Orthologous genes in OrthoFinder**

Species Gene Description
 rno-u.3   Rapgef6   Rap guanine nucleotide exchange factor 6 
 rno-r.3   Rapgef6   Rap guanine nucleotide exchange factor 6 
 rno-u.3   Rapgef2   Rap guanine nucleotide exchange factor 2 
 mmu-u.4   Rapgef6   Rap guanine nucleotide exchange factor (GEF) 6 
 mmu-u.4   Rapgef2   Rap guanine nucleotide exchange factor (GEF) 2 
 hsa-u.4   RAPGEF6   Rap guanine nucleotide exchange factor 6 
 hsa-u.4   RAPGEF2   Rap guanine nucleotide exchange factor 2 
 mcc-u.3   RAPGEF6   Rap guanine nucleotide exchange factor 6 
 mcc-u.3   RAPGEF2   Rap guanine nucleotide exchange factor 2 
 cfa-u.3   RAPGEF2   Rap guanine nucleotide exchange factor 2 
 cfa-u.3   RAPGEF6   Rap guanine nucleotide exchange factor 6 
 gga-u.3   RAPGEF6   Rap guanine nucleotide exchange factor 6 
 gga-u.3   RAPGEF2   Rap guanine nucleotide exchange factor 2 
 dre-u.3   rapgef2a   Rap guanine nucleotide exchange factor 2a 
 dre-u.3   rapgef2b   Rap guanine nucleotide exchange factor 2b 
 dre-u.3   rapgef6   Rap guanine nucleotide exchange factor (GEF) 6 
 dme-u.3   PDZ-GEF   PDZ domain-containing guanine nucleotide exchange factor 
 spo-u.3   chc1   putative clathrin heavy chain Chc1 

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Top 50 coexpressed genes to Rapgef6 (rno-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 rno510   N-Glycan biosynthesis  1 50 -
 rno310   Lysine degradation  2 63 -
 rno3018   RNA degradation  2 82 -
 rno3013   Nucleocytoplasmic transport  2 116 -
 rno5132   Salmonella infection  2 254 -

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rno:Rapgef6 (Rap guanine nucleotide exchange factor 6) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

rno-u.3
for
Rapgef6
rno-r.3
for
Rapgef6
rno-u.3
for
Rapgef2
mmu-u.4
for
Rapgef6
mmu-u.4
for
Rapgef2
hsa-u.4
for
RAPGEF6
hsa-u.4
for
RAPGEF2
mcc-u.3
for
RAPGEF6
mcc-u.3
for
RAPGEF2
cfa-u.3
for
RAPGEF2
cfa-u.3
for
RAPGEF6
gga-u.3
for
RAPGEF6
gga-u.3
for
RAPGEF2
dre-u.3
for
rapgef2a
dre-u.3
for
rapgef2b
dre-u.3
for
rapgef6
dme-u.3
for
PDZ-GEF
spo-u.3
for
chc1
1 Setx senataxin 362096 9.8 5.3
 -0.4
 4.9
 1.5
 4.4
 4.1
 6.6
 4.0
 3.9
 5.0
 1.1
 1.3
 2.0
 -0.5
 -0.1
-1.0
2 Kdm5a lysine demethylase 5A 312678 9.1 5.0
 2.2
1.0
 9.1
0.7
 1.9
0.7
 3.6
1.4
 3.6
3.0
 4.9
0.7
 3.4
1.1
 2.8
1.9
 4.4
1.7
 2.0
1.7
 1.1
0.3
 3.0
2.3
 2.9
2.0
 4.6
2.5
 2.9
 1.0
3 Rictor RPTOR independent companion of MTOR, complex 2 310131 8.8 4.8
 1.1
 4.9
 3.4
 4.3
 4.5
 7.0
 2.6
 1.4
 3.4
 -0.3
 1.5
 2.7
2.2
 2.4
1.9
 1.3
0.2
 3.1
4 Atm ATM serine/threonine kinase 300711 7.5 4.1
 -0.4
 5.4
 0.7

