Orthologous genes in OrthoFinder**

Species Gene Description
 mmu-u.4   Isl2   insulin related protein 2 (islet 2) 
 mmu-r.6   Isl2   insulin related protein 2 (islet 2) 
 mmu-m.5   Isl2   insulin related protein 2 (islet 2) 
 mmu-u.4   Isl1   ISL1 transcription factor, LIM/homeodomain 
 rno-u.3   Lmo1   LIM domain only 1 
 rno-u.3   Isl2   ISL LIM homeobox 2 
 rno-u.3   Isl1   ISL LIM homeobox 1 
 hsa-u.4   ISL2   ISL LIM homeobox 2 
 hsa-u.4   ISL1   ISL LIM homeobox 1 
 gga-u.3   ISL2   ISL LIM homeobox 2 
 gga-u.3   ISL1   ISL LIM homeobox 1 
 dre-u.3   isl2b   ISL LIM homeobox 2b 
 dre-u.3   isl2a   ISL LIM homeobox 2a 
 dme-u.3   tup   tailup 
 cel-u.3   mec-3   Mechanosensory protein 3 
 cel-u.3   lim-7   LIM/homeobox protein lim-7 

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Top 50 coexpressed genes to Isl2 (mmu-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 mmu4725   Cholinergic synapse  4 107 3.56
 mmu4550   Signaling pathways regulating pluripotency of stem cells  3 127 2.21
 mmu4950   Maturity onset diabetes of the young  2 20 2.81
 mmu5207   Chemical carcinogenesis - receptor activation  3 225 -
 mmu4080   Neuroactive ligand-receptor interaction  3 376 -

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mmu:Isl2 (insulin related protein 2 (islet 2)) External Links;


Show/Hide Columns:          
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

mmu-u.4
for
Isl2
mmu-r.6
for
Isl2
mmu-m.5
for
Isl2
mmu-u.4
for
Isl1
rno-u.3
for
Lmo1
rno-u.3
for
Isl2
rno-u.3
for
Isl1
hsa-u.4
for
ISL2
hsa-u.4
for
ISL1
gga-u.3
for
ISL2
gga-u.3
for
ISL1
dre-u.3
for
isl2b
dre-u.3
for
isl2a
dme-u.3
for
tup
cel-u.3
for
mec-3
cel-u.3
for
lim-7
1 Nkx2-5 NK2 homeobox 5 18091 0 4.9 3.9
 2.8
 1.2
 -0.0
 0.8
 0.7

2.5
 2.6
 0.9
0.2
 3.3
1.5


2 Isl1 ISL1 transcription factor, LIM/homeodomain 16392 0 4.7 5.4
 1.7
 4.7
 1.9
0.3
 2.3
1.9
 2.3
0.3
 2.8
 2.8
 4.3
 4.3
 8.8
8.2
 8.2
7.1
0.4
 0.4
3 Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 19289 0 4.6 2.1
 3.5
 1.8
 0.6
 -0.1
 -0.6
 1.5
 0.9
 0.5
 0.6
 0.8
 2.0


4 Pitx1 paired-like homeodomain transcription factor 1 18740 0 4.6 4.3
 2.2
 4.9
4.6
 1.7
0.7
 1.4
-0.4
 2.7
0.6
 4.9
2.8
 4.5
2.5
 0.6
0.4
 3.5
1.8
 3.5
3.0
 5.1
4.0
 3.3
 1.9
 2.1
5 Pou4f1 POU domain, class 4, transcription factor 1 18996 0 4.5 5.5
 1.4
 2.9
 1.1
 4.1
 2.8
 4.5
 2.2
 2.0
1.5
 2.3
1.5
 6.5
5.7
 4.9
3.5
 1.1
 2.1
 2.9
6 Foxd3 forkhead box D3 15221 0 4.4 2.6
 3.0
 3.4
1.4
 1.9
1.8
 1.9
1.7
 1.3
1.2
 3.7
3.7
 3.6
2.7
 2.5
1.7
 2.9
2.1
 4.3
3.8
 3.3
2.7
 5.1
3.8
 1.8
1.5
 2.7
2.4
7 Phox2b paired-like homeobox 2b 18935 0 4.4 4.8
 1.8
 4.3
 0.7
 2.2
 1.5
 3.0
1.3
 3.5
2.1

