Orthologous genes in OrthoFinder**

Species Gene Description
 gga-u.3   TLL2   tolloid-like 2 
 gga-r.3   TLL2   tolloid-like 2 
 gga-u.3   TLL1   tolloid like 1 
 hsa-u.4   TLL2   tolloid like 2 
 hsa-u.4   BMP1   bone morphogenetic protein 1 
 mmu-u.4   Tll1   tolloid-like 
 mmu-u.4   Bmp1   bone morphogenetic protein 1 
 rno-u.3   Tll1   tolloid-like 1 
 rno-u.3   Bmp1   bone morphogenetic protein 1 
 mcc-u.3   TLL1   tolloid like 1 
 mcc-u.3   BMP1   bone morphogenetic protein 1 
 cfa-u.3   BMP1   bone morphogenetic protein 1 
 cfa-u.3   TLL1   tolloid like 1 
 dre-u.3   bmp1a   bone morphogenetic protein 1a 
 dre-u.3   bmp1b   bone morphogenetic protein 1b 
 dre-u.3   tll1   tolloid-like 1 
 dme-u.3   tld   tolloid 
 dme-u.3   tok   tolkin 
 cel-u.3   nas-39   Zinc metalloproteinase nas-39 

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Top 50 coexpressed genes to TLL2 (gga-u.3 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 gga30   Pentose phosphate pathway  1 25 -
 gga10   Glycolysis / Gluconeogenesis  1 52 -
 gga4068   FoxO signaling pathway  2 122 -
 gga4060   Cytokine-cytokine receptor interaction  2 202 -
 gga4010   MAPK signaling pathway  2 260 -

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gga:TLL2 (tolloid-like 2) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

gga-u.3
for
TLL2
gga-r.3
for
TLL2
gga-u.3
for
TLL1
hsa-u.4
for
TLL2
hsa-u.4
for
BMP1
mmu-u.4
for
Tll1
mmu-u.4
for
Bmp1
rno-u.3
for
Tll1
rno-u.3
for
Bmp1
mcc-u.3
for
TLL1
mcc-u.3
for
BMP1
cfa-u.3
for
BMP1
cfa-u.3
for
TLL1
dre-u.3
for
bmp1a
dre-u.3
for
bmp1b
dre-u.3
for
tll1
dme-u.3
for
tld
dme-u.3
for
tok
cel-u.3
for
nas-39
1 ZP4 zona pellucida glycoprotein 4 395692 6.6 3.6
 0.4
-1.2

0.2
 -1.2

0.1
 -0.4

1.1
0.1
 1.7
1.3
 1.6
0.4


2 ZDHHC23 zinc finger DHHC-type containing 23 418353 4.0 2.2
 -0.1
 -0.2
 -2.5
 -1.1
 -1.4
 -0.8
 -1.3
 -0.5
 -2.0
 -0.3
 -0.4
 0.3
-0.3
 -0.3
-0.5
 1.6
-0.6
 0.1
 -2.0
3 BEND7 BEN domain containing 7 419037 4.0 2.2
 -0.8
 -0.2
 -0.2
 -0.3
 0.8
 0.2
 0.1
 0.1
 0.4
 -0.2
 0.2





4 FBP1 fructose-bisphosphatase 1 395218 3.8 2.0
 0.8
0.4
 0.5
-0.7
 -1.0
-1.4
 -0.7
-0.8
 0.3
-0.1
 0.4
-0.6
 0.6
-0.5
 0.1
-0.4
 1.4
1.2
 0.8
-0.4
 -0.3
-0.9
 -0.1
-0.3
 0.9
-0.6
 1.7
0.3
 0.9
 2.7
 -0.0
5 KIAA2022 KIAA2022 422325 3.6 2.0
 0.3
 0.0
 -2.0
 1.4
 -0.4
 1.6
 -0.9
 1.0
 -1.5

-0.5
 0.7
 -0.8


6 CADPS2 calcium dependent secretion activator 2 417756 3.5 1.9
 1.1
0.1
 1.0
-0.2
 -1.3
-1.8
 1.6
1.1
 1.1
0.4
 1.0
-0.4
 0.9
-0.5
 1.8
1.7
 -0.3
-1.5
 -0.1
-1.2
 1.5
-1.1
 1.2
0.8
 1.6
0.1
 0.7
0.1
 -0.4
 0.1
7 LOC121110044 uncharacterized LOC121110044 121110044 3.4 1.9
















