Orthologous genes in OrthoFinder**

Species Gene Description
 rno-m.5   Mdm2   MDM2 proto-oncogene 
 rno-u.3   Mdm2   MDM2 proto-oncogene 
 rno-r.3   Mdm2   MDM2 proto-oncogene 
 mmu-u.4   Mdm2   transformed mouse 3T3 cell double minute 2 
 hsa-u.4   MDM2   MDM2 proto-oncogene 
 mcc-u.3   MDM2   MDM2 proto-oncogene 
 cfa-u.3   MDM2   MDM2 proto-oncogene 
 gga-u.3   MDM2   MDM2 proto-oncogene 
 dre-u.3   mdm2   MDM2 proto-oncogene 

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Top 50 coexpressed genes to Mdm2 (rno-m.5 coexpression data)

 KEGG ID   Pathway name   #genes in coex list   #genes in genome   -log10(p)   Link to the KEGG* map 
(Multiple genes)
 rno5225   Hepatocellular carcinoma  4 165 2.81
 rno4115   p53 signaling pathway  5 68 2.94
 rno5203   Viral carcinogenesis  4 221 -
 rno5206   MicroRNAs in cancer  4 292 -
 rno5200   Pathways in cancer  5 538 -

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rno:Mdm2 (MDM2 proto-oncogene) External Links;


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Show Coexpressed Genes
UMAP
Gene Function KEGG Entrez
Gene
ID		 Other ID LINK Target Reference

rno-m.5
for
Mdm2
rno-u.3
for
Mdm2
rno-r.3
for
Mdm2
mmu-u.4
for
Mdm2
hsa-u.4
for
MDM2
mcc-u.3
for
MDM2
cfa-u.3
for
MDM2
gga-u.3
for
MDM2
dre-u.3
for
mdm2
1 Txnrd1 thioredoxin reductase 1 58819 3.5 5.4
 1.6
 6.4
-2.0
 3.2
-0.1
 3.1
-2.2
 1.2
-0.5
 1.1
0.2
 0.8
0.2
2 Aen apoptosis enhancing nuclease 361594 3.0 5.9
 2.7
 6.2
 9.6
 1.2
 2.4
 1.4
3 Zfp655 zinc finger protein 655 360764 3.0 4.1
 1.0
 2.0
 0.1
 3.0
 1.4

