Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4   ISL1   ISL LIM homeobox 1 
 hsa-r.6   ISL1   ISL LIM homeobox 1 
 hsa-m.7   ISL1   ISL LIM homeobox 1 
 hsa-m2.4   ISL1   ISL LIM homeobox 1 
 hsa-u.4   ISL2   ISL LIM homeobox 2 
 mmu-u.4   Isl2   insulin related protein 2 (islet 2) 
 mmu-u.4   Isl1   ISL1 transcription factor, LIM/homeodomain 
 rno-u.3   Lmo1   LIM domain only 1 
 rno-u.3   Isl2   ISL LIM homeobox 2 
 rno-u.3   Isl1   ISL LIM homeobox 1 
 gga-u.3   ISL2   ISL LIM homeobox 2 
 gga-u.3   ISL1   ISL LIM homeobox 1 
 dre-u.3   isl2b   ISL LIM homeobox 2b 
 dre-u.3   isl2a   ISL LIM homeobox 2a 
 dme-u.3   tup   tailup 
 cel-u.3   mec-3   Mechanosensory protein 3 
 cel-u.3   lim-7   LIM/homeobox protein lim-7 

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Top 50 coexpressed genes to ISL1 (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa4550   Signaling pathways regulating pluripotency of stem cells  4 121 3.33
 hsa5202   Transcriptional misregulation in cancer  3 192 -
 hsa5165   Human papillomavirus infection  2 331 -
 hsa4080   Neuroactive ligand-receptor interaction  3 353 -
 hsa5200   Pathways in cancer  2 531 -

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hsa:ISL1 (ISL LIM homeobox 1) External Links;


Show/Hide Columns:          
Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-u.4
for
ISL1
hsa-r.6
for
ISL1
hsa-m.7
for
ISL1
hsa-m2.4
for
ISL1
hsa-u.4
for
ISL2
mmu-u.4
for
Isl2
mmu-u.4
for
Isl1
rno-u.3
for
Lmo1
rno-u.3
for
Isl2
rno-u.3
for
Isl1
gga-u.3
for
ISL2
gga-u.3
for
ISL1
dre-u.3
for
isl2b
dre-u.3
for
isl2a
dme-u.3
for
tup
cel-u.3
for
mec-3
cel-u.3
for
lim-7
1 ISL1-DT ISL1 divergent transcript 642366 1 29.1 29.4














2 HAND1 heart and neural crest derivatives expressed 1 9421 0 5.6 4.4
 1.8
 5.5
 3.1
2.3
 3.3
3.2
 3.2
2.5
 0.6
-1.1
 1.8
1.7
 2.4
1.2
 1.1
0.1
 2.7
0.8
 2.7
 5.0
 2.6

3 SP8 Sp8 transcription factor 221833 0 5.0 4.2
 2.4
 4.7
 2.1
1.5
 2.1
1.7
 4.3
3.4
 0.0
 -0.7
 2.0
 0.1
 0.8
 0.6
0.1
 1.3
0.7
 1.1
 0.5
 2.9
4 HOXB13 homeobox B13 10481 0 4.8 4.0
 0.3
 4.5
 3.7
 3.5
 1.8
 1.2
 2.8
 1.1

-1.5
 -0.1


5 EYA1 EYA transcriptional coactivator and phosphatase 1 2138 0 4.6 4.5
 2.8
 3.5
 0.7
0.1
 2.3
1.2
 2.5
2.4
 1.7
0.4
 0.4
0.3
 1.4
0.8
 0.8
0.6
 2.5
1.9
 2.1
1.4
 3.2
2.3
 3.1
 -0.7
 2.8
6 PITX2 paired like homeodomain 2 5308 0 4.5 4.6
 1.2
 3.3
 4.9
2.8
 4.6
2.1
 4.9
4.6
 1.7
0.7
 1.4
-0.4
 2.7
0.6
 0.6
0.4
 3.5
1.8
 3.5
3.0
 5.1
4.0
 3.3
 1.9
 2.1
7 RFX6 regulatory factor X6 222546 0 4.5 4.8
 3.7
 3.0
 2.0
1.1
 0.4
-0.1
 0.4
-0.1
 1.8
0.6
 1.2
-0.1
 0.3
0.2
 0.4
-0.0
 1.9
1.3
 1.8
0.3
 1.6
0.8
 -1.0
 0.4
 2.0
8 HAND2 heart and neural crest derivatives expressed 2 9464 0 4.3 4.9
 0.6
 2.6
 3.1
2.3
 3.3
3.2
 3.2
2.5
 0.6
-1.1
 1.8
1.7
 2.4
1.2
 1.1
0.1
 2.7
0.8
 2.7
 5.0
 2.6