8 TSPAN15 tetraspanin 15 423699 3.3 1.8
 0.1
 -0.3
 1.0
 0.4
 0.3
 -1.0
 0.2
 0.7
 1.9
 0.3
 1.4
 0.5
 -0.2
 0.1


9 TBC1D8 TBC1 domain family member 8 428012 3.2 1.8
 1.8
0.8
 0.4
0.0
 2.9
1.2
 1.4
1.1
 1.2
1.0
 0.4
0.3
 2.2
0.4
 1.7
1.4
 0.8
0.3
 1.4
0.2
 0.6
0.2
 1.4
0.7
 0.5
0.4
 1.1
1.1
 0.9
 0.7
 0.1
10 SLC4A4 solute carrier family 4 member 4 422649 3.2 1.8
 1.2
0.5
 1.4
1.1
 3.9
1.6
 1.7
1.5
 2.5
2.4
 1.5
1.0
 2.9
2.0
 1.4
1.1
 2.7
1.5
 2.1
1.5
 1.6
0.7
 2.5
1.1
 2.3
2.0
 2.5
1.1
 0.5
0.1
 1.5
-0.5
 1.9
-0.1
11 UNC79 unc-79 homolog (C. elegans) 423426 3.2 1.8
 1.5

0.7
 0.2
 -1.0
 -2.0
 1.8
 1.2
 0.5
 0.5
 1.8
1.5
 2.0
1.6
 -1.5
-2.0
 0.4
 1.2
 -0.7
12 PTPRU protein tyrosine phosphatase, receptor type U 395153 3.2 1.8
 1.9
1.5
 1.3
1.3
 1.8
1.7
 1.6
1.5
 1.4
0.6
 1.1
1.0
 2.5
0.8
 1.7
0.9
 1.6
0.0
 3.0
0.5
 2.9
0.7
 3.5
2.7
 2.1
1.4
 2.6
0.7


13 RGL1 ral guanine nucleotide dissociation stimulator like 1 424446 3.2 1.7
 1.2
0.0
 -0.6
-1.0
 2.6
-0.5
 0.1
-1.0
 1.2
0.7
 -0.2
-0.5
 1.9
0.3
 0.5
0.1
 1.1
-0.4
 0.6
-0.3
 0.7
-0.4
 0.5
0.0
 0.5
0.4
 2.0
1.0
 1.7
 1.1
 1.3
14 ABCC3 ATP binding cassette subfamily C member 3 422099 3.1 1.7
 2.2
1.2
 0.9
0.2
 3.0
2.1
 1.0
0.6
 1.1
1.0
 0.4
0.1
 2.2
0.4
 0.1
-0.1
 1.5
1.5
 1.1
1.0
 0.4
0.4
 2.0
1.9
 1.5
1.3
 2.5
2.4
 1.8
1.4
 1.1
0.7
 1.8
1.7
15 COL13A1 collagen type XIII alpha 1 chain 769037 3.1 1.7
 0.6
 0.1
 0.4
 0.7
 1.3
 0.6
 2.5
 1.9
 0.9
 0.5
 1.7
 1.7
 -1.2
 1.2


16 FLT3 fms related tyrosine kinase 3 100858422 3.1 1.7
 1.8
 0.6
 -0.6
 0.5
 0.7
 1.0
 0.2
 -0.2
 -0.4
 0.8
 1.0
 -2.5
 0.4
 0.1


17 TNFSF10 tumor necrosis factor superfamily member 10 378894 3.1 1.7
 1.4
 0.3
 0.3
 0.7
 -1.2
 1.3
 -0.2
 0.5
 -0.1
 -1.1
 -1.0
 0.6
 0.3
 -0.1


18 PPP1R16B protein phosphatase 1 regulatory subunit 16B 419170 3.0 1.7
 -0.4
 0.1
-0.4
 1.5
-1.4
 -0.3
-1.6
 1.0
-0.7
 1.2
-1.5
 0.7
-0.9
 0.5
-0.6
 0.8
-0.6
 0.5
-0.1
 0.2
-1.2
 0.3
-0.7
 0.6
-0.4
 1.8
0.7
 1.3
 0.3
 -0.9
19 RAB3IL1 RAB3A interacting protein like 1 423123 3.0 1.6
 -0.4
-0.4
 1.0
 -2.1
 1.0
-0.5
 0.2
-0.8
 0.4
-1.0
 0.6
-1.0
 1.2
-0.3
 -0.5
-1.6
 -0.1
-1.4
 0.4
-0.3
 1.4
-0.4
 0.9
-0.7
 -0.9
-1.3

-0.7
20 RP11-400G3.5 Uncharacterized protein 100858007 3.0 1.6
 0.8
0.6
 0.4
0.2
 1.5
0.5
 0.3
0.3
 1.2
0.7
 1.4
0.3
 1.5
1.1
 1.1
0.7
 0.7
0.4
 0.2
0.1
 1.0
0.8
 0.4
0.2
 1.1
0.8
 1.2
1.1

