Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-u.4   DNASE2   deoxyribonuclease 2, lysosomal 
 hsa-r.6   DNASE2   deoxyribonuclease 2, lysosomal 
 hsa-m.7   DNASE2   deoxyribonuclease 2, lysosomal 
 hsa-m2.4   DNASE2   deoxyribonuclease 2, lysosomal 
 mcc-u.3   DNASE2   deoxyribonuclease 2, lysosomal 
 mmu-u.4   Dnase2a   deoxyribonuclease II alpha 
 rno-u.3   Dnase2   deoxyribonuclease 2, lysosomal 
 cfa-u.3   DNASE2   deoxyribonuclease 2, lysosomal 
 dre-u.3   dnase2   deoxyribonuclease II, lysosomal 
 dme-u.3   DNaseII   Deoxyribonuclease II 
 cel-u.3   crn-7   Cell-death-related nuclease 7 
 cel-u.3   nuc-1   Deoxyribonuclease-2 

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Top 50 coexpressed genes to DNASE2 (hsa-u.4 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa4142   Lysosome  24 124 7.09
 hsa511   Other glycan degradation  8 15 7.02
 hsa4141   Protein processing in endoplasmic reticulum  6 159 5.11
 hsa531   Glycosaminoglycan degradation  5 16 6.89
 hsa600   Sphingolipid metabolism  5 39 6.97

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hsa:DNASE2 (deoxyribonuclease 2, lysosomal) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-u.4
for
DNASE2
hsa-r.6
for
DNASE2
hsa-m.7
for
DNASE2
hsa-m2.4
for
DNASE2
mcc-u.3
for
DNASE2
mmu-u.4
for
Dnase2a
rno-u.3
for
Dnase2
cfa-u.3
for
DNASE2
dre-u.3
for
dnase2
dme-u.3
for
DNaseII
cel-u.3
for
crn-7
cel-u.3
for
nuc-1
1 HEXB hexosaminidase subunit beta 3074 0 7.0 7.2
 2.3
 5.1
 3.7
3.5
 3.6
2.2
 4.6
2.1
 5.2
4.2
 0.6
-0.1
 1.1
0.6
 1.4
 3.1
2 PSAP prosaposin 5660 0 6.9 7.6
 2.9
 4.5
 1.7
 2.6
0.1
 3.8
 3.1
 1.9
 1.3
 1.8
-0.6
 5.7
2.5
3 GLB1 galactosidase beta 1 2720 1 6.7 6.9
 2.9
 4.8
 3.2
2.4
 2.5
1.3
 3.1
1.4
 2.3
2.2
 2.4
1.7
 3.3
1.2
 1.6
 0.5
4 ERP29 endoplasmic reticulum protein 29 10961 0 6.3 6.1
 2.9
 4.9
2.6
 2.7
 -0.1
0.8

5 MAN2B1 mannosidase alpha class 2B member 1 4125 0 6.2 6.3
 1.5
 4.6
 3.3
 3.2
 2.1
 6.0
 1.8
 3.1
1.0
 -0.0
 0.5
6 CTSD cathepsin D 1509 0 6.2 6.6
 2.6
 4.3
 4.7
0.7
 2.8
0.9
 5.8
0.6
 2.2
2.1
 2.6
0.7
 2.5
0.1
 1.1
1.0
 5.0
3.9
7 HEXA hexosaminidase subunit alpha 3073 0 6.1 6.5
 2.2
 4.2
 3.7
3.5
 3.6
2.2
 4.6
2.1
 5.2
4.2
 0.6
-0.1
 1.1
0.6
 1.4
 3.1
8 ATP6AP1 ATPase H+ transporting accessory protein 1 537 0 5.8 6.1
 1.9
 4.1
 2.9
 1.8
 2.8
 2.3
 1.9
0.5
 2.5
-1.1
 0.4
 0.1
9 FUCA1 alpha-L-fucosidase 1 2517 0 5.8 5.4
 1.6
 4.8
 2.5
1.2
 3.5
2.0
 4.5
1.9
 3.9
1.6
 2.5
1.5
2.1
 -0.7
10 GRN granulin precursor 2896 0 5.8 6.5
 2.3
 3.7
 2.0
 4.5
 4.8
 4.7
 3.0
1.5
-0.2
 4.7
11 GLMP glycosylated lysosomal membrane protein 112770 0 5.7 6.2
 1.5
 3.8
 3.6
 3.4
 4.1
 3.1
 1.6


