Orthologous genes in OrthoFinder**

Species Gene Description
 mmu-u.4  Shc2  SHC (Src homology 2 domain containing) transforming protein 2 
 mmu-r.6  Shc2  SHC (Src homology 2 domain containing) transforming protein 2 
 mmu-m.5  Shc2  SHC (Src homology 2 domain containing) transforming protein 2 
 mmu-u.4  Shc1  src homology 2 domain-containing transforming protein C1 
 mmu-u.4  Shc3  src homology 2 domain-containing transforming protein C3 
 mmu-u.4  Shc4  SHC (Src homology 2 domain containing) family, member 4 
 rno-u.3  Shc4  SHC adaptor protein 4 
 rno-u.3  Shc3  SHC adaptor protein 3 
 rno-u.3  Shc2  SHC adaptor protein 2 
 hsa-u.4  SHC3  SHC adaptor protein 3 
 hsa-u.4  SHC1  SHC adaptor protein 1 
 hsa-u.4  SHC4  SHC adaptor protein 4 
 mcc-u.3  SHC3  SHC adaptor protein 3 
 mcc-u.3  SHC4  SHC adaptor protein 4 
 mcc-u.3  SHC1  SHC adaptor protein 1 
 cfa-u.3  SHC4  SHC adaptor protein 4 
 cfa-u.3  SHC3  SHC adaptor protein 3 
 cfa-u.3  SHC2  SHC adaptor protein 2 
 gga-u.3  SHC3  SHC adaptor protein 3 
 gga-u.3  SHC2  SHC (Src homology 2 domain containing) transforming protein 2 
 gga-u.3  SHC4  SHC adaptor protein 4 
 dre-u.3  shc3  SHC (Src homology 2 domain containing) transforming protein 3 
 dre-u.3  shc2  SHC (Src homology 2 domain containing) transforming protein 2 
 dre-u.3  shc1  SHC (Src homology 2 domain containing) transforming protein 1 
 dme-u.3  Shc  SHC-adaptor protein 
 cel-u.3  shc-1  SHC-transforming protein homolog 1 

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Top 50 coexpressed genes to Shc2 (mmu-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 mmu4724   Glutamatergic synapse  3 103 2.46
 mmu4022   cGMP-PKG signaling pathway  3 173 -
 mmu4360   Axon guidance  2 181 -
 mmu4020   Calcium signaling pathway  2 240 -
 mmu4080   Neuroactive ligand-receptor interaction  2 376 -

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mmu:Shc2 (SHC (Src homology 2 domain containing) transforming protein 2) External Links;


Show/Hide Columns:          
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID
Other ID CoexPub LINK Target Reference

mmu-u.4
for
Shc2


mmu-r.6
for
Shc2


mmu-m.5
for
Shc2


mmu-u.4
for
Shc1


mmu-u.4
for
Shc3


mmu-u.4
for
Shc4


rno-u.3
for
Shc4


rno-u.3
for
Shc3


rno-u.3
for
Shc2


hsa-u.4
for
SHC3


hsa-u.4
for
SHC1


hsa-u.4
for
SHC4


mcc-u.3
for
SHC3


mcc-u.3
for
SHC4


mcc-u.3
for
SHC1


cfa-u.3
for
SHC4


cfa-u.3
for
SHC3


cfa-u.3
for
SHC2


gga-u.3
for
SHC3


gga-u.3
for
SHC2


gga-u.3
for
SHC4


dre-u.3
for
shc3


dre-u.3
for
shc2


dre-u.3
for
shc1


dme-u.3
for
Shc


cel-u.3
for
shc-1

1 C2cd4c C2 calcium-dependent domain containing 4C 237397 0 8.9 11.1
2.6
-0.2
0.3
1.2
-0.3
1.0
3.6
-0.5
-0.8
-1.1






0.2
-0.6
1.1
0.4
0.3
-1.3
1.3
0.0
0.7
0.2
0.1
-0.1


2 Gprin1 G protein-regulated inducer of neurite outgrowth 1 26913 0 7.0 3.6
5.0
-1.1
3.1
-0.5
-0.4
0.7
3.5
0.7
0.6
-0.5
2.4
-0.4
-0.3
0.6
0.9
-0.3
-0.0
1.4
0.3
1.0
-1.6
-0.3


