Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-m.7   RYR2   ryanodine receptor 2 
 hsa-u.4   RYR2   ryanodine receptor 2 
 hsa-r.6   RYR2   ryanodine receptor 2 
 hsa-m2.4   RYR2   ryanodine receptor 2 
 hsa-u.4   RYR3   ryanodine receptor 3 
 hsa-u.4   RYR1   ryanodine receptor 1 
 mcc-u.3   RYR3   ryanodine receptor 3 
 mcc-u.3   RYR1   ryanodine receptor 1 
 mcc-u.3   RYR2   ryanodine receptor 2 
 mmu-u.4   Ryr3   ryanodine receptor 3 
 mmu-u.4   Ryr2   ryanodine receptor 2, cardiac 
 mmu-u.4   Ryr1   ryanodine receptor 1, skeletal muscle 
 rno-u.3   Ryr2   ryanodine receptor 2 
 rno-u.3   Ryr3   ryanodine receptor 3 
 rno-u.3   Ryr1   ryanodine receptor 1 
 cfa-u.3   RYR3   ryanodine receptor 3 
 cfa-u.3   RYR1   ryanodine receptor 1 
 cfa-u.3   RYR2   ryanodine receptor 2 
 gga-u.3   101748756   ryanodine receptor 1-like 
 gga-u.3   RYR2   ryanodine receptor 2 
 gga-u.3   RYR3   ryanodine receptor 3 
 dre-u.3   ryr2a   ryanodine receptor 2a (cardiac) 
 dre-u.3   ryr1a   ryanodine receptor 1a (skeletal) 
 dme-u.3   RyR   Ryanodine receptor 
 cel-u.3   unc-68   Uncharacterized protein 

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Top 50 coexpressed genes to RYR2 (hsa-m.7 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa4080   Neuroactive ligand-receptor interaction  5 189 3.60
 hsa5033   Nicotine addiction  4 28 5.85
 hsa4727   GABAergic synapse  4 75 4.13
 hsa5032   Morphine addiction  4 76 4.10
 hsa4723   Retrograde endocannabinoid signaling  4 125 3.27

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hsa:RYR2 (ryanodine receptor 2) External Links;


Show/Hide Columns:          
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-m.7
for
RYR2
hsa-u.4
for
RYR2
hsa-r.6
for
RYR2
hsa-m2.4
for
RYR2
hsa-u.4
for
RYR3
hsa-u.4
for
RYR1
mcc-u.3
for
RYR3
mcc-u.3
for
RYR1
mcc-u.3
for
RYR2
mmu-u.4
for
Ryr3
mmu-u.4
for
Ryr2
mmu-u.4
for
Ryr1
rno-u.3
for
Ryr2
rno-u.3
for
Ryr3
rno-u.3
for
Ryr1
cfa-u.3
for
RYR3
cfa-u.3
for
RYR1
cfa-u.3
for
RYR2
gga-u.3
for
101748756
gga-u.3
for
RYR2
gga-u.3
for
RYR3
dre-u.3
for
ryr2a
dre-u.3
for
ryr1a
dme-u.3
for
RyR
cel-u.3
for
unc-68
1 LINC00889 long intergenic non-protein coding RNA 889 158696 0 3.3

0.9




















2 ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 56899 0 3.2 2.3
 2.0
 2.1
 2.5
0.5
 0.9
0.4
 2.2
0.2
 -0.1
-1.5
 1.4
1.1
 2.2
-1.3
 2.2
0.0
 1.0
-1.7
 2.3
0.1
 1.7
0.5
 -1.0
-1.6
 -1.2
 2.0
 -1.0
 2.2
-1.0
 2.5
0.6
 1.9
0.1
 1.3
1.1
 0.8
0.1
 1.7
3 MGAT4C MGAT4 family member C 25834 0 3.2

3.9

1.8
 -0.3
 1.5
 2.6
 1.6
 -1.1
 0.6
 -1.0
 0.0
 0.2
 -0.2
 0.5
 -0.2
 0.9
 -0.5
 -0.3
 0.1