2.7
2.6
 5.0
2.9
1.8
 2.0
8 Gfra3 glial cell line derived neurotrophic factor family receptor alpha 3 14587 0 4.3 2.9
 2.7
 3.6
 -1.2
 1.0
 0.6
 1.6
 1.1
 -0.8
 0.2
 2.1
0.1
 1.1
-0.2
-0.1
 1.1
9 Nkx2-3 NK2 homeobox 3 18089 0 4.2 3.5
 2.3
 3.2




2.5
 0.5
 3.6
 4.9


10 Chrnb4 cholinergic receptor, nicotinic, beta polypeptide 4 108015 0 4.2 2.4
 2.9
 2.5
0.6
 0.8
-0.1
 4.0
3.2
 3.5
1.7
 0.7
 0.3
 0.6
0.4
 1.8
0.0
 2.9
0.4
 2.2
0.8


11 Chrna3 cholinergic receptor, nicotinic, alpha polypeptide 3 110834 0 4.1 3.8
 2.0
 4.8
1.7
 0.4
0.2
 3.1
2.7
 3.7
1.6
 2.1
0.9
 2.5
0.1
 -0.6
-0.9
 0.8
0.7
 3.0
1.9
 3.7
1.6
 0.9
0.2
 2.7
1.6
 1.0
0.8
12 Shox2 short stature homeobox 2 20429 0 4.1 5.2
 1.2
 3.2
 1.6
 2.1
 2.5
 3.1
 1.7
 1.0
-0.2
 3.5
1.2
 4.0
2.4
 3.1
2.3
 4.5
4.1
 1.5
1.4
 2.0
1.7
13 Chrna6 cholinergic receptor, nicotinic, alpha polypeptide 6 11440 0 4.1 2.8
 2.6
 4.8
1.7
 0.4
0.2
 3.1
2.7
 3.7
1.6
 2.1
0.9
 2.5
0.1
 -0.6
-0.9
 0.8
0.7
 3.0
1.9
 3.7
1.6
 0.9
0.2
 2.7
1.6
 1.0
0.8
14 Vsx2 visual system homeobox 2 12677 0 4.0 3.7
 2.0
 1.9
 0.3
 0.1
 0.0
 0.9
 1.2
 1.3
0.8
 1.8
1.6
 5.8
2.3
 3.5
1.5
 2.6
 -0.3
 3.0
15 Grid2ip glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1 170935 0 4.0 1.1
 3.4
 0.4
 -1.2
 -0.3
 1.9

-1.4
 -1.0
 0.1
-1.7
 -0.9
-1.1


16 Sox3 SRY (sex determining region Y)-box 3 20675 0 3.9 2.1
 2.8
 2.9
2.7
 1.8
1.8
 1.9
1.2
 2.1
2.0
 3.5
1.6
 1.9
1.5
 0.8
0.5
 1.8
1.3
 3.0
2.7
 2.8
2.5
 5.4
5.0
 2.1
2.0
 4.8
1.3
17 Hoxd13 homeobox D13 15433 0 3.9 4.3
 1.5
 2.8




0.8
 0.6




18 Pax3 paired box 3 18505 0 3.9 4.2
 1.5
 1.5


0.8
 1.8
 0.1
-0.7
 0.4
-0.1
 0.1
-0.7
 -0.3
-1.2
 1.8
 -0.2
 -0.0
19 Slc10a4 solute carrier family 10 (sodium/bile acid cotransporter family), member 4 231290 0 3.8 3.8
7.4
 2.0
 -0.0
 3.7
 2.7
 1.7
 0.9
 0.9
 -0.3
 1.4


