Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4   EFEMP2   EGF containing fibulin extracellular matrix protein 2 
 hsa-r.6   EFEMP2   EGF containing fibulin extracellular matrix protein 2 
 hsa-m.7   EFEMP2   EGF containing fibulin extracellular matrix protein 2 
 hsa-m2.4   EFEMP2   EGF containing fibulin extracellular matrix protein 2 
 hsa-u.4   FBLN5   fibulin 5 
 mcc-u.3   EFEMP2   EGF containing fibulin extracellular matrix protein 2 
 mcc-u.3   FBLN5   fibulin 5 
 mmu-u.4   Efemp2   epidermal growth factor-containing fibulin-like extracellular matrix protein 2 
 mmu-u.4   Fbln5   fibulin 5 
 rno-u.3   Fbln5   fibulin 5 
 rno-u.3   Efemp2   EGF containing fibulin extracellular matrix protein 2 
 cfa-u.3   FBLN5   fibulin 5 
 cfa-u.3   EFEMP2   EGF containing fibulin extracellular matrix protein 2 
 gga-u.3   FBLN5   fibulin 5 
 dre-u.3   si:ch73-173h19.3   si:ch73-173h19.3 
 dre-u.3   efemp2a   EGF containing fibulin extracellular matrix protein 2a 

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Top 50 coexpressed genes to EFEMP2 (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa4510   Focal adhesion  5 185 3.64
 hsa4512   ECM-receptor interaction  4 78 4.06
 hsa4022   cGMP-PKG signaling pathway  3 144 2.03
 hsa5165   Human papillomavirus infection  4 331 -
 hsa4151   PI3K-Akt signaling pathway  4 354 -

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hsa:EFEMP2 (EGF containing fibulin extracellular matrix protein 2) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-u.4
for
EFEMP2
hsa-r.6
for
EFEMP2
hsa-m.7
for
EFEMP2
hsa-m2.4
for
EFEMP2
hsa-u.4
for
FBLN5
mcc-u.3
for
EFEMP2
mcc-u.3
for
FBLN5
mmu-u.4
for
Efemp2
mmu-u.4
for
Fbln5
rno-u.3
for
Fbln5
rno-u.3
for
Efemp2
cfa-u.3
for
FBLN5
cfa-u.3
for
EFEMP2
gga-u.3
for
FBLN5
dre-u.3
for
si:ch73-173h19.3
dre-u.3
for
efemp2a
1 FKBP10 FKBP prolyl isomerase 10 60681 0 6.8 6.0
 2.3
 6.0
 0.9
 4.2
 2.2
 8.3
 3.6
 3.7
 8.1
 0.5
 2.0
 2.8
 0.5
 3.5
2 PCOLCE procollagen C-endopeptidase enhancer 5118 0 6.4 7.0
 3.5
 4.3
 3.5
 3.8
 3.0
 6.5
 5.9
 3.7
 6.9
 1.7
 4.1


3 CERCAM cerebral endothelial cell adhesion molecule 51148 0 6.0 4.9
 2.1
 5.7
 1.5
0.3
 0.8
 0.7
 3.5
0.7
 1.4
0.5
 1.9
1.3
 4.2
1.3
 1.6
1.5
 3.3
-0.2
 0.5
-0.3
 1.7
1.6
 3.1
2.4
4 AEBP1 AE binding protein 1 165 2 6.0 4.8
 2.8
 5.8
 3.5
 4.6
 2.9
 6.3
 3.8
 2.1
 5.1
 1.6
 4.1
 1.9

