network] RNA polymerase II cis-regulatory region sequence-specific DNA binding
|
(988 genes)
|
IBA
|
|
|
GO:0000981 [list] [network] DNA-binding transcription factor activity, RNA polymerase II-specific
|
(1261 genes)
|
IBA
|
|
|
GO:0003700 [list] [network] DNA-binding transcription factor activity
|
(1358 genes)
|
IDA
IEA
ISS
|
|
|
GO:0005524 [list] [network] ATP binding
|
(1578 genes)
|
IEA
|
|
|
GO:0003677 [list] [network] DNA binding
|
(2079 genes)
|
IEA
|
|
|
| KEGG |
|
|
| Protein |
NP_998027.2
XP_021324060.1
|
| BLAST |
NP_998027.2
XP_021324060.1
|
| Orthologous |
[Ortholog page]
RUNX2 (hsa)
RUNX1 (hsa)
RUNX3 (hsa)
Runx2 (mmu)
Runx1 (mmu)
Runx3 (mmu)
lz (dme)
RunxB (dme)
run (dme)
Runx1 (rno)
runx1 (dre)
runx3 (dre)
Runx3 (rno)
rnt-1 (cel)
Runx2 (rno)
RUNX2 (gga)
RUNX1 (gga)
runx2a (dre)
RUNX2 (cfa)
RUNX1 (cfa)
RUNX1 (mcc)
RUNX2 (mcc)
RUNX3 (mcc)
RUNX3 (gga)
cao2 (spo)
cao1 (spo)
RunxA (dme)
RUNX3 (fca)
RUNX1 (fca)
RUNX2 (fca)
RUNX3 (cfa)
|
Subcellular
localization
wolf |
|
nucl 7,
cyto_nucl 5,
cyto 2
|
(predict for NP_998027.2)
|
|
nucl 6,
cyto_nucl 4,
cyto 2,
extr 1,
mito 1
|
(predict for XP_021324060.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| dre04510 |
Focal adhesion |
3 |
 |
| dre04512 |
ECM-receptor interaction |
3 |
 |
| dre04218 |
Cellular senescence |
2 |
 |
| dre04530 |
Tight junction |
2 |
 |
Genes directly connected with runx2b on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
Entrez Gene ID* |
| 5.0 |
wt1a |
WT1 transcription factor a |
[detail] |
30245 |
| 4.4 |
col27a1a |
collagen, type XXVII, alpha 1a |
[detail] |
100004688 |
| 4.2 |
atp10b |
ATPase phospholipid transporting 10B |
[detail] |
563932 |
|
Coexpressed
gene list |
[Coexpressed gene list for runx2b]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
runx2b Gene