20 Zar1 zygote arrest 1 317755 0 3.8 3.0
 2.1
 2.9




1.8
1.1
 0.8
-0.9
 -0.2
-1.6
 0.6
-0.0


21 Six1 sine oculis-related homeobox 1 20471 0 3.8 4.3
 1.4
 2.6
 -0.0
 1.3
 2.1
 3.0
1.1
 2.7
2.2
 2.0
1.2
 3.9
2.3
 3.8
2.6
 5.6
4.3
 3.4
 0.5
 0.3
22 Ebf3 early B cell factor 3 13593 0 3.7 3.9
 1.6
 3.5
3.0
 1.6
1.0
 2.5
1.5
 2.0
1.1
 2.1
1.3
 2.7
1.9
 2.7
2.2
 3.5
1.5
 2.8
2.4
 3.0
1.8
 5.8
 2.0
 1.8
23 Onecut1 one cut domain, family member 1 15379 0 3.7 4.0
 1.5
 2.1
 0.9
0.8
 1.4
0.5
 1.8
0.2
 2.9
1.4
 3.7
2.6
 1.8
1.4
 0.7
0.4
 1.9
1.1
 1.8
1.0
 2.0
 2.1
0.1
 4.0
1.7
24 Hoxc9 homeobox C9 15427 0 3.7 2.3
 2.4
 2.2
2.2
 1.6
1.2
 1.4
0.5
 1.7
1.3
 3.3
3.2
 3.4
1.9
 1.1
0.7
 0.9
0.6
 3.2
2.2
 3.9
3.4
 1.8
 2.0
 1.7
25 Dbh dopamine beta hydroxylase 13166 0 3.6 2.1
 2.5
 1.5
 0.2
 1.6
 0.0
 -0.2
 -0.1
 0.1
 1.7
 1.9
 2.6
 0.3
 0.3
 2.2
26 Crybb2 crystallin, beta B2 12961 0 3.6 3.1
 1.9
 0.9
 -0.5
 3.9
 1.2

-0.4
 -1.0
 0.2
 -0.1


27 Scrt1 scratch family zinc finger 1 170729 0 3.5 1.6
 2.6
 1.5
0.8
 0.9
0.6
 1.8
0.9
 1.3
0.8
 3.0
1.6
 0.7
-0.0
 1.3
 -0.3
 5.6
3.3
 3.9
2.8
 1.5
0.8
 0.5
 1.4
28 Hoxb13 homeobox B13 15408 0 3.5 3.5
 1.5
 1.8
 1.2
 2.8
 1.1
 3.7
 4.8

-1.5
 -0.1


29 Nobox NOBOX oogenesis homeobox 18291 0 3.5 2.4
 2.1
 0.1




0.3
 0.6




30 Neurog2 neurogenin 2 11924 0 3.4 3.1
 1.7
 0.0
 1.9
 -0.5
 -1.0
 2.9
 1.2

1.4
 2.6
 2.7
 -0.2
 1.5
31 Rho rhodopsin 212541 0 3.4 2.2
 2.1
 -0.0
 1.4
 3.0
 0.8
 0.1
 0.2
 0.8
0.7
 1.4
0.5
 2.2
1.6
 1.9
0.6


32 Glis1 GLIS family zinc finger 1 230587 0 3.3 3.0
 1.7
 0.7




-1.0
 1.4

1.3

33 Dll3 delta like canonical Notch ligand 3 13389 0 3.3 2.6
 1.9
 2.7


3.7
 0.8






34 Nrn1l neuritin 1-like 234700 0 3.3 2.6
 1.9
 1.0
 1.4
 1.8
 1.2

0.0
 -0.6
 1.4
1.1
 1.2
1.0


35 Amh anti-Mullerian hormone 11705 0 3.3 1.5
 2.5
 -0.5
 0.4
 3.4
 -1.3
 2.2
 -0.4
 1.6
 -1.0
 -1.1
 0.5


36 Hand1 heart and neural crest derivatives expressed 1 15110 0 3.3 4.2
 0.9
 3.2
2.5
 0.6
-1.1
 1.8
1.7
 2.4
1.2
 3.1
2.3
 5.6
4.3
 1.1
0.1
 2.7
0.8
 2.7
 5.0
 2.6

