[][] rno  Gdf5 Gene
functional annotation
Function   growth differentiation factor 5
GO BP
GO:0043932 [list] [network] ossification involved in bone remodeling  (5 genes)  IEP  
GO:0060591 [list] [network] chondroblast differentiation  (6 genes)  ISO  
GO:2001054 [list] [network] negative regulation of mesenchymal cell apoptotic process  (13 genes)  ISO  
GO:0032332 [list] [network] positive regulation of chondrocyte differentiation  (21 genes)  ISO  
GO:0032331 [list] [network] negative regulation of chondrocyte differentiation  (24 genes)  ISO  
GO:0060390 [list] [network] regulation of SMAD protein signal transduction  (28 genes)  ISO  
GO:0030513 [list] [network] positive regulation of BMP signaling pathway  (40 genes)  ISO  
GO:0035136 [list] [network] forelimb morphogenesis  (45 genes)  ISO  
GO:0035137 [list] [network] hindlimb morphogenesis  (46 genes)  ISO  
GO:0010862 [list] [network] positive regulation of pathway-restricted SMAD protein phosphorylation  (49 genes)  IBA  
GO:0060395 [list] [network] SMAD protein signal transduction  (77 genes)  IBA ISO  
GO:0040014 [list] [network] regulation of multicellular organism growth  (88 genes)  ISO  
GO:0030509 [list] [network] BMP signaling pathway  (90 genes)  IBA  
GO:0045666 [list] [network] positive regulation of neuron differentiation  (115 genes)  IDA  
GO:0030326 [list] [network] embryonic limb morphogenesis  (145 genes)  ISO  
GO:0050680 [list] [network] negative regulation of epithelial cell proliferation  (152 genes)  ISO  
GO:0043524 [list] [network] negative regulation of neuron apoptotic process  (188 genes)  IDA  
GO:0007178 [list] [network] transmembrane receptor protein serine/threonine kinase signaling pathway  (208 genes)  ISO  
GO:0009612 [list] [network] response to mechanical stimulus  (344 genes)  IEP  
GO CC
GO:0005615 [list] [network] extracellular space  (1510 genes)  IBA NAS  
GO MF
GO:0036122 [list] [network] BMP binding  (16 genes)  ISO  
GO:0008083 [list] [network] growth factor activity  (145 genes)  IEA  
GO:0005125 [list] [network] cytokine activity  (190 genes)  IBA  
GO:0005102 [list] [network] signaling receptor binding  (1488 genes)  IMP  
GO:0042802 [list] [network] identical protein binding  (2232 genes)  ISO  
KEGG rno04060 [list] [network] Cytokine-cytokine receptor interaction (269 genes)
rno04350 [list] [network] TGF-beta signaling pathway (94 genes)
rno04390 [list] [network] Hippo signaling pathway (158 genes)
Protein XP_003749648.1 
BLAST XP_003749648.1 
Orthologous [Ortholog page] GDF5 (hsa)Gdf5 (mmu)GDF5 (gga)GDF5 (cfa)GDF5 (mcc)gdf5 (dre)GDF5 (fca)
Subcellular
localization
wolf
extr 6,  E.R. 1,  mito 1,  pero 1,  mito_pero 1,  nucl 1,  E.R._golg 1  (predict for XP_003749648.1)
Gene coexpression
Network*for
coexpressed
genes
Coexpressed
gene list
[Coexpressed gene list for Gdf5]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 252835    
Refseq ID (protein) XP_003749648.1 


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