4 Gdf15 growth differentiation factor 15 29455 2.9 5.2
 2.0
 3.5
 7.0
 1.0
 -0.1
 0.8
5 Srxn1 sulfiredoxin 1 296271 2.8 4.9
 1.9
 3.4
 2.0
 1.4
 0.7
 -1.7
 -1.3
6 Plk2 polo-like kinase 2 83722 2.8 4.4
 1.5
 5.0
1.4
 4.5
3.8
 0.2
-0.2
 1.2
0.8
 0.7
-0.1
 1.4
0.5
7 Oser1 oxidative stress responsive serine-rich 1 296346 2.7 6.0
 3.0
 3.4
 0.8
 0.2
 0.7
 2.1
 2.3
8 Ccnl1 cyclin L1 114121 2.7 3.9
 1.1
 3.6
3.1
 -0.2
-0.6
 2.1
 0.4
 2.9
1.8
 1.8
1.2
9 Tp53inp1 tumor protein p53 inducible nuclear protein 1 297822 2.7 4.8
 1.9
 7.2
1.6
 8.4
0.9
 4.4
0.2
 1.2
-0.1
 0.7
0.4
 4.4
2.3
10 Mdm4 MDM4 regulator of p53 304798 2.7 3.5
 0.7
 4.3
 1.3
 4.2
 1.7
 4.1
 -1.2
11 Riok3 RIO kinase 3 361293 2.6 4.8
 2.0
 4.3
 1.8
 1.3
 0.5
 1.4
 3.4
12 Cdkn1a cyclin-dependent kinase inhibitor 1A 114851 2.6 4.5
 1.8
 6.3
2.9
 4.7
 3.0
 6.5
13 Slc35e3 solute carrier family 35, member E3 362883 2.5 5.5
 2.8
 2.5
 4.4
 6.4
 3.5
 3.3
 1.6
14 Ccng1 cyclin G1 25405 2.5 5.9
 3.1
 9.2
3.2
 5.5
1.7
 2.3
 4.8
3.1
 2.8
 8.4
-0.8
15 Prdm4 PR/SET domain 4 170820 2.5 3.0
 0.4
 4.0
 1.1
 -0.6
 1.4
 -0.4
 2.1
16 Gadd45a growth arrest and DNA-damage-inducible, alpha 25112 2.5 5.0
 2.3
 2.9
2.2
 4.6
0.9
 2.6
1.9
 1.9
0.8
 0.9
0.9
 4.9
1.5
17 Smndc1 survival motor neuron domain containing 1 287768 2.4 4.1
 1.5
 3.2
 2.1
 3.7
 1.3
 0.9
 1.5
18 Oga O-GlcNAcase 154968 2.4 2.2
 -0.2
 3.0
 0.9
 3.2
 0.9
 2.4
 0.7
-0.1
19 Ipo5 importin 5 306182 2.4 4.1
 1.6
 0.9
0.0
 0.2
-0.0
 -0.1
-0.3
 2.3
0.7
 0.0
 0.3
20 Septin2 septin 2 117515 2.3 3.5
 1.0
 1.1
0.1
 0.6
-0.0
 0.1
-0.2
 1.3
0.2
 1.6
1.4
 1.4
1.0
21 Agfg1 ArfGAP with FG repeats 1 363266 2.3 2.8
 0.4
 1.0
 1.8
 1.3
 2.6
 -0.7
 1.3
-0.8
22 Pi4k2b phosphatidylinositol 4-kinase type 2 beta 305419 2.3 2.9
 0.5
 3.4
1.0
 2.0
 1.7
-0.3
 2.0
0.4
 -1.1
-1.1
 1.0
-0.9
23 Senp2 SUMO specific peptidase 2 78973 2.3 3.5
 1.1
 3.7
1.0
 1.9
1.5
 1.8
1.4
 0.7
0.5
 2.4
0.6
 0.6
0.4
24 Clp1 cleavage factor polyribonucleotide kinase subunit 1 311166 2.3 4.6
 2.1
 1.2
 0.9
 0.6
 1.8
 -1.2
 -0.0
25 Rsrc2 arginine and serine rich coiled-coil 2 360807 2.3 4.1
 1.7
 3.5
 1.4
 1.4
 1.3
 1.7
 0.0
26 Rnf4 ring finger protein 4 29274 2.2 2.3
 -0.0
 3.1
 0.9
 1.2
 0.5
 -0.2
 -0.1
27 Mafg MAF bZIP transcription factor G 64188 2.2 3.7
 1.3
 3.0
2.0
 0.6
0.2
 1.7
1.4
 2.0
0.5
 2.1
1.6
 1.3
0.8
28 Ikzf5 IKAROS family zinc finger 5 309031 2.2 3.1
 0.8
 2.4
 3.3
 2.1