37 Gm16551 predicted gene 16551 100503019 0 3.3 3.3













38 Slc18a3 solute carrier family 18 (vesicular monoamine), member 3 20508 0 3.3 2.9
 1.7
 5.0
2.0
 0.4
0.1
 1.2
0.7
 4.6
2.7
 -0.3
 -0.1
 1.7
1.0
 3.1
1.8
 5.1
0.9
 3.6
1.2
 0.7
0.4
 0.5
-0.3
 3.2
0.1
39 Msx1 msh homeobox 1 17701 0 3.3 2.4
 1.9
 0.8
0.4
 2.3
0.9
 0.3
-0.1
 0.5
-0.9
 2.4
1.2
 2.3
2.2
 1.4
0.6
 1.4
0.4
 1.4
1.0
 2.9
2.5
 5.0
 1.7
 1.5
40 Pax2 paired box 2 18504 0 3.2 3.3
-0.3
-0.5
 -0.9
 0.3
 -1.5
 0.7
 0.3
 0.9
0.8
 1.6
-0.5
 2.2
1.3
 6.3
1.7
0.3
 0.8
41 Hand2 heart and neural crest derivatives expressed 2 15111 0 3.2 2.8
 1.7
 3.2
2.5
 0.6
-1.1
 1.8
1.7
 2.4
1.2
 3.1
2.3
 5.6
4.3
 1.1
0.1
 2.7
0.8
 2.7
 5.0
 2.6

42 Scn5a sodium channel, voltage-gated, type V, alpha 20271 0 3.2 1.7
 2.3
 5.6
3.4
 1.0
0.5
 4.2
3.3
 3.6
2.6
 1.3
0.5
 0.6
0.4
 1.3
0.5
 1.4
1.1
 1.6
0.7
 1.1
1.0
 -0.5

43 Atp8b3 ATPase, class I, type 8B, member 3 67331 0 3.2 2.5
 1.8
 1.0
0.6
 0.9
0.5
 1.2
0.6
 1.1
0.9
 0.2
0.1
 0.8
0.6
 1.4
0.8
 2.1
0.9
 1.3
0.8
 0.9
0.4
 0.3
0.0
 0.4
-0.1
 1.8
0.7
44 Gpr3 G-protein coupled receptor 3 14748 0 3.2 1.6
 2.4
 0.2
 0.1
 1.3
 -0.4
 2.7
 -0.1






45 Irx5 Iroquois homeobox 5 54352 0 3.2 4.2
 0.8
 0.7
 -0.1
 1.2
 1.1
 2.3
 0.7
 1.3
 0.4
 1.7
 3.7


46 Pdx1 pancreatic and duodenal homeobox 1 18609 0 3.2 2.7
 1.7
 2.4
 0.7
 2.2
 2.8



0.5
 0.9


47 Celf3 CUGBP, Elav-like family member 3 78784 0 3.2 1.0
 2.7
 4.0
3.1
 2.9
1.3
 1.5
0.7
 2.1
1.3
 1.6
0.3
 1.2
-0.3
 1.1
1.0
 3.0
2.1
 3.4
2.3
 2.7
2.3
 1.3
 0.5
 1.8
48 Hotairm1 Hoxa transcript antisense RNA, myeloid-specific 1 105242658 0 3.1 3.2













49 H1f8 H1.8 linker histone 171506 0 3.1 2.4
 1.8
 -0.3


-0.4
 0.4
 0.2
 -0.0
 -0.6
 0.3


50 Draxin dorsal inhibitory axon guidance protein 70433 0 3.1 2.0
 2.0
 1.7
 0.3
 -0.1
 -1.2

0.8
 1.2
 0.5
 1.0


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