Orthologous genes in OrthoFinder**

Species Gene Description
 mmu-u.4  Txnrd1  thioredoxin reductase 1 
 mmu-r.6  Txnrd1  thioredoxin reductase 1 
 mmu-m.5  Txnrd1  thioredoxin reductase 1 
 mmu-u.4  Txnrd3  thioredoxin reductase 3 
 mmu-u.4  Txnrd2  thioredoxin reductase 2 
 rno-u.3  Txnrd3  thioredoxin reductase 3 
 rno-u.3  Txnrd2  thioredoxin reductase 2 
 rno-u.3  Txnrd1  thioredoxin reductase 1 
 hsa-u.4  TXNRD2  thioredoxin reductase 2 
 hsa-u.4  TXNRD3  thioredoxin reductase 3 
 hsa-u.4  TXNRD1  thioredoxin reductase 1 
 mcc-u.3  TXNRD3  thioredoxin reductase 3 
 mcc-u.3  TXNRD2  thioredoxin reductase 2 
 mcc-u.3  TXNRD1  thioredoxin reductase 1 
 cfa-u.3  TXNRD2  thioredoxin reductase 2 
 cfa-u.3  TXNRD3  thioredoxin reductase 3 
 cfa-u.3  TXNRD1  thioredoxin reductase 1 
 gga-u.3  TXNRD1  thioredoxin reductase 1 
 gga-u.3  TXNRD2  thioredoxin reductase 2 
 gga-u.3  TXNRD3  thioredoxin reductase 3 
 dre-u.3  txnrd2.2  thioredoxin reductase 2, tandem duplicate 2 
 dre-u.3  txnrd3  thioredoxin reductase 3 
 dme-u.3  Trxr-2  thioredoxin reductase 2 
 dme-u.3  Trxr-1  Thioredoxin reductase-1 
 cel-u.3  trxr-1  Thioredoxin reductase 1 
 cel-u.3  trxr-2  putative glutathione reductase 2 

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Top 50 coexpressed genes to Txnrd1 (mmu-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 mmu5014   Amyotrophic lateral sclerosis  9 325 6.42
 mmu5169   Epstein-Barr virus infection  7 189 5.90
 mmu5012   Parkinson disease  7 238 5.24
 mmu5022   Pathways of neurodegeneration - multiple diseases  7 430 3.61
 mmu5010   Alzheimer disease  6 351 3.26

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mmu:Txnrd1 (thioredoxin reductase 1) External Links;


Show/Hide Columns:          
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID
Other ID CoexPub LINK Target Reference

mmu-u.4
for
Txnrd1


mmu-r.6
for
Txnrd1


mmu-m.5
for
Txnrd1


mmu-u.4
for
Txnrd3


mmu-u.4
for
Txnrd2


rno-u.3
for
Txnrd3


rno-u.3
for
Txnrd2


rno-u.3
for
Txnrd1


hsa-u.4
for
TXNRD2


hsa-u.4
for
TXNRD3


hsa-u.4
for
TXNRD1


mcc-u.3
for
TXNRD3


mcc-u.3
for
TXNRD2


mcc-u.3
for
TXNRD1


cfa-u.3
for
TXNRD2


cfa-u.3
for
TXNRD3


cfa-u.3
for
TXNRD1


gga-u.3
for
TXNRD1


gga-u.3
for
TXNRD2


gga-u.3
for
TXNRD3


dre-u.3
for
txnrd2.2


dre-u.3
for
txnrd3


dme-u.3
for
Trxr-2


dme-u.3
for
Trxr-1


cel-u.3
for
trxr-1


cel-u.3
for
trxr-2

1 Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) 76650 19 9.1 9.0
4.0
-0.5
0.9
0.0
-0.7
8.9
0.9
0.6
12.4
0.7
-0.2
5.0
-1.1
0.5
5.5
3.1
-0.4
-0.4
1.5
0.5
-0.4
0.6


