Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-r.6   DR1   down-regulator of transcription 1 
 hsa-u.4   DR1   down-regulator of transcription 1 
 hsa-m.7   DR1   down-regulator of transcription 1 
 hsa-m2.4   DR1   down-regulator of transcription 1 
 mcc-u.3   DR1   down-regulator of transcription 1 
 mmu-u.4   Dr1   down-regulator of transcription 1 
 rno-u.3   Dr1   down-regulator of transcription 1 
 cfa-u.3   DR1   down-regulator of transcription 1 
 gga-u.3   DR1   down-regulator of transcription 1 
 dre-u.3   dr1   down-regulator of transcription 1 
 dme-u.3   NC2beta   Negative Cofactor 2beta 
 cel-u.3   dro-1   Down-regulator of transcription 1 
 sce-u.3   NCB2   negative cofactor 2 transcription regulator complex subunit NCB2 

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Top 50 coexpressed genes to DR1 (hsa-r.6 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa4014   Ras signaling pathway  4 200 2.52
 hsa4611   Platelet activation  3 111 2.35
 hsa4062   Chemokine signaling pathway  3 192 -
 hsa4015   Rap1 signaling pathway  3 210 -
 hsa4024   cAMP signaling pathway  3 221 -

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hsa:DR1 (down-regulator of transcription 1) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-r.6
for
DR1
hsa-u.4
for
DR1
hsa-m.7
for
DR1
hsa-m2.4
for
DR1
mcc-u.3
for
DR1
mmu-u.4
for
Dr1
rno-u.3
for
Dr1
cfa-u.3
for
DR1
gga-u.3
for
DR1
dre-u.3
for
dr1
dme-u.3
for
NC2beta
cel-u.3
for
dro-1
sce-u.3
for
NCB2
1 LIN7C lin-7 homolog C, crumbs cell polarity complex component 55327 0 8.6 6.2
 1.0
 2.2
 1.7
0.3
 5.4
0.4
 2.5
-0.7
 -1.0
-1.0
 0.4
-1.4
 0.6
-0.2
 2.8
 3.5
2 RNF11 ring finger protein 11 26994 0 7.9 6.9
 2.9
 4.3
 3.5
 2.9
 1.9
 2.6
 2.8
 2.2
-0.0
 0.5
 0.3
3 C1orf52 chromosome 1 open reading frame 52 148423 0 7.7 6.7
 2.2
 4.2
 2.6
 4.2
 2.3
 2.3
 2.9
 -1.0


4 BAG4 BAG cochaperone 4 9530 0 7.6 6.3
 2.8
 3.6
 2.7
 3.5
 3.3
 1.1
 0.5
 3.4
 0.4

5 ARF6 ADP ribosylation factor 6 382 0 7.5 5.7
 2.3
 2.5
 2.3
 4.2
 4.6
 1.3
 0.5
 1.7
-0.3
 -0.2
 2.6
6 PCNP PEST proteolytic signal containing nuclear protein 57092 0 7.5 5.1
 1.1
 1.4
 3.6
 1.5
 3.3
 1.5
 3.1
 0.6


7 SIKE1 suppressor of IKBKE 1 80143 0 7.4 6.0
 1.8
 3.2
 5.9
1.1
 4.1
2.4
 4.8
1.9
 2.8
0.2
 4.2
1.5
 2.3
-0.4
 0.5

8 MTF2 metal response element binding transcription factor 2 22823 1 7.0 7.5
 3.5
 6.2
 5.8
-0.1
 1.1
-0.3
 1.0
-0.8
 2.5
-0.5
 2.7
-2.2
 2.6
1.2
 0.0

9 ZNF644 zinc finger protein 644 84146 0 7.0 6.9
 2.4
 5.1
 2.8
 3.2
 3.3
2.6
 0.8


10 GPBP1L1 GC-rich promoter binding protein 1 like 1 60313 0 7.0 6.4
 2.3
 4.3
 2.0
 2.5
 1.6
 1.4
 0.0
 0.4


11 UHMK1 U2AF homology motif kinase 1 127933 0 6.9 5.7
 0.6
 3.2
 1.8
 2.2
 2.3
 1.6
 1.1
 0.8


12 BCL10 BCL10 immune signaling adaptor 8915 1 6.8 6.6
 3.0
 4.7
 0.7
 3.9
 3.5
 3.5
 1.5
 -0.5


13 BTF3L4 basic transcription factor 3 like 4 91408 0 6.8 5.6
 2.3
 3.0
 3.3
0.7
 2.2
0.8
 3.2
1.4
 2.4
-0.4
 1.6
1.6
 1.9
-1.4
 -0.2
-1.7
 0.6
 1.3
-1.7
14 RAB21 RAB21, member RAS oncogene family 23011 0 6.7 4.9
 0.7
 1.8
 4.2
 3.6
 4.1
 1.3
 3.6
 0.9
 3.0
 2.1
15 TMEM167B transmembrane protein 167B 56900 0 6.7 6.1
 1.8
 4.0
 2.4
 1.8
 2.6
1.1
 4.1
 -0.2
 -0.3