10.2
 3.0

-0.6
 -0.4
 1.0
 2.8
 1.9
 2.1
5 Dmxl1 Dmx-like 1 307429 7.4 4.0
 2.8
0.4
 2.7
0.9
 3.1
2.4
 6.7
3.8
 3.1
2.5
 4.2
2.6
 3.5
2.6
 4.2
0.3
 5.8
1.4
 0.8
0.0
 2.8
2.7
 1.6
1.1
 2.4
1.9
 1.6
1.6
 2.6
6 Alg10 ALG10, alpha-1,2-glucosyltransferase 245960 7.3 4.0
 0.7
 1.3
 0.6
 0.3
-0.6
 -1.5
-2.5
 -0.6
 -0.1
 1.0
 2.8
 0.0
 -2.1
 -0.9
 0.7
 -0.2
 -0.2
 1.5
7 Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 361632 7.2 4.0
 1.3
0.2
 4.1
-0.2
 2.0
1.1
 4.5
0.7
 2.9
0.8
 6.2
1.5
 3.5
1.4
 2.7
0.5
 2.1
2.0
 1.8
1.6
 2.6
0.8
 3.0
1.5
 2.4
0.6
 0.1
-2.3
 2.5
8 Ahctf1 AT hook containing transcription factor 1 360886 7.2 4.0
 -0.1
 1.8
 1.0
 3.0
 2.8
 4.7
 2.4
 2.2
 2.5
 1.0
 0.5
 1.7
 -0.2
 -1.1
 2.4
9 Tasor transcription activation suppressor 680155 7.1 3.9
 0.4
 2.5
 0.9
 2.3
 -0.1
 2.9
 2.0
 0.6
 2.1
 2.0
 2.7
 3.7
2.5
 1.2
0.5
 1.8
1.0

10 Ankhd1 ankyrin repeat and KH domain containing 1 100529260 7.0 3.9
 4.6
0.6
 4.3
3.0
 3.0
1.3
 5.4
3.8
 4.8
2.4
 5.1
2.3
 3.7
2.5
 5.0
2.6
 2.9
2.4
 5.1
2.3
 1.4
0.3
 1.3
 0.7
 1.7
 4.4
11 Chd1 chromodomain helicase DNA binding protein 1 308215 6.9 3.8
 1.3
0.2
 4.2
3.8
 2.5
1.6
 5.3
4.7
 4.2
3.2
 5.6
5.4
 4.6
1.5
 2.9
2.0
 5.2
3.0
 2.2
0.2
 1.5
1.0
 4.4
2.7
 2.0
-0.1
 1.3
-1.6
 3.6
12 Smg1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 691397 6.7 3.7
 0.5
 5.2
 3.3
 4.0
 2.1
 5.2
 2.3
 1.4
 1.6
 2.7
 1.4
 0.8
 1.1
 1.8
 2.1
13 Ash1l ASH1 like histone lysine methyltransferase 310638 6.7 3.6
 2.3
 5.6
 2.3

4.2
 2.3
 3.7
 2.8
 2.7
 2.1
 0.6
 3.5
 1.1
 7.0
14 Prr14l proline rich 14-like 305466 6.6 3.6
 3.1
 4.6
 1.5
 2.5
 2.1
 2.4
 3.3
 3.7
 3.7






15 Avl9 AVL9 cell migration associated 312371 6.4 3.5
 0.5
 3.6
 2.4
 3.1
 1.0
 1.8
 2.5
 3.6
 3.6
 2.6
 0.5
 1.6
 -1.7
 -0.4
 -0.2
 1.3
16 LOC100361083 hypothetical LOC100361083 100361083 6.3 3.5
 0.9
 5.8
 1.6
 3.0
 1.5









0.1
17 Tasor2 transcription activation suppressor family member 2 361269 6.3 3.5
 2.0
 2.7
 2.2

3.1
 2.6
 4.9
 4.6
 2.8
 0.2
 1.9
 -0.6
 0.5

18 Mga MAX dimerization protein MGA 499874 6.3 3.5
 -0.2
 4.6
 0.6

3.5
 2.3
 2.8
 5.0
 2.3
 2.2
 1.7
 -0.5
 0.5
-0.2
19 Nsd1 nuclear receptor binding SET domain protein 1 306764 6.2 3.4
 1.6
 4.9
 0.3

2.9
 2.9
 2.2
 1.6
 5.4
 0.3
 1.3
0.8
 1.7
1.5
 0.5
0.5
1.0
20 Bbx BBX high mobility group box domain containing 303970 6.2 3.4
 -0.5
 5.5
 1.0
 3.2
 1.7
 3.2
 1.8
 3.3
 2.2
 0.1
 1.0
 -0.1
 -0.4
 0.9