2 Eid3 EP300 interacting inhibitor of differentiation 3 66341 0 7.7 9.0
2.6
0.8
0.4
0.5
-0.8
0.3
0.1
0.8
0.1
3.9
0.3
-0.1
-0.2
1.2
-0.5
9.8
-1.8
2.1
-0.6
1.6
-0.8
3.1
-1.2
0.3
-0.4
0.1
-1.1
2.8
-1.2
0.2
-0.4
-0.4
1.9
2.3
0.3
-1.9
0.0
0.4
3 Gclm glutamate-cysteine ligase, modifier subunit 14630 26 7.6 8.1
3.0
1.7
2.9
0.7
0.4
5.4
0.7
-0.0
11.1
1.3
0.0
1.9
-0.5
0.5
3.3
1.7
0.7
1.5
0.4
3.5
-0.1
4.0
-0.6
-0.5
4 Gsr glutathione reductase 14782 19 6.9 6.8
3.1
-0.4
0.7
0.2
0.7
7.9
0.6
-1.0
8.7
0.9
0.9
0.3
1.0
-0.7
6.1
1.3
-0.3
0.2
0.5
4.5


2.4
0.6
5 Eif4g1 eukaryotic translation initiation factor 4, gamma 1 208643 0 6.8 4.5
4.2
1.1
1.8
1.1
-0.1
1.8
0.9
3.9
0.7
1.3
0.8
2.4
-0.1
-0.3
-0.2
-1.5
1.7
1.5
1.0
-1.7
0.6
-1.2
2.0
0.7
0.8
0.6
0.3
-0.4
1.7
-1.3
1.4
-0.1
3.5
2.9
0.4
-0.2
-0.2
-0.3
2.5
0.1
6 Gclc glutamate-cysteine ligase, catalytic subunit 14629 30 6.5 7.1
2.5
1.6
0.8
-0.3
1.2
7.4
0.3
0.6
6.4
1.8
1.0
-0.1
0.1
0.5
3.1
3.0
1.8
0.3
0.5
4.1
-0.1
4.5
2.6
2.6
7 Mdm2 transformed mouse 3T3 cell double minute 2 17246 0 6.4 5.9
3.1
-2.3
-2.0
0.3
-0.7
5.4
-0.1
-1.0
3.2
-2.2
-2.2
3.1
-1.4
-0.5
1.2
0.2
1.1
0.2
0.2
0.8




8 Eaf1 ELL associated factor 1 74427 0 6.3 6.6
2.6
0.8
-0.3
1.4
0.4
5.5
0.2
-1.5
-0.6
-1.8
1.9
-1.2
-0.2
-1.1
-0.0
-0.2
3.0
0.2
-0.6
-2.0
1.1
-0.3
2.8
-0.4
1.1
0.3
0.0
-0.6
1.5
-0.0
0.3
-0.2
0.8
-1.2
0.2
-0.9
-0.9
2.1
9 Prdx1 peroxiredoxin 1 18477 0 5.9 7.0
2.0
0.7
0.3
4.5
3.9
0.9
0.4
4.5
2.1
6.2
1.3
1.8
1.8
1.9
0.3
5.8
2.5
1.4
1.1
1.0
0.2
2.2
1.7
1.9
1.7
1.1
0.6
3.4
0.8
1.9
0.1
3.0
-0.3
0.9
0.9
-0.2
-0.2
4.5
2.5
1.2
-0.0
8.6
2.2
1.4
1.2
2.4
0.3
10 Hmox1 heme oxygenase 1 15368 0 5.8 5.5
2.7
-0.1
-0.6
0.2
0.1
3.0
0.2
0.4
-0.2
3.8
0.2
0.1
-0.4
1.3
-1.4
5.6
0.5
1.0
-0.3
1.6
0.4
0.7
0.7
1.5
0.6
0.4
0.1
1.7
1.0
1.5
0.3
-0.8
-1.6
-0.3
-0.7
2.4
-0.8
0.5
0.1
-0.6
-1.8