4 DLG2 discs large MAGUK scaffold protein 2 1740 0 3.0

4.9
 0.1
-0.4
 1.6
-0.1
 0.8
0.7
 0.6
-0.1
 5.0
1.2
 3.8
0.5
 1.5
0.6
 1.1
0.3
 1.9
0.9
 1.0
0.4
 0.4
0.4
 0.7
0.5
 0.4
0.3
 1.8
1.0
 -0.2
-0.4
 1.9
0.4
 1.1
1.1
 4.6
1.1
 2.0
1.7
2.8
5 GRIN2A glutamate ionotropic receptor NMDA type subunit 2A 2903 0 2.9 4.8
 3.6
 4.8
 3.7
3.3
 2.6
1.7
 2.0
1.7
 1.6
0.9
 1.7
0.5
 4.4
3.5
 4.2
3.1
 1.2
0.9
 4.3
3.6
 2.0
0.9
 2.1
0.4
 0.7
-0.6
 1.5
0.5
 1.1
-0.9
 1.5
1.5
 1.9
-0.5
 1.1
-0.2
 3.3
3.1
 2.4
1.9
 1.1
 0.0
6 TCERG1L transcription elongation regulator 1 like 256536 0 2.9 1.3
 1.7
 0.5
 0.4
 1.3


2.1
 1.0
 0.2
 0.6
 -2.1
 0.4


-0.2
 0.1
 -0.7
 0.1
 0.4

7 LRRC7 leucine rich repeat containing 7 57554 0 2.8

3.2







4.0
 1.8
 -0.2


-0.9
 0.8
 0.6
 2.6
 0.3

8 GABRA2 gamma-aminobutyric acid type A receptor subunit alpha2 2555 0 2.7

2.7
 1.6
1.5
 1.4
1.2
 1.4
1.0
 0.8
0.7
 0.8
0.7
 3.1
2.3
 3.4
2.5
 1.3
0.4
 3.5
2.8
 2.5
0.7
 0.5
0.0
 0.8
0.3
 0.9
0.4
 2.2
0.6
 0.6
0.5
 1.6
1.3
 1.3
1.2
 2.0
2.0
 1.2
1.1
 0.5
9 GABRG2 gamma-aminobutyric acid type A receptor subunit gamma2 2566 0 2.7 3.7
 2.9
 3.6
 2.9
1.9
 1.8
1.2
 1.0
1.0
 1.2
0.8
 1.5
1.0
 3.3
1.7
 3.2
2.0
 0.2
0.1
 1.7
0.3
 0.2
-0.3
 0.1
-0.7
 -0.0
-0.6
 -0.1
-0.3
 0.9
0.6
 1.2
0.1
 2.7
1.6
 1.6
1.6
 1.8
0.6
 0.1
0.1
0.4
10 PTCHD1 patched domain containing 1 139411 0 2.7 3.8
 3.3
 3.3
 4.2
 2.3
 -0.2
 1.4
 2.2
 1.4
 1.8
 1.2
 1.8
 -0.1
 -0.0


-0.2
 1.8
 -0.0
 0.9
 -0.4

11 ACTN2 actinin alpha 2 88 0 2.7 4.9
 5.0
 3.5
 3.2
0.7
 7.0
4.7
 1.0
0.0
 4.1
1.3
 2.1
0.4
 3.1
0.3
 2.4
-0.1
 7.2
6.8
 2.0
-0.5
 2.8
1.9
 7.8
4.3
 0.5
0.1
 2.3
2.2
 2.1
1.0
 1.6
1.3
 2.4
0.1
 4.1
-1.1
 1.6
1.5
 6.2
4.9
 4.1
 4.8
12 NKAIN2 sodium/potassium transporting ATPase interacting 2 154215 0 2.7 1.0
 -0.0
 1.7
 3.3
1.7
 2.1
2.0
 1.5
0.5
 0.1
-0.1
 0.1
-0.1
 3.9
0.4
 1.7
0.2
 1.4
0.7
 2.8
0.2
 0.4
-0.1
 0.2
0.1
 1.8
0.2
 0.2
-0.5
 2.9
-0.2
 1.4
-0.8
 0.6
0.4
 -0.2
-0.5
 2.1
0.0
 0.6
0.1
 -0.2
 -0.5
13 HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 348980 0 2.7 4.4
 4.1
 3.5
 2.0
 3.2
 1.0
 0.9
 1.2
 1.2
 4.3
 -0.3
 1.5
 0.3
 -1.0