3 Lrp3 low density lipoprotein receptor-related protein 3 435965 0 7.0 5.6
3.8
0.1
1.5
-1.1
-0.3
-0.6
1.0
1.8
-0.8
-0.8
0.9
-1.1
-0.8
0.3
1.0
0.8
0.6
-1.7
-0.1
-0.8
2.3
-1.1


4 B4galt2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 53418 0 6.6 3.9
4.4
2.2
0.5
3.0
-1.6
1.1
-0.8
0.6
-0.6
2.1
0.4
5.6
0.4
-0.1
-2.5
2.0
0.7
0.5
-1.2
-0.0
-0.2
1.5
-0.9
3.6
0.1
-1.2
-2.1
0.2
-0.8
-0.2
-0.8
0.7
-0.2
0.7
-0.7
-0.5
-1.8
-0.1
-0.5
2.2
0.9
0.7
-0.3
1.6

5 Gpr27 G protein-coupled receptor 27 14761 0 6.0 4.0
3.7
-0.1
1.8
0.1
0.2
1.6
3.2
-0.6
-1.5
-0.0
-0.5
-0.6
-1.3











6 Insyn1 inhibitory synaptic factor 1 319477 0 5.8 4.3
3.3
0.4
1.7
0.2
0.5
1.8
3.0
2.0
-1.1
-0.1
-0.3
-0.1
-0.9
-1.1
0.3
2.2
0.4
1.3
0.1
2.5
0.8
-1.4


7 Dact3 dishevelled-binding antagonist of beta-catenin 3 629378 0 5.6 2.3
4.4
1.2
3.4
0.2
0.0
2.8
4.4
0.2
-1.4
1.2
1.0
-0.4
0.1
0.7
1.5
0.1



-0.4
-1.1
1.1
-1.3
0.3
-1.3


8 Diras1 DIRAS family, GTP-binding RAS-like 1 208666 0 5.4 2.4
4.1
0.4
-2.0
3.1
2.1
0.8
0.8
1.1
-1.1
2.4
1.1
2.7
-0.6
1.6
1.4
-0.1
-1.0
1.7
0.4
1.3
1.2
1.2
1.1
0.1
-0.4
-0.0
-0.6
0.7
0.5
0.5
-0.1
1.5
1.3
1.8
-0.9
0.9
0.9
1.1
-0.2
-0.4
-0.3
-0.2
9 Numbl numb-like 18223 0 5.4 4.2
3.1
2.3
1.7
0.5
0.0
0.3
-0.8
0.7
-1.0
1.2
0.4
5.0
-1.1
-0.0
-0.1
2.3
0.9
-0.2
-0.7
0.7
-0.5
0.8
-0.4
1.1
-0.1
0.8
0.2
-0.5
-0.5
-1.0
-1.0
-1.3
1.7
-0.8
1.0
-0.6
0.7
0.5
0.8
-0.1
0.2
2.8
10 Dpysl4 dihydropyrimidinase-like 4 26757 0 5.0 4.3
2.6
-0.3
-0.5
2.6
2.1
0.8
0.4
0.7
0.6
1.5
0.9
3.8
3.2
2.4
1.9
0.6
0.1
2.0
0.9
1.2
1.2
1.5
0.8
1.3
0.2
0.8
0.6
1.2
0.4
1.8
0.4
0.4
0.3
1.2
1.0
0.1
-0.2
2.7
2.3
0.6
0.5
1.3
1.3
-0.9
3.4
-0.2
11 Smpd3 sphingomyelin phosphodiesterase 3, neutral 58994 0 4.9 4.2
2.6
-1.6
1.2
-1.3
-1.0
0.2
2.3
-0.1
-0.2
-0.9
2.0
-0.3
-0.4
-0.1
2.0
0.6
1.1
-1.8
0.8
0.7
0.2
-1.2


