Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-m.7   CYP2C18   cytochrome P450 family 2 subfamily C member 18 
 hsa-u.4   CYP2C18   cytochrome P450 family 2 subfamily C member 18 
 hsa-r.6   CYP2C18   cytochrome P450 family 2 subfamily C member 18 
 hsa-m2.4   CYP2C18   cytochrome P450 family 2 subfamily C member 18 
 hsa-u.4   CYP2E1   cytochrome P450 family 2 subfamily E member 1 
 hsa-u.4   CYP2B6   cytochrome P450 family 2 subfamily B member 6 
 mcc-u.3   CYP2A29   cytochrome P450 family 2 subfamily A member 29 
 mcc-u.3   CYP2C93   cytochrome P450 family 2 subfamily C member 93 
 rno-u.3   Cyp2b2   cytochrome P450, family 2, subfamily b, polypeptide 2 
 rno-u.3   120093077   cytochrome P450 2C6 
 cfa-u.3   100688697   cytochrome P450 2C23-like 
 cfa-u.3   CYP2C41   cytochrome P450 2C41 
 gga-u.3   RP11-400G3.5   Uncharacterized protein 
 gga-u.3   CYP2C18   cytochrome P450 family 2 subfamily C member 18 
 gga-u.3   CYP2C23b   cytochrome P450, family 2, subfamily C, polypeptide 23b 
 dre-u.3   cyp2aa6   cytochrome P450, family 2, subfamily AA, polypeptide 6 
 dre-u.3   cyp2y3   cytochrome P450, family 2, subfamily Y, polypeptide 3 
 cel-u.3   cyp-36A1   putative cytochrome P450 CYP36A1 

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Top 50 coexpressed genes to CYP2C18 (hsa-m.7 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa982   Drug metabolism - cytochrome P450  8 56 6.17
 hsa830   Retinol metabolism  10 51 6.38
 hsa5204   Chemical carcinogenesis - DNA adducts  8 51 6.38
 hsa980   Metabolism of xenobiotics by cytochrome P450  7 61 7.58
 hsa140   Steroid hormone biosynthesis  6 45 6.65

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hsa:CYP2C18 (cytochrome P450 family 2 subfamily C member 18) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-m.7
for
CYP2C18
hsa-u.4
for
CYP2C18
hsa-r.6
for
CYP2C18
hsa-m2.4
for
CYP2C18
hsa-u.4
for
CYP2E1
hsa-u.4
for
CYP2B6
mcc-u.3
for
CYP2A29
mcc-u.3
for
CYP2C93
rno-u.3
for
Cyp2b2
rno-u.3
for
120093077
cfa-u.3
for
100688697
cfa-u.3
for
CYP2C41
gga-u.3
for
RP11-400G3.5
gga-u.3
for
CYP2C18
gga-u.3
for
CYP2C23b
dre-u.3
for
cyp2aa6
dre-u.3
for
cyp2y3
cel-u.3
for
cyp-36A1
1 CYP2C9 cytochrome P450 family 2 subfamily C member 9 1559 23 8.7 19.0
 21.0
 12.4
 4.0
3.3
 5.5
5.4
 9.9
4.6
 3.7
3.1
 13.7
13.0
 20.1
18.0
 6.8
1.7
 1.3
0.8
 20.4
1.4
 20.4
2.6
 12.0
2.6
 2.0
-0.1
 7.3
2.0
2 CCDC198 coiled-coil domain containing 198 55195 0 4.1