12 BLVRB biliverdin reductase B 645 0 5.7 5.1
 1.8
 4.9
 4.1
 4.0
 2.2
 3.1
 0.6
 0.0

13 PLD3 phospholipase D family member 3 23646 0 5.6 6.1
 1.5
 3.7
 2.4
 2.8
 5.2
 2.5
 2.8
 -0.2
 0.6
0.2
 4.4
0.2
14 CRTAP cartilage associated protein 10491 0 5.5 5.5
 2.1
 4.3
 1.6
0.3
 2.4
0.5
 2.0
1.5
 0.8
0.5
 -0.1
-1.0
0.6
 -0.4
15 NUPR1 nuclear protein 1, transcriptional regulator 26471 0 5.4 4.7
 2.2
 4.9
 2.0
 0.6
 2.2
 1.6
 -0.5
 0.3

16 MANBA mannosidase beta 4126 0 5.4 6.2
 2.1
 3.3
 2.9
 3.5
 0.9
 1.8
 1.9
 0.2
 -1.0
 2.8
17 MAN1B1 mannosidase alpha class 1B member 1 11253 0 5.4 5.4
 1.3
 4.1
 0.6
 0.8
 0.4
 -0.6
-1.4
 2.0
1.8
 1.0
 2.1
-1.4
 0.7
0.1
18 GNS glucosamine (N-acetyl)-6-sulfatase 2799 0 5.4 5.5
 2.3
 3.9
 4.3
 2.2
 2.5
 1.7
 4.4
0.3
 -0.2

19 SCPEP1 serine carboxypeptidase 1 59342 0 5.3 6.0
 1.6
 3.4
 3.9
 3.2
 3.3
 5.1
 2.2
 0.4
0.3
 1.0
 1.8
20 NAGLU N-acetyl-alpha-glucosaminidase 4669 0 5.3 5.3
 1.8
 4.0
 1.7
 2.7
 4.1
 5.0
 0.0
 0.3
 -0.9
 -0.5
21 NPC2 NPC intracellular cholesterol transporter 2 10577 0 5.2 5.4
 1.6
 3.7
 3.8
 2.0
 6.8
 3.2
 2.6
1.4
 1.9

22 GM2A GM2 ganglioside activator 2760 0 5.1 5.5
 2.5
 3.5
 1.8
 3.2
 4.0
 2.1
 3.2


23 CTSB cathepsin B 1508 0 5.1 5.8
 1.3
 3.1
 5.1
 2.9
 2.0
 3.6
 1.9
0.4
 1.4
 0.4
0.4
 3.8
2.8
24 LAMP2 lysosomal associated membrane protein 2 3920 0 5.0 5.2
 1.9
 3.5
 2.4
0.6
 2.7
2.6
 3.9
2.5
 3.7
1.6
 2.8
1.9
 1.0
 0.5
-0.1
 2.1
1.0
25 ASAH1 N-acylsphingosine amidohydrolase 1 427 0 5.0 5.7
 2.1
 3.0
 4.9
 2.4
 3.0
 2.2
 1.4
0.7
0.3
 7.4
26 NUCB1 nucleobindin 1 4924 0 4.9 5.8
 1.7
 2.9
 2.6
-0.1
 1.2
0.9
 1.7
1.2
 2.0
1.0
 1.3
1.0
 1.7
 1.5
 0.8
27 SIL1 SIL1 nucleotide exchange factor 64374 0 4.9 5.1
 0.8
 3.6
 2.7
 2.4
 2.4
 1.7
 0.7
 -0.8

28 TOR3A torsin family 3 member A 64222 0 4.9 4.7
 3.2
 4.0
 1.8
 2.2
 2.3
 0.3
 0.8


29 PLBD2 phospholipase B domain containing 2 196463 0 4.9 4.7
 0.9
 3.8
 2.0
 1.1
 3.7
 4.0
 1.6
2.2
0.1
 3.0
2.4
30 IFI30 IFI30 lysosomal thiol reductase 10437 0 4.8 5.4
 2.1
 3.1
 3.1
 3.2
 4.2
 6.1
 0.9
-0.2
 0.5
-0.1
 2.6
1.9
 1.8
1.2
31 SLC66A3 solute carrier family 66 member 3 130814 0 4.8 4.3
 1.7
 4.1
 1.8
 1.3
 1.5
 -0.4
 2.7
 0.0