12 Lrfn3 leucine rich repeat and fibronectin type III domain containing 3 233067 0 4.8 4.4
2.4
0.6
0.3
2.7
2.6
1.0
0.6
-0.2
-0.4
1.6
1.1
2.6
1.9
2.9
0.2
-0.2
-0.5
0.9
0.7
1.3
0.9
0.4
0.4
0.8
0.4
2.0
0.2
0.6
0.6
0.4
0.4
1.1
0.7
0.8
0.6
0.4
-0.0
2.8
2.3
0.5
0.1
1.0
0.8

-1.5
13 Meis3 Meis homeobox 3 17537 0 4.8 4.1
2.5
0.9
-0.1
2.0
0.6
-0.1
-0.1
0.3
-0.3
3.4
0.5
3.9
1.8
1.2
0.7
0.3
-0.2
1.6
1.5
1.1
0.5
2.1
0.5
1.0
1.0
0.9
0.1
0.9
-0.9
0.2
0.0
0.7
-0.5
1.8
0.3
0.4
-1.0
0.8
0.4
0.9
0.3
3.9
3.2
-1.1
2.9
14 Sobp sine oculis binding protein 109205 0 4.7 3.8
2.6
-0.5
3.7
0.3
0.0
1.6
2.1
1.3
-1.1
0.8
-0.1
0.0
-0.4
-0.1
0.3
0.2
-0.0
1.0
1.0
-0.5
-2.1
0.6
-1.0
-0.6
-1.3
0.6

15 Dok5 docking protein 5 76829 0 4.7 3.0
3.1
0.7
-0.4
3.6
2.7
1.7
1.1
1.0
0.1
4.3
0.8
1.0
0.2
0.8
-0.9
0.3
1.7
0.3
0.6
0.1
0.6
-0.9
1.2
1.1
-0.4
1.2
-0.3
0.1
-0.2
0.7
-0.3
0.9
0.3
-1.4


16 Ajm1 apical junction component 1 381353 0 4.6 0.5
4.4
-0.1
0.8
1.2
-1.0
1.3
3.3
-0.2
0.1
-0.6
0.5
-0.3
1.5
0.5
1.8
-0.1
0.6
2.8
-0.2
3.7
1.8
1.1
-0.5
-1.3
-1.7
0.6
1.0
17 Sema6c sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 20360 0 4.6 2.1
3.4
0.2
-0.0
1.2
-0.5
0.7
-0.4
0.9
0.1
0.7
-1.1
2.6
-0.8
0.1
-0.1
1.0
-0.6
2.3
-0.8
0.6
-0.8
-0.0
-0.6
1.3
-2.0
1.5
1.1
2.7
0.3
1.5
0.2
0.1
-0.2
1.2
-0.4
0.3
-2.3
0.0
-0.7
0.6
-0.6
0.8
-0.1
0.6
-0.9

18 Kif1a kinesin family member 1A 16560 0 4.6 3.3
2.8
0.7
-0.3
3.6
0.2
2.0
0.4
2.1
1.4
2.6
0.2
2.2
0.5
1.0
0.3
2.2
-0.6
0.6
0.5
1.0
-0.8
0.7
-0.3
1.4
-0.1
0.6
-0.1
1.1
0.9
0.6
0.3
0.9
-0.2
1.4
-1.3
0.1
-0.7
2.1
1.9
1.1
0.8
1.3
0.6
0.4
-0.6
19 Slc8a2 solute carrier family 8 (sodium/calcium exchanger), member 2 110891 0 4.5 1.7
3.6
-0.7
-1.5
2.7
0.6
0.1
0.1
0.7
-0.4
2.7
1.9
1.1
1.0
0.1
-0.2
-0.4
-1.6
0.6
-1.5
1.2
-0.2
0.6
-0.2
1.4
-0.3
0.3
0.3
1.4
0.6
0.8
0.7
0.6
0.1
2.1
0.5
1.8
0.3
1.2
0.6
0.9
0.5
-0.1
-0.2
-0.0
1.7
0.4
20 Dbn1 drebrin 1 56320 0 4.5 4.1
2.2
0.4
1.3
0.3
0.5
-0.0
3.7
0.9
0.8
0.4
1.0
-1.5
-0.0
-0.7
-0.4
0.2
-0.2
1.9
0.6
0.2
-0.8
0.2