3.1



1.2
 1.9

-1.2
 -0.6
 1.3


3 ALDOB aldolase, fructose-bisphosphate B 229 0 4.0 5.2
 3.8
 5.4
 2.6
0.2
 3.2
0.4
 1.0
0.9
 1.8
0.5
 0.5
-0.1
 0.9
0.4
 2.2
0.5
 0.1
-0.3
 0.2
-0.8
 -0.3
-1.2
 4.2
-1.0
 1.1
0.4
 3.3
0.2
 1.0
-1.5
4 GDA guanine deaminase 9615 0 3.9 5.0
 4.1
 4.8
 0.1
 3.0
 -0.4
 1.9
 1.6
 0.6
 -0.0
 -0.5
 -0.1
 0.4
 1.2
 0.1
 0.9
 -0.1
5 ATP10B ATPase phospholipid transporting 10B (putative) 23120 0 3.8 3.9
 3.1
 3.8
 0.3
0.1
 1.2
1.0
 0.9
0.8
 1.4
1.0
 0.6
0.3
 0.7
0.6
 0.7
0.4
 0.8
0.8
 1.6
0.9
 3.4
2.0
 1.8
0.6
 1.3
0.8
 1.6
1.2
 1.4
0.6
6 PIK3C2G phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma 5288 0 3.8

4.1

1.5
 4.1
 2.1
 -0.6

0.4
 1.9
 -0.6
 -0.4
 2.0
7 TM4SF4 transmembrane 4 L six family member 4 7104 0 3.8 4.1
 3.3
 3.9
 0.2
 2.7
 1.0
 2.2
 1.5
 1.5

1.2
 2.3
 3.5
 -0.3
 2.1
8 ADH6 alcohol dehydrogenase 6 (class V) 130 0 3.6 3.9
 2.9
 3.9
 1.4
1.3
 4.3
3.3
 2.2
1.6
 2.5
2.3
 2.4
2.1
 3.6
2.3
 3.5
0.9
 0.6
-0.6
 2.0
1.7
 2.0
1.8
 3.1
1.6
 0.1
 0.3
 -0.4
9 SLC5A1 solute carrier family 5 member 1 6523 0 3.6 3.8
 3.9
 2.7
 1.4
 1.9
 0.3
 3.1
 -0.1
 0.8
 1.0
 0.1
 -0.5
 0.2
 2.8
 -0.9
 0.7
10 CYP3A4 cytochrome P450 family 3 subfamily A member 4 1576 0 3.6 4.6
 4.4
 3.7
 2.4
2.2
 3.9
3.0
 2.3
1.0
 3.5
1.2
 8.8
8.8
 6.9
5.5
 0.0
 -0.1
 1.0
0.3
 2.2
1.5
 4.2
2.3
 2.9
2.1
 3.9
2.4
 1.6
1.5
11 CYP2C19 cytochrome P450 family 2 subfamily C member 19 1557 37 3.6 25.4
 26.7
 17.9
 4.0
3.3
 5.5
5.4
 9.9
4.6
 3.7
3.1
 13.7
13.0
 20.1
18.0
 6.8
1.7
 1.3
0.8
 20.4
1.4
 20.4
2.6
 12.0
2.6
 2.0
-0.1
 7.3
2.0
12 NR1H4 nuclear receptor subfamily 1 group H member 4 9971 0 3.5

2.8

0.8
 3.3
 2.4
 1.1

0.4
 1.9
 1.3
 -0.2
 0.4
13 SLC15A1 solute carrier family 15 member 1 6564 0 3.4 4.4
 3.8
 3.9
 0.9
-0.5
 3.5
-0.1
 0.1
 -0.6
 -0.0
 -1.1
 1.9
-0.2
 -0.1
-0.2
 2.0
-0.6
 3.5
-0.3
 2.2
0.8
 1.4
1.2
 1.6
0.9
 1.4
0.8
14 CLRN3 clarin 3 119467 0 3.4 4.9
 3.2
 5.5
 0.2
 5.4
 0.2
 1.4
 -0.7
 -0.6
 1.4
 -0.3
 0.3
 0.9
 2.7
 -0.2
 0.4
15 SPINK7 serine peptidase inhibitor Kazal type 7 84651 0 3.4 2.2
 2.0
 1.8
 0.4
-0.2
 1.0
-0.5
 1.0
-0.3
 0.5
0.3
 4.4
2.4
 3.4
3.2
 2.8
2.7
 1.2
0.7
 1.8
1.8
 3.0
2.6
 1.9
1.8
 2.0
1.0
 3.3
1.4
 0.1
16 ADGRG7 adhesion G protein-coupled receptor G7 84873 0 3.3 4.5
 4.2
 3.7
 0.2
 4.0
 2.0
 2.3