11 Esd esterase D/formylglutathione hydrolase 13885 0 5.6 5.9
2.3
-0.4
0.2
-0.3
1.4
1.6
0.9
2.1
-0.2
1.0
0.4
0.9
1.3
1.2
2.3
-0.4
0.4
-0.5
0.1
-0.2
0.1
1.7
-0.0
0.3
12 Sqstm1 sequestosome 1 18412 0 5.6 6.7
1.8
0.1
1.5
1.2
1.4
5.1
0.7
-1.2
9.1
-0.6
0.6
2.0
0.2
0.4
1.7
0.4
0.2
-0.3
-1.4
-0.1
-0.1
4.2
1.2
-0.1
2.4
0.4
13 Nol9 nucleolar protein 9 74035 0 5.4 2.3
4.2
1.5
0.2
-0.6
-0.2
2.8



0.9
-0.4
0.4
-0.5
-0.1
-0.6
-1.5
-0.2
-1.6
-0.2
0.8
0.6
0.0
-0.3
-0.0
14 Nqo1 NAD(P)H dehydrogenase, quinone 1 18104 0 4.9 5.1
2.1
0.6
1.0
-0.3
-1.1
6.5
0.8
0.3
10.7
-0.4
0.1
1.1
-0.9
0.2
4.4
0.8
-0.1
-0.1
-0.8
1.3




15 Hspa9 heat shock protein 9 15526 0 4.9 5.1
2.0
2.9
0.7
2.0
-0.0
2.4
0.7
2.9
-0.1
4.8
2.0
0.7
0.5
-0.4
-0.5
4.4
2.4
0.8
0.4
0.8
0.3
3.5
1.7
0.6
0.5
1.2
0.4
3.1
2.2
2.1
0.3
1.6
-1.1
2.5
2.0
0.7
0.6
4.2
3.1
0.7
0.0
5.0
3.3
3.5
1.1
2.7
1.1
16 Psmd11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 69077 0 4.9 5.1
2.0
0.6
0.8
0.5
-0.1
5.0
-0.5
-2.2
4.8
1.0
-2.0
2.3
0.2
-0.4
3.2
1.2
-1.1
1.3
1.4
0.7
4.1
2.7
-0.5
1.1
0.2
1.2
17 Pgd phosphogluconate dehydrogenase 110208 0 4.8 4.7
2.1
1.7
1.2
0.4
2.1
4.2
-0.5
-0.3
6.8
0.3
-0.4
3.5
0.9
1.0
1.3
0.5
-1.5
1.4
0.6
5.0
-0.2
4.4
-0.8
1.6
18 Ftl1 ferritin light polypeptide 1 14325 0 4.7 4.5
2.2
-0.5
-0.7
1.9
1.9
0.9
0.4
0.1
-0.2
4.3
2.3
-0.6
-1.1
-0.7
-0.8
6.7
5.4
-1.2
-1.7
-0.0
-0.3
0.9
0.1
0.1
-0.0
0.3
-0.0
2.5
2.3
1.2
-0.3
-0.4
1.1
-0.2
2.3
2.0
1.5
0.6
0.7
-0.3
0.9
0.3
19 Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 108147 0 4.7 2.7
3.2
1.8
1.0
-0.3
1.9
4.5
1.2
2.2
0.9
0.2
1.2
-0.1
-0.8
1.4
-1.0
-1.3
1.8
-0.2
0.2
0.1
-0.6
0.4
0.0
1.1
20 Ibtk inhibitor of Bruton agammaglobulinemia tyrosine kinase 108837 0 4.7 2.3
3.4
-0.3
1.2
-0.5
1.5
1.6
0.4
0.8
1.2
0.2
1.5
0.1
-1.7
0.5
-0.4
0.6
0.9
2.0
0.8
2.1
0.4
1.4