 1.8
 1.0
 1.8
29 Atp6v1d ATPase H+ transporting V1 subunit D 299159 2.2 4.7
 2.3
 2.1
 0.9
 0.5
 0.7
 1.1
 -0.7
30 Dctn4 dynactin subunit 4 84428 2.2 3.6
 1.3
 3.0
 4.0
 1.2
 -0.9
 1.0
 1.0
31 Ppp1r2 protein phosphatase 1, regulatory (inhibitor) subunit 2 192361 2.2 3.8
 1.5
 2.7
 -0.2
 1.0
 2.4
 -0.0
 0.9
32 Lin7c lin-7 homolog C, crumbs cell polarity complex component 60442 2.2 3.0
 0.7
 3.1
-1.3
 3.3
1.2
 1.7
0.1
 0.7
-0.3
 1.9
0.4
 0.2
-0.5
33 Mak16 MAK16 homolog 306526 2.1 4.7
 2.4
 3.7
 2.4
 1.8
 1.5
 0.6
 0.5
34 Casp3 caspase 3 25402 2.1 2.8
 0.6
 1.7
0.4
 2.1
0.5
 3.0
2.4
 1.8
0.8
 0.8
0.4
 2.0
0.8
35 Rab6a RAB6A, member RAS oncogene family 84379 2.1 2.1
 -0.1
 0.9
 1.8
0.3
 1.3
0.3
 2.1
-0.9
 0.5
-0.4
 0.7
0.2
36 Phlda2 pleckstrin homology-like domain, family A, member 2 293637 2.1 3.3
 1.1
 0.1
 0.1
 -0.4
 1.5
 0.6
 1.6
37 Usp15 ubiquitin specific peptidase 15 171329 2.1 4.1
 1.8
 1.7
-0.3
 2.5
-0.1
 0.1
-0.6
 -0.9
-1.3
 3.1
1.4
 0.9
0.9
38 Commd3 COMM domain containing 3 291339 2.1 3.6
 1.3
 3.9
 -0.1
 -0.8
 0.1
 1.2
 -0.2
39 Caprin1 cell cycle associated protein 1 362173 2.1 2.3
 0.2
 1.4
0.4
 0.3
-0.9
 1.7
-0.2
 0.7
0.7
 0.9
-0.5
 1.3
1.2
40 Gtf2h1 general transcription factor IIH subunit 1 361580 2.1 4.0
 1.8
 4.3
 1.4
 0.5
 1.2
 1.3
 1.3
41 Arih2 ariadne RBR E3 ubiquitin protein ligase 2 316005 2.1 4.7
 2.4
 3.4
-1.3
 2.7
 1.2
 1.6
42 Atf2 activating transcription factor 2 81647 2.1 2.0
 -0.1
 1.8
-0.1
 -1.3
 1.5
1.0
 1.3
0.0
 0.9
0.4
 1.6
0.2
43 Nfe2l2 nuclear factor, erythroid 2-like 2 83619 2.1 4.0
 1.8
 1.7
-1.0
 3.0
-0.7
 1.1
-0.5
 2.1
-1.8
 0.3
 1.6
1.3
44 Map4k5 mitogen-activated protein kinase kinase kinase kinase 5 503027 2.1 2.9
 0.8
 3.2
0.9
 1.9
1.3
 0.6
0.4
 1.0
0.6
 0.9
-0.6
 1.0
0.6
45 Rbm18 RNA binding motif protein 18 311902 2.0 3.9
 1.7
 3.8
 1.4
 0.6
 2.5
 0.6
 0.6
46 Rlim ring finger protein, LIM domain interacting 317241 2.0 2.5
 0.4
 2.5
 2.3
 3.4
 0.4
 2.0
 -0.7
47 Fbxo30 F-box protein 30 308283 2.0 4.7
 2.5
 3.7
0.6
 1.4
-0.3
 0.5
0.4
 2.0
-0.2
 1.4
-0.4
 0.7
0.2
48 Stk17b serine/threonine kinase 17b 170904 2.0 3.8
 1.7
 1.1
 2.4
1.0
 2.3
0.6
 1.0
0.3
 0.7
0.5
 0.9
0.5
49 Gpbp1 GC-rich promoter binding protein 1 294734 2.0 3.8
 1.7
 4.5
 2.4
 0.7
 1.1
 0.2
50 Akirin2 akirin 2 297968 2.0 4.0
 1.9
 3.6
2.4
 1.9
0.9
 1.8
1.3
 0.6
-0.1
 0.4
 2.0
0.8
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