Orthologous genes in OrthoFinder**

Species Gene Description
 hsa-r.6   DNASE2   deoxyribonuclease 2, lysosomal 
 hsa-u.4   DNASE2   deoxyribonuclease 2, lysosomal 
 hsa-m.7   DNASE2   deoxyribonuclease 2, lysosomal 
 hsa-m2.4   DNASE2   deoxyribonuclease 2, lysosomal 
 mcc-u.3   DNASE2   deoxyribonuclease 2, lysosomal 
 mmu-u.4   Dnase2a   deoxyribonuclease II alpha 
 rno-u.3   Dnase2   deoxyribonuclease 2, lysosomal 
 cfa-u.3   DNASE2   deoxyribonuclease 2, lysosomal 
 dre-u.3   dnase2   deoxyribonuclease II, lysosomal 
 dme-u.3   DNaseII   Deoxyribonuclease II 
 cel-u.3   crn-7   Cell-death-related nuclease 7 
 cel-u.3   nuc-1   Deoxyribonuclease-2 

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Top 50 coexpressed genes to DNASE2 (hsa-r.6 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 hsa4142   Lysosome  23 124 7.09
 hsa511   Other glycan degradation  7 15 7.02
 hsa4141   Protein processing in endoplasmic reticulum  7 159 5.11
 hsa531   Glycosaminoglycan degradation  6 16 6.89
 hsa513   Various types of N-glycan biosynthesis  5 30 5.73

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hsa:DNASE2 (deoxyribonuclease 2, lysosomal) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID CoexPub LINK Target Reference

hsa-r.6
for
DNASE2
hsa-u.4
for
DNASE2
hsa-m.7
for
DNASE2
hsa-m2.4
for
DNASE2
mcc-u.3
for
DNASE2
mmu-u.4
for
Dnase2a
rno-u.3
for
Dnase2
cfa-u.3
for
DNASE2
dre-u.3
for
dnase2
dme-u.3
for
DNaseII
cel-u.3
for
crn-7
cel-u.3
for
nuc-1
1 PSAP prosaposin 5660 0 7.6 6.9
 2.9
 4.5
 1.7
 2.6
0.1
 3.8
 3.1
 1.9
 1.3
 1.8
-0.6
 5.7
2.5
2 HEXB hexosaminidase subunit beta 3074 0 7.2 7.0
 2.3
 5.1
 3.7
3.5
 3.6
2.2
 4.6
2.1
 5.2
4.2
 0.6
-0.1
 1.1
0.6
 1.4
 3.1
3 GLB1 galactosidase beta 1 2720 1 6.9 6.7
 2.9
 4.8
 3.2
2.4
 2.5
1.3
 3.1
1.4
 2.3
2.2
 2.4
1.7
 3.3
1.2
 1.6
 0.5
4 CTSD cathepsin D 1509 0 6.6 6.2
 2.6
 4.3
 4.7
0.7
 2.8
0.9
 5.8
0.6
 2.2
2.1
 2.6
0.7
 2.5
0.1
 1.1
1.0
 5.0
3.9
5 HEXA hexosaminidase subunit alpha 3073 0 6.5 6.1
 2.2
 4.2
 3.7
3.5
 3.6
2.2
 4.6
2.1
 5.2
4.2
 0.6
-0.1
 1.1
0.6
 1.4
 3.1
6 GRN granulin precursor 2896 0 6.5 5.8
 2.3
 3.7
 2.0
 4.5
 4.8
 4.7
 3.0
1.5
-0.2
 4.7
7 MAN2B1 mannosidase alpha class 2B member 1 4125 0 6.3 6.2
 1.5
 4.6
 3.3
 3.2
 2.1
 6.0
 1.8
 3.1
1.0
 -0.0
 0.5
8 MANBA mannosidase beta 4126 0 6.2 5.4
 2.1
 3.3
 2.9
 3.5
 0.9
 1.8
 1.9
 0.2
 -1.0
 2.8
9 GLMP glycosylated lysosomal membrane protein 112770 0 6.2 5.7
 1.5
 3.8
 3.6
 3.4
 4.1
 3.1
 1.6