0.4
 0.3
 -0.3
 2.4
 -0.0

14 PEX5L peroxisomal biogenesis factor 5 like 51555 0 2.7 2.4
 1.5
 2.6
 1.7
-1.2
 1.1
0.8
 0.8
-0.9
 0.1
-1.6
 1.0
0.2
 1.7
-0.6
 1.5
-0.5
 -0.3
-1.1
 3.9
-0.3
 1.3
-0.8
 0.5
0.3
 0.1
 0.1
 -0.7
 0.8
0.2
 1.3
-0.4
 1.6
0.0
 0.8
0.2
 0.2
-0.3
 0.0
 -0.5
15 UNC13C unc-13 homolog C 440279 0 2.7 3.2
 1.9
 3.7
 3.3
0.9
 1.8
1.0
 1.1
0.6
 1.8
0.5
 3.5
0.1
 3.2
1.3
 2.2
1.2
 1.3
0.2
 1.7
1.1
 2.0
1.5
 1.6
1.0
 1.0
-0.7
 0.1
-0.2
 -0.3
-0.6
 1.4
1.0
 1.4
1.3
 0.5
0.5
 4.1
1.9
 0.9
0.7
 1.0
 6.3
16 RBFOX3 RNA binding fox-1 homolog 3 146713 0 2.6 1.9
 1.8
 1.5
 4.7
2.3
 4.6
2.7
 2.1
0.8
 1.2
1.1
 3.9
1.9
 2.5
0.9
 3.0
2.2
 5.1
1.3
 4.3
2.9
 1.9
0.5
 3.6
1.1
 2.0
-1.0
 1.2
-0.5
 2.1
0.5
 2.9
2.0
 1.2
1.0
 0.6
0.0
 2.4
1.8
 1.7
-0.5
 2.1
 0.8
0.2
17 TNNI3K TNNI3 interacting kinase 51086 0 2.6

0.8




0.4
 4.4
 -1.8
 3.4
 -0.1
 -1.4


-0.8
 1.5
 0.7
 -0.1
 4.5
1.6
18 CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 783 0 2.6 4.2
 2.3
 5.1
 2.0
0.4
 2.4
0.3
 1.3
1.2
 1.1
0.7
 2.8
2.3
 3.0
2.2
 4.1
3.0
 3.9
0.6
 1.6
0.3
 3.7
1.7
 4.6
0.5
 1.0
0.4
 1.7
0.5
 1.4
1.4
 4.8
2.3
 4.4
2.2
 1.2
1.1
 2.2
1.7
 2.3
0.2
 4.6
 2.7
19 NRXN1 neurexin 1 9378 0 2.6

1.9
 1.4
 3.5
 0.9
0.4
 0.6
-0.6
 1.9
0.3
 2.0
0.6
 2.8
1.7
 1.1
0.4
 2.2
1.5
 1.0
-0.5
 1.2
0.5


0.6
 0.6
 0.5
 3.6
3.5
 1.3
0.8
 4.8
20 SYN2 synapsin II 6854 0 2.6 2.6
 1.6
 3.0
 2.4
1.2
 2.5
1.6
 1.4
0.3
 2.0
-0.1
 1.6
0.4
 1.7
1.7
 2.7
1.6
 0.7
-0.8
 1.4
0.7
 -0.2
-0.6
 0.9
0.7
 -0.8
-1.1
 2.1
0.7
 0.8
-0.2
 0.1
-0.3
 2.3
0.8
 1.3
1.1
 4.0
3.6
 1.2
0.3
 1.3
 1.1
21 TAFA4 TAFA chemokine like family member 4 151647 0 2.6 2.5
 2.0
 2.5
 2.1
1.0
 1.7
-1.2
 -0.1
-1.0
 0.4
 1.3
0.9
 1.0
-0.6
 1.0
0.1
 0.8
-0.7
 -0.1
-0.4
 1.8
1.7
 0.7
0.4