0.5
21 HS3ST3B1L heparan sulfate glucosamine 3-O-sulfotransferase 3B1-like 769421 2.9 1.6
 1.4
0.5
 2.0
0.3
 0.4
-1.0
 -1.2
 -1.0
 -0.0
-0.3
 0.2
-0.2
 0.4
0.3
 0.6
-0.2
 1.0
-1.0
 1.3
0.8
 1.4
-0.1
 0.6
-0.4
 1.7
1.0
 -1.2
 -0.2
 -0.0
22 UGT8 UDP glycosyltransferase 8 374033 2.9 1.6
 0.5
 1.3
 -1.3
 1.3
 -0.4
 1.4
 0.1
 0.5
 -0.6
 -0.4
 -0.6
 0.7
 -0.4
 -1.0
 -0.7
 -0.0
 -0.4
23 FSTL4 follistatin like 4 395163 2.9 1.6
 1.1
 0.3
 -1.7
 -1.1
 -0.6
 -1.2
 0.2
 0.5
 0.9
 -0.4
 -1.1
 0.9
 -0.5
 0.3


24 LYST lysosomal trafficking regulator 421514 2.9 1.6
 0.9

0.3
 0.1
 0.6
 0.4
 -0.4
 -0.2
 -1.6
 0.3
 -0.6
 -1.9
 0.8
 1.5
 0.4
25 USP43 ubiquitin specific peptidase 43 101751148 2.9 1.6
















26 NFIB nuclear factor I B 396209 2.9 1.6
 2.9
1.7
 -0.7
-0.8
 1.6
0.7
 1.1
0.3
 3.0
1.8
 1.4
0.4
 2.9
1.9
 3.6
1.4
 1.7
0.8
 0.4
-0.1
 0.2
 0.1
-0.2
 0.9
-1.2
 1.9
1.6
 -0.6
 0.3
 0.4
27 MANBA mannosidase beta 422712 2.8 1.6
 -0.1
 1.3
 1.3
 -0.3
 0.7
 -1.1
 0.5
 0.2
 2.2
 0.9
 -0.4
 -0.3
 -0.2
 0.7
 1.1
 0.9
 0.4
28 CLMN calmin 100858625 2.8 1.6
 0.5
 -0.2
 -0.7
 -0.8
 -0.6
 -0.5
 0.5
 -0.6
 -0.3
 1.0
 0.5
 1.1
 1.0
 1.5


29 RAB3IP RAB3A interacting protein 417850 2.8 1.6
 -0.4
-0.4
 1.0
 -2.1
 1.0
-0.5
 0.2
-0.8
 0.4
-1.0
 0.6
-1.0
 1.2
-0.3
 -0.5
-1.6
 -0.1
-1.4
 0.4
-0.3
 1.4
-0.4
 0.9
-0.7
 -0.9
-1.3

-0.7
30 PNPLA7 patatin like phospholipase domain containing 7 427774 2.8 1.6
 0.9
-1.2
 0.6
0.6
 1.6
0.9
 0.6
-0.2
 0.6
-0.2
 -0.2
-1.1
 0.6
-0.3
 -0.4
-1.1
 1.5
0.4
 0.5
-0.4
 -0.0
-0.1
 2.4
1.1
 -0.1
-0.7
 1.0
-1.5
 0.7
 1.5
 0.3
-0.5
31 ATP11C ATPase phospholipid transporting 11C 422254 2.8 1.5
 -0.2
 -0.2
 0.8
 0.7
 0.2
 1.9
 1.1
 -0.1
 -1.4
 -1.7
 0.9
 2.4
 -0.1
 -0.2


32 KPTN kaptin, actin binding protein 101752009 2.8 1.5
 0.4
 1.1
 1.1
 -0.6
 1.0
 -0.5
 1.2
 -0.1
 -0.3
 -0.3
 -0.9
 -0.9
 0.3
 -1.6


33 DSCAML1 DS cell adhesion molecule like 1 428249 2.8 1.5
 0.5
-0.8
 -0.3
 -1.7
 -0.9
-0.9
 0.8
0.2
 0.4
0.1
 0.6
0.2
 -0.5
-1.1
 0.6
-0.1
 1.4
 0.0
 3.2
0.8
 0.5
0.2
 -0.8
-1.5
 1.2
1.0
 1.6
1.4
34 RNF128 ring finger protein 128, E3 ubiquitin protein ligase 422382 2.8 1.5
 -0.2
 0.6
 -0.1
 0.6
 0.7
 1.0
 -0.2
 2.0
 -0.2
 -0.2
 -0.2
 1.6
 -0.0
 -0.3