5 RCN3 reticulocalbin 3 57333 0 5.7 5.6
 2.8
 4.5
 2.2
 2.1
1.1
 2.6
1.5
 7.1
 2.7
 2.6
 7.9
 1.3
 4.5


6 GPX7 glutathione peroxidase 7 2882 0 5.3 3.9
 2.2
 5.5
 2.3
1.8
 2.5
1.3
 2.1
1.3
 6.9
3.8
 2.9
2.6
 1.5
1.3
 5.3
4.1
 -0.1
-1.1
 2.2
1.0
 1.6
1.1
 1.3
0.4
 2.9
1.3
7 MRC2 mannose receptor C type 2 9902 0 5.2 3.3
 2.7
 5.9
 3.4
0.3
 2.2
1.4
 2.5
1.8
 4.7
1.9
 4.0
3.4
 2.7
1.0
 2.9
0.8
 1.7
0.6
 2.0
2.0
 2.6
1.4
 1.0
1.0
 6.0
1.6
8 COPZ2 COPI coat complex subunit zeta 2 51226 0 5.2 4.7
 3.9
 4.5
 3.0
0.7
 3.5
0.7
 1.5
1.3
 3.9
0.1
 2.7
-0.3
 1.5
-0.3
 2.9
1.5
 1.6
 3.4
 -0.4
 0.3
-0.4
 1.0
0.6
9 LTBP3 latent transforming growth factor beta binding protein 3 4054 0 5.1 4.2
 1.9
 4.8
 2.1
 4.4
 1.1
 4.3
 3.0
 3.9
 3.4
 1.2
 1.9
2.7
 2.5
10 CTF1 cardiotrophin 1 1489 0 5.1 5.0
 2.5
 3.9
 1.3
 0.9
 0.7
 1.2
 0.6
 1.0
 0.3




11 MXRA8 matrix remodeling associated 8 54587 0 5.0 6.6
 2.5
 2.2
 2.3
 2.8
 2.1
 5.7
 5.4
 4.9
 3.7
 1.3
 3.3
 3.8
 2.9
1.4
 0.2
-0.1
12 THBS3 thrombospondin 3 7059 0 5.0 4.7
 2.6
 4.1
 0.3
 4.7
 1.5
 2.7
 1.2
 0.2
 2.3
 2.3
 3.2
1.3
0.1
 1.3
0.9
13 MDK midkine 4192 0 4.9 3.8
 1.2
 4.9
 -0.4
 3.0
 0.0
 3.5
 0.8
 1.9
 3.3
 -0.2
 3.0
 0.3
 1.1
0.2
 0.3
-0.0
14 TPM2 tropomyosin 2 7169 0 4.9 5.3
 2.2
 3.4
 2.1
1.4
 7.6
2.8
 1.5
-0.0
 2.5
1.5
 2.4
0.4
 2.1
-0.3
 2.9
0.4
 0.5
0.3
 2.9
1.5
 1.4
-0.2
 0.9
0.2
 3.9
1.1
15 LOXL4 lysyl oxidase like 4 84171 0 4.9 4.7
 1.3
 3.9
 0.9
0.9
 2.9
1.2
 1.4
1.4
 7.2
3.4
 3.3
2.0
 3.3
2.6
 4.8
2.4
 2.5
1.0
 2.7
1.2
 3.7
3.0
 1.8
1.1
 5.0
2.2
16 EMILIN1 elastin microfibril interfacer 1 11117 7 4.8 4.0
 2.4
 4.4
 1.8
 4.0
 1.8
 4.3
 2.1
 1.9
 4.4
 0.2
 1.7
 1.1
 2.4
1.6
 3.2
2.9
17 SLC12A4 solute carrier family 12 member 4 6560 0 4.8 4.9
 1.0
 3.5
 1.7
0.6
 2.4
0.4
 1.2
1.1
 4.1
0.9
 1.4
0.5
 0.8
0.2
 2.0
0.7
 1.9
-0.2
 0.8
-0.1
 -0.0
-0.9
 0.7
0.5
 0.7
0.3
18 CLIP3 CAP-Gly domain containing linker protein 3 25999 0 4.7 3.7
 1.6
 4.5
 2.6
1.2
 2.0
0.4
 1.3
-0.2
 2.3
1.0
 1.3
-0.2
 0.6
-1.1
 1.1
-1.0
 0.6
-0.1
 2.2
-0.1
 -0.1
 0.2
0.2
 -0.8
-1.0
19 SERPINH1 serpin family H member 1 871 0 4.7 3.8
 2.0
 4.3
 1.5
 2.4
 0.6
 6.7
 3.2
 3.4
 5.0
 1.3
 0.9
 3.1
 2.3
0.7
 3.0
1.2
20 TGFB1I1 transforming growth factor beta 1 induced transcript 1 7041 0 4.6 4.7
 2.4
 3.4
 2.3
-0.3
 2.6
1.9
 1.5
1.3
 5.6
0.3
 3.0
2.6
 2.3
2.2
 4.0
1.9
 1.3
1.0
 2.8
0.1
 1.6
1.0
 1.3
1.1
 1.8
1.3
21 COX7A1 cytochrome c oxidase subunit 7A1 1346 0 4.6 3.5
 2.5
 4.5
 1.8
1.4
 2.5
0.2
 1.0
0.3
 0.2
-0.4
 0.0
-0.3
 0.4
 0.4
 0.4
-2.1
 1.3
-1.4
 0.5
0.1
 0.3
 -0.2
-0.2
22 SCARF2 scavenger receptor class F member 2 91179 0 4.6 4.4
 2.0
 3.7
 2.8
 3.4
 1.4
 5.8
 4.6
 3.5
 3.1
 0.8
 2.9
 1.6
 2.3
 3.3
23 TAGLN transgelin 6876 1 4.6 4.8
 2.1
 3.2
 2.6
2.4
 3.7
1.6
 2.0
1.6
 3.5
2.7
 4.8
2.3
 3.6
2.1
 3.4
2.6
 1.9
1.4
 3.4
2.3
 2.6
1.2
 2.2
1.1
 1.6
1.3
24 LAMB2 laminin subunit beta 2 3913 0 4.6 4.1
 2.6
 4.0
 2.1
1.5
 2.1
1.6
 2.4
0.5
 3.8
2.9
 3.3
2.3
 2.9
1.2
 3.2
2.0
 1.9
1.2
 1.8
0.9
 2.7
0.6
 2.4
1.5
 3.7
2.8
25 ARHGEF25 Rho guanine nucleotide exchange factor 25 115557 0 4.5 4.1
 0.7
 3.8
 1.8
 1.0
 0.1
 3.8
 1.2
 1.8
 4.2
 1.9
 2.1
1.0
1.0
 2.0
-0.5
26 ARHGEF17 Rho guanine nucleotide exchange factor 17 9828 0 4.4 3.1
 2.0
 4.7
 1.4
 1.2
 -0.6
 3.4
 1.1
 0.3
 2.5
 0.6
 1.5
 1.5
 -0.1
 1.5
27 MYL9 myosin light chain 9 10398 0 4.4 4.0
 2.4
 3.7
 2.7
1.4
 2.6
0.4
 1.3
1.2
 3.1
1.5
 4.7
1.9
 3.7
0.8
 2.4
1.7
 1.2
1.0
 1.1
0.6
 1.5
0.9
 0.7
0.7
 2.5
1.4
28 LOX lysyl oxidase 4015 0 4.4 4.0
 1.9
 3.8
 4.5
 1.7
 4.0
 2.8
 6.8
 3.7
 2.6
 1.3
 0.5
 4.2
 2.5
 1.8
29 LCAT lecithin-cholesterol acyltransferase 3931 0 4.4 4.4
 1.6
 3.3
 1.6
0.4
 4.1
-2.2
 -0.1
-0.4
 1.4
1.0
 0.8
0.3
 0.5
0.2
 1.7
1.1
 0.6
0.1
 0.6
0.1
 0.6
0.0
 0.8
-0.9
 0.9
-1.5
30 FCGRT Fc fragment of IgG receptor and transporter 2217 0 4.4 4.5
 2.0
 3.2
 1.9
 2.1
 1.8
 2.2
 2.9
 2.2
 1.8
 3.2
 1.8