21 Aqr aquarius 11834 0 4.7 1.6
3.8
0.1
0.1
-1.6
0.8
0.8
-0.3
-1.6
0.6
0.2
-0.9
2.1
-1.1
-0.8
-0.9
1.6
0.9
1.9
-1.3
-0.2
-0.5
-0.5
2.3
0.3
22 Twf1 twinfilin actin binding protein 1 19230 0 4.6 3.4
2.7
0.2
-1.6
0.3
-2.1
1.1
-1.3
1.1
-1.3
2.9
-0.3
0.7
-1.0
-1.2
-1.3
1.7
1.4
-0.6
-0.9
1.5
-2.2
-0.1
2.3
1.3
-0.1
-0.0
-1.3
1.8
-0.0
0.6
0.1
0.8
0.8
0.1
1.1
0.9
0.1
23 Ecpas Ecm29 proteasome adaptor and scaffold 230249 0 4.6 2.0
3.5
0.9
1.7



0.2
-0.7
3.0
-0.4
0.5
3.8
1.0
0.1
2.5
0.6
-0.0
1.2
0.5
2.6
0.0
0.4
1.7
-0.8
24 Nup50 nucleoporin 50 18141 0 4.6 4.3
2.2
0.7
-0.2
1.0
-0.6
3.4
0.4
-1.2
2.8
-0.3
-1.1
1.0
-0.1
-0.3
4.8
1.4
-1.1
1.7
0.8
2.7
-0.5
2.5


25 Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 22628 0 4.5 4.2
2.2
0.6
0.6
0.3
0.2
1.4
0.4
0.4
-0.8
3.1
3.1
0.6
0.5
-1.0
-1.0
3.3
1.5
0.6
0.1
0.1
-0.3
5.0
2.7
0.9
0.5
1.3
1.2
3.2
1.5
-0.0
-0.1
0.2
-0.2
3.5
3.2
2.0
0.7
1.1
1.0
-0.3
-1.0
0.2
-0.3
1.0
0.4
0.5
-0.8
26 Mapk6 mitogen-activated protein kinase 6 50772 0 4.5 4.4
2.1
2.1
-1.8
1.9
-1.0
2.1
-1.4
-1.7
2.5
0.0
-1.1
2.1
-1.1
-0.4
1.5
1.1
0.8
1.5
0.0
-0.2




27 Crkl v-crk avian sarcoma virus CT10 oncogene homolog-like 12929 0 4.5 2.7
3.0
-0.7
-1.1
-0.3
-1.6
0.7
0.1
0.0
-1.2
2.8
2.2
1.5
-1.0
-1.1
-1.2
4.2
1.5
0.1
-0.8
0.2
-1.7
2.9
0.5
0.4
-0.7
1.6
0.3
2.7
1.3
0.9
-1.1
0.0
-0.3
1.9
1.8
0.0
-1.5
3.3
1.9
-0.2
-1.1
-1.0
-0.2
28 Kpna4 karyopherin (importin) alpha 4 16649 0 4.4 3.3
2.5
-0.1
-0.6
0.1
-0.7
0.9
0.9
-0.4
-1.1
3.2
1.5
-0.7
-1.1
0.6
-0.8
3.7
2.3
-1.0
-1.3
0.2
-0.3
2.4
1.8
-1.0
-1.3
0.2
-0.2
0.8
0.4
0.3
-1.2
-0.9
-1.2
2.8
2.3
1.1
0.8
2.1
1.9
-0.0
-0.5
-0.9
0.2
29 Txn1 thioredoxin 1 22166 0 4.4 4.9
1.6
0.3
-0.3
-1.6
-0.8
3.7
-0.8
-0.1
6.2
-0.2
-0.9
2.5
-1.1
-1.0
2.7
2.6
-1.7
0.5
0.8
0.5
2.7
0.6
0.4
-1.1
5.0
0.7
1.6
0.4
2.0
-0.2
30 Dhx29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 218629 0 4.3 2.7
2.8
0.8
-0.2
-1.0
0.4
4.0
0.8
-0.5
0.9
1.3
-0.6
2.3
-0.4
0.1
0.3
1.2
0.4
1.2
1.0
-0.2