10 PLD3 phospholipase D family member 3 23646 0 6.1 5.6
 1.5
 3.7
 2.4
 2.8
 5.2
 2.5
 2.8
 -0.2
 0.6
0.2
 4.4
0.2
11 ATP6AP1 ATPase H+ transporting accessory protein 1 537 0 6.1 5.8
 1.9
 4.1
 2.9
 1.8
 2.8
 2.3
 1.9
0.5
 2.5
-1.1
 0.4
 0.1
12 ERP29 endoplasmic reticulum protein 29 10961 0 6.1 6.3
 2.9
 4.9
2.6
 2.7
 -0.1
0.8

13 SCPEP1 serine carboxypeptidase 1 59342 0 6.0 5.3
 1.6
 3.4
 3.9
 3.2
 3.3
 5.1
 2.2
 0.4
0.3
 1.0
 1.8
14 NUCB1 nucleobindin 1 4924 0 5.8 4.9
 1.7
 2.9
 2.6
-0.1
 1.2
0.9
 1.7
1.2
 2.0
1.0
 1.3
1.0
 1.7
 1.5
 0.8
15 CTSB cathepsin B 1508 0 5.8 5.1
 1.3
 3.1
 5.1
 2.9
 2.0
 3.6
 1.9
0.4
 1.4
 0.4
0.4
 3.8
2.8
16 ASAH1 N-acylsphingosine amidohydrolase 1 427 0 5.7 5.0
 2.1
 3.0
 4.9
 2.4
 3.0
 2.2
 1.4
0.7
0.3
 7.4
17 GM2A GM2 ganglioside activator 2760 0 5.5 5.1
 2.5
 3.5
 1.8
 3.2
 4.0
 2.1
 3.2


18 GNS glucosamine (N-acetyl)-6-sulfatase 2799 0 5.5 5.4
 2.3
 3.9
 4.3
 2.2
 2.5
 1.7
 4.4
0.3
 -0.2

19 CRTAP cartilage associated protein 10491 0 5.5 5.5
 2.1
 4.3
 1.6
0.3
 2.4
0.5
 2.0
1.5
 0.8
0.5
 -0.1
-1.0
0.6
 -0.4
20 DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit 1650 0 5.4 4.7
 3.0
 2.7
 1.0
 -0.4
 2.5
 2.0
 0.7
 1.9
 0.1
 0.4
21 NPC2 NPC intracellular cholesterol transporter 2 10577 0 5.4 5.2
 1.6
 3.7
 3.8
 2.0
 6.8
 3.2
 2.6
1.4
 1.9

22 IFI30 IFI30 lysosomal thiol reductase 10437 0 5.4 4.8
 2.1
 3.1
 3.1
 3.2
 4.2
 6.1
 0.9
-0.2
 0.5
-0.1
 2.6
1.9
 1.8
1.2
23 FUCA1 alpha-L-fucosidase 1 2517 0 5.4 5.8
 1.6
 4.8
 2.5
1.2
 3.5
2.0
 4.5
1.9
 3.9
1.6
 2.5
1.5
2.1
 -0.7
24 MAN1B1 mannosidase alpha class 1B member 1 11253 0 5.4 5.4
 1.3
 4.1
 0.6
 0.8
 0.4
 -0.6
-1.4
 2.0
1.8
 1.0
 2.1
-1.4
 0.7
0.1
25 OS9 OS9 endoplasmic reticulum lectin 10956 0 5.4 4.7
 1.1
 2.9
 3.5
 1.9
 2.3
 1.2
 2.2


26 PPT1 palmitoyl-protein thioesterase 1 5538 0 5.4 4.5
 1.6
 2.6
 2.4
 1.9
 4.5
 2.1
 1.1
 -0.3
 -0.4
 2.5
27 NAGLU N-acetyl-alpha-glucosaminidase 4669 0 5.3 5.3
 1.8
 4.0
 1.7
 2.7
 4.1
 5.0
 0.0
 0.3
 -0.9
 -0.5
28 LAMP2 lysosomal associated membrane protein 2 3920 0 5.2 5.0
 1.9
 3.5
 2.4
0.6
 2.7
2.6
 3.9
2.5
 3.7
1.6
 2.8
1.9
 1.0
 0.5
-0.1
 2.1
1.0
29 CTSA cathepsin A 5476 0 5.2 4.6
 1.7
 2.9
 3.5
 4.8
 4.6
 2.9
 2.1
2.0
2.0
1.5
 3.6
2.3
30 PIGT phosphatidylinositol glycan anchor biosynthesis class T 51604 0 5.2 4.4
 1.6
 2.5
 0.5
 0.7
 1.1
 1.4
 -1.6
 -0.1
 -0.1
 0.5
31 NEU1 neuraminidase 1 4758 0 5.2 4.7
 2.2
 3.1
 2.0
 1.2
 1.4
 -1.1
 2.2