0.3
 -0.4
 1.2


17 MIA2 melanoma inhibitory activity 2 117153 0 3.3

2.5













18 SLC2A2 solute carrier family 2 member 2 6514 0 3.2 4.4
 4.6
 3.1
 1.4
0.2
 3.7
0.7
 0.4
-0.5
 2.7
0.8
 1.2
-0.4
 2.2
-0.2
 3.6
-0.1
 2.2
0.5
 0.6
0.2
 1.6
1.4
 3.5
1.9
 1.5
0.8
 2.2
1.7
 2.9
2.0
19 SERPINB13 serpin family B member 13 5275 0 3.2 3.2
 2.7
 3.0
 0.4
0.3
 2.0
1.7
 1.7
1.2
 1.5
0.3
 1.8
1.2
 1.8
1.3
 -0.0
-0.3
 0.8
-0.1
 0.6
0.2
 0.5
0.3
 1.1
0.1
 2.2
2.0
 2.1
1.6
 1.8
1.3
20 ACE2 angiotensin converting enzyme 2 59272 0 3.1 3.4
 3.9
 2.1
 -0.1
-0.3
 3.1
0.9
 1.1
-1.5
 1.4
-0.7
 0.3
-0.2
 0.0
-0.2
 0.7
-0.7
 -0.6
-0.7
 -0.1
-0.2
 1.4
0.4
 3.0
1.7
 1.2
-0.1
 1.6
1.3
 0.3
21 AADAC arylacetamide deacetylase 13 0 3.1 5.2
 5.3
 3.7
 1.0
-0.2
 4.4
2.9
 2.7
-0.1
 2.2
0.5
 2.3
0.6
 4.4
0.4
 -0.1
-0.6
 -0.3
-0.7
 1.8
0.8
 1.1
1.1
 3.1
0.4
 3.1
2.7
 2.3
1.8
 1.4
-0.3
22 CEACAM7 CEA cell adhesion molecule 7 1087 0 3.1 2.7
 2.5
 2.2
 1.0
1.0
 3.2
3.2
 1.8
1.0
 1.4
1.1
 1.6
0.8
 0.3
-0.1
 1.3
0.4
 1.2
0.7





23 HABP2 hyaluronan binding protein 2 3026 0 3.1 4.3
 3.5
 4.0
 1.3
 2.1
 1.2
 1.6
 2.1
 2.9
 1.8
 -0.1
 -0.4
 0.4
 1.7
 -0.3
 1.4
24 UNC93A unc-93 homolog A 54346 0 3.1

1.9





1.0
 0.1
 -0.7
 0.2
 0.8

-0.9
25 CYP3A7 cytochrome P450 family 3 subfamily A member 7 1551 0 3.1 3.3
 2.9
 2.8
 2.4
2.2
 3.9
3.0
 2.3
1.0
 3.5
1.2
 8.8
8.8
 6.9
5.5
 0.0
 -0.1
 1.0
0.3
 2.2
1.5
 4.2
2.3
 2.9
2.1
 3.9
2.4
 1.6
1.5
26 SPINK5 serine peptidase inhibitor Kazal type 5 11005 0 3.1 2.6
 2.9
 1.6
 0.3
 -0.2
 -0.3
 1.3
 0.2
 -0.7
 0.4
 -0.3
 1.1
 0.9
 0.1