-0.6
-1.3
 1.6
1.0
 -0.2
-0.2
 0.8
0.4
 0.3
-0.4

22 CHRM3 cholinergic receptor muscarinic 3 1131 0 2.6

4.2
 0.9
 0.8
 1.0
0.8
 0.2
-1.9
 1.5
0.9
 1.4
0.8
 1.6
0.7
 0.2
-0.8
 2.2
0.7
 -0.1
-0.3
 -0.4
-0.5
 -0.2
 1.2
 0.2
 -1.3
 0.0
 0.5
 0.3
 -0.2
 1.8
 2.1
23 LRRTM4 leucine rich repeat transmembrane neuronal 4 80059 0 2.5

4.4

2.3
 0.2
 0.1
 3.3
 2.9
 0.4
 1.5
 -0.1
 0.4


0.7
 0.0
 1.6
 -0.6
 -0.2

24 STXBP5L syntaxin binding protein 5L 9515 0 2.5

4.2
 0.3
 -0.3
 0.6
-0.2
 0.7
-0.4
 0.5
0.1
 2.0
0.7
 4.4
1.7
 -0.3
-1.1
 2.5
1.5
 1.5
-0.2
 1.0
0.9
 2.5
0.9
 0.7
-0.7
 1.4
0.7
 2.0
1.0
 1.8
1.2
 1.8
0.9
 3.9
2.7
 1.1
0.7
 1.8
 2.8
25 RERGL RERG like 79785 0 2.5

3.6

-0.2
 1.2
 1.3





0.5
 0.8
 2.4
 -0.0
 1.1
 0.1
 -0.8
 -0.4
 2.8
 -0.0
26 SERTM1 serine rich and transmembrane domain containing 1 400120 0 2.5 3.2
 2.5
 3.1
 1.6
 1.5


1.3
 1.8
 -0.4
 1.0
 1.2
 -0.8


-0.2
 -0.8
 -1.0



27 LINGO2 leucine rich repeat and Ig domain containing 2 158038 0 2.5 3.2
 1.7
 4.0
 2.0
 -0.2
 1.7
 -0.0
 1.6
 1.9
 1.5
 -0.8





0.4
 0.6
 0.5
 2.3
1.0
 0.1
-0.9

28 SH3GL2 SH3 domain containing GRB2 like 2, endophilin A1 6456 0 2.5 2.5
 1.8
 2.7
 0.9
0.8
 0.6
0.1
 0.2
-0.2
 1.8
1.0
 2.8
0.2
 3.5
0.2
 3.2
0.0
 1.2
-0.8
 0.8
0.5
 0.1
-0.1
 1.0
0.4
 1.5
1.0
 -0.3
-0.6
 1.1
1.1
 0.0
-0.1
 1.9
0.6
 0.4
0.4
 3.7
1.8
 0.9
0.7
 0.8
 -0.6
29 RBFOX1 RNA binding fox-1 homolog 1 54715 0 2.4 3.5
 3.5
 2.6
 4.7
2.3
 4.6
2.7
 2.1
0.8
 1.2
1.1
 3.9
1.9
 2.5
0.9
 3.0
2.2
 5.1
1.3
 4.3
2.9
 1.9
0.5
 3.6
1.1
 2.0
-1.0
 1.2
-0.5
 2.1
0.5
 2.9
2.0
 1.2
1.0
 0.6
0.0
 2.4
1.8
 1.7
-0.5
 2.1
 0.8
0.2
30 RIT2 Ras like without CAAX 2 6014 0 2.4

0.8
 -0.3
 -1.1
 2.0
-0.2
 -0.1
-0.9
 0.6
-1.3
 2.1
0.3
 1.9
-0.4
 -1.1
-1.3
 1.1
0.2
 -0.6
-0.9
 -0.0
-0.2
 0.1
 -1.2
 0.4
 0.5
-0.7
 0.7
0.2
 -0.4
-2.0
 -1.0
 -0.2
 -0.0
31 MTUS2 microtubule associated scaffold protein 2 23281 0 2.4