32 SIL1 SIL1 nucleotide exchange factor 64374 0 5.1 4.9
 0.8
 3.6
 2.7
 2.4
 2.4
 1.7
 0.7
 -0.8

33 BLVRB biliverdin reductase B 645 0 5.1 5.7
 1.8
 4.9
 4.1
 4.0
 2.2
 3.1
 0.6
 0.0

34 PRCP prolylcarboxypeptidase 5547 0 5.1 4.3
 1.6
 2.4
 2.1
 2.3
 4.0
 2.6
 4.0
 2.6
 2.3
 1.8
35 GET3 guided entry of tail-anchored proteins factor 3, ATPase 439 0 5.0 4.2
 1.8
 2.5
 2.0
 0.2
 1.7
 3.6
 1.1
 -0.0
 2.7
 0.5
36 LMAN2 lectin, mannose binding 2 10960 0 4.9 4.4
 1.7
 2.8
 0.4
-0.5
 0.8
-0.1
 2.8
0.5
 0.9
0.5
 1.1
0.2
 -0.2
 1.3
 0.5
37 SLC3A2 solute carrier family 3 member 2 6520 0 4.9 4.4
 2.0
 2.9
 2.2
 0.7
 0.3
 -0.8
 0.8
-0.9
 -0.3
 -0.6
 0.2
38 P2RX4 purinergic receptor P2X 4 5025 0 4.8 4.4
 2.5
 2.8
 3.2
 4.1
 1.3
 2.8
 0.7


39 ACP5 acid phosphatase 5, tartrate resistant 54 0 4.8 4.1
 2.0
 2.4
 3.5
 1.3
 2.5
 2.9
 0.9
-0.0
3.3
 0.1
40 PLBD2 phospholipase B domain containing 2 196463 0 4.7 4.9
 0.9
 3.8
 2.0
 1.1
 3.7
 4.0
 1.6
2.2
0.1
 3.0
2.4
41 LAMP1 lysosomal associated membrane protein 1 3916 0 4.7 4.4
 2.7
 3.0
 2.4
0.6
 2.7
2.6
 3.9
2.5
 3.7
1.6
 2.8
1.9
 1.0
 0.5
-0.1
 2.1
1.0
42 PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial 5106 0 4.7 4.7
 1.7
 3.5
 3.7
-0.1
 2.0
-0.4
 0.6
-1.5
 0.8
-0.2
 0.4
-1.3
 1.2
 0.7
-0.3
 1.3
-0.7
43 ATRAID all-trans retinoic acid induced differentiation factor 51374 0 4.7 4.5
 1.1
 3.2
 0.6
 2.3
 2.9
 3.4
 0.9


44 TOR3A torsin family 3 member A 64222 0 4.7 4.9
 3.2
 4.0
 1.8
 2.2
 2.3
 0.3
 0.8


45 NUPR1 nuclear protein 1, transcriptional regulator 26471 0 4.7 5.4
 2.2
 4.9
 2.0
 0.6
 2.2
 1.6
 -0.5
 0.3

46 TMEM205 transmembrane protein 205 374882 0 4.6 4.2
 1.8
 2.7







47 TMED1 transmembrane p24 trafficking protein 1 11018 0 4.6 4.0
 1.5
 2.4
 1.3
0.8
 1.0
0.7
 2.8
-0.9
 1.9
-0.7
 2.0
1.4
 2.2
0.7
 0.0
 -1.2
48 RPN2 ribophorin II 6185 0 4.6 3.9
 1.6
 2.4
 1.6
 -0.4
 0.4
 0.9
 1.0
 0.8
 0.4
 0.8
49 GUSB glucuronidase beta 2990 0 4.6 4.2
 1.2
 2.9
 3.4
 1.6
 5.0
 2.7
 1.4
 0.9
-0.2
 0.8
 0.1
50 LAPTM4A lysosomal protein transmembrane 4 alpha 9741 0 4.5 3.2
 1.2
 1.0
 0.7
-1.2
 0.9
0.4
 1.8
1.3
 1.6
-1.0
 -0.4
-0.6
 0.2

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