21 LOC432842 uncharacterized LOC432842 432842 0 4.4 1.4
3.7























22 Gdap1l1 ganglioside-induced differentiation-associated protein 1-like 1 228858 0 4.4 3.7
2.4
-0.9
-1.3
1.6
0.7
1.9
0.9
0.2
-0.4
1.1
-0.3
1.8
1.2
1.7
-1.0
0.2
0.5
0.2
1.4
1.0
0.3
-0.5



0.7
0.2
1.5
0.7
0.1
-0.9
0.4
-0.6
0.8
-0.7
0.7
-0.4
-0.1

23 Zfp13 zinc finger protein 13 22654 0 4.4 2.7
2.9
0.4
1.2
-0.2



1.0
0.8
0.1
-0.4
-1.1
0.5
-0.5
-0.0
1.7








24 Dact2 dishevelled-binding antagonist of beta-catenin 2 240025 0 4.4 2.4
3.1
0.3
0.7
-1.4
-0.4
0.1
1.9



-0.1
0.2
-1.4
-0.4
0.4
0.4
-0.4
-0.6
-0.4
-0.5
-1.5
0.9


25 Shank1 SH3 and multiple ankyrin repeat domains 1 243961 0 4.4 0.7
4.0
-0.2
2.6
-0.6
-0.3
4.2
0.7
1.7
0.0
1.0
1.4
0.1
-0.2
1.3
1.7
0.3



1.7
0.4
0.5


26 Adra2c adrenergic receptor, alpha 2c 11553 0 4.3 2.0
3.3
-1.1
2.8
-0.2



0.3
0.3
-1.2
0.6
0.2
-0.3



-0.8
-0.3
0.5
0.5
-0.0
-0.1


27 Ccdc92b coiled-coil domain containing 92B 432582 0 4.3 2.1
3.2
0.2
1.6
-0.2
-0.6
-0.2
2.7



-0.5
-1.0
-0.6



0.1
-0.5
0.7
0.8
0.2
1.1


28 Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 16520 0 4.3 2.4
3.0
0.5
2.7
-0.4
0.3
1.6
2.9
0.7
-1.1
-0.0
2.1
0.2
-0.2
0.1
1.0
0.2
0.9
0.9
1.4





29 Lmtk3 lemur tyrosine kinase 3 381983 0 4.3 1.7
3.4
-0.6
0.8
-0.7
0.4
1.3
2.8
0.2
-0.8
-1.3
1.6
-0.5
-1.0
-0.2
1.1
-0.3








30 Lhfpl4 lipoma HMGIC fusion partner-like protein 4 269788 0 4.3 3.1
2.6
0.2
-0.4
3.4
2.1
2.4
0.9
2.1
0.6
3.1
1.4
2.4
-0.5
1.7
-1.5
1.5
0.9
0.9
2.4
-1.1
-0.2
-0.7
1.8
0.6
1.1
-0.6
0.2
0.1
-0.0
-0.4
2.1
0.8
0.8
0.1
2.4
1.6
0.7
-0.8
1.0
0.2
0.5
-0.9
31 Dlg4 discs large MAGUK scaffold protein 4 13385 0 4.3 3.2
2.5
1.2
0.4
2.8
2.2
2.2
0.8
1.1
1.0
3.0
2.9
4.4
0.6
2.4
1.1
2.6
1.1
1.0
0.1
1.0
-0.4
0.9
0.5
1.0
0.7
1.1
0.3
2.1
0.5
2.0
-0.1
1.6
0.6
0.5
0.2
1.2
-0.1
3.2
1.9
1.3
1.2
1.4
-0.5