32 NEU1 neuraminidase 1 4758 0 4.7 5.2
 2.2
 3.1
 2.0
 1.2
 1.4
 -1.1
 2.2


33 OS9 OS9 endoplasmic reticulum lectin 10956 0 4.7 5.4
 1.1
 2.9
 3.5
 1.9
 2.3
 1.2
 2.2


34 GNPTG N-acetylglucosamine-1-phosphate transferase subunit gamma 84572 0 4.7 4.2
 1.6
 4.1
 2.7
 1.4
 0.8
 2.9
 1.1


35 PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial 5106 0 4.7 4.7
 1.7
 3.5
 3.7
-0.1
 2.0
-0.4
 0.6
-1.5
 0.8
-0.2
 0.4
-1.3
 1.2
 0.7
-0.3
 1.3
-0.7
36 DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit 1650 0 4.7 5.4
 3.0
 2.7
 1.0
 -0.4
 2.5
 2.0
 0.7
 1.9
 0.1
 0.4
37 CTSA cathepsin A 5476 0 4.6 5.2
 1.7
 2.9
 3.5
 4.8
 4.6
 2.9
 2.1
2.0
2.0
1.5
 3.6
2.3
38 PPT1 palmitoyl-protein thioesterase 1 5538 0 4.5 5.4
 1.6
 2.6
 2.4
 1.9
 4.5
 2.1
 1.1
 -0.3
 -0.4
 2.5
39 ATRAID all-trans retinoic acid induced differentiation factor 51374 0 4.5 4.7
 1.1
 3.2
 0.6
 2.3
 2.9
 3.4
 0.9


40 GBA glucosylceramidase beta 2629 0 4.4 4.2
3.6
 1.9
 3.3
 4.5
 4.9
 2.7
 2.8
-0.3
 1.9
1.0
 3.4
1.8
41 SLC3A2 solute carrier family 3 member 2 6520 0 4.4 4.9
 2.0
 2.9
 2.2
 0.7
 0.3
 -0.8
 0.8
-0.9
 -0.3
 -0.6
 0.2
42 PIGT phosphatidylinositol glycan anchor biosynthesis class T 51604 0 4.4 5.2
 1.6
 2.5
 0.5
 0.7
 1.1
 1.4
 -1.6
 -0.1
 -0.1
 0.5
43 LAMP1 lysosomal associated membrane protein 1 3916 0 4.4 4.7
 2.7
 3.0
 2.4
0.6
 2.7
2.6
 3.9
2.5
 3.7
1.6
 2.8
1.9
 1.0
 0.5
-0.1
 2.1
1.0
44 LMAN2 lectin, mannose binding 2 10960 0 4.4 4.9
 1.7
 2.8
 0.4
-0.5
 0.8
-0.1
 2.8
0.5
 0.9
0.5
 1.1
0.2
 -0.2
 1.3
 0.5
45 YIPF2 Yip1 domain family member 2 78992 0 4.4 4.4
 2.3
 3.2
 1.0
0.1
 3.0
-0.1
 3.6
1.3
 1.7
0.3
 1.5
-0.2
 0.5
 1.0
 -0.5
46 P2RX4 purinergic receptor P2X 4 5025 0 4.4 4.8
 2.5
 2.8
 3.2
 4.1
 1.3
 2.8
 0.7


47 DPP7 dipeptidyl peptidase 7 29952 0 4.4 3.8
 0.5
 3.9
 1.5
 6.0
 5.9
 3.0
 1.2


48 TPP1 tripeptidyl peptidase 1 1200 0 4.3 4.5
 1.3
 3.1
 1.8
 4.5
 5.3
 1.9
 3.1


49 MCOLN1 mucolipin TRP cation channel 1 57192 0 4.3 3.9
 2.2
 3.6
 2.4
1.0
 2.2
0.5
 1.2
0.3
 1.7
1.4
 2.5
2.1
-1.1
 -0.7
50 SUMF2 sulfatase modifying factor 2 25870 0 4.3 3.5
 2.0
 4.0
 1.3
 1.8
 3.7
 -0.0
 -1.2


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