Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4   TLR7   toll like receptor 7 
 hsa-r.6   TLR7   toll like receptor 7 
 hsa-m.7   TLR7   toll like receptor 7 
 hsa-m2.4   TLR7   toll like receptor 7 
 mcc-u.3   TLR7   toll like receptor 7 
 mmu-u.4   Tlr7   toll-like receptor 7 
 rno-u.3   Tlr7   toll-like receptor 7 
 gga-u.3   TLR7   toll like receptor 7 

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Top 50 coexpressed genes to TLR7 (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa5322   Systemic lupus erythematosus  6 109 6.06
 hsa5150   Staphylococcus aureus infection  5 68 5.75
 hsa4662   B cell receptor signaling pathway  5 74 5.56
 hsa4380   Osteoclast differentiation  5 115 4.62
 hsa5171   Coronavirus disease - COVID-19  5 205 3.44

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hsa:TLR7 (toll like receptor 7) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-u.4
for
TLR7
hsa-r.6
for
TLR7
hsa-m.7
for
TLR7
hsa-m2.4
for
TLR7
mcc-u.3
for
TLR7
mmu-u.4
for
Tlr7
rno-u.3
for
Tlr7
gga-u.3
for
TLR7
1 LY86 lymphocyte antigen 86 9450 0 10.2 9.3
 5.4
 8.7
 1.7
 7.9
 5.8
 2.3
2 MPEG1 macrophage expressed 1 219972 1 9.7 8.5
 4.7
 8.4
 3.6
 8.2
 5.7
 5.3
3 CD180 CD180 molecule 4064 6 9.6 8.0
 4.6
 8.9
 4.0
 7.0
 6.7
 3.5
4 MS4A7 membrane spanning 4-domains A7 58475 0 9.1 7.1
 4.2
 8.8
 1.2
 6.3
 3.9
5 TASL TLR adaptor interacting with endolysosomal SLC15A4 80231 5 9.0 8.1
 3.1
 7.8
 3.5
 7.4
 5.2
 6.1
6 MS4A6A membrane spanning 4-domains A6A 64231 0 8.7 6.3
 4.8
 9.1
 1.7
 7.7
7.2
 9.4
9.0
7 FGD2 FYVE, RhoGEF and PH domain containing 2 221472 0 8.6 6.7
 5.0
 8.4
 1.2
1.2
 4.0
1.7
 1.0
 -0.0
8 CYBB cytochrome b-245 beta chain 1536 9 8.5 7.5
 4.9
 7.5
 2.9
0.4
 6.8
0.4
 8.4
-0.2
 4.8
0.3
9 TLR8 toll like receptor 8 51311 92 8.2 10.0
 3.9
 4.4
 2.6
 7.5
 8.3
10 GAPT GRB2 binding adaptor protein, transmembrane 202309 1 8.2 6.5
 3.7
 7.8
 1.1
 1.2
 2.5
11 CD86 CD86 molecule 942 18 8.0 7.0
 4.0
 7.0
 3.2
 10.2
 6.2
 2.7
12 CX3CR1 C-X3-C motif chemokine receptor 1 1524 4 7.5 6.4
 3.9
 6.8
 2.6
 3.9
 4.2
 4.1
13 RNASE6 ribonuclease A family member k6 6039 0 7.4 6.1
 3.6
 6.8
 1.3
 2.6

14 LILRB1 leukocyte immunoglobulin like receptor B1 10859 2 7.3 6.9
 3.9
 5.9
 2.8
2.3
 5.3
5.3
 4.6
4.5
15 SCIMP SLP adaptor and CSK interacting membrane protein 388325 0 7.3 4.8
 1.5
 8.0
 2.3
 2.1
 2.5
16 IRF8 interferon regulatory factor 8 3394 8 7.2 6.1
 3.5
 6.7
 2.9
 2.9
 3.4
 1.2
17 LILRB4 leukocyte immunoglobulin like receptor B4 11006 1 7.0 6.8
 3.6
 5.6
 2.8
2.3
 5.3
5.3
 4.6
4.5
18 FOLR2 folate receptor beta 2350 0 7.0 6.4
 2.5
 5.9
 1.3
0.7
 3.3
-0.1
 4.2
0.2
 -0.7
-0.9
19 CSF1R colony stimulating factor 1 receptor 1436 1 6.9 5.9
 3.0
 6.2
 2.4
 7.2
 7.9
 5.5
20 TFEC transcription factor EC 22797 0 6.8 5.8
 3.3
 6.1
 2.3
1.1
 2.8
2.0
 4.6
1.1
 3.1
1.7
21 GPR34 G protein-coupled receptor 34 2857 0 6.8 5.4
 4.1
 6.5
 0.7
 5.5
 5.5
 5.9
22 MS4A4A membrane spanning 4-domains A4A 51338 1 6.8 6.0
 3.6
 5.9
 1.8
0.8
 7.4
5.5
 4.4
23 BTK Bruton tyrosine kinase 695 13 6.8 5.8
 3.6
 6.1
 2.1
 4.8
 7.0
 3.9
24 HLA-DMB major histocompatibility complex, class II, DM beta 3109 1 6.7 4.6
 2.1
 7.2
 1.7
 1.7
0.2
 3.7
 1.4
0.4
25 TLR10 toll like receptor 10 81793 33 6.5 6.0
 2.5
 5.3
 2.7
2.6
 5.0
4.8
 5.7
5.2
 7.1
4.1
26 ADAP2 ArfGAP with dual PH domains 2 55803 0 6.4 4.9
 3.9
 6.3
 1.5
 4.7
 2.7
 3.8
27 C1QC complement C1q C chain 714 1 6.3 4.8
 2.9
 6.2
 0.8
 6.0
 6.1
 4.0
28 NAPSB napsin B aspartic peptidase, pseudogene 256236 0 6.3 5.6
 4.1
 5.5



