| functional annotation |
| Function |
dopamine receptor D2a |
|
| GO BP |
|
GO:0051481 [list] [network] negative regulation of cytosolic calcium ion concentration
|
(6 genes)
|
IBA
|
 |
|
GO:0051967 [list] [network] negative regulation of synaptic transmission, glutamatergic
|
(6 genes)
|
IBA
|
|
|
GO:0007195 [list] [network] adenylate cyclase-inhibiting dopamine receptor signaling pathway
|
(7 genes)
|
IBA
IEA
|
|
|
GO:0007194 [list] [network] negative regulation of adenylate cyclase activity
|
(8 genes)
|
IBA
|
|
|
GO:1901386 [list] [network] negative regulation of voltage-gated calcium channel activity
|
(10 genes)
|
IBA
|
|
|
GO:0060158 [list] [network] phospholipase C-activating dopamine receptor signaling pathway
|
(14 genes)
|
IBA
|
|
|
GO:0043266 [list] [network] regulation of potassium ion transport
|
(24 genes)
|
IBA
|
|
|
GO:0014059 [list] [network] regulation of dopamine secretion
|
(25 genes)
|
IBA
|
|
|
GO:0071880 [list] [network] adenylate cyclase-activating adrenergic receptor signaling pathway
|
(25 genes)
|
IBA
|
|
|
GO:0007212 [list] [network] dopamine receptor signaling pathway
|
(26 genes)
|
ISS
|
|
|
GO:0051482 [list] [network] positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
|
(30 genes)
|
IBA
|
|
|
GO:0007186 [list] [network] G protein-coupled receptor signaling pathway
|
(993 genes)
|
IEA
|
|
|
GO:0007165 [list] [network] signal transduction
|
(3263 genes)
|
IEA
|
|
|
| GO CC |
|
GO:0099056 [list] [network] integral component of presynaptic membrane
|
(6 genes)
|
IBA
|
|
|
GO:0098978 [list] [network] glutamatergic synapse
|
(23 genes)
|
IBA
|
|
|
GO:0005887 [list] [network] integral component of plasma membrane
|
(1125 genes)
|
IBA
|
|
|
GO:0016021 [list] [network] integral component of membrane
|
(6086 genes)
|
IEA
ISS
|
|
|
GO:0016020 [list] [network] membrane
|
(7959 genes)
|
IEA
|
|
|
| GO MF |
|
GO:0001591 [list] [network] dopamine neurotransmitter receptor activity, coupled via Gi/Go
|
(6 genes)
|
IBA
ISS
|
|
|
GO:0004952 [list] [network] dopamine neurotransmitter receptor activity
|
(9 genes)
|
IEA
|
|
|
GO:0004930 [list] [network] G protein-coupled receptor activity
|
(796 genes)
|
IBA
IEA
|
|
|
| KEGG |
dre04080 [list] [network] Neuroactive ligand-receptor interaction (586 genes) |
 |
| dre04540 [list] [network] Gap junction (132 genes) |
|
| Protein |
NP_898891.1
XP_005157558.1
XP_009289892.1
|
| BLAST |
NP_898891.1
XP_005157558.1
XP_009289892.1
|
| Orthologous |
[Ortholog page]
DRD2 (hsa)
Drd2 (mmu)
Drd2 (rno)
DRD2 (cfa)
DRD2 (gga)
DRD2 (mcc)
DRD2 (fca)
|
Subcellular
localization
wolf |
|
plas 10
|
(predict for NP_898891.1)
|
|
plas 10
|
(predict for XP_005157558.1)
|
|
plas 10
|
(predict for XP_009289892.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
Genes directly connected with drd2a on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
Entrez Gene ID* |
| 5.0 |
ubn1 |
ubinuclein 1 |
[detail] |
566684 |
| 4.6 |
gpr185b |
G protein-coupled receptor 185 b |
[detail] |
565203 |
| 4.4 |
slc4a10b |
solute carrier family 4 member 10b |
[detail] |
557642 |
| 3.4 |
stc2b |
stanniocalcin 2b |
[detail] |
100884139 |
|
Coexpressed
gene list |
[Coexpressed gene list for drd2a]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
drd2a Gene