9 SLITRK6 SLIT and NTRK like family member 6 84189 0 4.2 4.7
 2.3
 2.7
 -0.5
 0.2
 3.9
 -0.1
 -0.3
 2.0
 -0.4
 0.9
 2.8
 2.3


10 DLX6 distal-less homeobox 6 1750 0 4.2 4.7
 2.2
 2.6
 3.6
3.5
 1.8
0.0
 4.5
2.3
 0.7
0.5
 0.1
-0.2
 2.8
1.8
 0.5
-0.3
 1.7
0.9
 2.7
2.6
 3.2
2.3
 4.6
 0.4
 2.0
11 MEIS2 Meis homeobox 2 4212 0 4.0 4.2
 1.9
 2.9
 1.2
1.2
 2.1
2.0
 5.7
3.8
 1.1
0.6
 1.2
0.3
 2.2
1.3
 0.3
-0.3
 2.0
0.3
 4.8
4.1
 5.8
3.6
 4.6
 1.5
 2.4
12 SST somatostatin 6750 0 4.0 5.1
 1.0
 2.0
 1.1
 2.1
 4.3
 0.8
 1.0
 1.1
 0.8
 3.5
 1.2
 0.4


13 CDH12 cadherin 12 1010 0 4.0 4.2
 2.0
 2.9
 -0.1
 1.2
 1.1
 -0.0
 0.3
 0.0

1.3
 1.8


14 DLX5 distal-less homeobox 5 1749 0 3.9 4.7
 1.8
 2.2
 0.6
 0.9
 4.5
 0.8
 -0.7
 3.2
 -0.4
 2.6
 1.0
 2.6
 3.0
 0.7
 2.1
15 PCDH7 protocadherin 7 5099 0 3.9 3.5
 1.2
 3.4
 -0.3
 -0.3
 0.7
 -0.6
 -0.3
 0.2
 -1.1
 -0.2
 1.0
 0.4


16 FEV FEV transcription factor, ETS family member 54738 0 3.9 3.5
 2.0
 3.3
 2.5




0.4
 1.2
 1.5
 0.9
 -0.7
 0.7
 1.4
17 PAX9 paired box 9 5083 0 3.8 3.2
 0.4
 3.4
 2.3
 2.6
1.5
 2.8
1.7
 0.2
 -0.1
 2.3
 -0.1
 1.6
 1.6
0.5
 4.1
2.5
 1.3
 0.3
 1.7
18 ONECUT3 one cut homeobox 3 390874 0 3.7 3.8
 -0.3
2.9
1.4
 3.7
 2.1
 0.9
0.8
 1.4
0.5
 1.8
0.2
 1.8
1.4
 0.7
0.4
 1.9
1.1
 1.8
1.0
 2.0
 2.1
0.1
 4.0
1.7
19 MEIS1 Meis homeobox 1 4211 0 3.7 3.4
 2.0
 3.1
 1.2
1.2
 2.1
2.0
 5.7
3.8
 1.1
0.6
 1.2
0.3
 2.2
1.3
 0.3
-0.3
 2.0
0.3
 4.8
4.1
 5.8
3.6
 4.6
 1.5
 2.4
20 LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 0 3.6 3.4
 -0.4
 3.0
 -0.2
 0.3
 1.5
 2.3
 0.9
 2.2
 0.4
 2.7
 1.0
 -0.2