3.7

0.0
 0.6
 1.0
 1.9
 5.2
 0.8





-0.6
 3.6
 -0.5
 0.8
0.4
 1.1
-0.6

32 SYNPR synaptoporin 132204 0 2.4

2.2
 0.7
-0.5
 2.2
-0.9
 2.3
0.4
 0.7
0.1
 2.6
1.2
 2.0
0.8
 1.8
1.7
 5.4
0.5
 0.8
0.5
 0.6
-0.0
 3.2
0.8
 0.1
-0.8
 3.0
1.8
 0.1
-0.2
 2.6
-0.3
 0.0
-0.2
 0.6
0.5
 3.2
2.2
 1.6
1.2
-0.4
33 SMPX small muscle protein X-linked 23676 0 2.4 2.2
 2.3
 1.5
 1.9
 1.9
 -0.5
 0.4
 1.1
 1.6
 3.2
 5.3
 1.4
 1.7
 2.4
 -0.5
 2.3
 -0.4
 -0.2
 2.8
 2.2
 -0.0
 3.1

34 GLB1L3 galactosidase beta 1 like 3 112937 0 2.4

2.8
 -0.2
 -0.2
 0.6
0.5
 -0.8
-1.8
 1.5
-1.4
 0.0
 0.5
 0.5
 -0.2
 0.0
 0.3


0.2
 -0.8
 0.9
 0.9
-0.4
 -0.0
-0.4

35 CDH8 cadherin 8 1006 0 2.3 4.4
 3.5
 4.3
 2.2
 0.1
 2.7
 -0.3
 0.8


1.2
 0.6
 -0.0





1.4
 -0.4

36 DYNC1I1 dynein cytoplasmic 1 intermediate chain 1 1780 0 2.3 3.6
 2.3
 4.1
 2.2
0.2
 -0.5
-0.6
 0.3
0.3
 1.2
-0.5
 1.5
-0.8
 1.7
0.6
 1.8
-0.9
 0.1
-0.9
 0.6
-0.4
 2.1
0.2
 0.2
-0.6
 0.6
-0.6
 0.5
-0.9
 0.8
0.2
 0.7
-0.0
 1.9
1.1
 0.6
-0.1
 3.4
0.4
 0.2
-0.4
 -0.6
-0.8
 -0.3
37 MCF2 MCF.2 cell line derived transforming sequence 4168 0 2.3 1.8
 1.5
 1.6
 1.2
0.2
 0.9
0.2
 2.7
0.4
 1.6
0.9
 1.1
0.9
 1.7
0.1
 1.5
0.6
 1.9
-0.1
 0.1
-0.0
 0.7
0.4
 1.3
-0.7
 0.4
0.4
 1.3
-0.3
 -0.2
-0.4
 2.0
0.9
 2.6
1.3
 2.4
1.4
 2.1
2.1
 0.8
-0.1
 -0.7
 0.6
38 RSPO2 R-spondin 2 340419 0 2.3 1.9
 1.5
 1.8
 1.1
 -0.1
 0.5
 -1.5
 1.0
 1.9
 2.1
 -1.0
 1.7
 0.7
 -0.4
 0.8
 -0.2
 0.2
 -0.3
 -0.5
 -0.4
 0.5
 0.4

39 GABRA1 gamma-aminobutyric acid type A receptor subunit alpha1 2554 0 2.3 3.2
 3.0
 2.6
 1.6
1.5
 1.4
1.2
 1.4
1.0
 0.8
0.7
 0.8
0.7
 3.1
2.3
 3.4
2.5
 1.3
0.4
 3.5
2.8
 2.5
0.7
 0.5
0.0
 0.8
0.3
 0.9
0.4
 2.2
0.6
 0.6
0.5
 1.6
1.3
 1.3
1.2
 2.0
2.0
 1.2
1.1
 0.5
40 PDZRN4 PDZ domain containing ring finger 4 29951 0 2.3 3.1
 2.1
 3.3
 2.5
1.0
 1.2
0.4
 0.5
-0.7
 0.2
0.1
 3.0
1.4
 1.2
1.0
 1.1
0.5
 0.9
 0.5
0.2
 0.4
0.1
 0.6
-0.4
 2.7
0.6
 0.8
-0.5
 0.5
0.2
 2.0
-1.0
 0.1
-0.5
 2.0
-0.8
 1.9
1.1
 1.3
1.0
 -0.6
 0.5
41 ADGRB3 adhesion G protein-coupled receptor B3 577 0 2.2 3.0
 2.0
 3.3
 3.1
 1.5
 0.0
 -0.4
 3.0
 4.3
 2.8
 0.9
 0.4
 2.1
 0.5
 -1.5
 -0.6
 2.6
 2.1
 2.0
 1.5
 2.0
 1.0