29 MARCHF1 membrane associated ring-CH-type finger 1 55016 1 6.1 3.8
 4.2
 7.0
 1.9
 6.4
 4.7
 1.6
30 MNDA myeloid cell nuclear differentiation antigen 4332 1 6.1 5.8
 2.9
 4.9
 3.2
2.4
 7.4
4.1
 4.1
31 CCR2 C-C motif chemokine receptor 2 729230 3 6.1 5.8
 3.8
 4.9
 3.1
1.8
 5.3
3.2
 9.7
4.5
 4.4
3.9
32 MS4A14 membrane spanning 4-domains A14 84689 0 6.1 6.1
 3.1
3.4
 4.4
 1.2
33 PLD4 phospholipase D family member 4 122618 0 6.0 5.0
 3.5
 5.6
 2.8
 7.5
 7.3
 4.3
34 MILR1 mast cell immunoglobulin like receptor 1 284021 0 5.9 5.4
 3.2
 4.9
 3.7
 5.7
2.7
35 SIGLEC1 sialic acid binding Ig like lectin 1 6614 4 5.8 5.0
 4.4
 5.3
 2.6
 5.5
 4.7
 3.7
36 CYSLTR1 cysteinyl leukotriene receptor 1 10800 0 5.8 5.3
 3.8
 4.8
 2.3
 3.8
1.1
37 MSR1 macrophage scavenger receptor 1 4481 2 5.7 5.3
 3.9
 4.7
 1.1
 5.1
 4.5
38 BLNK B cell linker 29760 8 5.7 4.9
 2.9
 5.0
 2.4
 3.7
 3.6
 4.7
39 C1QB complement C1q B chain 713 0 5.6 4.4
 2.9
 5.4
 1.1
 6.0
 6.2
 4.0
40 LINC02812 long intergenic non-protein coding RNA 2812 107984957 0 5.6 5.6





41 P2RY13 purinergic receptor P2Y13 53829 0 5.5 4.4
 2.9
 5.3
 4.9
 7.8
 6.8
 2.5
42 C1QA complement C1q A chain 712 3 5.5 4.9
 3.2
 4.7
 0.9
 5.5
 6.2
 4.1
43 P2RY12 purinergic receptor P2Y12 64805 0 5.5 4.9
 4.1
 4.7
 2.2
 6.8
 5.6
 2.0
44 PTPRO protein tyrosine phosphatase receptor type O 5800 0 5.4 4.4
 1.8
 5.1
 2.1
 4.2
 4.3
 0.8
45 ADORA3 adenosine A3 receptor 140 0 5.4 4.5
 2.4
 4.9
 2.7
1.3
 0.6
0.5
 0.3
0.2
 1.2
1.1
46 CIITA class II major histocompatibility complex transactivator 4261 0 5.3 3.2
 1.7
 6.2
 0.5
 0.7
 1.9
 1.9
47 DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 1 27071 0 5.3 4.0
 2.3
 5.4
 2.2
 0.9
 2.6
 2.4
48 VSIG4 V-set and immunoglobulin domain containing 4 11326 0 5.3 4.6
 2.8
 4.6
 0.7
 3.2
 2.2
49 CLEC10A C-type lectin domain containing 10A 10462 0 5.2 3.9
 2.1
 5.2
 2.2
1.1
 6.5
5.9
 8.4
7.8
 3.4
1.9
50 HLA-DOA major histocompatibility complex, class II, DO alpha 3111 0 5.2 3.7
 2.5
 5.5
 1.5
1.3
 2.0
0.4
 1.7
1.4
 2.0
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