31 VAMP5 vesicle associated membrane protein 5 10791 0 4.3 3.7
 2.1
 3.9
 1.2
 2.7
 2.5
 0.4
 1.2
 0.2
 0.8
 0.9
 1.0
-0.9
 0.3
32 BGN biglycan 633 0 4.2 3.2
 2.7
 4.3
 5.1
3.1
 2.3
2.1
 4.1
3.0
 4.3
1.8
 8.5
4.4
 6.2
2.9
 3.4
2.0
 2.7
2.1
 3.3
2.2
 3.8
2.4
 3.3
2.0
 1.5
1.2
33 P3H3 prolyl 3-hydroxylase 3 10536 0 4.2 4.1
 2.5
 3.3
 1.7
 3.9
 -0.0
 6.3
 4.0
 2.0
 7.0
 0.0
 5.2
 2.8

34 LTBP2 latent transforming growth factor beta binding protein 2 4053 0 4.2 3.7
 1.9
 3.6
 4.5
 1.5
 4.5
 1.8
 4.5
 3.5
 2.3
 1.1
 1.1
 1.6

35 CCDC80 coiled-coil domain containing 80 151887 0 4.2 4.5
 2.3
 2.8
 2.7
 1.7
 2.1
 2.8
 3.4
 3.9
 2.6
 0.9
 2.0
 1.5
 0.3
 0.9
36 FGF11 fibroblast growth factor 11 2256 0 4.2 3.9
 1.4
 3.5
 -1.3
 -0.3
 -1.1
 2.0
 0.4
 -0.4
 -0.7
 0.2
 0.8