16 GNAI3 G protein subunit alpha i3 2773 0 6.7 6.0
 3.0
 3.8
 3.0
0.8
 4.4
1.0
 3.3
2.1
 3.1
2.1
 2.9
1.4
 2.7
2.1
 -0.2
-0.4
 3.5
1.8
 1.6
-0.4
17 CSNK1A1 casein kinase 1 alpha 1 1452 0 6.7 5.5
 1.5
 3.0
 0.4
-1.3
 3.0
0.8
 3.5
3.0
 2.6
0.3
 2.4
0.7
 3.3
-0.1
 1.2
-0.2
 -1.1
-1.3
 -0.9
18 BNIP2 BCL2 interacting protein 2 663 0 6.7 5.0
 1.4
 2.1
 3.0
0.5
 1.5
0.0
 0.9
-0.2
 1.3
-0.7
 0.6
0.4
 0.8
0.4
 -0.3

19 GTF2A1 general transcription factor IIA subunit 1 2957 0 6.7 6.1
 1.0
 4.0
 0.4
 4.6
 0.9
 1.8
 3.8
 3.6
 3.3
 1.6
 0.4
20 SMNDC1 survival motor neuron domain containing 1 10285 0 6.6 5.9
 2.7
 3.7
 5.1
 5.3
 3.8
 1.0
 3.3
 1.9
 2.1
 1.1
21 MOB1A MOB kinase activator 1A 55233 0 6.6 5.2
 1.7
 2.5
 4.9
3.1
 5.9
4.8
 4.0
4.0
 1.9
1.5
 1.1
0.9
 2.2
1.9
 -0.2
-0.4
 1.7
0.8
 -0.7
-0.9
22 TMED5 transmembrane p24 trafficking protein 5 50999 1 6.6 6.4
 2.4
 4.7
 1.2
-0.2
 2.7
-1.2
 2.7
-1.1
 2.7
-0.6
 3.7
 1.5
1.3
 0.5
0.4
 2.1
23 RAP1A RAP1A, member of RAS oncogene family 5906 0 6.5 5.0
 0.8
 2.3
 3.8
2.9
 6.7
3.3
 3.2
3.1
 3.7
2.0
 4.7
3.5
 3.0
2.5
 0.1
0.1
 1.1
1.0
 1.2
1.0
24 MZT1 mitotic spindle organizing protein 1 440145 0 6.5 6.4
 0.8
4.7
3.7
 -1.0
 3.5
 1.4


25 C1D C1D nuclear receptor corepressor 10438 0 6.4 3.7
 1.7
 0.1
 4.3
 3.7
 2.0
 1.6
 3.1
 1.7
3.1
 1.4
26 CGGBP1 CGG triplet repeat binding protein 1 8545 0 6.4 4.3
 1.0
 1.2
 3.4
 7.2
 6.8
 0.8
 2.1



27 ANKRD13C ankyrin repeat domain 13C 81573 0 6.4 6.1
 2.8
 4.3
 3.0
 3.4
 3.7
2.5
 3.0
 3.6
 1.6
 0.3
 1.8
28 RAB14 RAB14, member RAS oncogene family 51552 0 6.4 4.4
 0.6
 1.3
 3.2
 1.9
 3.2
 1.1
 2.5
 0.5
-1.0
 0.2
 0.7
29 NRAS NRAS proto-oncogene, GTPase 4893 0 6.3 5.5
 3.1
 3.3
 3.8
2.9
 6.7
3.3
 3.2
3.1
 3.7
2.0
 4.7
3.5
 3.0
2.5
 0.1
0.1
 1.1
1.0
 1.2
1.0
30 C2orf69 chromosome 2 open reading frame 69 205327 0 6.2 5.4
 1.1
 3.3
 3.0
1.4
 0.0
 4.2
 -0.6
 -0.6