0.7
32 Asphd2 aspartate beta-hydroxylase domain containing 2 72898 0 4.3 4.5
1.8
0.1
2.5
1.0
0.5
1.3
1.9
-0.5
-0.6
-0.5
-0.6
-1.4
1.6
0.3
1.7
1.5
-0.4
1.7
-1.2
1.4
1.3
0.7
-0.3
2.3
-0.2


33 Nfatc4 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 73181 0 4.2 3.4
2.3
2.0
-0.2
-0.5
0.3
2.4
1.9
1.2
1.5
0.1
-0.2
0.7
1.3
-0.3
-1.3
-1.6








34 Sh3rf3 SH3 domain containing ring finger 3 237353 0 4.2 3.2
2.5
0.0
-0.5
4.8
0.5
1.2
-0.3
0.6
0.9
-0.4
2.6
0.7
0.9
-1.2
0.6
0.1
0.6
-0.0
1.9
0.4
1.4
-1.7
1.4
1.4
0.1
-0.0
-0.3
-0.7
1.0
-1.4
2.0
-1.0
0.7
-0.2
0.2
-0.2
2.5
2.2

35 Lingo1 leucine rich repeat and Ig domain containing 1 235402 0 4.2 3.2
2.4
-0.6
3.3
0.9



-0.0
-0.7
0.5
1.0
0.5
-1.3



-0.6
2.1
1.2
1.2
0.6
-0.0


36 Rnf165 ring finger protein 165 225743 0 4.2 3.3
2.4
0.4
-1.6
3.4
-0.4
-0.9
-1.7
0.3
-0.2
1.4
-0.6
1.1
-0.2
-0.3
0.8
0.1
1.7
-0.1
0.6
0.1
-0.3
-0.8
-1.1
-0.1
-0.7
0.5
-1.2
1.5
-0.3
1.1
0.0
0.5
0.2
1.5
-0.5
-0.2
-0.7
1.2
-0.0
2.5
37 Hhipl1 hedgehog interacting protein-like 1 214305 0 4.1 4.0
1.9
-0.1
2.2
0.6
0.6
3.5
2.5



0.4
-0.1
1.3
0.1
0.4
-0.9
1.2
0.9
-0.0
-0.1
1.6
1.5
0.3
0.2
-0.2
-0.5
-0.3
-0.3


38 Lrfn2 leucine rich repeat and fibronectin type III domain containing 2 70530 0 4.1 2.2
2.9
0.6
0.3
2.7
2.6
1.0
0.6
-0.2
-0.4
1.6
1.1
2.6
1.9
2.9
0.2
-0.2
-0.5
0.9
0.7
1.3
0.9
0.4
0.4
0.8
0.4
2.0
0.2
0.6
0.6
0.4
0.4
1.1
0.7
0.8
0.6
0.4
-0.0
2.8
2.3
0.5
0.1
1.0
0.8

-1.5
39 Ajap1 adherens junction associated protein 1 230959 0 4.1 2.1
2.9
-1.0
3.0
0.7
-0.0
1.0
2.0
1.2
0.2
-0.1
-0.3
-0.4
-0.2
0.5
-0.5
0.3
-1.5
1.9
-1.4
-0.2
-0.1
-1.1


