[←][→] hsa  LOX Gene
functional annotation
Function   lysyl oxidase  
GO BP
GO:0035906 [list] [network] descending aorta development  (1 genes)  IEA  
GO:0018057 [list] [network] peptidyl-lysine oxidation  (5 genes)  IBA IDA  
GO:0035905 [list] [network] ascending aorta development  (5 genes)  IEA  
GO:0035791 [list] [network] platelet-derived growth factor receptor-beta signaling pathway  (7 genes)  IEA  
GO:1903010 [list] [network] regulation of bone development  (7 genes)  IEA  
GO:2000586 [list] [network] regulation of platelet-derived growth factor receptor-beta signaling pathway  (8 genes)  IEA  
GO:0048251 [list] [network] elastic fiber assembly  (10 genes)  IEA  
GO:0046716 [list] [network] muscle cell cellular homeostasis  (19 genes)  IEA  
GO:1900120 [list] [network] regulation of receptor binding  (22 genes)  IEA  
GO:0016202 [list] [network] regulation of striated muscle tissue development  (37 genes)  IEA  
GO:0043491 [list] [network] protein kinase B signaling  (37 genes)  IEA  
GO:0030282 [list] [network] bone mineralization  (50 genes)  IEA  
GO:0045652 [list] [network] regulation of megakaryocyte differentiation  (83 genes)  IEA  
GO:1990869 [list] [network] cellular response to chemokine  (90 genes)  IEA  
GO:0030199 [list] [network] collagen fibril organization  (101 genes)  IBA TAS  
GO:0071897 [list] [network] DNA biosynthetic process  (112 genes)  IEA  
GO:0001649 [list] [network] osteoblast differentiation  (126 genes)  IEA  
GO:0017015 [list] [network] regulation of transforming growth factor beta receptor signaling pathway  (133 genes)  IEA  
GO:0055001 [list] [network] muscle cell development  (150 genes)  IEA  
GO:0030324 [list] [network] lung development  (172 genes)  IEA  
GO:0061448 [list] [network] connective tissue development  (199 genes)  IEA  
GO:0060326 [list] [network] cell chemotaxis  (205 genes)  IEA  
GO:0048545 [list] [network] response to steroid hormone  (285 genes)  IEA  
GO:0030198 [list] [network] extracellular matrix organization  (379 genes)  TAS  
GO:0042493 [list] [network] response to drug  (385 genes)  IEA  
GO:0048514 [list] [network] blood vessel morphogenesis  (410 genes)  ISS  
GO:0042060 [list] [network] wound healing  (455 genes)  IEA  
GO:0007507 [list] [network] heart development  (537 genes)  IEA  
GO:0001932 [list] [network] regulation of protein phosphorylation  (1118 genes)  IEA  
GO:0042981 [list] [network] regulation of apoptotic process  (1534 genes)  IEA  
GO:0006464 [list] [network] cellular protein modification process  (2960 genes)  TAS  
GO:0010468 [list] [network] regulation of gene expression  (5501 genes)  IEA  
GO CC
GO:0005581 [list] [network] collagen trimer  (87 genes)  IEA  
GO:0031012 [list] [network] extracellular matrix  (570 genes)  IEA  
GO:0005615 [list] [network] extracellular space  (3622 genes)  IBA IDA  
GO:0005576 [list] [network] extracellular region  (4632 genes)  ISS TAS  
GO:0005634 [list] [network] nucleus  (8115 genes)  IEA  
GO MF
GO:0004720 [list] [network] protein-lysine 6-oxidase activity  (5 genes)  IBA IDA ISS  
GO:0005507 [list] [network] copper ion binding  (61 genes)  IEA  
GO:0005518 [list] [network] collagen binding  (69 genes)  IDA  
GO:0005515 [list] [network] protein binding  (13898 genes)  IPI  
KEGG
Protein NP_001171573.1  NP_001304002.1  NP_002308.2 
BLAST NP_001171573.1  NP_001304002.1  NP_002308.2 
Orthologous [Ortholog page] Lox (mmu)  Lox (rno)  LOX (gga)  loxa (dre)  LOX (cfa)  LOX (mcc)  LOX (fca) 
Subcellular
localization
wolf
extr 6,  cyto_nucl 2,  nucl 2,  cyto 2  (predict for NP_001171573.1)
extr 7,  cyto 2,  nucl 1  (predict for NP_001304002.1)
extr 9,  lyso 1  (predict for NP_002308.2)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04974 Protein digestion and absorption 5
hsa04611 Platelet activation 3
hsa04926 Relaxin signaling pathway 3
hsa04933 AGE-RAGE signaling pathway in diabetic complications 3
hsa05146 Amoebiasis 3
Genes directly connected with LOX on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
6.4 PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 [detail] 20 5352
5.8 CCDC80 coiled-coil domain containing 80 [detail] 0 151887
5.5 FBN1 fibrillin 1 [detail] 13 2200
Coexpressed
gene list		 [Coexpressed gene list for LOX]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 4015      
Refseq ID (protein) NP_001171573.1 
NP_001304002.1 
NP_002308.2 


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