31 G3bp1 GTPase activating protein (SH3 domain) binding protein 1 27041 0 4.3 5.3
1.3
1.1
-0.6
-2.1
-2.1
0.5
-1.0
-0.4
-0.6
3.8
2.2
-1.1
-1.7
0.1
-1.0
3.3
2.6
0.4
-0.7
0.3
-0.7
3.2
3.0
-0.3
-2.1
0.0
3.0
1.9
1.8
-0.1
-0.8
-1.0
1.9
1.8
-0.1
-0.7
2.8
2.6
0.1
1.8
-0.3
0.4
32 Vcp valosin containing protein 269523 0 4.3 5.8
1.0
2.3
2.3
1.4
1.3
1.3
0.7
1.3
1.0
7.0
1.2
1.4
1.1
0.7
-0.1
4.8
0.5
0.4
-0.2
1.6
0.9
4.5
-2.6
0.2
-0.0
0.4
0.1
3.0
1.6
1.3
0.8
0.3
-0.5
1.9
1.3
1.7
1.6
4.1
0.9
0.9
-0.2
2.9
-0.3
1.2
-0.4
0.2
-0.6
33 Tuba1c tubulin, alpha 1C 22146 0 4.3 4.3

1.4
0.9
0.8
0.7
0.5
0.3
1.5
0.4
4.7
1.2
0.6
0.4
0.0
-0.3
2.6
1.3
1.3
0.9
0.6
0.5
2.9
2.4
1.0
0.6
0.6
-0.2
1.5
1.4
0.9
0.8
1.1
0.1
2.2
1.6
0.8
0.7
3.8
3.0
0.8
0.8
3.4
1.5
1.8
1.2
1.0
0.8
34 Hnrnpab heterogeneous nuclear ribonucleoprotein A/B 15384 0 4.3 4.9
1.5
1.8
1.8
0.5
-0.1
1.4
0.3
0.3
-0.1
4.3
1.3
0.9
-0.2
0.4
0.4
1.5
-0.5
1.4
1.2
-0.6
-2.0
1.9
1.6
1.5
1.5
0.1
-0.2
3.5
0.6
0.6
-0.9
0.4
-0.7
1.7
0.7
0.0
-0.3
1.9
1.7
0.0
0.4
2.1
1.3
35 Supt16 SPT16, facilitates chromatin remodeling subunit 114741 0 4.3 2.3
3.0
0.4
-0.8
0.0
-0.5
2.8
-0.9
0.7
1.4
0.8
-1.1
2.1
-1.5
-0.7
1.7
0.2
0.6
1.1
-0.2
2.6
-0.2
1.6
-0.5
0.3
36 Psmd7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 17463 0 4.3 3.4
2.4
0.3
0.1
-0.0
-0.2
4.6
0.2
-0.2
3.0
1.0
-1.9
1.4
-1.0
-0.6
1.5
0.9
-1.0
1.5
1.7
2.0
-0.0
1.7
1.9
2.3
37 Ubtf upstream binding transcription factor, RNA polymerase I 21429 0 4.3 0.8
3.8
0.4
1.5
-2.4
2.7
2.3
-0.3
-1.0
0.3
-0.8
0.2
-0.9
1.9
0.6
-0.0
-0.5
-2.6
-2.1
0.1
-0.1




38 Nploc4 NPL4 homolog, ubiquitin recognition factor 217365 0 4.2 4.9
1.5
1.5
0.6
2.4
1.0
5.1
2.2
-1.2
3.5
1.0
1.9
1.3
1.0
0.2
2.3
-0.4
-2.0
0.5
0.9
4.0
0.0
2.2
0.8
0.1
0.1
-0.7
39 Usp10 ubiquitin specific peptidase 10 22224 0 4.2 4.0
2.0
2.1
0.8
-1.0
1.8
4.9
-0.2
-0.8
1.9
-0.1
-0.6
2.1
-0.4
-1.3
1.6
-0.3
0.8
1.8
-0.1
2.2
0.2
1.5


40 Trp53 transformation related protein 53 22059 0 4.2 2.3
2.9
-0.7
0.0
-2.1
1.1
2.7
0.3
0.7
-0.1
0.4
0.3
-1.5
0.2
0.7
0.0
0.6
0.2
-1.2
-0.4
0.0
-0.6
1.5