35 PCNX2 pecanex homolog 2 (Drosophila) 428587 2.8 1.5
 -0.4
-0.7
 0.9
 -0.5
 1.2
1.2
 1.3
0.2
 0.3
-0.0
 1.3
-0.3
 0.5
0.3
 -0.8
-1.0
 1.5
-1.3
 0.3
-0.3
 0.9
0.3
 -0.5
-0.6
 -0.2
-0.7
 -0.8
 0.3
 1.2
36 SLC39A8 solute carrier family 39 member 8 430411 2.8 1.5
 0.3
0.2
 0.2
-0.5
 3.9
1.0
 0.6
-0.3
 3.2
0.1
 2.1
0.8
 1.9
0.6
 0.8
0.3
 1.2
0.8
 2.8
1.1
 1.9
0.5
 0.4
0.2
 -0.6
-1.2
 0.3
-0.2

-0.1
37 FAM169A family with sequence similarity 169 member A 431595 2.8 1.5
 1.5
 0.8
 -1.7
 -0.6
 -1.7
 1.7
 -1.9
 0.3
 -2.3
 -1.6
 -0.1
 -0.9
 -0.7
 1.4


38 SLC45A3 solute carrier family 45 member 3 771751 2.8 1.5
 -0.2
 0.8
 0.1
 0.4
 1.6
 -0.8
 0.6
 0.4
 1.3
 2.3
 0.3
 2.8
 -0.3
 -0.4


39 FAAHL fatty acid amide hydrolase-like 418339 2.8 1.5
















40 USH1C USH1 protein network component harmonin 423073 2.8 1.5
 1.1
 0.6
 -0.0
 -1.1
 -0.7
 0.5
 -0.7
 -1.0
 1.2
 0.9
 0.5
 -1.8
 0.8
 0.5
 -0.1
 -0.1
41 PLEKHH1 pleckstrin homology, MyTH4 and FERM domain containing H1 423270 2.8 1.5
 2.0
0.9
 1.7
-1.1
 0.1
-0.4
 0.4
-0.9
 0.7
-0.6
 0.1
-1.8
 1.2
0.8
 0.7
-0.9
 1.3
-0.6
 0.8
 2.0
-0.9
 1.2
0.7
 0.7
-0.3
 1.2
1.0
 0.6
 -0.2
 0.2
42 TMEM220 transmembrane protein 220 417311 2.7 1.5
 0.6

-1.2
 0.2
 -0.8
 0.5

0.4
 -0.3
 0.3
 0.1
 0.3


43 RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 421240 2.7 1.5
 0.4
0.3
 0.2
-0.3
 -0.3
-0.9
 0.5
-0.5
 -1.0
-1.1
 0.2
-0.2
 -0.8
-0.9
 0.2
-0.1
 -0.3
-1.3
 0.6
0.5
 1.2
1.0
 1.6
-0.4
 -0.2
-0.4
 1.0
0.8
 -0.7
 -0.1
 1.7
44 FAM178B family with sequence similarity 178, member B 425134 2.7 1.5
 -1.6















45 INSIG2 insulin induced gene 2 424276 2.7 1.5
 0.5
0.4
 -0.9
-1.0
 -0.1
-0.4
 -0.2
-0.8
 1.3
-0.8
 -0.3
-0.3
 1.3
-0.3
 1.1
-0.2
 0.4
-0.1
 0.1
 -0.0
 1.3
-1.0
 0.1
-1.1
 0.7
-1.1


46 LGR5 leucine rich repeat containing G protein-coupled receptor 5 427867 2.7 1.5
 1.4
 0.9
 -0.4
 1.2
 0.8
 0.3
 0.9
 0.9
 -0.9
 0.1
 0.3





47 PEX26 peroxisomal biogenesis factor 26 418165 2.7 1.5
 -0.4
 -0.1
 1.1
 0.1
 0.0
 -1.2
 -1.9
 -0.1
 -0.1
 -0.8
 -0.8
 -0.5
 1.8
 0.5


48 TGFBR2 transforming growth factor beta receptor 2 396399 2.7 1.5
 2.5
 -0.7
 -0.2
 0.2
 -0.2
 -0.4
 2.5
 -0.7
 -0.3
 0.5
 0.2
 0.2
 -0.4
 -1.0


49 GRID2 glutamate ionotropic receptor delta type subunit 2 422520 2.7 1.5
 1.3

2.5
 0.2
 1.5
 1.4
 1.4
 1.1

1.7
 0.4
 0.3


50 ITGB4 integrin subunit beta 4 417374
0.2
 0.5
 2.4
 0.5
 1.4
 1.0
 0.5
 0.1
 1.4
 1.1
 2.2
 0.2
 1.0
 0.8


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