27 BCO1 beta-carotene oxygenase 1 53630 0 3.1

3.4

0.5
 2.0



2.1
 1.3
 -0.2
 1.4
-0.0
 1.8
1.6
 -0.4
28 UGT2B15 UDP glucuronosyltransferase family 2 member B15 7366 0 3.1 4.4
 3.2
 4.6
 1.5
1.4
 8.0
7.8
 3.8
2.4
 4.6
4.0
 10.2
8.9
 10.7
10.4
 2.5
2.0
 2.0
0.0
 3.8
1.7
 4.0
2.1
 5.0
1.5
 3.0
1.7
 3.8
3.4
 1.3
1.2
29 CERS3 ceramide synthase 3 204219 0 3.0 2.9
 3.1
 2.0
 1.3
1.2
 0.8
0.7
 0.9
0.2
 0.8
-0.2
 1.3
1.1
 0.3
-0.1
 0.1
-0.0
 0.5
-0.0
 0.3
0.3
 0.4
0.4
 0.4
0.2
 1.1
0.5
 0.5
0.5
 0.3
0.1
30 MEP1B meprin A subunit beta 4225 0 3.0 4.1
 3.7
 3.6
 0.7
-2.6
 2.9
1.4
 1.0
-0.2
 2.6
1.2
 -0.2
-0.6
 -0.8
-1.5

-0.3
-0.3
 1.5
0.6
 2.3
1.4
 1.3
0.0
 1.3
1.3
31 APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 339 0 2.9

2.6



-0.3
 0.7
 3.0
 0.4





32 SLC17A4 solute carrier family 17 member 4 10050 0 2.9

4.9
 1.3
0.7
 3.8
1.9
 1.4
1.0
 2.7
2.7
 1.8
1.2
 3.0
1.7
 3.5
0.3
 1.4
-0.4
 0.4
-0.9
 0.8
-0.9
 0.9
-0.4
 1.0
-0.1
 1.7
0.4
 4.2
2.4
33 C3orf85 chromosome 3 open reading frame 85 401081 0 2.9










-0.5
 0.1
 3.3


34 ATP13A4 ATPase 13A4 84239 0 2.9 2.1
 2.2
 1.5
 1.2
0.1
 0.1
-0.8
 2.6
0.7
 2.6
0.7
 0.9
0.5
 0.9
-0.0
 1.2
-0.1
 1.4
0.8
 1.6
0.4
 2.9
0.4
 1.9
0.1
 0.7
0.2
 0.5
-1.4
 0.7
0.4
35 CLDN18 claudin 18 51208 0 2.9 2.1
 2.0
 1.8
 -0.8
 -0.8
 -0.2
 2.5
 2.6
 0.2
 2.3
 0.8
 1.8
 1.3
 -0.1


36 CYP2B6 cytochrome P450 family 2 subfamily B member 6 1555 0 2.9 4.5
 4.0
 3.9
 4.0
3.3
 5.5
5.4
 9.9
4.6
 3.7
3.1
 13.7
13.0
 20.1
18.0
 6.8
1.7
 1.3
0.8
 20.4
1.4
 20.4
2.6
 12.0
2.6
 2.0
-0.1
 7.3
2.0
37 CYP3A43 cytochrome P450 family 3 subfamily A member 43 64816 0 2.9