41 Ddx21 DExD box helicase 21 56200 0 4.2 4.7
1.5
1.7
-0.2
-0.3
-0.5
4.5
-0.8
-0.6
2.8
0.5
-1.5
1.9
-1.0
0.8
0.5
1.7
-0.7
3.5
-1.1
0.2




42 Nopchap1 NOP protein chaperone 1 28109 0 4.1 3.4
2.2
1.5
-0.7
0.1
-0.9
1.9
-1.2
1.1
0.7
-0.7
0.6
0.6
-1.7
1.5
3.3
1.0
-1.2
1.4
1.1
-1.6




43 Psmd1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 70247 0 4.1 5.6
1.0
1.5
0.4
0.3
1.0
3.9
1.2
-0.8
5.2
0.9
-0.2
4.4
0.5
-0.6
3.1
1.0
-0.6
1.9
0.2
3.2
0.1
3.2
0.8
1.2
44 Ikbkg inhibitor of kappaB kinase gamma 16151 0 4.1 3.2
2.3
-0.7
1.6
-1.4
0.3
2.5
2.4
-1.1
2.5
-0.2
-0.2
1.3
1.1
0.3
1.2
-0.2
-0.2
-1.0
-0.2
-0.1




45 Zfand5 zinc finger, AN1-type domain 5 22682 0 4.1 4.0
1.9
0.5
-0.9
1.9
1.3
2.3
1.0
1.1
1.0
2.5
-0.7
-0.4
-1.0
-0.7
-1.6
4.7
2.5
-0.2
-1.0
0.4
-0.3
1.2
0.8
0.9
-1.0
0.2
-0.1
1.2
0.1
0.9
0.5
0.6
0.1
0.8
-0.3
0.2
-0.2
1.3
-0.9


0.3
-0.9
46 Eif4a1 eukaryotic translation initiation factor 4A1 13681 0 4.1 4.9
1.4
1.2
0.2
0.4
-0.4
0.9
-0.3
0.0
-0.7
3.8
0.8
-0.5
-0.8
1.2
0.4
2.1
0.9
0.6
0.1
-0.2
-0.8
3.2
2.8
0.9
0.1
0.7
-0.6
2.6
-0.2
0.5
-0.7
-0.1
-1.4
2.7
1.3
-0.2
-0.4
2.5
1.4
0.2
-0.3
0.8
-0.2
2.7
1.3
2.1
-0.4
47 Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 21762 0 4.1 4.8
1.4
1.6
1.3
0.6
1.4
4.1
1.1
1.1
3.1
1.1
-0.5
2.1
-1.1
1.1
1.6
1.7
-2.0
1.2
0.0
2.5
-0.8
2.9
-0.9
-1.3
48 4833439L19Rik RIKEN cDNA 4833439L19 gene 97820 0 4.1 2.3
2.8
-1.4
-0.2
1.4
0.1
1.5
-0.6
-0.7
0.3
-1.8
1.2
0.5
-0.4
0.3
1.9
0.2
0.1
2.0
-1.0
0.6




49 Pwp1 PWP1 homolog, endonuclein 103136 0 4.0 3.8
2.0
1.5
-0.6
0.0
0.5
0.9
-0.3
1.6
2.6
1.0
1.5
-0.1
-0.4
1.0
0.6
1.5
-0.5
3.0
-1.1
0.9
-0.1
1.6
2.1
2.6
50 Rcan1 regulator of calcineurin 1 54720 0 4.0 3.2
2.3
0.6
0.2
1.7
0.1
2.2
1.3
1.0
1.0
3.3
1.2
0.3
0.3
0.7
-0.4
1.4
-0.1
0.4
-0.4
0.5
-0.7
0.2
-0.5
-0.0
-0.3
2.6
-0.4
0.1
0.1
0.9
0.2
0.4
-0.2
2.1
1.5
0.9
0.2
0.6
-0.1
-0.5
4.0
0.4
0.5
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