21 Phip pleckstrin homology domain interacting protein 315843 6.1 3.4
 1.7
0.2
 6.2
3.1
 1.0
0.6
 5.9
5.0
 2.4
2.0
 5.6
4.4
 2.9
2.9
 3.0
1.9
 7.9
3.3
 1.8
1.0
 2.7
1.6
 1.0
-0.8
 1.6
0.5
 1.5
-0.2
 2.7
22 Ltn1 listerin E3 ubiquitin protein ligase 1 288308 6.1 3.3
 0.5
 5.3
 0.2
 5.0
 0.7
 3.4
 0.1
 2.0
 2.7
 1.3
 1.6
 1.2
 -0.4
 -0.2
 2.9
 -0.6
23 Lmbrd2 LMBR1 domain containing 2 499539 6.1 3.3
 2.9
 5.4
 0.2
 4.8
 0.3
 3.4
 4.1
 3.6
 5.1
 1.8
 1.8
 1.9
-0.2
 2.9
0.3
 1.0
-1.4
-0.7
24 Ubr3 ubiquitin protein ligase E3 component n-recognin 3 311115 6.0 3.3
 3.0
 2.6
 2.1
 5.0
 2.5
 4.3
 2.3
 3.7
 3.0
 2.0
 2.5
 1.5
 1.4
 -0.2
 6.2
25 Klhl11 kelch-like family member 11 287706 5.9 3.3
 0.2
 3.9
 0.3
 0.4
 -0.1
 3.3
 2.3
 2.1
 2.6
 2.0
 -0.7
 1.3
 0.4
 -0.2

26 Xrn1 5'-3' exoribonuclease 1 300944 5.9 3.3
 -0.1
 5.8
 0.8
 6.2
 2.7
 3.2
 3.2
 2.9
 7.4
 1.2
 2.2
 2.3
 -0.4
 -0.1
 2.3
27 Vps13c vacuolar protein sorting 13 homolog C 363087 5.9 3.2















28 Akap11 A-kinase anchoring protein 11 498549 5.9 3.2
 3.2
 2.7
 2.6
 5.2
 0.9
 5.1
 4.3
 2.2
 3.6
 0.9
 3.9
 2.5
 3.3
 0.1

29 Vcpip1 valosin containing protein interacting protein 1 286761 5.9 3.2
 2.3
 2.4
 4.3
 2.7
 2.4
 -0.1
 1.6
 2.5
 3.8
 2.7
 0.5
 0.1
 -1.0
 0.4

30 Shprh SNF2 histone linker PHD RING helicase 308282 5.9 3.2
 2.0
 5.4
 -0.5
 6.2
 0.3
 3.4
 2.3
 0.5
 3.0
 0.8
 0.9
 0.4
 -1.1
 0.7
 1.2
 -0.0
31 Chd9 chromodomain helicase DNA binding protein 9 307726 5.9 3.2
 1.2
1.0
 4.7
3.2
 1.3
1.2
 3.8
3.6
 3.3
3.2
 3.8
2.7
 5.2
2.0
 3.8
3.4
 4.0
2.9
 3.8
3.4
 2.5
1.2
 2.2
1.5
 4.2
2.0
 2.4
1.1
 5.0
32 Thoc2 THO complex 2 313308 5.8 3.2
 0.4
-0.4
 5.9
2.2
 -0.3
-0.7
 3.2
 0.6
 4.3
 0.4
 2.6
 3.7
 0.6
 0.6
 1.0
 1.0
 -0.5
 1.3
 0.3
-0.3
33 Gcc2 GRIP and coiled-coil domain containing 2 309798 5.8 3.2
 1.6
 5.3
 1.8
 3.4
 1.5
 3.1
 3.1
 2.9
 3.0
 1.2
 2.4
 2.3
 1.1
 3.1
 3.2
34 Map3k2 mitogen activated protein kinase kinase kinase 2 171492 5.8 3.2
 1.0
0.6
 4.0
2.5
 2.3
1.7
 2.3
1.5
 2.8
2.1
 6.4
1.5
 2.5
-0.2
 1.0
0.3
 1.6
-0.0
 4.5
1.9
 0.1
0.0
 2.6
1.0
 1.3
0.4
 1.6
1.3

35 Vps13a vacuolar protein sorting 13 homolog A 309243 5.8 3.2
 1.5
 7.3
2.9
 1.1
0.7
 6.7
4.7
 2.0
1.2
 3.5
2.0
 2.8
2.1
 3.9
3.0
 5.1
3.7
 0.9
0.2
 2.2
0.8
 0.3
-0.0
 1.6
1.0
 2.3
1.5
 1.1
 4.0
36 Zfp292 zinc finger protein 292 50552 5.8 3.2
 0.9
 5.3
 0.7
 3.9
 1.3
 4.7
 2.8
 0.1
 1.9
 1.3
 0.4
 2.7
0.7
 0.9
0.8
 2.9
0.2