2.2
 2.4
2.2
 3.9
3.0
 2.3
1.0
 3.5
1.2
 8.8
8.8
 6.9
5.5
 0.0
 -0.1
 1.0
0.3
 2.2
1.5
 4.2
2.3
 2.9
2.1
 3.9
2.4
 1.6
1.5
38 ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 257629 0 2.9 4.2
 4.0
 3.3
 0.1
 5.3
 0.7
 2.3
 0.3
 -0.4
 1.0
 -0.3
 0.5
-0.2
 0.1
-0.3
 2.5
0.0
 0.2
-0.8
 0.9
-0.1
39 SULT1E1 sulfotransferase family 1E member 1 6783 0 2.9 3.6
 3.0
 3.4
 1.4
1.3
 4.3
2.7
 1.9
0.8
 2.8
2.3
 7.6
7.1
 11.3
10.4
 2.6
0.9
 1.2
0.7
 1.5
1.3
 2.6
2.4
 4.5
3.5
 3.0
3.0
 3.6
3.5
 0.9
40 CYP3A5 cytochrome P450 family 3 subfamily A member 5 1577 0 2.9 5.1
 4.0
 5.0
 2.4
2.2
 3.9
3.0
 2.3
1.0
 3.5
1.2
 8.8
8.8
 6.9
5.5
 0.0
 -0.1
 1.0
0.3
 2.2
1.5
 4.2
2.3
 2.9
2.1
 3.9
2.4
 1.6
1.5
41 AKR1B10 aldo-keto reductase family 1 member B10 57016 0 2.9 4.6
 3.7
 4.4
 1.4
1.0
 3.7
3.1
 2.2
1.7
 2.6
2.4
 4.0
2.4
 2.9
2.8
 3.2
0.9
 1.0
0.9
 2.3
1.2
 1.7
1.5
 0.5
0.3
 1.5
1.3
 1.9
0.7
 0.7
-0.5
42 MOGAT2 monoacylglycerol O-acyltransferase 2 80168 0 2.8

2.2
 0.7
 0.3
 0.1
-0.1
 1.0
0.3
 -1.3
-1.5
 -0.1
-0.6
 2.8
0.2
 1.5
0.4
 1.1
1.0
 0.9
0.7
 1.4
0.9
 1.4
0.6
 1.9
1.7
 1.5
1.5
43 BCL2L15 BCL2 like 15 440603 0 2.8 2.5
 2.0
 2.4
 1.4
 0.4
 -1.0
 -0.9

0.5
 1.3





44 POF1B POF1B actin binding protein 79983 0 2.8 3.1
 2.3
 3.1
 -0.3
 0.3
 0.7
 -0.3



2.1
 2.1
 1.2
 0.9
 1.7
45 RDH12 retinol dehydrogenase 12 145226 0 2.8 2.3
 3.1
 0.9
 0.8
0.7
 1.7
1.0
 1.7
0.3
 1.7
0.5
 0.1
0.1
 0.7
0.5
 0.7
-0.4
 1.0
0.7
 1.4
0.1
 0.1
0.1
 1.0
0.4
 2.3
2.3
 2.6
2.4
 1.5
0.3
46 GBA3 glucosylceramidase beta 3 (gene/pseudogene) 57733 0 2.8 3.4
 3.8
 2.3
 1.3
 3.7
 0.2
 1.9

0.3
 0.8


0.6
0.4
 0.8
-0.6
 0.4
-0.6
47 G6PC1 glucose-6-phosphatase catalytic subunit 1 2538 0 2.8 3.4
 3.7
 2.3
 1.4
-2.0
 6.0
-0.2
 -0.0
-0.3
 1.7
-1.3
 1.1
-0.9
 0.4
-1.2
 2.0
-1.5
 0.1
-1.2
 0.8
-0.1
 0.2
-0.3
 1.1
-1.0
 1.9
0.7
 1.5
1.1
48 MUCL3 mucin like 3 135656 0 2.8 3.5
 2.9
 3.4
 -0.6
 1.8



-0.1
 -0.1





49 ACMSD aminocarboxymuconate semialdehyde decarboxylase 130013 0 2.8 2.2
 1.5
 2.3
 2.0
 2.8
 1.1
 1.3
 -0.1
 1.3

-0.2
 -0.0
 1.3
 -0.1
 1.7
 0.3
50 UGT2B28 UDP glucuronosyltransferase family 2 member B28 54490 0 2.8

1.3
 1.5
1.4
 8.0
7.8
 3.8
2.4
 4.6
4.0
 10.2
8.9
 10.7
10.4
 2.5
2.0
 2.0
0.0
 3.8
1.7
 4.0
2.1
 5.0
1.5
 3.0
1.7
 3.8
3.4
 1.3
1.2
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