37 COL6A1 collagen type VI alpha 1 chain 1291 0 4.2 4.1
 1.7
 3.3
 2.6
 2.6
 2.1
 3.1
 4.7
 2.6
 4.3
 1.7
 4.0
 3.1
 1.8
 1.3
38 PCED1A PC-esterase domain containing 1A 64773 0 4.2 4.0
 1.5
 3.4
 0.8
-0.5
 4.6
0.9
 1.5
-0.1
 0.6
0.1
 -0.1
-0.5
 0.2
-0.4
 1.5
0.2
 0.7
 0.1
-0.3
 -0.1
39 RRAS RAS related 6237 0 4.2 4.5
 1.9
 2.8
 0.5
 2.4
 0.7
 2.7
 0.1
 0.5
 2.5
 0.9
 -0.0


40 TNFSF12 TNF superfamily member 12 8742 0 4.1 3.4
 1.7
 3.9
 2.0
 1.7
 0.4
 2.3
 1.4
 1.2
 2.8
 1.1
 0.3
1.1
 1.5
41 MFAP2 microfibril associated protein 2 4237 0 4.1 4.0
 1.3
 3.3
 2.2
 2.0
 1.5
 3.3
 1.1
 3.0
 3.2
 2.5
 3.9
 1.3
 1.0
 2.9
42 LAYN layilin 143903 0 4.1 3.4
 2.1
 3.9
 2.3
0.8
 2.5
-0.7
 1.8
0.3
 2.7
-0.3
 1.3
1.0
 1.3
 -1.5
 1.3
 -0.9
 2.3
 2.4
0.4
 1.3
0.7
43 SYDE1 synapse defective Rho GTPase homolog 1 85360 0 4.1 3.3
 1.3
 3.9
 2.4
1.4
 3.2
-1.3
 3.2
-0.2
 4.1
-1.4
 2.9
0.8
 2.6
0.5
 3.0
-0.7
 1.1
0.1
 1.2
-1.2
 0.6
0.1
 1.2
-0.1
 0.9
0.8
44 SPAG4 sperm associated antigen 4 6676 0 4.1 3.9
 2.0
 3.2
 -1.2
 1.4
 -1.1
 2.3
 -0.4
 0.5
 1.3
 0.1
 0.4


45 COL6A2 collagen type VI alpha 2 chain 1292 1 4.1 4.1
 2.6
 3.0
 2.6
 4.6
 2.7
 3.4
 4.8
 3.2
 5.3
 1.0
 2.9
 2.4
 1.2
 1.7
46 C1QTNF6 C1q and TNF related 6 114904 0 4.1 3.6
 1.4
 3.5
 0.3
 2.6
 1.0
 2.7
 0.9
 2.0
 2.2
 0.9
 1.7
 1.6
 2.4
0.7
 1.1
1.0
47 PCBP4 poly(rC) binding protein 4 57060 0 4.1 3.4
 2.1
 3.7
 0.8
0.5
 4.6
-0.7
 0.4
0.1
 1.0
0.4
 1.0
0.3
 1.4
0.5
 1.5
0.5
 1.0
0.9
 0.2
0.1
 0.5
0.4
 0.3
 0.8
0.5
48 NFATC4 nuclear factor of activated T cells 4 4776 0 4.0 4.2
 2.3
 3.0
 1.4
 1.1
 0.8
 3.2
 2.9
 1.8
 2.0
 3.2
 2.1


49 SLC39A13 solute carrier family 39 member 13 91252 0 4.0 4.1
 1.8
 3.0
 0.3
0.1
 3.3
2.9
 1.1
0.3
 2.8
1.9
 1.4
0.4
 0.3
0.2
 3.5
2.5
 1.1
0.8
 0.5
0.0
 1.9
 2.1
-0.4
 2.6
0.3
50 NPR2 natriuretic peptide receptor 2 4882 0 4.0 3.3
 2.8
 3.7
 2.1
1.2
 3.3
1.6
 2.9
1.1
 1.5
0.7
 2.1
1.9
 3.3
0.7
 4.1
0.2
 2.6
0.7
 3.3
-0.8
 1.7
0.6
 1.5
0.2
 1.4
0.7
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