Orthologous genes in OrthoFinder**

Species Gene Description
 rno-u.3   Ttr   transthyretin 
 rno-r.3   Ttr   transthyretin 
 rno-m.5   Ttr   transthyretin 
 mmu-u.4   Ttr   transthyretin 
 hsa-u.4   TTR   transthyretin 
 mcc-u.3   TTR   transthyretin 
 cfa-u.3   TTR   transthyretin 
 gga-u.3   112531842   transthyretin-like 
 gga-u.3   TTR   transthyretin 
 dre-u.3   ttr   transthyretin (prealbumin, amyloidosis type I) 

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Top 50 coexpressed genes to Ttr (rno-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 rno4979   Cholesterol metabolism  6 48 6.49
 rno830   Retinol metabolism  4 65 4.36
 rno3320   PPAR signaling pathway  4 79 4.03
 rno4610   Complement and coagulation cascades  4 81 3.98
 rno140   Steroid hormone biosynthesis  3 65 3.00

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rno:Ttr (transthyretin) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

rno-u.3
for
Ttr
rno-r.3
for
Ttr
rno-m.5
for
Ttr
mmu-u.4
for
Ttr
hsa-u.4
for
TTR
mcc-u.3
for
TTR
cfa-u.3
for
TTR
gga-u.3
for
112531842
gga-u.3
for
TTR
dre-u.3
for
ttr
1 Mfrp membrane frizzled-related protein 315597 7.8 3.5
 3.9






2 Ahsg alpha-2-HS-glycoprotein 25373 6.2 2.8
 3.1
 4.4
 6.5
 3.3
 6.8
 1.3
 4.3
 4.9
3 Otx2 orthodenticle homeobox 2 305858 6.2 2.6
 3.3
 6.0
0.6
 1.8
0.9
 2.5
-0.5
2.5
0.2
 1.4
0.9
 0.3
-0.1
4 Sostdc1 sclerostin domain containing 1 266803 6.0 2.5
 3.3
 5.4
 2.0
 -1.0
-0.7
 -0.3
 -0.5
5 Cltrn collectrin, amino acid transport regulator 57395 5.8 2.0
 3.6
 7.0
 1.9
 0.1
 0.9
 0.3
 1.1
 1.7
6 Slco1a5 solute carrier organic anion transporter family, member 1A5 80900 5.7 2.5
 2.9
 2.6
2.3
0.8
0.8
 4.9
7 Pon1 paraoxonase 1 84024 5.7 3.1
 2.3
 4.7
1.2
 3.5
2.5
 2.5
1.7
 5.6
0.9
 1.8
 2.0
 1.2
1.0
8 Cldn2 claudin 2 300920 5.3 2.6
 2.5
 8.8
 2.3
0.2
 -0.2
 2.0
9 F5 coagulation factor V 304929 5.3 2.4
 2.7
 6.4
 3.0
 2.3
 1.0
 1.0
 1.0
 1.4
10 Rup2 urinary protein 2 619560 4.7 2.0
 2.5






11 Bhmt2 betaine-homocysteine S-methyltransferase 2 365972 4.7 2.2
 2.3
 7.0
5.0
 3.3
1.6
 1.3
 3.8
3.5
 -0.7
 0.7
 0.8
12 Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 84050 4.6 2.4
 1.9
 4.4
0.8
 1.6
1.1
 2.2
0.7
 -0.3
-0.6
 -0.0
-1.0
 1.8
-0.2
 1.9
1.4
13 Prr32 proline rich 32 683753 4.5 2.5







14 LOC299282 Serine protease inhibitor 299282 4.4 2.4
 1.9
 5.2
1.5
 3.1
 2.6
 4.1


15 Alb albumin 24186 4.4 1.8
 2.4
 9.4
 7.3
 3.7
 5.7
 2.0
 5.3
16 Ambp alpha-1-microglobulin/bikunin precursor 25377 4.4 1.6
 2.7
 7.8
 5.7
 4.6
 5.8
 0.6
 3.6
 3.0
17 Apoh apolipoprotein H 287774 4.2 1.4
 2.7
 5.4
 10.0
 3.2
 4.8
 1.6
 5.9
 0.2
18 Folr1 folate receptor alpha 171049 4.2 2.2
 1.9
 6.6
0.7
 1.9
-0.6
 2.8
1.1
 0.6
0.2
 0.5
-1.5
 1.3
0.5
 0.8
19 Tf transferrin 24825 4.2 2.3
3.7
2.4
 5.1
-0.5
 3.4
0.4
 3.7
2.3
 1.3
 5.8
 1.0
20 Clic6 chloride intracellular channel 6 304081 4.1 2.3
9.4
1.0
 0.3
0.1
 1.7
0.4
 0.5
0.3
 0.9
0.1
 2.6
0.6
 1.1
0.4
21 Mdk midkine 81517 4.1 2.1
 1.8
 1.1
 -0.2
 1.6
 -1.4
 0.9
 0.6
 -0.1
-0.4
22 Apoc1 apolipoprotein C1 25292 4.0 2.0
 1.9
 2.2
 1.8
 2.7
 1.2