31 FBXO28 F-box protein 28 23219 0 6.2 5.4
 1.4
 3.2
 3.5
 2.7
 3.2
 1.1
 -1.1
 -0.3
 1.4

32 PRELID3B PRELI domain containing 3B 51012 0 6.2 4.6
 1.1
 1.9
 3.3
-0.1
 0.9
-0.9
 2.3
-0.2
 -0.1
-0.4
 2.5
1.9
 2.3
-0.4
-0.4
 0.4
-0.1
33 PPP1CB protein phosphatase 1 catalytic subunit beta 5500 0 6.2 4.9
 0.8
 2.4
 5.1
2.2
 5.4
0.4
 4.5
4.2
 3.4
3.0
 4.0
1.3
 1.2
1.2
 0.3
0.2
 2.1
0.8
 0.5
0.3
34 ARPP19 cAMP regulated phosphoprotein 19 10776 0 6.2 5.2
 1.7
 2.9
 2.5
0.0
 0.4
-1.6
 2.1
0.2
 1.8
0.6
 0.2
-1.3
 3.6
2.3
 1.7
 0.4
 2.7
0.8
35 OSBPL8 oxysterol binding protein like 8 114882 0 6.2 4.9
 0.5
 2.4
 3.4
-1.7
 1.8
-1.5
 2.9
-1.1
 1.3
-0.2
 0.3
-0.3
 -0.3
-0.4
 -0.2
 -1.4
 -0.4
-0.4
36 CBFB core-binding factor subunit beta 865 0 6.1 5.4
 1.5
 3.3
 4.0
 3.6
 6.3
 1.1
 1.6
 0.1
 4.7
-0.1

37 SLAIN2 SLAIN motif family member 2 57606 0 6.1 4.2
 2.0
 1.2
 1.9
 4.3
 5.0
 0.6
 1.7
 1.5


38 SERBP1 SERPINE1 mRNA binding protein 1 26135 1 6.1 4.8
 2.8
 2.3
 3.2
 1.3
 -0.2
 1.4
 2.7
 0.4
-0.0
 1.3
0.7
 0.6
39 SELENOF selenoprotein F 9403 1 6.1 5.5
 2.2
 3.6
 4.0
 1.5
 1.3
 1.9
0.7
 1.1
 -0.2
 3.9
 -0.7
40 FEM1B fem-1 homolog B 10116 0 6.1 5.3
 2.5
 3.3
 1.0
 3.1
 1.8
 0.9
 1.2
 0.4
 1.2

41 THAP1 THAP domain containing 1 55145 0 6.1 5.1
 1.2
 2.9
 5.9
0.8
 5.2
-1.7
 2.0
-1.2
 0.2
-0.5
 0.6
 1.8
1.4
 0.4
0.1

42 SHOC2 SHOC2 leucine rich repeat scaffold protein 8036 0 6.0 5.4
 1.1
 3.5
 4.4
 4.0
 1.4
 4.0
 1.3
 3.7
 1.0
 -1.2
43 AKIRIN1 akirin 1 79647 0 6.0 5.5
 3.1
 3.6
 3.7
3.2
 6.0
3.8
 6.2
5.5
 2.0
0.9
 3.5
 1.3
0.8
 1.0
-0.6
 0.2
44 RCHY1 ring finger and CHY zinc finger domain containing 1 25898 0 5.9 5.2
 1.9
 3.3
 2.3
 1.9
 2.0
 2.6
 0.2
 -0.4
 -0.7

45 TBL1XR1 TBL1X receptor 1 79718 0 5.9 4.5
 -0.0
 2.0
 1.8
0.0
 1.4
-0.2
 1.7
 1.1
0.7
 1.1
-0.1
 3.1
1.3
 -1.9
-0.9
46 TCEA1 transcription elongation factor A1 6917 0 5.8 4.7
 0.4
 2.4
 6.5
-0.7
 6.0
-1.1
 4.7
2.2
 1.6
-1.0
 1.4
-0.6
 3.6
0.7
 2.9
 0.8
 -1.1
47 BTBD1 BTB domain containing 1 53339 0 5.8 4.6
 1.5
 2.2
 0.5
-0.0
 0.3
-1.5
 1.6
-0.1
 0.6
0.2
 3.1
-0.0
 1.2
0.9
-2.3
48 SLC35A3 solute carrier family 35 member A3 23443 0 5.8 4.7
 1.1
 2.4
 1.4
-2.2
 3.7
-0.7
 2.9
-0.9
 1.9
-1.3
 2.2
0.3
 2.6
0.9
 0.1
 4.3
3.3
49 RAB33B RAB33B, member RAS oncogene family 83452 0 5.8 5.4
 0.7
 3.7
 1.2
-0.8
 2.2
-0.9
 1.8
-1.4
 0.9
 3.3
0.2
 0.5
0.5
3.6
50 RTCA RNA 3'-terminal phosphate cyclase 8634 0 5.8 5.1
 3.1
 3.1
 1.5
 1.6
 0.6
 2.2
 2.7
 3.6
 3.2

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