[←][→] mmu  Prdx1 Gene
functional annotation
Function   peroxiredoxin 1  
GO BP
GO:0019430 [list] [network] removal of superoxide radicals  (12 genes)  IBA IMP  
GO:0042267 [list] [network] natural killer cell mediated cytotoxicity  (26 genes)  IMP  
GO:0042744 [list] [network] hydrogen peroxide catabolic process  (27 genes)  IBA ISO  
GO:0045454 [list] [network] cell redox homeostasis  (30 genes)  IBA  
GO:0030101 [list] [network] natural killer cell activation  (67 genes)  ISO  
GO:1901222 [list] [network] regulation of NIK/NF-kappaB signaling  (97 genes)  IMP  
GO:0034101 [list] [network] erythrocyte homeostasis  (118 genes)  IMP  
GO:0000302 [list] [network] response to reactive oxygen species  (154 genes)  IMP  
GO:0032872 [list] [network] regulation of stress-activated MAPK cascade  (191 genes)  IMP  
GO:0006979 [list] [network] response to oxidative stress  (342 genes)  IBA IDA IMP ISO  
GO:0008283 [list] [network] cell population proliferation  (578 genes)  IMP  
GO:0045321 [list] [network] leukocyte activation  (588 genes)  IBA  
GO:0033554 [list] [network] cellular response to stress  (1482 genes)  IBA  
GO CC
GO:0005782 [list] [network] peroxisomal matrix  (26 genes)  ISO  
GO:0000791 [list] [network] euchromatin  (46 genes)  ISO  
GO:0043209 [list] [network] myelin sheath  (215 genes)  HDA  
GO:0005759 [list] [network] mitochondrial matrix  (276 genes)  ISO  
GO:0005730 [list] [network] nucleolus  (895 genes)  ISO  
GO:0005739 [list] [network] mitochondrion  (1890 genes)  HDA  
GO:0005829 [list] [network] cytosol  (3785 genes)  IBA ISO TAS  
GO:0005634 [list] [network] nucleus  (7226 genes)  ISO  
GO:0005737 [list] [network] cytoplasm  (11434 genes)  ISO  
GO MF
GO:0008379 [list] [network] thioredoxin peroxidase activity  (6 genes)  IBA ISO  
GO:0051920 [list] [network] peroxiredoxin activity  (8 genes)  ISO  
GO:0004601 [list] [network] peroxidase activity  (55 genes)  ISO  
GO:0016209 [list] [network] antioxidant activity  (85 genes)  IEA  
GO:0020037 [list] [network] heme binding  (162 genes)  ISO  
GO:0016491 [list] [network] oxidoreductase activity  (801 genes)  IEA  
GO:0042802 [list] [network] identical protein binding  (2357 genes)  IPI ISO  
GO:0005515 [list] [network] protein binding  (9507 genes)  IPI  
KEGG mmu04146 [list] [network] Peroxisome (86 genes)
mmu05146 [list] [network] Amoebiasis (107 genes)
Protein NP_035164.1 
BLAST NP_035164.1 
Orthologous [Ortholog page] PRDX1 (hsa)  PRDX2 (hsa)  PRDX4 (hsa)  PRDX3 (hsa)  Prdx3 (mmu)  Prdx2 (mmu)  Prdx2 (rno)  CG6888 (dme)  Prx3 (dme)  Prdx4 (mmu)  Jafrac2 (dme)  Jafrac1 (dme)  Prdx3 (rno)  Prdx4 (rno)  Prdx1 (rno)  prdx-3 (cel)  prdx-2 (cel)  prdx3 (dre)  PRDX4 (gga)  PRDX1 (gga)  PRDX3 (gga)  PRDX1 (cfa)  PRDX3 (cfa)  prdx1 (dre)  prdx4 (dre)  PRDX4 (mcc)  PRDX3 (mcc)  PRDX1 (mcc)  PRDX2 (mcc)  prdx2 (dre)  TSA2 (sce)  TSA1 (sce)  Prdx1l1 (rno)  PRDX2 (cfa)  PRDX2 (fca)  PRDX3 (fca)  PRDX1 (fca)  PRDX4 (fca)  PRDX4 (cfa) 
Subcellular
localization
wolf
cyto 5,  cyto_nucl 4,  cyto_plas 3,  extr 2,  mito 1,  pero 1,  mito_pero 1  (predict for NP_035164.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu05012 Parkinson disease 12
mmu05014 Amyotrophic lateral sclerosis 12
mmu05022 Pathways of neurodegeneration - multiple diseases 12
mmu03050 Proteasome 11
mmu05010 Alzheimer disease 11
Genes directly connected with Prdx1 on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
9.5 Txn1 thioredoxin 1 [detail] 27 22166
9.2 Akr1a1 aldo-keto reductase family 1, member A1 (aldehyde reductase) [detail] 2 58810
8.9 Psma5 proteasome subunit alpha 5 [detail] 0 26442
8.4 Esd esterase D/formylglutathione hydrolase [detail] 0 13885
7.7 Cyb5a cytochrome b5 type A (microsomal) [detail] 1 109672
7.2 Skp1 S-phase kinase-associated protein 1 [detail] 0 21402
5.5 Pnp purine-nucleoside phosphorylase [detail] 0 18950
Coexpressed
gene list		 [Coexpressed gene list for Prdx1]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 18477      
Refseq ID (protein) NP_035164.1 


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