37 Ascc3 activating signal cointegrator 1 complex subunit 3 309887 5.7 3.2
 1.3
0.8
 4.6
0.6
 2.4
2.1
 4.5
1.1
 0.8
0.3
 0.8
 0.3
 3.8
1.3
 3.1
1.3
 3.5
-1.1
 2.5
0.2
 -0.3
-1.0
 1.6
-0.9
 1.9
0.1
 1.7
0.4
 0.6
38 Zdhhc21 zinc finger DHHC-type palmitoyltransferase 21 298184 5.7 3.1
 1.8
 -0.8
 1.1
 1.7
 0.4
 1.8
 1.6
 1.0
 1.0
 -1.0
 -1.1
 -0.4
 -0.2
 0.4

39 Chd2 chromodomain helicase DNA binding protein 2 308738 5.7 3.1
 1.3
0.2
 4.2
3.8
 2.5
1.6
 5.3
4.7
 4.2
3.2
 5.6
5.4
 4.6
1.5
 2.9
2.0
 5.2
3.0
 2.2
0.2
 1.5
1.0
 4.4
2.7
 2.0
-0.1
 1.3
-1.6
 3.6
40 Bdp1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 294687 5.7 3.1
 0.8
 3.7
 1.6
 7.3
 2.1
 4.6
 3.6
 3.9
 4.8
 0.8
 0.4
 -0.5
-1.1
 0.9
0.2
 -0.2
-1.6
 0.3
 0.5
41 Tnks tankyrase 290794 5.7 3.1
 4.5
2.4
 4.2
3.5
 2.1
1.3
 4.9
4.7
 3.0
2.3
 4.1
3.6
 3.7
2.5
 1.5
1.4
 2.1
0.4
 2.1
1.3
 2.3
1.3
 2.3
0.6
 1.7
1.5
 1.5
0.7
 1.7
42 Slc4a7 solute carrier family 4 member 7 117955 5.7 3.1
 0.7
0.7
 1.1
0.5
 1.7
1.1
 2.4
1.6
 1.3
0.2
 2.8
0.4
 2.1
1.9
 1.6
1.5
 2.0
1.6
 2.3
1.9
 2.3
1.3
 1.8
1.6
 2.1
1.2
 1.3
0.8
 1.3
-0.8
 1.8
0.5
43 Uhmk1 U2AF homology motif kinase 1 246332 5.6 3.1
 0.8
 3.7
 0.7
 1.4
 -0.2
 4.2
 2.9
 2.6
 3.7
 2.7
 0.3
 0.3
 -2.2
 -1.4

44 Dcp2 decapping mRNA 2 291604 5.6 3.1
 1.7
 0.8
 2.7
 3.5
 0.8
 3.1
 0.6
 -1.6
 -0.1
 0.5
 -1.4
 -1.6
 0.1
 0.6
 7.4
 0.6
45 Atp13a3 ATPase 13A3 678704 5.5 3.0
 0.7
0.6
 1.9
-0.5
 0.2
-0.3
 3.2
0.0
 2.2
0.8
 1.2
-0.0
 1.7
0.6
 3.0
0.1
 2.4
0.4
 2.0
1.0
 2.4
-0.1
 0.8
0.1
 0.2
-0.7
 0.8
0.3
 1.9
 2.2
46 Alms1 ALMS1, centrosome and basal body associated protein 297408 5.5 3.0
 -0.9
 2.0
 -1.1
 2.6
 1.2
 1.3
 0.8
 4.4
 0.1
 1.1
 1.2




47 Son SON DNA and RNA binding protein 304092 5.5 3.0
 1.5
 3.3
 2.0
 3.8
 2.4
 4.4
 4.1
 4.2
 5.4
 2.0
 1.4
 1.1
 1.6
 2.9
 1.9
48 Lrba LPS responsive beige-like anchor protein 361975 5.5 3.0
 2.0
1.9

1.9
1.1
 4.3
1.7
 1.4
0.9
 2.1
0.3
 2.5
2.5
 1.4
0.9
 0.9
-0.5
 3.3
0.2
 1.8
0.4
 1.4
0.9
 0.4
-0.6
0.9
49 Dennd1b DENN domain containing 1B 289051 5.5 3.0
 1.8
0.3
 5.8
-0.3
 2.8
1.9
 0.7
 1.3
 2.9
-0.4
 3.3
2.2
 3.1
0.8
 0.7
-1.7
 0.9
0.5
 2.9
1.1
 0.4
0.3
 1.0
0.5
 2.0
-0.0
 2.2
50 Pbrm1 polybromo 1 306254 5.5 3.0
 1.0
 3.0
 0.9
 5.1
 2.3
 4.7
 2.5
 4.2
 5.6
 4.2
 0.5
 1.1
0.5
 3.1
0.7
 0.7
-0.6
 0.1
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