21 MIR7-3HG MIR7-3 host gene 284424 0 3.6 2.7
 0.4
 3.7












22 FOXG1 forkhead box G1 2290 0 3.6 2.7
 0.5
 3.7
 3.7
3.7
 4.4
3.0
 3.4
1.4
 1.9
1.8
 1.9
1.7
 1.3
1.2
 2.5
1.7
 2.9
2.1
 4.3
3.8
 3.3
2.7
 5.1
3.8
 1.8
1.5
 2.7
2.4
23 EPHA7 EPH receptor A7 2045 0 3.6 2.4
 2.3
 3.9
 0.8
0.8
 1.0
1.0
 1.5
1.1
 2.6
1.8
 2.1
1.8
 1.9
1.3
 1.6
1.0
 1.7
1.6
 1.6
1.0
 1.5
1.4
 0.4
 0.3
 0.9
24 FOXF2 forkhead box F2 2295 0 3.6 2.6
 1.5
 3.6
 3.4
2.1
 2.7
2.5
 1.8
1.7
 1.1
0.5
 1.2
1.0
 1.3
0.8
 1.9
0.2
 2.2
2.2
 3.4
3.3
 3.3
3.1
0.4
 2.8
25 NKX2-1 NK2 homeobox 1 7080 0 3.6 3.6
 0.3
 2.6
 2.3
 1.7
 3.1
 -0.4
 -1.2
 3.7
 -0.2
 2.3
 0.6
0.3
 2.5
2.2
 4.2
 0.7
 2.6
26 SIX3 SIX homeobox 3 6496 0 3.5 2.3
 1.4
 3.9
 2.2
1.0
 2.4
 5.8
 0.7
 4.1
 3.5
 2.6
0.1
 2.4
1.2
 5.2
4.0
 4.1
3.6
 4.0
 -0.7
 6.9
27 PHOX2B paired like homeobox 2B 8929 0 3.5 3.8
 2.3
 2.3
 3.0
1.3
 4.4
 4.3
 0.7
 2.2
 1.5

2.7
2.6
 5.0
2.9
1.8
 2.0
28 SLC5A7 solute carrier family 5 member 7 60482 0 3.5 3.1
 1.9
 3.0
 -0.6
 0.5
 3.9
 -0.1
 1.5
 3.0
 0.5
 0.2
 -0.0
 0.3
0.9
 1.2
29 FAM83B family with sequence similarity 83 member B 222584 0 3.4 3.3
 0.5
 2.7
 -0.2
 -0.3
 0.7


-0.3
 -0.4
 0.2
 -0.6


30 HOXD9 homeobox D9 3235 0 3.4 3.3
 1.2
 2.7
 3.3
3.2
 3.7
2.4
 2.2
2.2
 1.6
1.2
 1.4
0.5
 1.7
1.3
 1.1
0.7
 0.9
0.6
 3.2
2.2
 3.9
3.4
 1.8
 2.0
 1.7
31 SERPINB5 serpin family B member 5 5268 0 3.4 2.9
 1.5
 3.0
 -0.4
 0.3
 0.6
 -0.1
 -0.1
 0.3
 -0.6
 -0.3




32 KCNV1 potassium voltage-gated channel modifier subfamily V member 1 27012 0 3.4 1.9
 1.2
 4.0
 0.1
 0.6
 0.9
 -1.1
 0.4
 0.8
 0.8
 0.5
 1.1
 0.4


33 ALX1 ALX homeobox 1 8092 0 3.3 4.5
 1.7
 1.3
 0.7




0.0
 3.7
 2.6
 2.3


34 HOXD11 homeobox D11 3237 0 3.3 3.5
 1.9
 2.3
 3.2
 2.4
 1.2


2.1
 1.0
 1.5
0.5
 2.9
1.0


35 HEY1 hes related family bHLH transcription factor with YRPW motif 1 23462 0 3.3 2.3
 1.1
 3.4
 1.6
0.1
 1.7
1.5
 2.7
2.0
 2.3
0.7
 0.9
0.1
 1.1
0.6
 1.7
-0.1
 1.6
1.4
 0.9
0.6
 2.8
2.1
 0.8