-0.0
23 LOC102549099 uncharacterized LOC102549099 102549099 4.0 2.2







24 Fabp1 fatty acid binding protein 1 24360 3.9 1.7
 2.0
 7.4
 7.7
 4.5
 1.9
 -0.6
 1.3
25 Gc GC, vitamin D binding protein 24384 3.9 1.7
 2.0
 7.6
 8.0
 2.8
 9.1
 0.6
 5.5
 9.1
26 Apoa2 apolipoprotein A2 25649 3.9 1.4
 2.4
 8.1
 8.6
 2.0
 6.5
 0.6
 2.9
27 LOC103693047 uncharacterized LOC103693047 103693047 3.8 2.1







28 Kl Klotho 83504 3.7 2.2
 1.4
 6.2
 1.0
 1.6
 -0.3
 0.0
 0.2
 2.0
29 Serpina3c serine (or cysteine) proteinase inhibitor, clade A, member 3C 24794 3.7 1.9
 1.6
 5.2
1.5
 3.1
 2.6
 4.1


30 Tmem72 transmembrane protein 72 362424 3.7 1.9
 1.6
 5.7
3.2
-0.4
 0.6
 0.5
31 Pla2g5 phospholipase A2, group V 29354 3.5 1.8
 1.6
 1.8
 2.0
0.3


32 Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 171138 3.5 1.5
 1.9
 8.0


0.2
 -0.5
33 Cfhr1 complement factor H-related 1 289057 3.5 1.9
3.0
2.2
 4.3
2.6
 3.5
1.7
 2.1
0.6
 1.9
 0.4
 3.4
1.8
34 Serpina1 serpin family A member 1 24648 3.4 1.1
 2.2
 9.3
8.0
 3.3
 1.7
 2.9
 1.8
1.7
 5.4
4.9
 4.4
3.9
35 Apoa1 apolipoprotein A1 25081 3.4 1.4
 2.0
 8.6
 5.7
 3.5
 1.5
 0.6
 3.3
 -1.1
36 Slc4a5 solute carrier family 4 member 5 297386 3.4 1.9
5.1
2.7
 1.6
1.6
 1.4
1.4
 1.3
1.3
 2.4
1.8
 1.2
0.8
 1.1
0.7
37 Serpina4 serpin family A member 4 246328 3.4 2.6
 0.7
8.2
 2.6
 5.2


38 Slc13a4 solute carrier family 13 member 4 503568 3.3 1.8
5.3
1.8
 3.4
1.2
 2.1
2.1
 1.9
0.4
 0.9
0.8
 3.4
3.2
 1.4
0.0
39 Ca14 carbonic anhydrase 14 791259 3.3 1.4
 1.7
 2.7
 1.1
 0.5
 -0.1
 -0.1
 0.1
 0.4
40 LOC100912026 urinary protein 3-like 100912026 3.2 1.8







41 Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 266682 3.2 1.7
 1.4
 5.8
4.0
 2.8
2.4
 3.2
2.4
 -0.2
 0.5
0.4
 1.7
1.0
 4.4
2.1
42 Plg plasminogen 85253 3.2 1.3
 1.8
 6.3
 7.1
 3.7
 3.5
 1.1
1.0
 4.8
1.9
 4.2
43 Igf2 insulin-like growth factor 2 24483 3.2 1.6
 1.5
 3.6
2.3
 0.6
 -0.4
 0.9
 1.7
1.5
44 Rdh7 retinol dehydrogenase 7 360420 3.2 1.7
 1.3
 5.8
4.7
 2.6
1.4
 2.5
1.8
 1.8
1.0
 1.2
0.2
 3.3
0.4
 2.5
1.7
45 Apoc3 apolipoprotein C3 24207 3.2 1.1
 2.0
 7.3
 9.1
 5.1
 2.0
 0.8
 4.2
46 Ugt2b15 UDP glucuronosyltransferase family 2 member B15 266685 3.2 1.7
 1.3
 7.3
5.7
 6.8
5.4
 4.0
3.7
 3.2
0.2
 0.6
-0.2
 4.1
0.9
 3.0
2.6
47 Krt18 keratin 18 294853 3.1 1.3
 1.8
 5.4
 0.7
 0.7
 0.6
 1.5
 0.7
 0.4
0.1
48 Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 286953 3.1 1.8
 1.2
 5.5
4.9
 3.8
2.5
 3.1
3.0
 7.4
3.1
 1.4
1.0
 3.7
2.8
 1.3
1.2
49 Apoc2 apolipoprotein C2 292697 3.1 1.2
 1.9

4.0
 4.9
 0.5
 2.1
 0.7
50 Fyb2 FYN binding protein 2 500514 3.1 1.7


0.3
-0.9
 0.8
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