40 Sult4a1 sulfotransferase family 4A, member 1 29859 0 4.0 2.3
2.8
1.1
2.2
0.2
0.6
2.1
1.0



0.4
0.1
-1.3
-0.6
0.9
1.2
0.0
2.6
1.3
-0.2
0.8
-0.9


41 Dnm1 dynamin 1 13429 0 4.0 4.9
1.3
3.5
-0.2
1.8
0.9
1.0
0.6
-0.6
-1.0
2.0
-0.2
1.9
-0.2
2.9
2.2
0.5
-0.1
1.7
-0.5
1.6
-0.2
0.8
-0.5
1.0
-0.1
0.1
-1.0
1.5
0.1
1.0
0.1
0.4
0.0
1.1
-0.5
0.4
-0.8
2.7
1.4
0.3
0.2
0.8
0.6
-0.5
6.1
42 Cntnap1 contactin associated protein-like 1 53321 0 4.0 1.5
3.3
0.6
-0.6
3.1
2.3
1.7
1.0
1.5
0.5
1.4
1.0
2.3
1.3
2.4
1.4
2.1
0.6
2.5
1.1
1.3
1.0
1.5
0.6
0.5
-0.3
1.7
1.2
1.9
1.0
0.8
0.5
1.5
1.4
1.3
0.9
0.4
0.3
2.7
2.6
1.2
1.0
0.8
0.7
1.2
-0.5
1.9
0.5
43 Lmx1b LIM homeobox transcription factor 1 beta 16917 0 4.0 1.8
3.1
0.1
2.0
0.3
0.3
-0.6
-0.6
-0.3
-0.2
0.3



1.7
0.6
-0.8
0.2
-0.2
1.0
0.7
-0.3
-0.4
0.4
-0.1
1.1
0.2
1.0
0.7
-0.0
-0.2
-0.1
44 Prrt3 proline-rich transmembrane protein 3 210673 0 4.0 1.4
3.3
0.1
1.4
0.2
-0.7
0.6
2.4
-0.2
-0.1
0.7
0.7
-0.5
-2.3
1.2
1.2
-0.5
0.6
3.1
-0.3
0.1
-1.5
1.5


45 Ap3b2 adaptor-related protein complex 3, beta 2 subunit 11775 0 3.9 3.3
2.1
1.7
-0.5
1.3
-0.5
0.7
-0.8
1.1
-0.7
0.6
-0.9
2.7
0.6
-1.1
2.2
-0.8
1.0
0.1
-0.1
-0.5
1.0
0.5
1.3
-0.0
0.9
-0.0
1.0
-1.5
0.5
-1.0
1.9
-0.0
-0.0
-1.1
0.7
-0.2
0.6
0.3
-0.4
-0.8
-1.9
-1.3
46 Cabp7 calcium binding protein 7 192650 0 3.9 0.5
3.7
-0.4
0.3
-0.7
-0.1
1.0
0.4



1.3
-1.4
-0.8
0.0
0.1
0.1
-0.1
2.0
0.3
2.5
1.2
-0.3
-1.4
-0.9
-1.6


47 Cabp1 calcium binding protein 1 29867 0 3.9 2.4
2.6
0.4
2.2
0.4
-0.9
1.1
1.1
1.2
-0.4
-0.2
1.7
0.8
-1.5
-0.7
0.9
3.2
0.8
0.6
-0.5





48 Brsk1 BR serine/threonine kinase 1 381979 0 3.8 3.6
1.8
-0.6
-1.4
3.0
2.1
0.8
0.6
1.2
0.2
1.8
1.1
2.5
0.1
2.2
0.2
0.4
-0.8
1.5
0.3
1.8
0.6
1.0
0.6
1.0
-0.9
0.3
-0.4
1.5
1.4
2.2
-0.5
2.1
0.4
1.7
1.2
1.0
1.6
0.8
-0.2
-0.4
-1.1
-1.0
49 Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 14810 0 3.8 1.4
3.1
-0.4
1.9
-0.2
-0.8
2.0
1.9
1.1
-1.3
-0.3
2.3
0.2
-2.0
0.6
0.3
0.2
0.8
0.4
0.6
2.0
0.9
-0.2
-0.2
-1.2
-1.4
-0.2
1.3
50 Tmem200c transmembrane protein 200C 622645 0 3.8 2.3
2.6
0.4
2.2
-0.2
0.2
1.7
2.0
1.9
-1.1
0.9
0.9
1.8
0.6
0.2
-0.9
0.5
-0.5
1.6
-0.8
1.0
-0.3
0.4
-0.7
0.1
0.0


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