36 FLRT3 fibronectin leucine rich transmembrane protein 3 23767 0 3.3 3.1
 1.7
 2.6
 1.5
-0.4
 0.2
0.2
 1.7
1.4
 1.8
0.9
 0.0
-0.4
 1.3
0.1
 -0.6
-1.3
 0.2
-0.2
 1.7
1.0
 1.2
0.8
 -0.3
-0.3
 1.4
0.9
 2.1
1.2
37 LRFN5 leucine rich repeat and fibronectin type III domain containing 5 145581 0 3.3 3.5
 1.5
 2.3
 2.9
1.5
 1.7
0.7
 0.5
0.4
 2.8
0.8
 1.6
0.9
 2.0
-0.0
 2.7
0.5
 1.5
1.0
 2.6
1.8
 1.8
0.5
0.5
 -0.0
38 BNC1 basonuclin 1 646 0 3.2 3.4
 1.2
 2.3
 0.0
-0.5
 2.6
1.4
 4.0
2.1
 0.3
0.1
 1.3
1.0
 2.9
0.8
 0.8
0.4
 1.6
0.8
 1.3
0.1
 2.3
1.1
 3.9
2.8
 0.7
 -1.1
39 GRP gastrin releasing peptide 2922 0 3.2 2.3
 0.8
 3.3
 0.2
 -0.7
 -1.4
 -0.1
 -0.1
 -1.5
 0.6
 0.9
 0.4
 1.3


40 HOXA13 homeobox A13 3209 0 3.1 4.0
 2.9
 1.5
 4.2




1.5
 1.5
 1.2
0.2
 2.2
0.8


41 KRT9 keratin 9 3857 0 3.1 2.2
 0.7
 3.3
 0.6
0.3
 1.8
1.2
 2.0
1.9
 1.4
1.2
 2.1
1.1
 2.9
1.5
 1.2
0.8
 0.9
0.8
 0.5
0.4
 0.6
0.5


42 CYP27C1 cytochrome P450 family 27 subfamily C member 1 339761 0 3.1 2.5
 1.3
 3.0
 2.0
0.3
 0.1
 -0.3
 -2.0
 -0.1
 -1.5
 -1.2
-1.2
 0.7
-0.4
 -0.6
-1.1
 -0.8
-1.2


43 GRIK2 glutamate ionotropic receptor kainate type subunit 2 2898 0 3.1 2.6
 2.0
 2.8
 0.1
-0.2
 0.4
-0.5
 1.7
0.9
 1.6
-0.1
 1.8
1.0
 1.4
0.5
 0.6
-0.2
 1.1
0.8
 2.1
0.6
 0.6
-0.0
 1.8
1.5
 1.9
0.6
 1.5
1.3
44 PRSS12 serine protease 12 8492 0 3.1 3.3
 1.9
 2.2
 -0.3
 -0.6
 0.1
 0.9
 -0.2
 1.7
 -0.4
-0.5
 0.8
0.3
 0.6
0.1
 0.4
-0.4
 -0.2

45 BARX2 BARX homeobox 2 8538 0 3.1 2.0
 0.3
 3.4
 2.1
 0.6
 0.6
 0.6
 -0.4
 -0.5
 -0.8
 0.3
 0.1
 0.7


46 COL4A6 collagen type IV alpha 6 chain 1288 0 3.1 2.0
 1.8
 3.4
 0.1
-0.3
 0.9
0.6
 0.9
-0.3
 0.2
-0.2
 0.5
0.3
 0.8
0.1
 -0.7
-0.9
 1.0
0.0
 1.8
1.3
 1.2
0.8
 -0.5
-0.8
 -0.3
-0.5
 0.9
0.6
47 ASXL3 ASXL transcriptional regulator 3 80816 0 3.1 2.6
 2.3
 2.7
 -0.2
 0.2
 1.7


-0.1
 -0.3




48 TBX3 T-box transcription factor 3 6926 0 3.1 3.4
 1.0
 2.0
 0.8
 0.8
 1.6
 -0.3
 0.9
 2.2
 -0.4
 -0.6
 3.3
 6.2


49 DLX6-AS1 DLX6 antisense RNA 1 285987 0















50 PRPH peripherin 5630 0 3.0 2.4
 1.2
 3.0












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