42 CPNE4 copine 4 131034 0 2.2 3.0
 1.3
 4.0
 2.7
-0.6
 0.9
-0.7
 0.5
 -0.0
 0.9
 3.3
1.5
 2.3
0.4
 1.1
-0.4
 1.9
1.3
 1.5
1.2
 1.4
0.7
 0.1
-0.5
 0.6
0.2
 0.5
-0.1
 -0.4
-0.6
 1.2
0.1
 0.3
0.1
 1.0
0.1
 0.9
0.9

43 HS3ST4 heparan sulfate-glucosamine 3-sulfotransferase 4 9951 0 2.2 1.5
 2.0
 0.6
 2.4
-1.8
 1.3
-1.7
 2.0
0.8
 0.4
-0.9
 1.4
0.9
 -0.9
 -1.6
 -1.0
 1.0
0.1
 1.2
-0.0
 1.3
0.9
 1.6
0.0
 1.1
0.8
 1.2
-0.1
 1.0
0.9
 0.4
0.1
 0.3
0.1
 0.2
-0.3
 -0.4
-0.7
 -1.2
 -0.8
44 TMEM132D transmembrane protein 132D 121256 0 2.2 1.2
 1.3
 0.9
 2.5
2.4
 2.2
2.2
 1.2
0.5
 0.9
0.8
 2.6
0.8
 2.5
1.2
 2.8
1.5
 0.6
0.3
 1.5
1.2
 0.6
0.2
 0.9
0.8
 1.1
1.1
 1.0
0.5
 0.6
0.3
 0.8
0.6
 1.3
0.7
 0.9
0.5
 3.3
0.6
 0.5
0.5
 -0.2
 0.4
45 FGF13-AS1 FGF13 antisense RNA 1 100129662 0 2.2























46 SLC8A2 solute carrier family 8 member A2 6543 0 2.2 0.5
 1.1
 -0.2
 1.8
0.5
 3.2
-0.3
 2.7
1.5
 1.2
-0.3
 2.3
1.8
 2.6
1.8
 4.1
1.8
 2.0
-1.0
 2.3
2.0
 1.4
0.9
 3.3
0.6
 1.0
0.4
 1.0
0.9
 1.0
0.6
 3.6
1.2
 2.9
0.3
 1.0
-0.3
 1.1
0.5
 2.5
1.6
 3.2
 3.9
2.1
47 FHL5 four and a half LIM domains 5 9457 0 2.2 3.5
 4.0
 2.1
 3.4
0.3
 1.6
0.8
 0.5
0.1
 1.8
-1.6
 2.4
-0.3
 0.4
-0.7
 2.1
-1.5
 1.6
-1.3
 1.0
-0.7
 -0.1
-0.2
 1.0
-0.3
 1.0
0.3
 1.0
0.6
 1.8
0.6
 1.1
-0.0
 2.8
0.8
 0.4
-0.3
 0.0
-0.3
 2.5
1.0
1.7
48 GNAO1 G protein subunit alpha o1 2775 0 2.2 2.3
 1.8
 2.2
 1.8
1.2
 2.0
1.9
 1.1
0.4
 1.7
1.7
 3.3
1.8
 2.6
0.0
 1.6
1.4
 -0.0
-0.2
 2.0
1.8
 1.2
1.1
 1.3
0.5
 1.5
1.1
 1.3
0.7
 2.4
2.3
 1.1
1.0
 3.0
1.0
 0.7
0.2
 1.0
0.7
 0.9
0.8
 0.1
-0.2
 0.7
0.4
49 MAGEC3 MAGE family member C3 139081 0 2.2

-0.7




















50 AKAIN1 A-kinase anchor inhibitor 1 642597 0 2.2







-0.5
 2.5
 -0.1
 0.6
 -0.3
 -0.8


0.7
 0.3
 0.0



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